YU47010B - Derivati 1,6-naftiridina - Google Patents

Derivati 1,6-naftiridina

Info

Publication number
YU47010B
YU47010B YU14588A YU14588A YU47010B YU 47010 B YU47010 B YU 47010B YU 14588 A YU14588 A YU 14588A YU 14588 A YU14588 A YU 14588A YU 47010 B YU47010 B YU 47010B
Authority
YU
Yugoslavia
Prior art keywords
chained
straight
carbon atoms
branched alkyl
alkyl radical
Prior art date
Application number
YU14588A
Other languages
English (en)
Other versions
YU14588A (en
Inventor
G. Satzinbger
J. Hartenstein
K. Mannhardt
J. Kleinschroth
H. Osswald
G. Weinheimer
E. Fritschi
Original Assignee
Godecke Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19843431303 external-priority patent/DE3431303A1/de
Priority claimed from DE19853502790 external-priority patent/DE3502790A1/de
Application filed by Godecke Ag. filed Critical Godecke Ag.
Publication of YU14588A publication Critical patent/YU14588A/xx
Publication of YU47010B publication Critical patent/YU47010B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Liquid Crystal Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

DERIVATI 1,6-NAFTIRIDINA, opšte formule: naznačen time, što je R1 nesupstituisan ili supstituisan aromatski ili heteroaromatski prsten, R2 je ravan ili razgranati alkil ostatak, koji sadrži do 4 atoma ugljenika ili benzil ostatak, R3 je atom vodonika, ravan ili razgranati alkil ostatak ili alkoksikarbonil ostatak, koji sadrži do 4 atoma ugljenika, R4 je ravan ili razgranati alkil ostatak, koji sadrži do 4 agoma ugljenika, i R5 je karboksilna grupa ili ravan, razgranati ili ciklični alkoksikarbonil ostatak, koji sadrži do 17 atoma ugljenika i proizvoljno takodje sadrži atom kiseonika, sumpora ili azota, kao i njihove farmakološki primenljive soli. Prijava sadrži još 5 zavisnih zahteva.
YU14588A 1984-08-25 1988-01-26 Derivati 1,6-naftiridina YU47010B (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843431303 DE3431303A1 (de) 1984-08-25 1984-08-25 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
DE19853502790 DE3502790A1 (de) 1985-01-29 1985-01-29 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung

Publications (2)

Publication Number Publication Date
YU14588A YU14588A (en) 1991-02-28
YU47010B true YU47010B (sh) 1994-11-15

Family

ID=25824189

Family Applications (2)

Application Number Title Priority Date Filing Date
YU1348/85A YU45000B (en) 1984-08-25 1985-08-23 Process for obtaining derivatives of 1,6-naphtiridine
YU14588A YU47010B (sh) 1984-08-25 1988-01-26 Derivati 1,6-naftiridina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU1348/85A YU45000B (en) 1984-08-25 1985-08-23 Process for obtaining derivatives of 1,6-naphtiridine

Country Status (22)

Country Link
US (1) US4711901A (sh)
EP (1) EP0173933B1 (sh)
KR (1) KR890000706B1 (sh)
AT (1) ATE48276T1 (sh)
AU (1) AU576887B2 (sh)
BG (1) BG43691A3 (sh)
CA (1) CA1263118A (sh)
DE (1) DE3574471D1 (sh)
DK (1) DK165247C (sh)
ES (1) ES8604960A1 (sh)
FI (1) FI80697C (sh)
GR (1) GR852040B (sh)
HU (1) HU194879B (sh)
IE (1) IE58364B1 (sh)
IL (2) IL75987A (sh)
NO (1) NO161493C (sh)
NZ (1) NZ213218A (sh)
PH (4) PH21177A (sh)
PL (1) PL146668B1 (sh)
RO (1) RO92245B (sh)
SU (1) SU1395143A3 (sh)
YU (2) YU45000B (sh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431303A1 (de) * 1984-08-25 1986-02-27 Goedecke Ag 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
DE3906460C1 (sh) * 1989-03-01 1990-11-15 Goedecke Ag, 1000 Berlin, De
DE3906406C1 (sh) * 1989-03-01 1990-10-25 Goedecke Ag, 1000 Berlin, De
DE102006026583A1 (de) 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Aryl-substituierte hetero-bicyclische Verbindungen und ihre Verwendung
DE102006026585A1 (de) 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Substituierte 4-Aryl-1,4-dihydro-1,6-naphthyridine und ihre Verwendung
DE102007009494A1 (de) 2007-02-27 2008-08-28 Bayer Healthcare Ag Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
AU2015295376C1 (en) * 2014-08-01 2020-07-16 Bayer Pharma Aktiengesellschaft Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carbox-amide and the purification thereof for use as an active pharmaceutical ingredient
CN107849043B (zh) * 2015-08-21 2020-10-16 拜耳制药股份公司 用于制备(4s)-4-(4-氰基-2-甲氧基苯基)-5-乙氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-甲酰胺的方法
PE20180555A1 (es) * 2015-08-21 2018-04-02 Bayer Pharma AG Procedimiento para la preparacion de (4s)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetil-1,4-dihidro-1,6-naftiridina-3-carboxamida y para la recuperacion de (4s)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetil-1,4-dihidro-1,6-naftiridina-3-carboxamida por medio de metodos electroquimicos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304914A (en) * 1980-07-07 1981-12-08 Usv Pharmaceutical Corporation Naphthyridone derivatives
DE3327650A1 (de) * 1983-07-30 1985-02-14 Gödecke AG, 1000 Berlin 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von gefaesserkrankungen

Also Published As

Publication number Publication date
YU14588A (en) 1991-02-28
NO161493B (no) 1989-05-16
YU134885A (en) 1988-10-31
ES8604960A1 (es) 1986-03-01
IL75987A (en) 1991-07-18
IL75987A0 (en) 1985-12-31
SU1395143A3 (ru) 1988-05-07
IE852085L (en) 1986-02-25
EP0173933B1 (de) 1989-11-29
RO92245B (ro) 1987-07-31
GR852040B (sh) 1985-12-19
PH24762A (en) 1990-10-01
PH21177A (en) 1987-08-07
CA1263118A (en) 1989-11-21
ATE48276T1 (de) 1989-12-15
KR890000706B1 (ko) 1989-03-27
DE3574471D1 (de) 1990-01-04
PH23411A (en) 1989-07-26
DK384485A (da) 1986-02-26
RO92245A (ro) 1987-07-30
IE58364B1 (en) 1993-09-08
BG43691A3 (en) 1988-07-15
KR860001810A (ko) 1986-03-22
US4711901A (en) 1987-12-08
PH23379A (en) 1989-07-26
DK384485D0 (da) 1985-08-23
DK165247B (da) 1992-10-26
DK165247C (da) 1993-04-26
NO853329L (no) 1986-02-26
FI80697B (fi) 1990-03-30
FI853233L (fi) 1986-02-26
FI853233A0 (fi) 1985-08-22
AU4662685A (en) 1986-02-27
EP0173933A1 (de) 1986-03-12
HUT39448A (en) 1986-09-29
NZ213218A (en) 1990-01-29
PL255118A1 (en) 1986-07-29
HU194879B (en) 1988-03-28
FI80697C (fi) 1990-07-10
YU45000B (en) 1991-06-30
AU576887B2 (en) 1988-09-08
NO161493C (no) 1989-08-23
ES546366A0 (es) 1986-03-01
PL146668B1 (en) 1989-02-28

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