LV10870B - Novel derivatives of phospholipids - Google Patents

Novel derivatives of phospholipids Download PDF

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Publication number
LV10870B
LV10870B LVP-93-988A LV930988A LV10870B LV 10870 B LV10870 B LV 10870B LV 930988 A LV930988 A LV 930988A LV 10870 B LV10870 B LV 10870B
Authority
LV
Latvia
Prior art keywords
compound
treatment
phosphate
mmol
active ingredient
Prior art date
Application number
LVP-93-988A
Other languages
English (en)
Latvian (lv)
Other versions
LV10870A (lv
Inventor
Gerhard Noessner
Bernhard Kutscher
Juergen Engel
Wolfgang Schumacher
Jurij Stekar
Peter Hilgard
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of LV10870A publication Critical patent/LV10870A/xx
Publication of LV10870B publication Critical patent/LV10870B/lv

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • C07F9/106Adducts, complexes, salts of phosphatides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532Seven-(or more) membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
LVP-93-988A 1992-07-11 1993-07-12 Novel derivatives of phospholipids LV10870B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4222910A DE4222910A1 (de) 1992-07-11 1992-07-11 Neue Phospholipidderivate

Publications (2)

Publication Number Publication Date
LV10870A LV10870A (lv) 1995-10-20
LV10870B true LV10870B (en) 1996-06-20

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-988A LV10870B (en) 1992-07-11 1993-07-12 Novel derivatives of phospholipids

Country Status (31)

Country Link
EP (1) EP0579939B1 (xx)
JP (1) JP3311431B2 (xx)
KR (1) KR100297180B1 (xx)
CN (1) CN1039012C (xx)
AT (1) ATE176477T1 (xx)
AU (1) AU664101B2 (xx)
BR (1) BR9302809A (xx)
CA (2) CA2100228C (xx)
CZ (1) CZ290863B6 (xx)
DE (2) DE4222910A1 (xx)
DK (1) DK0579939T3 (xx)
EE (1) EE03140B1 (xx)
ES (1) ES2129053T3 (xx)
FI (1) FI111262B (xx)
GR (1) GR3029602T3 (xx)
HR (1) HRP931046B1 (xx)
HU (1) HU218783B (xx)
IL (1) IL106289A (xx)
LT (1) LT3113B (xx)
LV (1) LV10870B (xx)
MX (1) MX9304133A (xx)
NO (1) NO306468B1 (xx)
PL (3) PL175607B1 (xx)
RU (1) RU2108336C1 (xx)
SG (1) SG46249A1 (xx)
SI (1) SI9300365B (xx)
SK (1) SK283827B6 (xx)
TW (1) TW304956B (xx)
UA (1) UA40567C2 (xx)
YU (1) YU49079B (xx)
ZA (1) ZA934971B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006077424A1 (en) 2005-01-21 2006-07-27 Astex Therapeutics Limited Pharmaceutical compounds
AR058397A1 (es) * 2005-12-19 2008-01-30 Zentaris Gmbh Derivados de alquilfosfolipidos con citotoxicidad reducida y usos de los mismos
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
EP1869981A1 (de) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3164332D1 (en) * 1980-10-21 1984-07-26 Boehringer Mannheim Gmbh Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
DE3530767A1 (de) * 1985-08-28 1987-03-12 Max Planck Gesellschaft Mittel gegen multiple sklerose
IE59778B1 (en) * 1985-12-04 1994-04-06 Max Planck Gesellschaft Medicament with anti-tumour action containing hexadecylphosphocholine
DE3765502D1 (de) * 1986-07-14 1990-11-15 Nippon Chemiphar Co Glycerolderivat und antihypertensives mittel.
ES2058260T3 (es) * 1987-03-24 1994-11-01 Nippon Chemiphar Co Un proceso para la preparacion de un derivado del glicerol.
DE3906952A1 (de) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel
DE3942933A1 (de) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate
DE4114586A1 (de) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
FI111262B (fi) 2003-06-30
AU4186493A (en) 1994-01-13
DK0579939T3 (da) 1999-09-20
LV10870A (lv) 1995-10-20
CN1084175A (zh) 1994-03-23
HUT64548A (en) 1994-01-28
ES2129053T3 (es) 1999-06-01
HU218783B (hu) 2000-12-28
NO306468B1 (no) 1999-11-08
GR3029602T3 (en) 1999-06-30
NO932502D0 (no) 1993-07-08
SK67093A3 (en) 1995-03-08
EP0579939A1 (de) 1994-01-26
IL106289A (en) 2000-06-01
KR100297180B1 (ko) 2001-11-30
PL175607B1 (pl) 1999-01-29
TW304956B (xx) 1997-05-11
FI933165A0 (fi) 1993-07-09
NO932502L (no) 1994-01-12
LTIP620A (en) 1994-07-15
CZ124993A3 (en) 1995-03-15
DE59309355D1 (de) 1999-03-18
EE03140B1 (et) 1998-12-15
HRP931046A2 (en) 1997-04-30
CA2100228C (en) 2006-01-24
ATE176477T1 (de) 1999-02-15
CA2511753A1 (en) 1994-01-12
YU49079B (sh) 2003-08-29
MX9304133A (es) 1994-04-29
IL106289A0 (en) 1994-04-12
PL173388B1 (pl) 1998-02-27
UA40567C2 (uk) 2001-08-15
HRP931046B1 (en) 2000-06-30
ZA934971B (en) 1994-02-01
SI9300365A (en) 1994-03-31
KR940002265A (ko) 1994-02-17
JP3311431B2 (ja) 2002-08-05
SK283827B6 (sk) 2004-02-03
CZ290863B6 (cs) 2002-11-13
HU9301992D0 (en) 1993-09-28
RU2108336C1 (ru) 1998-04-10
CN1039012C (zh) 1998-07-08
PL299624A1 (en) 1994-02-21
AU664101B2 (en) 1995-11-02
BR9302809A (pt) 1994-03-15
CA2100228A1 (en) 1994-01-12
FI933165A (fi) 1994-01-12
YU47393A (sh) 1997-08-22
DE4222910A1 (de) 1994-01-13
CA2511753C (en) 2007-09-25
LT3113B (en) 1994-12-27
SG46249A1 (en) 1998-02-20
PL177811B1 (pl) 2000-01-31
SI9300365B (sl) 2002-02-28
JPH0733791A (ja) 1995-02-03
EP0579939B1 (de) 1999-02-03

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