JP5409986B2 - グラム陰性細菌由来のトランスフェリン結合タンパク質およびＨｓｆを含んでなるワクチン組成物 - Google Patents

グラム陰性細菌由来のトランスフェリン結合タンパク質およびＨｓｆを含んでなるワクチン組成物 Download PDF

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JP5409986B2
JP5409986B2 JP2005506111A JP2005506111A JP5409986B2 JP 5409986 B2 JP5409986 B2 JP 5409986B2 JP 2005506111 A JP2005506111 A JP 2005506111A JP 2005506111 A JP2005506111 A JP 2005506111A JP 5409986 B2 JP5409986 B2 JP 5409986B2
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Prior art keywords
immunogenic composition
tbpa
protein
outer membrane
hsf
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2005506111A
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Japanese (ja)
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JP2006505628A5 (enExample
JP2006505628A (ja
Inventor
ベルテ，フランソワ−グザビエ，ジャック
ビーマンズ，ラルフ
デノエル，フィリップ
フェロン，クリスティアーヌ
ゴラジ，カリーヌ
プールマン，ジャン
ウェイナンツ，ヴィンセント
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グラクソスミスクライン バイオロジカルズ ソシエテ アノニム
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31722002&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP5409986(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0218036A external-priority patent/GB0218036D0/en
Priority claimed from GB0218051A external-priority patent/GB0218051D0/en
Priority claimed from GB0218037A external-priority patent/GB0218037D0/en
Priority claimed from GB0218035A external-priority patent/GB0218035D0/en
Priority claimed from GBGB0220199.4A external-priority patent/GB0220199D0/en
Priority claimed from GBGB0220197.8A external-priority patent/GB0220197D0/en
Priority claimed from GB0225531A external-priority patent/GB0225531D0/en
Priority claimed from GB0225524A external-priority patent/GB0225524D0/en
Priority claimed from GB0230164A external-priority patent/GB0230164D0/en
Priority claimed from GB0230170A external-priority patent/GB0230170D0/en
Priority claimed from GB0230168A external-priority patent/GB0230168D0/en
Priority claimed from GB0305028A external-priority patent/GB0305028D0/en
Application filed by グラクソスミスクライン バイオロジカルズ ソシエテ アノニム filed Critical グラクソスミスクライン バイオロジカルズ ソシエテ アノニム
Publication of JP2006505628A publication Critical patent/JP2006505628A/ja
Publication of JP2006505628A5 publication Critical patent/JP2006505628A5/ja
Publication of JP5409986B2 publication Critical patent/JP5409986B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A61K39/1045—Moraxella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2005506111A 2002-08-02 2003-07-31 グラム陰性細菌由来のトランスフェリン結合タンパク質およびＨｓｆを含んでなるワクチン組成物 Expired - Fee Related JP5409986B2 (ja)

Applications Claiming Priority (25)

Application Number Priority Date Filing Date Title
GB0218036.2 2002-08-02
GB0218037.0 2002-08-02
GB0218035.4 2002-08-02
GB0218036A GB0218036D0 (en) 2002-08-02 2002-08-02 Vaccine
GB0218035A GB0218035D0 (en) 2002-08-02 2002-08-02 Vaccine composition
GB0218037A GB0218037D0 (en) 2002-08-02 2002-08-02 Vaccine composition
GB0218051.1 2002-08-02
GB0218051A GB0218051D0 (en) 2002-08-02 2002-08-02 Vaccine composition
GB0220197.8 2002-08-30
GBGB0220197.8A GB0220197D0 (en) 2002-08-30 2002-08-30 Refolding method
GBGB0220199.4A GB0220199D0 (en) 2002-08-30 2002-08-30 Mutant protein and refolding method
GB0220199.4 2002-08-30
GB0225524A GB0225524D0 (en) 2002-11-01 2002-11-01 Vaccine composition
GB0225531A GB0225531D0 (en) 2002-11-01 2002-11-01 Vaccine
GB0225531.3 2002-11-01
GB0225524.8 2002-11-01
GB0230164A GB0230164D0 (en) 2002-12-24 2002-12-24 Vaccine composition
GB0230170A GB0230170D0 (en) 2002-12-24 2002-12-24 Vaccine
GB0230170.3 2002-12-24
GB0230168A GB0230168D0 (en) 2002-12-24 2002-12-24 Vaccine composition
GB0230168.7 2002-12-24
GB0230164.6 2002-12-24
GB0305028A GB0305028D0 (en) 2003-03-05 2003-03-05 Vaccine
GB0305028.3 2003-03-05
PCT/EP2003/008567 WO2004014419A1 (en) 2002-08-02 2003-07-31 Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria

Publications (3)

Publication Number Publication Date
JP2006505628A JP2006505628A (ja) 2006-02-16
JP2006505628A5 JP2006505628A5 (enExample) 2006-09-14
JP5409986B2 true JP5409986B2 (ja) 2014-02-05

Family

ID=31722002

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2005506111A Expired - Fee Related JP5409986B2 (ja) 2002-08-02 2003-07-31 グラム陰性細菌由来のトランスフェリン結合タンパク質およびＨｓｆを含んでなるワクチン組成物
JP2005506114A Pending JP2006506467A (ja) 2002-08-02 2003-07-31 ワクチン組成物
JP2005506112A Expired - Fee Related JP4740738B2 (ja) 2002-08-02 2003-07-31 ワクチン
JP2005506113A Pending JP2006500963A (ja) 2002-08-02 2003-07-31 ワクチン組成物
JP2010237357A Expired - Fee Related JP5414651B2 (ja) 2002-08-02 2010-10-22 ワクチン組成物
JP2011047056A Pending JP2011142916A (ja) 2002-08-02 2011-03-04 ワクチン
JP2012026928A Expired - Fee Related JP5789203B2 (ja) 2002-08-02 2012-02-10 ワクチン組成物

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2005506114A Pending JP2006506467A (ja) 2002-08-02 2003-07-31 ワクチン組成物
JP2005506112A Expired - Fee Related JP4740738B2 (ja) 2002-08-02 2003-07-31 ワクチン
JP2005506113A Pending JP2006500963A (ja) 2002-08-02 2003-07-31 ワクチン組成物
JP2010237357A Expired - Fee Related JP5414651B2 (ja) 2002-08-02 2010-10-22 ワクチン組成物
JP2011047056A Pending JP2011142916A (ja) 2002-08-02 2011-03-04 ワクチン
JP2012026928A Expired - Fee Related JP5789203B2 (ja) 2002-08-02 2012-02-10 ワクチン組成物

Country Status (25)

Country Link
US (9) US20060034854A1 (enExample)
EP (11) EP2258385A3 (enExample)
JP (7) JP5409986B2 (enExample)
KR (6) KR20050039839A (enExample)
CN (2) CN1674933B (enExample)
AU (6) AU2003260357B2 (enExample)
CA (4) CA2489030A1 (enExample)
CO (3) CO5680455A2 (enExample)
CY (3) CY1114243T1 (enExample)
DE (2) DE20321890U1 (enExample)
DK (2) DK2255826T3 (enExample)
ES (3) ES2408251T3 (enExample)
HU (1) HUE029200T2 (enExample)
IL (3) IL165660A0 (enExample)
IS (3) IS7593A (enExample)
LU (1) LU92262I2 (enExample)
MX (3) MXPA05001265A (enExample)
MY (1) MY149591A (enExample)
NO (3) NO20050008L (enExample)
NZ (4) NZ537181A (enExample)
PL (5) PL216662B1 (enExample)
PT (2) PT2255826E (enExample)
SI (2) SI1524993T1 (enExample)
TW (1) TWI360424B (enExample)
WO (4) WO2004014417A2 (enExample)

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