ES2104917T3 - Bis-naftalimidas que contienen engarces amido y tioamido como agentes anticancerosos. - Google Patents
Bis-naftalimidas que contienen engarces amido y tioamido como agentes anticancerosos.Info
- Publication number
- ES2104917T3 ES2104917T3 ES92910298T ES92910298T ES2104917T3 ES 2104917 T3 ES2104917 T3 ES 2104917T3 ES 92910298 T ES92910298 T ES 92910298T ES 92910298 T ES92910298 T ES 92910298T ES 2104917 T3 ES2104917 T3 ES 2104917T3
- Authority
- ES
- Spain
- Prior art keywords
- bis
- naftalimidas
- thioamido
- links
- cancer agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE PRESENTAN NUEVOS COMPUESTOS BISNAFTALIMIDA UTILES COMO AGENTES ANTITUMORALES, COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN Y PROCESOS PARA LA PREPARACION DE DICHOS COMPUESTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/676,062 US5206250A (en) | 1991-03-27 | 1991-03-27 | Bis-naphthalimides containing amide and thioamide linkers as anticancer agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2104917T3 true ES2104917T3 (es) | 1997-10-16 |
Family
ID=24713079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92910298T Expired - Lifetime ES2104917T3 (es) | 1991-03-27 | 1992-03-25 | Bis-naftalimidas que contienen engarces amido y tioamido como agentes anticancerosos. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5206250A (es) |
EP (1) | EP0577745B1 (es) |
JP (1) | JP2701980B2 (es) |
AT (1) | ATE156481T1 (es) |
AU (1) | AU1752592A (es) |
CA (1) | CA2106996A1 (es) |
DE (1) | DE69221473T2 (es) |
DK (1) | DK0577745T3 (es) |
ES (1) | ES2104917T3 (es) |
WO (1) | WO1992017454A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2125142A1 (en) * | 1991-12-11 | 1993-06-24 | Jung-Hui Sun | Highly water soluble bis-naphthalimides useful as anticancer agents |
US5235045A (en) * | 1992-03-19 | 1993-08-10 | Microbiomed Corporation | Non-azo naphthalimide dyes |
US5359070A (en) * | 1993-02-11 | 1994-10-25 | The Du Pont Merck Pharmaceutical Company | Unsymmetrical bis-imides as anticancer agents |
US5416089A (en) * | 1993-06-24 | 1995-05-16 | The Du Pont Merck Pharmaceutical Company | Polycyclic and heterocyclic chromophores for bis-imide tumoricidals |
US5766600A (en) * | 1993-08-09 | 1998-06-16 | Microbiomed Corporation | Non-azo naphtalimide dyes and uses for same |
AU7831694A (en) * | 1993-09-24 | 1995-04-10 | Du Pont Merck Pharmaceutical Company, The | Improved methods for preparing bis-imide compounds |
US5604095A (en) * | 1994-07-22 | 1997-02-18 | Cancer Therapy & Research Center | Unsymmetrically linked bisnaphthalimides as antitumor agents |
US5561042A (en) * | 1994-07-22 | 1996-10-01 | Cancer Therapy And Research Center | Diamine platinum naphthalimide complexes as antitumor agents |
US5641782A (en) * | 1995-02-16 | 1997-06-24 | The Dupont Merck Pharmaceutical Company | 3-aromatic and 3-heteroaromatic substituted bisnaphthalimides |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4146720A (en) * | 1976-10-27 | 1979-03-27 | Laboratorios Made, S.A. | N-aminoethyl-substituted-3-nitronaphthalimides |
ES459497A1 (es) * | 1977-06-04 | 1978-04-16 | Made Labor Sa | Un metodo para la preparacion industrial de naftalimidas y sus derivados. |
DE3481120D1 (de) * | 1983-04-01 | 1990-03-01 | Warner Lambert Co | 3,6-disubstituierte-1,8-naphthalimide, verfahren zu ihrer herstellung und ihre verwendung. |
DE3604827A1 (de) * | 1986-02-15 | 1987-08-20 | Bayer Ag | Elektrophotographische toner |
DE3707651A1 (de) * | 1987-03-10 | 1988-09-22 | Knoll Ag | Bis-naphthalimide, ihre herstellung und verwendung |
US5086059A (en) * | 1990-06-07 | 1992-02-04 | Du Pont Merck Pharmaceutical Company | Bis-naphthalimides as anticancer agents |
-
1991
- 1991-03-27 US US07/676,062 patent/US5206250A/en not_active Expired - Fee Related
-
1992
- 1992-03-25 CA CA002106996A patent/CA2106996A1/en not_active Abandoned
- 1992-03-25 WO PCT/US1992/002137 patent/WO1992017454A1/en active IP Right Grant
- 1992-03-25 JP JP4509431A patent/JP2701980B2/ja not_active Expired - Lifetime
- 1992-03-25 ES ES92910298T patent/ES2104917T3/es not_active Expired - Lifetime
- 1992-03-25 DK DK92910298.6T patent/DK0577745T3/da active
- 1992-03-25 AU AU17525/92A patent/AU1752592A/en not_active Abandoned
- 1992-03-25 EP EP92910298A patent/EP0577745B1/en not_active Expired - Lifetime
- 1992-03-25 DE DE69221473T patent/DE69221473T2/de not_active Expired - Fee Related
- 1992-03-25 AT AT92910298T patent/ATE156481T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5206250A (en) | 1993-04-27 |
DE69221473D1 (de) | 1997-09-11 |
EP0577745B1 (en) | 1997-08-06 |
ATE156481T1 (de) | 1997-08-15 |
DK0577745T3 (da) | 1997-09-22 |
EP0577745A1 (en) | 1994-01-12 |
JPH06506226A (ja) | 1994-07-14 |
WO1992017454A1 (en) | 1992-10-15 |
DE69221473T2 (de) | 1998-01-22 |
JP2701980B2 (ja) | 1998-01-21 |
AU1752592A (en) | 1992-11-02 |
CA2106996A1 (en) | 1992-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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