KR20200015575A - 세균 균주를 포함하는 조성물 - Google Patents

세균 균주를 포함하는 조성물 Download PDF

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KR20200015575A
KR20200015575A KR1020197037450A KR20197037450A KR20200015575A KR 20200015575 A KR20200015575 A KR 20200015575A KR 1020197037450 A KR1020197037450 A KR 1020197037450A KR 20197037450 A KR20197037450 A KR 20197037450A KR 20200015575 A KR20200015575 A KR 20200015575A
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composition
strain
present
compositions
acid
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Korean (ko)
Inventor
임케 엘리자베스 멀더
안나 에토르
수아드 아메드
파테나 포티아두
사만다 유일리
조셉 로비 이링안 우르치아
헬렌 사비그낙
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4디 파마 리서치 리미티드
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Priority claimed from GBGB1709468.1A external-priority patent/GB201709468D0/en
Priority claimed from GBGB1709534.0A external-priority patent/GB201709534D0/en
Priority claimed from GBGB1712851.3A external-priority patent/GB201712851D0/en
Priority claimed from GBGB1803826.5A external-priority patent/GB201803826D0/en
Priority claimed from GBGB1805989.9A external-priority patent/GB201805989D0/en
Priority claimed from GBGB1805990.7A external-priority patent/GB201805990D0/en
Priority claimed from GBGB1805991.5A external-priority patent/GB201805991D0/en
Priority claimed from GBGB1806779.3A external-priority patent/GB201806779D0/en
Priority claimed from GBGB1806780.1A external-priority patent/GB201806780D0/en
Application filed by 4디 파마 리서치 리미티드 filed Critical 4디 파마 리서치 리미티드
Publication of KR20200015575A publication Critical patent/KR20200015575A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0208—Specific bacteria not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020197037450A 2017-06-14 2018-06-14 세균 균주를 포함하는 조성물 Ceased KR20200015575A (ko)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
GBGB1709468.1A GB201709468D0 (en) 2017-06-14 2017-06-14 Compositions comprising bacterial strains
GB1709468.1 2017-06-14
GBGB1709534.0A GB201709534D0 (en) 2017-06-15 2017-06-15 Compositions comprising bacterial strains
GB1709534.0 2017-06-15
GBGB1712851.3A GB201712851D0 (en) 2017-08-10 2017-08-10 Compositions comprising bacterial strains
GB1712851.3 2017-08-10
GBGB1803826.5A GB201803826D0 (en) 2018-03-09 2018-03-09 Compositions comprising bacterial strains
GB1803826.5 2018-03-09
GBGB1805989.9A GB201805989D0 (en) 2018-04-11 2018-04-11 Compositions comprising bacterial strains
GB1805989.9 2018-04-11
GBGB1805990.7A GB201805990D0 (en) 2018-04-11 2018-04-11 Compostions comprising bacterial strains
GB1805991.5 2018-04-11
GB1805990.7 2018-04-11
GBGB1805991.5A GB201805991D0 (en) 2018-04-11 2018-04-11 Compositions comprising bacterial strains
GBGB1806779.3A GB201806779D0 (en) 2018-04-25 2018-04-25 Compositions comprising bacterial strains
GB1806780.1 2018-04-25
GBGB1806780.1A GB201806780D0 (en) 2018-04-25 2018-04-25 Compositions comprising bacterial strains
GB1806779.3 2018-04-25
PCT/EP2018/065903 WO2018229236A2 (en) 2017-06-14 2018-06-14 Compositions comprising bacterial strains

Publications (1)

Publication Number Publication Date
KR20200015575A true KR20200015575A (ko) 2020-02-12

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KR1020197037450A Ceased KR20200015575A (ko) 2017-06-14 2018-06-14 세균 균주를 포함하는 조성물
KR1020197037448A Active KR102519483B1 (ko) 2017-06-14 2018-06-14 메가스파에라 (megasphera) 속의 세균 균주를 포함하는 조성물 및 이들의 용도

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KR1020197037448A Active KR102519483B1 (ko) 2017-06-14 2018-06-14 메가스파에라 (megasphera) 속의 세균 균주를 포함하는 조성물 및 이들의 용도

Country Status (26)

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US (3) US11007233B2 (https=)
EP (4) EP3600364B1 (https=)
JP (4) JP2020523326A (https=)
KR (2) KR20200015575A (https=)
CN (2) CN110913876A (https=)
AU (4) AU2018283994B2 (https=)
BR (2) BR112019026677A2 (https=)
CA (3) CA3066561C (https=)
CY (2) CY1123565T1 (https=)
DK (2) DK3600364T3 (https=)
ES (2) ES2823053T3 (https=)
HR (2) HRP20201629T1 (https=)
HU (2) HUE052258T2 (https=)
IL (3) IL292373A (https=)
LT (2) LT3600364T (https=)
MA (3) MA49010B1 (https=)
MD (2) MD3600364T2 (https=)
MX (2) MX383130B (https=)
PL (2) PL3600364T3 (https=)
PT (2) PT3600364T (https=)
RS (2) RS63393B1 (https=)
SG (2) SG11201912153VA (https=)
SI (2) SI3600364T1 (https=)
SM (2) SMT202000555T1 (https=)
TW (2) TW201919668A (https=)
WO (2) WO2018229216A1 (https=)

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PL3743086T3 (pl) 2018-05-11 2022-06-20 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
EP3870154A4 (en) 2018-10-22 2022-07-27 Research Institute at Nationwide Children's Hospital COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF ANTIBIOTIC-INDUCED PATHOLOGIES USING PROBIOTICS IN BIOFILM STATE
TW202038979A (zh) * 2018-12-12 2020-11-01 英商4D製藥研究有限公司 包含細菌菌株之組成物
EP3979830B1 (en) * 2019-06-03 2025-11-26 Research Institute at Nationwide Children's Hospital Formulations for the treatment of neurodevelopmental deficiencies induced by necrotizing enterocolitis
CA3145904A1 (en) 2019-07-05 2021-01-14 4D Pharma Research Limited Compositions comprising bacterial strains
CN110420228A (zh) * 2019-09-16 2019-11-08 山东大学齐鲁医院 脆弱拟杆菌ych46在制备治疗或辅助治疗高血压的药物中的应用
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JP2022053525A (ja) * 2020-09-24 2022-04-05 森下仁丹株式会社 乳酸産生菌叢の保持剤ならびにそれを用いた経口組成物および乳酸産生菌叢の保持方法
CN112239741B (zh) * 2020-12-10 2022-05-27 慕恩（广州）生物科技有限公司 一种Megasphaera属的细菌MNC-992及其培养方法和应用
US20240058271A1 (en) 2020-12-14 2024-02-22 Kevin Huynh Extracellular vesicle preparations
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TW202304415A (zh) 2021-04-08 2023-02-01 美商艾弗洛生物科技股份有限公司 含有細菌的藥物製劑
US20240226189A1 (en) * 2021-05-12 2024-07-11 Biomica Ltd. Microbiome microorganism and uses thereof
KR20240093504A (ko) 2021-09-24 2024-06-24 에벨로 바이오사이언시즈, 인크. 박테리아 및 미생물 세포외 소포를 함유하는 고체 투여 형태
CN114276948B (zh) * 2021-11-08 2023-06-20 泸州老窖股份有限公司 产己酸的赖氨酸芽孢杆菌及其用途
WO2023107537A1 (en) 2021-12-07 2023-06-15 Evelo Biosciences, Inc. Antibody compositions and methods for utilizing with extracellular vesicles and microbes
WO2023114293A1 (en) 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Extracellular vesicle assays
CN116731894B (zh) * 2021-12-31 2025-05-20 深圳未知君生物科技有限公司 一种巨球形菌菌株及其应用
WO2024015522A1 (en) 2022-07-13 2024-01-18 Evelo Biosciences, Inc. Methods for analyzing extracellular vesicles and microbes
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WO2024229110A1 (en) * 2023-05-01 2024-11-07 The Johns Hopkins University Indole lactate for the treatment of multiple sclerosis
CN117821621B (zh) * 2023-12-15 2024-08-13 深圳未知君生物科技有限公司 一种马氏巨球菌的分子标记及其应用
WO2025264544A1 (en) * 2024-06-20 2025-12-26 The Regents Of The University Of California Compositions and methods for treating neurological disorders
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