YU47393A - Novi derivati fosfolipida - Google Patents
Novi derivati fosfolipidaInfo
- Publication number
- YU47393A YU47393A YU47393A YU47393A YU47393A YU 47393 A YU47393 A YU 47393A YU 47393 A YU47393 A YU 47393A YU 47393 A YU47393 A YU 47393A YU 47393 A YU47393 A YU 47393A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- phospholipid derivatives
- new phospholipid
- new
- derivatives
- medicaments
- Prior art date
Links
- 150000003904 phospholipids Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/106—Adducts, complexes, salts of phosphatides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Pronalazak je iz oblasti farmaceutske hemije i odnosi se na nove derivate fosfolipida opšte formule I u kojoj je R alkil sa 10 do 24C atoma, a R1 i R2 su vodonik ili alkil sa 1-6 C atoma, A je jednostruka veza ili jedna od grupa sledećih formula -CH2-CH2-CH2-0- (II) -CH2-CH-0- (IV) CH3; -CH2-CH2-0- (III) -S-(CH2)8-0- (V); -CH - CH-CHo-O- H2C (VI); u je O ili l-3,aminsuOili prirodni brojevi s tim što m+n=2 do 8, kao i na postupak za proizvodnju tog jedinjenja reakcijom jedinjenja formule R-X-A-H (VII) sa fosforoksitrihloridom i reakcijom dobijenog jedinjenja sa jedinjenjem formule gde R, X, A, R1, R2, y, m i n imaju isto značenje kao u formuli I, a u je halogenid, mesilat ili tosilat.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4222910A DE4222910A1 (de) | 1992-07-11 | 1992-07-11 | Neue Phospholipidderivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU47393A true YU47393A (sh) | 1997-08-22 |
| YU49079B YU49079B (sh) | 2003-08-29 |
Family
ID=6463031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU47393A YU49079B (sh) | 1992-07-11 | 1993-07-06 | Novi derivati fosfolipida i postupak za njihovu proizvodnju |
Country Status (31)
| Country | Link |
|---|---|
| EP (1) | EP0579939B1 (sh) |
| JP (1) | JP3311431B2 (sh) |
| KR (1) | KR100297180B1 (sh) |
| CN (1) | CN1039012C (sh) |
| AT (1) | ATE176477T1 (sh) |
| AU (1) | AU664101B2 (sh) |
| BR (1) | BR9302809A (sh) |
| CA (2) | CA2100228C (sh) |
| CZ (1) | CZ290863B6 (sh) |
| DE (2) | DE4222910A1 (sh) |
| DK (1) | DK0579939T3 (sh) |
| EE (1) | EE03140B1 (sh) |
| ES (1) | ES2129053T3 (sh) |
| FI (1) | FI111262B (sh) |
| GR (1) | GR3029602T3 (sh) |
| HR (1) | HRP931046B1 (sh) |
| HU (1) | HU218783B (sh) |
| IL (1) | IL106289A (sh) |
| LT (1) | LT3113B (sh) |
| LV (1) | LV10870B (sh) |
| MX (1) | MX9304133A (sh) |
| NO (1) | NO306468B1 (sh) |
| PL (3) | PL175607B1 (sh) |
| RU (1) | RU2108336C1 (sh) |
| SG (1) | SG46249A1 (sh) |
| SI (1) | SI9300365B (sh) |
| SK (1) | SK283827B6 (sh) |
| TW (1) | TW304956B (sh) |
| UA (1) | UA40567C2 (sh) |
| YU (1) | YU49079B (sh) |
| ZA (1) | ZA934971B (sh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0606480A (pt) | 2005-01-21 | 2008-03-11 | Astex Therapeutics Ltd | compostos farmacêuticos |
| EP1800684A1 (en) * | 2005-12-20 | 2007-06-27 | Zentaris GmbH | Novel alkyl phospholipid derivatives and uses thereof |
| AR058397A1 (es) | 2005-12-19 | 2008-01-30 | Zentaris Gmbh | Derivados de alquilfosfolipidos con citotoxicidad reducida y usos de los mismos |
| EP1869981A1 (de) * | 2006-06-21 | 2007-12-26 | Staatliches Weinbauinstitut Freiburg | Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen |
| WO2008044045A1 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical combinations |
| WO2008044041A1 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical combinations |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444766A (en) * | 1980-10-21 | 1984-04-24 | Boehringer Mannheim Gmbh | Sulfur-containing phospholipid compounds and therapeutic compositions |
| JPS5984824A (ja) * | 1982-11-08 | 1984-05-16 | Takeda Chem Ind Ltd | 抗腫瘍剤 |
| DE3530767A1 (de) * | 1985-08-28 | 1987-03-12 | Max Planck Gesellschaft | Mittel gegen multiple sklerose |
| IE59777B1 (en) * | 1985-12-04 | 1994-04-06 | Max Planck Gesellschaft | Medicaments |
| ES2036210T3 (es) * | 1986-07-14 | 1993-05-16 | Nippon Chemiphar Co., Ltd. | Un procedimiento para la preparacion de un derivado de glicerol. |
| EP0284395B1 (en) * | 1987-03-24 | 1993-06-23 | Nippon Chemiphar Co., Ltd. | Novel glycerol derivative and anti-hypertensive agent |
| DE3906952A1 (de) * | 1989-03-04 | 1990-09-06 | Boehringer Mannheim Gmbh | (3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel |
| DE3942933A1 (de) * | 1989-12-23 | 1991-06-27 | Boehringer Mannheim Gmbh | Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate |
| DE4114586A1 (de) * | 1991-05-04 | 1992-11-05 | Boehringer Mannheim Gmbh | Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung |
-
1992
- 1992-07-11 DE DE4222910A patent/DE4222910A1/de not_active Ceased
-
1993
- 1993-06-01 TW TW082104345A patent/TW304956B/zh not_active IP Right Cessation
- 1993-06-03 AT AT93108904T patent/ATE176477T1/de active
- 1993-06-03 DE DE59309355T patent/DE59309355D1/de not_active Expired - Lifetime
- 1993-06-03 ES ES93108904T patent/ES2129053T3/es not_active Expired - Lifetime
- 1993-06-03 SG SG1996001626A patent/SG46249A1/en unknown
- 1993-06-03 DK DK93108904T patent/DK0579939T3/da active
- 1993-06-03 EP EP93108904A patent/EP0579939B1/de not_active Expired - Lifetime
- 1993-06-04 LT LTIP620A patent/LT3113B/lt not_active IP Right Cessation
- 1993-06-23 CZ CZ19931249A patent/CZ290863B6/cs not_active IP Right Cessation
- 1993-06-28 SK SK670-93A patent/SK283827B6/sk not_active IP Right Cessation
- 1993-07-06 YU YU47393A patent/YU49079B/sh unknown
- 1993-07-08 PL PL93318680A patent/PL175607B1/pl unknown
- 1993-07-08 NO NO932502A patent/NO306468B1/no not_active IP Right Cessation
- 1993-07-08 PL PL93318679A patent/PL177811B1/pl unknown
- 1993-07-08 PL PL93299624A patent/PL173388B1/pl unknown
- 1993-07-08 JP JP16911493A patent/JP3311431B2/ja not_active Expired - Lifetime
- 1993-07-09 HU HU9301992A patent/HU218783B/hu unknown
- 1993-07-09 UA UA93002052A patent/UA40567C2/uk unknown
- 1993-07-09 SI SI9300365A patent/SI9300365B/sl unknown
- 1993-07-09 BR BR9302809A patent/BR9302809A/pt not_active Application Discontinuation
- 1993-07-09 CA CA002100228A patent/CA2100228C/en not_active Expired - Lifetime
- 1993-07-09 HR HR931046A patent/HRP931046B1/xx not_active IP Right Cessation
- 1993-07-09 CA CA002511753A patent/CA2511753C/en not_active Expired - Lifetime
- 1993-07-09 FI FI933165A patent/FI111262B/fi not_active IP Right Cessation
- 1993-07-09 IL IL10628993A patent/IL106289A/xx not_active IP Right Cessation
- 1993-07-09 AU AU41864/93A patent/AU664101B2/en not_active Expired
- 1993-07-09 RU RU93047049A patent/RU2108336C1/ru active
- 1993-07-09 MX MX9304133A patent/MX9304133A/es active IP Right Grant
- 1993-07-09 ZA ZA934971A patent/ZA934971B/xx unknown
- 1993-07-10 KR KR1019930012980A patent/KR100297180B1/ko not_active IP Right Cessation
- 1993-07-10 CN CN93108564A patent/CN1039012C/zh not_active Expired - Lifetime
- 1993-07-12 LV LVP-93-988A patent/LV10870B/lv unknown
-
1994
- 1994-10-25 EE EE9400199A patent/EE03140B1/xx unknown
-
1999
- 1999-03-08 GR GR990400689T patent/GR3029602T3/el unknown
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