EE200100060A - (1H)benso[c]kinolisiin-3-ooni derivaatide sünteesi meetod - Google Patents

(1H)benso[c]kinolisiin-3-ooni derivaatide sünteesi meetod

Info

Publication number
EE200100060A
EE200100060A EEP200100060A EEP200100060A EE200100060A EE 200100060 A EE200100060 A EE 200100060A EE P200100060 A EEP200100060 A EE P200100060A EE P200100060 A EEP200100060 A EE P200100060A EE 200100060 A EE200100060 A EE 200100060A
Authority
EE
Estonia
Prior art keywords
quinolizin
benzo
derivatives
synthesis
compounds
Prior art date
Application number
EEP200100060A
Other languages
English (en)
Inventor
Guarna Antonio
Serio Mario
Giovanni Occhiato Ernesto
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of EE200100060A publication Critical patent/EE200100060A/et
Publication of EE04642B1 publication Critical patent/EE04642B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Carbon And Carbon Compounds (AREA)
EEP200100060A 1998-08-03 1999-07-23 (1H)benso[c]kinolisiin-3-ooni derivaatide sünteesi meetod EE04642B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98114524 1998-08-03
PCT/EP1999/005277 WO2000008019A1 (en) 1998-08-03 1999-07-23 Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives

Publications (2)

Publication Number Publication Date
EE200100060A true EE200100060A (et) 2002-06-17
EE04642B1 EE04642B1 (et) 2006-06-15

Family

ID=8232396

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100060A EE04642B1 (et) 1998-08-03 1999-07-23 (1H)benso[c]kinolisiin-3-ooni derivaatide sünteesi meetod

Country Status (29)

Country Link
US (1) US6723850B1 (et)
EP (1) EP1102765B1 (et)
JP (1) JP2002522435A (et)
KR (1) KR100624239B1 (et)
CN (1) CN1128148C (et)
AT (1) ATE250057T1 (et)
AU (1) AU751873B2 (et)
BG (1) BG65062B1 (et)
BR (1) BR9912870A (et)
CA (1) CA2338498C (et)
CZ (1) CZ291648B6 (et)
DE (1) DE69911430T2 (et)
DK (1) DK1102765T3 (et)
EA (1) EA003997B1 (et)
EE (1) EE04642B1 (et)
ES (1) ES2203169T3 (et)
HK (1) HK1037368A1 (et)
HU (1) HUP0103241A3 (et)
IL (2) IL141212A0 (et)
NO (1) NO20010559L (et)
NZ (1) NZ509243A (et)
PL (1) PL198963B1 (et)
PT (1) PT1102765E (et)
SI (1) SI1102765T1 (et)
SK (1) SK285438B6 (et)
TR (1) TR200100286T2 (et)
UA (1) UA67787C2 (et)
WO (1) WO2000008019A1 (et)
ZA (1) ZA200100365B (et)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
BR122018075478B8 (pt) * 2004-06-24 2023-10-31 Vertex Pharma moduladores de transportadores de cassete de ligação de atp
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
US20090105272A1 (en) * 2005-12-24 2009-04-23 Grootenhuis Peter D J Prodrugs of modulators of ABC transporters
HUE049976T2 (hu) 2005-12-28 2020-11-30 Vertex Pharma N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid amorf alakjának gyógyászati kompozíciói
SG10201504084QA (en) 2009-03-20 2015-06-29 Vertex Pharma Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
MX2013006497A (es) * 2010-12-14 2013-06-28 Syngenta Participations Ag Derivados de estrigolactama y su uso como reguladores del crecimiento de plantas.
CN109966264A (zh) 2012-02-27 2019-07-05 沃泰克斯药物股份有限公司 药物组合物及其施用
CN107250113B (zh) 2014-10-07 2019-03-29 弗特克斯药品有限公司 囊性纤维化跨膜传导调节蛋白的调节剂的共晶
CN105001216B (zh) * 2015-07-08 2017-03-01 中国科学院兰州化学物理研究所 一种喹嗪酮的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064961A (en) * 1989-12-18 1991-11-12 E. R. Squibb & Sons, Inc. Process for preparing an optically active cyclobutane nucleoside
FR2696465B1 (fr) * 1992-10-02 1994-12-23 Adir Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
IT1286545B1 (it) * 1996-02-09 1998-07-15 Antonio Guarna Derivati benzo(c) chinolizinici,loro preparazione ed uso come inibitori delle 5-alfa-riduttasi
JPH09316076A (ja) * 1996-05-24 1997-12-09 Nippon Paper Ind Co Ltd 9−置換プリン誘導体及びその抗ウイルス剤としての用途

Also Published As

Publication number Publication date
UA67787C2 (uk) 2004-07-15
IL141212A (en) 2006-12-31
CA2338498C (en) 2009-05-19
CZ291648B6 (cs) 2003-04-16
HUP0103241A2 (hu) 2002-01-28
SI1102765T1 (en) 2003-12-31
DE69911430D1 (de) 2003-10-23
WO2000008019A1 (en) 2000-02-17
DE69911430T2 (de) 2004-07-22
BR9912870A (pt) 2001-10-16
KR20010074684A (ko) 2001-08-09
CA2338498A1 (en) 2000-02-17
AU6312399A (en) 2000-02-28
PL198963B1 (pl) 2008-08-29
CN1128148C (zh) 2003-11-19
AU751873B2 (en) 2002-08-29
CN1311788A (zh) 2001-09-05
DK1102765T3 (da) 2004-02-02
ES2203169T3 (es) 2004-04-01
EA003997B1 (ru) 2003-12-25
PL345802A1 (en) 2002-01-02
NO20010559D0 (no) 2001-02-01
HK1037368A1 (en) 2002-02-08
EP1102765A1 (en) 2001-05-30
KR100624239B1 (ko) 2006-09-13
NZ509243A (en) 2002-11-26
HUP0103241A3 (en) 2002-10-28
CZ2001434A3 (cs) 2001-08-15
ZA200100365B (en) 2001-07-26
PT1102765E (pt) 2003-12-31
BG65062B1 (bg) 2007-01-31
EA200100213A1 (ru) 2001-08-27
US6723850B1 (en) 2004-04-20
NO20010559L (no) 2001-02-01
SK285438B6 (sk) 2007-01-04
SK1672001A3 (en) 2001-08-06
JP2002522435A (ja) 2002-07-23
EE04642B1 (et) 2006-06-15
IL141212A0 (en) 2002-03-10
EP1102765B1 (en) 2003-09-17
TR200100286T2 (tr) 2001-07-23
ATE250057T1 (de) 2003-10-15
BG105198A (en) 2001-12-29

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20061231

GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20100723