BR0016638B1 - compostos anÁlogos de homopiperidilbenzimidazàis substituÍdos como relaxantes féndicos, processo para preparar os mesmos, composiÇço farmacÊutica e processo para preparÁ-la. - Google Patents
compostos anÁlogos de homopiperidilbenzimidazàis substituÍdos como relaxantes féndicos, processo para preparar os mesmos, composiÇço farmacÊutica e processo para preparÁ-la.Info
- Publication number
- BR0016638B1 BR0016638B1 BRPI0016638-3A BR0016638A BR0016638B1 BR 0016638 B1 BR0016638 B1 BR 0016638B1 BR 0016638 A BR0016638 A BR 0016638A BR 0016638 B1 BR0016638 B1 BR 0016638B1
- Authority
- BR
- Brazil
- Prior art keywords
- preparing
- homopiperidylbenzimidazole
- relaxants
- authentic
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99204441 | 1999-12-21 | ||
PCT/EP2000/012858 WO2001046189A1 (en) | 1999-12-21 | 2000-12-14 | Substituted homopiperidinyl benzimidazole analogues as fundic relaxants |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0016638A BR0016638A (pt) | 2002-10-01 |
BR0016638B1 true BR0016638B1 (pt) | 2013-02-05 |
BRPI0016638B8 BRPI0016638B8 (pt) | 2017-04-25 |
Family
ID=8241040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0016638A BRPI0016638B8 (pt) | 1999-12-21 | 2000-12-14 | compostos análogos de homopiperidilbenzimidazóis substituídos como relaxantes fúndicos, processo para preparar os mesmos, composição farmacêutica e processo para prepará-la. |
Country Status (33)
Country | Link |
---|---|
US (1) | US7304052B2 (pt) |
EP (1) | EP1250337B1 (pt) |
JP (1) | JP4852210B2 (pt) |
KR (1) | KR100715351B1 (pt) |
CN (1) | CN100343251C (pt) |
AT (1) | ATE416174T1 (pt) |
AU (1) | AU781144B2 (pt) |
BG (1) | BG65784B1 (pt) |
BR (1) | BRPI0016638B8 (pt) |
CA (1) | CA2393158C (pt) |
CY (1) | CY1108844T1 (pt) |
CZ (1) | CZ299803B6 (pt) |
DE (1) | DE60041001D1 (pt) |
DK (1) | DK1250337T3 (pt) |
EA (1) | EA005851B1 (pt) |
EE (1) | EE05182B1 (pt) |
ES (1) | ES2317856T3 (pt) |
HK (1) | HK1053109B (pt) |
HR (1) | HRP20020518B1 (pt) |
HU (1) | HU229929B1 (pt) |
IL (2) | IL150310A0 (pt) |
MX (1) | MXPA02006346A (pt) |
MY (1) | MY127758A (pt) |
NO (1) | NO322362B1 (pt) |
NZ (1) | NZ518816A (pt) |
PL (1) | PL199678B1 (pt) |
PT (1) | PT1250337E (pt) |
SI (1) | SI1250337T1 (pt) |
SK (1) | SK287113B6 (pt) |
TW (1) | TWI225488B (pt) |
UA (1) | UA73963C2 (pt) |
WO (1) | WO2001046189A1 (pt) |
ZA (1) | ZA200204983B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI225488B (en) | 1999-12-21 | 2004-12-21 | Janssen Pharmaceutica Nv | Derivatives of homopiperidinyl substituted benzimidazole analogues |
JO2352B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
US7160879B2 (en) | 2002-01-10 | 2007-01-09 | Neurogen Corporation | Melanin concentrating hormone receptor ligands: substituted 2-(4-benzyl-piperazin-1-ylmethyl)- and 2-(4-benzyl-diazepan-1-ylmethyl)-1H-benzoimidazole analogues |
CN100567270C (zh) * | 2004-02-19 | 2009-12-09 | 万有制药株式会社 | 磺酰胺衍生物 |
CN101600717B (zh) * | 2007-01-25 | 2013-03-13 | 詹森药业有限公司 | 2-哌嗪-1-基-3h-咪唑并[4,5-b]吡啶衍生物 |
RS54761B1 (sr) | 2010-06-24 | 2016-10-31 | Gilead Sciences | Pirazolo[1,5-a]pirimidini i-triazini kao antiviralni agensi |
EP2643304A2 (en) * | 2010-11-24 | 2013-10-02 | Sequent Scientific Ltd. | A process for preparation of albendazole |
JP2014159375A (ja) * | 2011-06-15 | 2014-09-04 | Takeda Chem Ind Ltd | アゼパン化合物 |
WO2013096681A1 (en) | 2011-12-22 | 2013-06-27 | Gilead Sciences, Inc. | Pyrazolo[1,5-a]pyrimidines as antiviral agents |
LT2838900T (lt) | 2012-04-17 | 2019-11-11 | Gilead Sciences Inc | Junginiai ir būdai, skirti priešvirusinei terapijai |
WO2015091584A1 (en) * | 2013-12-18 | 2015-06-25 | F. Hoffmann-La Roche Ag | Thiazolopyridine compounds, compositions and their use as tyk2 kinase inhibitors |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2060197C3 (de) | 1970-12-08 | 1979-02-22 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von 2-Aminobenzothiazol und dessen N-Alkylsubstitutionsprodukten |
US4093726A (en) * | 1976-12-02 | 1978-06-06 | Abbott Laboratories | N-(2-benzimidazolyl)-piperazines |
ES8101067A1 (es) * | 1978-08-25 | 1980-12-01 | Thomae Gmbh Dr K | Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona |
JPS5879983A (ja) * | 1981-11-06 | 1983-05-13 | Kanebo Ltd | 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物 |
FR2528526A1 (fr) * | 1982-06-09 | 1983-12-16 | Sfr Sa Robinetterie | Butee se fixant dans un alesage d'un dispositif |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
DE3634066A1 (de) * | 1986-10-07 | 1988-04-21 | Boehringer Mannheim Gmbh | Neue 5-alkylbenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
JPH0260197A (ja) * | 1988-08-26 | 1990-02-28 | Nec Corp | パッケージ構造 |
FR2674856B1 (fr) * | 1991-04-05 | 1993-07-30 | Esteve Labor Dr | Nouveaux antihistaminiques non sedatifs, derives de benzimidazole, leur procede de preparation et leur utilisation en tant que medicaments. |
IL101851A (en) * | 1991-06-13 | 1996-05-14 | Janssen Pharmaceutica Nv | History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition |
DE4237656A1 (de) * | 1992-06-13 | 1993-12-16 | Merck Patent Gmbh | Benzimidazolderivate |
CA2138787A1 (en) * | 1992-07-08 | 1994-01-20 | Clifton Augustus Baile | Alleviating stomach ulcers in swine |
ES2048109B1 (es) * | 1992-07-20 | 1994-12-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol. |
ES2172585T3 (es) * | 1994-05-31 | 2002-10-01 | Mitsui Chemicals Inc | Derivado de benzoimidazol. |
FR2766822B1 (fr) * | 1997-07-30 | 2001-02-23 | Adir | Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6150379A (en) * | 1997-11-26 | 2000-11-21 | Axys Pharmaceuticals, Inc. | Compounds and compositions as anticoagulants |
TWI225488B (en) | 1999-12-21 | 2004-12-21 | Janssen Pharmaceutica Nv | Derivatives of homopiperidinyl substituted benzimidazole analogues |
-
2000
- 2000-12-11 TW TW089126315A patent/TWI225488B/zh not_active IP Right Cessation
- 2000-12-14 WO PCT/EP2000/012858 patent/WO2001046189A1/en active IP Right Grant
- 2000-12-14 AU AU21673/01A patent/AU781144B2/en not_active Ceased
- 2000-12-14 SI SI200031019T patent/SI1250337T1/sl unknown
- 2000-12-14 PT PT00985180T patent/PT1250337E/pt unknown
- 2000-12-14 SK SK854-2002A patent/SK287113B6/sk not_active IP Right Cessation
- 2000-12-14 IL IL15031000A patent/IL150310A0/xx unknown
- 2000-12-14 CN CNB008174458A patent/CN100343251C/zh not_active Expired - Fee Related
- 2000-12-14 HU HU0203847A patent/HU229929B1/hu unknown
- 2000-12-14 DE DE60041001T patent/DE60041001D1/de not_active Expired - Lifetime
- 2000-12-14 AT AT00985180T patent/ATE416174T1/de active
- 2000-12-14 ES ES00985180T patent/ES2317856T3/es not_active Expired - Lifetime
- 2000-12-14 PL PL355442A patent/PL199678B1/pl unknown
- 2000-12-14 UA UA2002065092A patent/UA73963C2/uk unknown
- 2000-12-14 EA EA200200700A patent/EA005851B1/ru not_active IP Right Cessation
- 2000-12-14 BR BRPI0016638A patent/BRPI0016638B8/pt not_active IP Right Cessation
- 2000-12-14 CZ CZ20022055A patent/CZ299803B6/cs not_active IP Right Cessation
- 2000-12-14 US US10/169,011 patent/US7304052B2/en not_active Expired - Fee Related
- 2000-12-14 KR KR1020027006004A patent/KR100715351B1/ko not_active IP Right Cessation
- 2000-12-14 NZ NZ518816A patent/NZ518816A/xx not_active IP Right Cessation
- 2000-12-14 MX MXPA02006346A patent/MXPA02006346A/es active IP Right Grant
- 2000-12-14 JP JP2001547099A patent/JP4852210B2/ja not_active Expired - Fee Related
- 2000-12-14 DK DK00985180T patent/DK1250337T3/da active
- 2000-12-14 CA CA2393158A patent/CA2393158C/en not_active Expired - Fee Related
- 2000-12-14 EE EEP200200326A patent/EE05182B1/xx not_active IP Right Cessation
- 2000-12-14 EP EP00985180A patent/EP1250337B1/en not_active Expired - Lifetime
- 2000-12-20 MY MYPI20006015A patent/MY127758A/en unknown
-
2002
- 2002-05-29 BG BG106749A patent/BG65784B1/bg unknown
- 2002-06-13 HR HR20020518A patent/HRP20020518B1/xx not_active IP Right Cessation
- 2002-06-19 IL IL150310A patent/IL150310A/en not_active IP Right Cessation
- 2002-06-20 NO NO20022977A patent/NO322362B1/no not_active IP Right Cessation
- 2002-06-20 ZA ZA200204983A patent/ZA200204983B/en unknown
-
2003
- 2003-07-23 HK HK03105325.2A patent/HK1053109B/zh not_active IP Right Cessation
-
2009
- 2009-03-03 CY CY20091100243T patent/CY1108844T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/02/2013, OBSERVADAS AS CONDICOES LEGAIS. |
|
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] | ||
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 19A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2544 DE 08-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |