JP6552965B2 - 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化 - Google Patents

配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化 Download PDF

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JP6552965B2
JP6552965B2 JP2015547545A JP2015547545A JP6552965B2 JP 6552965 B2 JP6552965 B2 JP 6552965B2 JP 2015547545 A JP2015547545 A JP 2015547545A JP 2015547545 A JP2015547545 A JP 2015547545A JP 6552965 B2 JP6552965 B2 JP 6552965B2
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cas9
crispr
sequences
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JP2016501532A (ja
JP2016501532A5 (enExample
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フェン・ジャン
フェイ・ラン
オフィール・シャレム
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Broad Institute Inc
Harvard University
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
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JP2015547545A 2012-12-12 2013-12-12 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化 Active JP6552965B2 (ja)

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Application Number Priority Date Filing Date Title
US201261736527P 2012-12-12 2012-12-12
US61/736,527 2012-12-12
US201361748427P 2013-01-02 2013-01-02
US61/748,427 2013-01-02
US201361758468P 2013-01-30 2013-01-30
US61/758,468 2013-01-30
US201361769046P 2013-02-25 2013-02-25
US61/769,046 2013-02-25
US201361791409P 2013-03-15 2013-03-15
US201361802174P 2013-03-15 2013-03-15
US61/791,409 2013-03-15
US61/802,174 2013-03-15
US201361806375P 2013-03-28 2013-03-28
US61/806,375 2013-03-28
US201361814263P 2013-04-20 2013-04-20
US61/814,263 2013-04-20
US201361819803P 2013-05-06 2013-05-06
US61/819,803 2013-05-06
US201361828130P 2013-05-28 2013-05-28
US61/828,130 2013-05-28
US201361836101P 2013-06-17 2013-06-17
US201361835931P 2013-06-17 2013-06-17
US61/835,931 2013-06-17
US61/836,101 2013-06-17
PCT/US2013/074691 WO2014093635A1 (en) 2012-12-12 2013-12-12 Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation

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JP2016501532A JP2016501532A (ja) 2016-01-21
JP2016501532A5 JP2016501532A5 (enExample) 2017-02-23
JP6552965B2 true JP6552965B2 (ja) 2019-07-31

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JP2015547545A Active JP6552965B2 (ja) 2012-12-12 2013-12-12 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2016131404A Active JP6395765B2 (ja) 2012-12-12 2016-07-01 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2018119670A Active JP6665230B2 (ja) 2012-12-12 2018-06-25 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2020025253A Active JP7125440B2 (ja) 2012-12-12 2020-02-18 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2022092414A Pending JP2022113766A (ja) 2012-12-12 2022-06-07 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2024128853A Pending JP2024163122A (ja) 2012-12-12 2024-08-05 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化

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JP2018119670A Active JP6665230B2 (ja) 2012-12-12 2018-06-25 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2020025253A Active JP7125440B2 (ja) 2012-12-12 2020-02-18 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2022092414A Pending JP2022113766A (ja) 2012-12-12 2022-06-07 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化
JP2024128853A Pending JP2024163122A (ja) 2012-12-12 2024-08-05 配列操作のための改善された系、方法および酵素組成物のエンジニアリングおよび最適化

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US (6) US20140186919A1 (enExample)
EP (1) EP2898075B1 (enExample)
JP (6) JP6552965B2 (enExample)
KR (1) KR20150105634A (enExample)
CN (2) CN113355357B (enExample)
AU (4) AU2013359212B2 (enExample)
CA (1) CA2894684A1 (enExample)
DK (2) DK2898075T3 (enExample)
ES (2) ES2786193T3 (enExample)
IL (2) IL300461A (enExample)
PL (1) PL2898075T3 (enExample)
PT (1) PT2898075E (enExample)
SG (3) SG10201912327SA (enExample)
WO (1) WO2014093635A1 (enExample)
ZA (1) ZA201504081B (enExample)

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