JP5763046B2 - 嚢胞性線維症膜コンダクタンス制御因子のモジュレーターを作製する方法 - Google Patents
嚢胞性線維症膜コンダクタンス制御因子のモジュレーターを作製する方法 Download PDFInfo
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- JP5763046B2 JP5763046B2 JP2012501023A JP2012501023A JP5763046B2 JP 5763046 B2 JP5763046 B2 JP 5763046B2 JP 2012501023 A JP2012501023 A JP 2012501023A JP 2012501023 A JP2012501023 A JP 2012501023A JP 5763046 B2 JP5763046 B2 JP 5763046B2
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- 0 CCC(C1)=C(*)C=C(C2C=C2)[C@]1N=CC Chemical compound CCC(C1)=C(*)C=C(C2C=C2)[C@]1N=CC 0.000 description 8
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- HFNOECBPRSJRQD-UHFFFAOYSA-N CC(C)(C)c(cc(C(C)(C)CO)c(O)c1)c1NC(C1=CNc2ccccc2C1=O)=O Chemical compound CC(C)(C)c(cc(C(C)(C)CO)c(O)c1)c1NC(C1=CNc2ccccc2C1=O)=O HFNOECBPRSJRQD-UHFFFAOYSA-N 0.000 description 1
- XRWRQOLFLQDWOZ-UHFFFAOYSA-N CC(C)(C)c(cc(c(O)c1)Br)c1[N+]([O-])=O Chemical compound CC(C)(C)c(cc(c(O)c1)Br)c1[N+]([O-])=O XRWRQOLFLQDWOZ-UHFFFAOYSA-N 0.000 description 1
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- C07C229/66—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by doubly-bound oxygen atoms
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- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
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