KR20240063185A - 에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 및 테트라히드로이소퀴놀린 유도체 - Google Patents

에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 및 테트라히드로이소퀴놀린 유도체 Download PDF

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KR20240063185A
KR20240063185A KR1020247014021A KR20247014021A KR20240063185A KR 20240063185 A KR20240063185 A KR 20240063185A KR 1020247014021 A KR1020247014021 A KR 1020247014021A KR 20247014021 A KR20247014021 A KR 20247014021A KR 20240063185 A KR20240063185 A KR 20240063185A
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앤드류 피. 크루
이민 치안
한칭 동
징 왕
키이스 알. 혼버거
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아비나스 오퍼레이션스, 인코포레이티드
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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KR1020247014021A 2016-12-01 2017-12-01 에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 및 테트라히드로이소퀴놀린 유도체 Pending KR20240063185A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662429041P 2016-12-01 2016-12-01
US62/429,041 2016-12-01
US201762540049P 2017-08-01 2017-08-01
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