PT1102765E - Processo para a sintese de derivados de (1h)-benzo¬c|quinolizin-3-onas - Google Patents
Processo para a sintese de derivados de (1h)-benzo¬c|quinolizin-3-onasInfo
- Publication number
- PT1102765E PT1102765E PT99941269T PT99941269T PT1102765E PT 1102765 E PT1102765 E PT 1102765E PT 99941269 T PT99941269 T PT 99941269T PT 99941269 T PT99941269 T PT 99941269T PT 1102765 E PT1102765 E PT 1102765E
- Authority
- PT
- Portugal
- Prior art keywords
- benzo
- kinolizin
- synthesis
- ones derivatives
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Carbon And Carbon Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98114524 | 1998-08-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1102765E true PT1102765E (pt) | 2003-12-31 |
Family
ID=8232396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99941269T PT1102765E (pt) | 1998-08-03 | 1999-07-23 | Processo para a sintese de derivados de (1h)-benzo¬c|quinolizin-3-onas |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US6723850B1 (pt) |
| EP (1) | EP1102765B1 (pt) |
| JP (1) | JP2002522435A (pt) |
| KR (1) | KR100624239B1 (pt) |
| CN (1) | CN1128148C (pt) |
| AT (1) | ATE250057T1 (pt) |
| AU (1) | AU751873B2 (pt) |
| BG (1) | BG65062B1 (pt) |
| BR (1) | BR9912870A (pt) |
| CA (1) | CA2338498C (pt) |
| CZ (1) | CZ291648B6 (pt) |
| DE (1) | DE69911430T2 (pt) |
| DK (1) | DK1102765T3 (pt) |
| EA (1) | EA003997B1 (pt) |
| EE (1) | EE04642B1 (pt) |
| ES (1) | ES2203169T3 (pt) |
| HK (1) | HK1037368A1 (pt) |
| HU (1) | HUP0103241A3 (pt) |
| IL (2) | IL141212A0 (pt) |
| NO (1) | NO20010559L (pt) |
| NZ (1) | NZ509243A (pt) |
| PL (1) | PL198963B1 (pt) |
| PT (1) | PT1102765E (pt) |
| SI (1) | SI1102765T1 (pt) |
| SK (1) | SK285438B6 (pt) |
| TR (1) | TR200100286T2 (pt) |
| UA (1) | UA67787C2 (pt) |
| WO (1) | WO2000008019A1 (pt) |
| ZA (1) | ZA200100365B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US8354427B2 (en) * | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| CA2810655C (en) | 2004-06-24 | 2013-12-10 | Vertex Pharmaceuticals Incorporated | Modulators of atp-binding cassette transporters |
| CN101374849A (zh) * | 2005-12-24 | 2009-02-25 | 沃泰克斯药物股份有限公司 | 作为abc转运蛋白调控剂的喹啉-4-酮衍生物 |
| BRPI0620960A2 (pt) | 2005-12-28 | 2011-11-29 | Vertex Pharmaceuticals Incorporated | formas sólidas de n-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-didro-4- oxiquinolina-3- carboxamida |
| US8476442B2 (en) | 2009-03-20 | 2013-07-02 | Vertex Pharmaceutical Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| JP5918256B2 (ja) * | 2010-12-14 | 2016-05-18 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | ストリゴラクタム誘導体および植物成長調節剤としてのこれらの使用 |
| MX2014010253A (es) | 2012-02-27 | 2014-11-12 | Vertex Pharma | Composicion farmaceutica y administraciones de la misma. |
| EP3204358B1 (en) | 2014-10-07 | 2018-09-19 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
| CN105001216B (zh) * | 2015-07-08 | 2017-03-01 | 中国科学院兰州化学物理研究所 | 一种喹嗪酮的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5064961A (en) * | 1989-12-18 | 1991-11-12 | E. R. Squibb & Sons, Inc. | Process for preparing an optically active cyclobutane nucleoside |
| FR2696465B1 (fr) * | 1992-10-02 | 1994-12-23 | Adir | Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| IT1286545B1 (it) * | 1996-02-09 | 1998-07-15 | Antonio Guarna | Derivati benzo(c) chinolizinici,loro preparazione ed uso come inibitori delle 5-alfa-riduttasi |
| JPH09316076A (ja) * | 1996-05-24 | 1997-12-09 | Nippon Paper Ind Co Ltd | ９−置換プリン誘導体及びその抗ウイルス剤としての用途 |
-
1999
- 1999-07-23 CA CA002338498A patent/CA2338498C/en not_active Expired - Fee Related
- 1999-07-23 IL IL14121299A patent/IL141212A0/xx active IP Right Grant
- 1999-07-23 PT PT99941269T patent/PT1102765E/pt unknown
- 1999-07-23 AU AU63123/99A patent/AU751873B2/en not_active Ceased
- 1999-07-23 JP JP2000563652A patent/JP2002522435A/ja active Pending
- 1999-07-23 DE DE69911430T patent/DE69911430T2/de not_active Expired - Fee Related
- 1999-07-23 BR BR9912870-5A patent/BR9912870A/pt not_active Application Discontinuation
- 1999-07-23 HU HU0103241A patent/HUP0103241A3/hu unknown
- 1999-07-23 UA UA2001020777A patent/UA67787C2/uk unknown
- 1999-07-23 DK DK99941269T patent/DK1102765T3/da active
- 1999-07-23 EA EA200100213A patent/EA003997B1/ru not_active IP Right Cessation
- 1999-07-23 SI SI9930419T patent/SI1102765T1/xx unknown
- 1999-07-23 EE EEP200100060A patent/EE04642B1/xx not_active IP Right Cessation
- 1999-07-23 PL PL345802A patent/PL198963B1/pl not_active IP Right Cessation
- 1999-07-23 CZ CZ2001434A patent/CZ291648B6/cs not_active IP Right Cessation
- 1999-07-23 CN CN99809204A patent/CN1128148C/zh not_active Expired - Fee Related
- 1999-07-23 TR TR2001/00286T patent/TR200100286T2/xx unknown
- 1999-07-23 WO PCT/EP1999/005277 patent/WO2000008019A1/en active IP Right Grant
- 1999-07-23 AT AT99941269T patent/ATE250057T1/de not_active IP Right Cessation
- 1999-07-23 ES ES99941269T patent/ES2203169T3/es not_active Expired - Lifetime
- 1999-07-23 NZ NZ509243A patent/NZ509243A/xx not_active IP Right Cessation
- 1999-07-23 KR KR1020017000325A patent/KR100624239B1/ko not_active IP Right Cessation
- 1999-07-23 EP EP99941269A patent/EP1102765B1/en not_active Expired - Lifetime
- 1999-07-23 SK SK167-2001A patent/SK285438B6/sk not_active IP Right Cessation
- 1999-07-23 US US09/743,373 patent/US6723850B1/en not_active Expired - Fee Related
-
2001
- 2001-01-12 ZA ZA200100365A patent/ZA200100365B/en unknown
- 2001-01-30 BG BG105198A patent/BG65062B1/bg unknown
- 2001-02-01 NO NO20010559A patent/NO20010559L/no not_active Application Discontinuation
- 2001-02-01 IL IL141212A patent/IL141212A/en not_active IP Right Cessation
- 2001-11-20 HK HK01108153A patent/HK1037368A1/xx not_active IP Right Cessation
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