ES2036210T3 - Un procedimiento para la preparacion de un derivado de glicerol. - Google Patents
Un procedimiento para la preparacion de un derivado de glicerol.Info
- Publication number
- ES2036210T3 ES2036210T3 ES198787306211T ES87306211T ES2036210T3 ES 2036210 T3 ES2036210 T3 ES 2036210T3 ES 198787306211 T ES198787306211 T ES 198787306211T ES 87306211 T ES87306211 T ES 87306211T ES 2036210 T3 ES2036210 T3 ES 2036210T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- procedure
- preparation
- rent
- glycerol derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical class OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 title abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical class C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UN DERIVADO DEL GLICEROL, EFECTIVO PARA REDUCIR LA PRESION SANGUINEA, TIENE COMO FORMULA (I) DONDE R1 ES UN GRUPO ALQUILO QUE TIENE DE 10-22 ATOMOS DE CARBONO, R2 ES UN GRUPO ACILO INFERIOR O BENZOILO, R3 Y R4 SON INDEPENDIENTEMENTE HIDROGENO OUN GRUPO ALQUILO DE CADENA RECTA O RAMIFICADA QUE TIENE 1-6 ATOMOS DE CARBONO; R5, R6 Y R7 SON INDEPENDIENTEMENTE HIDROGENO, O UN GRUPO ALQUILO DE CADENA RECTA O RAMIFICADA, UN GRUPO ARILO O UN GRUPO ARALQUILO; Y M Y N SON INDEPENDIENTEMENTE 0 O UN NUMERO POSITIVO BAJO LA CONDICION DE QUE M+N=2-8.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16533086 | 1986-07-14 | ||
JP6219487 | 1987-03-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2036210T3 true ES2036210T3 (es) | 1993-05-16 |
Family
ID=26403252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198787306211T Expired - Lifetime ES2036210T3 (es) | 1986-07-14 | 1987-07-14 | Un procedimiento para la preparacion de un derivado de glicerol. |
Country Status (5)
Country | Link |
---|---|
US (1) | US5053402A (es) |
EP (1) | EP0257762B1 (es) |
JP (1) | JP2512311B2 (es) |
DE (1) | DE3765502D1 (es) |
ES (1) | ES2036210T3 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0284395B1 (en) * | 1987-03-24 | 1993-06-23 | Nippon Chemiphar Co., Ltd. | Novel glycerol derivative and anti-hypertensive agent |
US6172050B1 (en) * | 1992-07-11 | 2001-01-09 | Asta Medica Aktiengesellschaft | Phospholipid derivatives |
DE4222910A1 (de) * | 1992-07-11 | 1994-01-13 | Asta Medica Ag | Neue Phospholipidderivate |
JP5344548B2 (ja) * | 2008-08-08 | 2013-11-20 | ミヨシ油脂株式会社 | リン酸化物 |
JP5608019B2 (ja) * | 2010-09-09 | 2014-10-15 | 大塚化学株式会社 | 環状第4級アンモニウム塩、それを用いた電解質組成物、及び該電解質組成物を用いた電気化学デバイス |
CN106999506A (zh) | 2014-11-26 | 2017-08-01 | 脉管生物生长有限公司 | 氧化脂质以及纤维化的治疗或预防 |
US9771385B2 (en) | 2014-11-26 | 2017-09-26 | Vascular Biogenics Ltd. | Oxidized lipids |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4493832A (en) * | 1981-07-03 | 1985-01-15 | Fujisawa Pharmaceutical Co., Ltd. | Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same |
US4710579A (en) * | 1984-11-09 | 1987-12-01 | Takeda Chemical Industries, Ltd. | 2-(acetoacetyloxy)-3-(octadecyloxy)propyl-3-trimethylammoniopropyl phosphate or a pharmaceutically acceptable salt thereof |
-
1987
- 1987-07-14 ES ES198787306211T patent/ES2036210T3/es not_active Expired - Lifetime
- 1987-07-14 DE DE8787306211T patent/DE3765502D1/de not_active Expired - Fee Related
- 1987-07-14 JP JP62176654A patent/JP2512311B2/ja not_active Expired - Lifetime
- 1987-07-14 EP EP87306211A patent/EP0257762B1/en not_active Expired - Lifetime
-
1989
- 1989-11-22 US US07/438,996 patent/US5053402A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPS6492A (en) | 1989-01-05 |
EP0257762A2 (en) | 1988-03-02 |
JP2512311B2 (ja) | 1996-07-03 |
EP0257762A3 (en) | 1988-05-11 |
EP0257762B1 (en) | 1990-10-10 |
DE3765502D1 (de) | 1990-11-15 |
US5053402A (en) | 1991-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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