MX361711B - Proceso para producir moduladores del regulador de conductancia transmembrana de fibrosis quistica. - Google Patents
Proceso para producir moduladores del regulador de conductancia transmembrana de fibrosis quistica.Info
- Publication number
- MX361711B MX361711B MX2014003656A MX2014003656A MX361711B MX 361711 B MX361711 B MX 361711B MX 2014003656 A MX2014003656 A MX 2014003656A MX 2014003656 A MX2014003656 A MX 2014003656A MX 361711 B MX361711 B MX 361711B
- Authority
- MX
- Mexico
- Prior art keywords
- cystic fibrosis
- fibrosis transmembrane
- conductance regulator
- transmembrane conductance
- modulators
- Prior art date
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- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
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- C07C205/43—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
La invención proporciona un proceso para la preparación de un compuesto de la Fórmula 1 (ver Fórmula) que comprende acoplar un ácido carboxílico de la Fórmula 2 (ver Fórmula) con una anilina de la Fórmula 3 (ver Fórmula) en presencia de un agente de acoplamiento.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16214809P | 2009-03-20 | 2009-03-20 | |
US24630309P | 2009-09-28 | 2009-09-28 | |
US24856509P | 2009-10-05 | 2009-10-05 | |
PCT/US2010/028069 WO2010108162A1 (en) | 2009-03-20 | 2010-03-19 | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
Publications (1)
Publication Number | Publication Date |
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MX361711B true MX361711B (es) | 2018-12-14 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011009867A MX2011009867A (es) | 2009-03-20 | 2010-03-19 | Proceso para producir moduladores del regulador de conductancia transmembrana de fibrosis quistica. |
MX2014003656A MX361711B (es) | 2009-03-20 | 2010-03-19 | Proceso para producir moduladores del regulador de conductancia transmembrana de fibrosis quistica. |
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