FI933165A - Nya fosfolipidderivat - Google Patents

Nya fosfolipidderivat Download PDF

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Publication number
FI933165A
FI933165A FI933165A FI933165A FI933165A FI 933165 A FI933165 A FI 933165A FI 933165 A FI933165 A FI 933165A FI 933165 A FI933165 A FI 933165A FI 933165 A FI933165 A FI 933165A
Authority
FI
Finland
Prior art keywords
fospholipidderivat
nya
medicaments
preparation processes
phospholipid derivatives
Prior art date
Application number
FI933165A
Other languages
English (en)
Other versions
FI111262B (fi
FI933165A0 (fi
Inventor
Gerhard Noessner
Bernhard Kutscher
Juergen Engel
Wolfgang Schumacher
Jurij Stekar
Peter Hilgard
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of FI933165A0 publication Critical patent/FI933165A0/fi
Publication of FI933165A publication Critical patent/FI933165A/fi
Application granted granted Critical
Publication of FI111262B publication Critical patent/FI111262B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • C07F9/106Adducts, complexes, salts of phosphatides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532Seven-(or more) membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
FI933165A 1992-07-11 1993-07-09 Menetelmä terapeuttisesti käyttökelpoisten fosfolipidijohdannaisten valmistamiseksi FI111262B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4222910A DE4222910A1 (de) 1992-07-11 1992-07-11 Neue Phospholipidderivate
DE4222910 1992-07-11

Publications (3)

Publication Number Publication Date
FI933165A0 FI933165A0 (fi) 1993-07-09
FI933165A true FI933165A (fi) 1994-01-12
FI111262B FI111262B (fi) 2003-06-30

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933165A FI111262B (fi) 1992-07-11 1993-07-09 Menetelmä terapeuttisesti käyttökelpoisten fosfolipidijohdannaisten valmistamiseksi

Country Status (31)

Country Link
EP (1) EP0579939B1 (fi)
JP (1) JP3311431B2 (fi)
KR (1) KR100297180B1 (fi)
CN (1) CN1039012C (fi)
AT (1) ATE176477T1 (fi)
AU (1) AU664101B2 (fi)
BR (1) BR9302809A (fi)
CA (2) CA2511753C (fi)
CZ (1) CZ290863B6 (fi)
DE (2) DE4222910A1 (fi)
DK (1) DK0579939T3 (fi)
EE (1) EE03140B1 (fi)
ES (1) ES2129053T3 (fi)
FI (1) FI111262B (fi)
GR (1) GR3029602T3 (fi)
HR (1) HRP931046B1 (fi)
HU (1) HU218783B (fi)
IL (1) IL106289A (fi)
LT (1) LT3113B (fi)
LV (1) LV10870B (fi)
MX (1) MX9304133A (fi)
NO (1) NO306468B1 (fi)
PL (3) PL173388B1 (fi)
RU (1) RU2108336C1 (fi)
SG (1) SG46249A1 (fi)
SI (1) SI9300365B (fi)
SK (1) SK283827B6 (fi)
TW (1) TW304956B (fi)
UA (1) UA40567C2 (fi)
YU (1) YU49079B (fi)
ZA (1) ZA934971B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080161251A1 (en) 2005-01-21 2008-07-03 Astex Therapeutics Limited Pharmaceutical Compounds
EP1962862B1 (en) 2005-12-19 2013-09-04 Æterna Zentaris GmbH Alkyl phospholipid derivatives with reduced cytotoxicity and uses therof
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
EP1869981A1 (de) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3164332D1 (en) * 1980-10-21 1984-07-26 Boehringer Mannheim Gmbh Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
DE3530767A1 (de) * 1985-08-28 1987-03-12 Max Planck Gesellschaft Mittel gegen multiple sklerose
CA1338627C (en) * 1985-12-04 1996-10-01 Hansjorg Eibl Pharmaceuticals based on phosphoric acid esters for use in tumor therapy, and process for their preparation
JP2512311B2 (ja) * 1986-07-14 1996-07-03 日本ケミファ株式会社 新規なグリセリン誘導体及び血圧降下剤
CN1017435B (zh) * 1987-03-24 1992-07-15 日本化学医药株式会社 新的甘油衍生物的制备方法
DE3906952A1 (de) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel
DE3942933A1 (de) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate
DE4114586A1 (de) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
JPH0733791A (ja) 1995-02-03
CA2100228A1 (en) 1994-01-12
CA2511753C (en) 2007-09-25
SK283827B6 (sk) 2004-02-03
KR100297180B1 (ko) 2001-11-30
HRP931046A2 (en) 1997-04-30
CN1039012C (zh) 1998-07-08
TW304956B (fi) 1997-05-11
EP0579939B1 (de) 1999-02-03
HUT64548A (en) 1994-01-28
NO932502D0 (no) 1993-07-08
SK67093A3 (en) 1995-03-08
FI111262B (fi) 2003-06-30
NO932502L (no) 1994-01-12
SI9300365A (en) 1994-03-31
UA40567C2 (uk) 2001-08-15
PL175607B1 (pl) 1999-01-29
DE59309355D1 (de) 1999-03-18
MX9304133A (es) 1994-04-29
ZA934971B (en) 1994-02-01
HU218783B (hu) 2000-12-28
ES2129053T3 (es) 1999-06-01
DK0579939T3 (da) 1999-09-20
NO306468B1 (no) 1999-11-08
JP3311431B2 (ja) 2002-08-05
BR9302809A (pt) 1994-03-15
HU9301992D0 (en) 1993-09-28
LTIP620A (en) 1994-07-15
CA2100228C (en) 2006-01-24
SG46249A1 (en) 1998-02-20
HRP931046B1 (en) 2000-06-30
AU664101B2 (en) 1995-11-02
PL177811B1 (pl) 2000-01-31
PL299624A1 (en) 1994-02-21
LV10870B (en) 1996-06-20
AU4186493A (en) 1994-01-13
YU49079B (sh) 2003-08-29
CZ124993A3 (en) 1995-03-15
ATE176477T1 (de) 1999-02-15
GR3029602T3 (en) 1999-06-30
SI9300365B (sl) 2002-02-28
KR940002265A (ko) 1994-02-17
IL106289A0 (en) 1994-04-12
LT3113B (en) 1994-12-27
CN1084175A (zh) 1994-03-23
EP0579939A1 (de) 1994-01-26
RU2108336C1 (ru) 1998-04-10
FI933165A0 (fi) 1993-07-09
CA2511753A1 (en) 1994-01-12
CZ290863B6 (cs) 2002-11-13
YU47393A (sh) 1997-08-22
IL106289A (en) 2000-06-01
DE4222910A1 (de) 1994-01-13
LV10870A (lv) 1995-10-20
EE03140B1 (et) 1998-12-15
PL173388B1 (pl) 1998-02-27

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Owner name: AETERNA ZENTARIS GMBH

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