GB0011108D0 - Virulence gene and protein and their use - Google Patents

Virulence gene and protein and their use

Info

Publication number
GB0011108D0
GB0011108D0 GBGB0011108.8A GB0011108A GB0011108D0 GB 0011108 D0 GB0011108 D0 GB 0011108D0 GB 0011108 A GB0011108 A GB 0011108A GB 0011108 D0 GB0011108 D0 GB 0011108D0
Authority
GB
United Kingdom
Prior art keywords
protein
genes
virulence gene
virulence
products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0011108.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emergent Product Development UK Ltd
Original Assignee
Microscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microscience Ltd filed Critical Microscience Ltd
Priority to GBGB0011108.8A priority Critical patent/GB0011108D0/en
Publication of GB0011108D0 publication Critical patent/GB0011108D0/en
Priority to DE60132084T priority patent/DE60132084T2/en
Priority to AT01925742T priority patent/ATE382056T1/en
Priority to EP01925742A priority patent/EP1287024B1/en
Priority to US10/275,026 priority patent/US20040087770A1/en
Priority to RU2002132891/13A priority patent/RU2252224C2/en
Priority to CA002408738A priority patent/CA2408738A1/en
Priority to NZ522277A priority patent/NZ522277A/en
Priority to HU0302481A priority patent/HUP0302481A2/en
Priority to NZ549068A priority patent/NZ549068A/en
Priority to PCT/GB2001/002003 priority patent/WO2001085772A2/en
Priority to CN01809191A priority patent/CN1427892A/en
Priority to KR1020027014876A priority patent/KR20030032948A/en
Priority to EP07114502A priority patent/EP1908839A3/en
Priority to NZ532297A priority patent/NZ532297A/en
Priority to JP2001582371A priority patent/JP2003532404A/en
Priority to AU52422/01A priority patent/AU776508B2/en
Priority to CNA2005101362903A priority patent/CN1840665A/en
Priority to CZ20023642A priority patent/CZ20023642A3/en
Priority to NO20025329A priority patent/NO20025329L/en
Priority to RU2005101623/13A priority patent/RU2005101623A/en
Priority to US11/893,649 priority patent/US20080241151A1/en
Priority to KR1020070087191A priority patent/KR20070102447A/en
Priority to KR1020080067099A priority patent/KR20080080069A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/36—Neisseria

Abstract

A series of genes from Neisseria meningitidis are shown to encode products which are implicated in virulence. The identification of these genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used in the manufacture of vaccines for therapeutic application.
GBGB0011108.8A 2000-05-08 2000-05-08 Virulence gene and protein and their use Ceased GB0011108D0 (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
GBGB0011108.8A GB0011108D0 (en) 2000-05-08 2000-05-08 Virulence gene and protein and their use
CZ20023642A CZ20023642A3 (en) 2000-05-08 2001-05-08 Virulence genes, proteins and their use
PCT/GB2001/002003 WO2001085772A2 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
KR1020027014876A KR20030032948A (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
EP01925742A EP1287024B1 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
US10/275,026 US20040087770A1 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
RU2002132891/13A RU2252224C2 (en) 2000-05-08 2001-05-08 Peptide with neisseria meningitidis antigene activity, polynucleotide encoding the same, vaccine for prevention and treatment of diseases and conditions induced by neisseria meningitidis, (variants), antibody coupling with said peptide
CA002408738A CA2408738A1 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
NZ522277A NZ522277A (en) 2000-05-08 2001-05-08 Virulence genes, proteins and their use intreating diseases associated with infection by Neisseria, including meningitis
HU0302481A HUP0302481A2 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
NZ549068A NZ549068A (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use in treating conditions associated with infection by Neisseria or gram-negative bacteria
DE60132084T DE60132084T2 (en) 2000-05-08 2001-05-08 VIRGIN GENES, PROTEINS AND ITS USE
CN01809191A CN1427892A (en) 2000-05-08 2001-05-08 Virulence genes, proteins and their use
AT01925742T ATE382056T1 (en) 2000-05-08 2001-05-08 VIRULENCE GENES, PROTEINS, AND THEIR USE
EP07114502A EP1908839A3 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
NZ532297A NZ532297A (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use in treating conditions associated with infection by Neisseria or gram-negative bacteria
JP2001582371A JP2003532404A (en) 2000-05-08 2001-05-08 Virulence genes, proteins and their uses
AU52422/01A AU776508B2 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
CNA2005101362903A CN1840665A (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use
NO20025329A NO20025329L (en) 2000-05-08 2002-11-06 Virulence genes, proteins and their use
RU2005101623/13A RU2005101623A (en) 2000-05-08 2005-01-24 VIRULENT GENES, PROTEINS AND THEIR APPLICATION
US11/893,649 US20080241151A1 (en) 2000-05-08 2007-08-17 Virulence genes, proteins, and their use
KR1020070087191A KR20070102447A (en) 2000-05-08 2007-08-29 Virulence genes, proteins, and their use
KR1020080067099A KR20080080069A (en) 2000-05-08 2008-07-10 Virulence genes, proteins, and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0011108.8A GB0011108D0 (en) 2000-05-08 2000-05-08 Virulence gene and protein and their use

Publications (1)

Publication Number Publication Date
GB0011108D0 true GB0011108D0 (en) 2000-06-28

Family

ID=9891203

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0011108.8A Ceased GB0011108D0 (en) 2000-05-08 2000-05-08 Virulence gene and protein and their use

Country Status (16)

Country Link
US (2) US20040087770A1 (en)
EP (2) EP1287024B1 (en)
JP (1) JP2003532404A (en)
KR (3) KR20030032948A (en)
CN (2) CN1840665A (en)
AT (1) ATE382056T1 (en)
AU (1) AU776508B2 (en)
CA (1) CA2408738A1 (en)
CZ (1) CZ20023642A3 (en)
DE (1) DE60132084T2 (en)
GB (1) GB0011108D0 (en)
HU (1) HUP0302481A2 (en)
NO (1) NO20025329L (en)
NZ (3) NZ532297A (en)
RU (2) RU2252224C2 (en)
WO (1) WO2001085772A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ296581A (en) 1994-12-09 2000-02-28 Imp College Innovations Ltd A method of identifying genes identified in a microorganisms ability to adapt to changes in its environment
AU5860599A (en) 1998-09-04 2000-03-27 Creatogen Aktiengesellschaft Attenuated salmonella spi2 mutants as antigen carriers
WO2000055327A2 (en) 1999-03-12 2000-09-21 Smithkline Beecham Biologicals S.A. Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies
GB9910812D0 (en) 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
CA2493124C (en) * 2002-08-02 2014-04-29 Glaxosmithkline Biologicals S.A. Vaccine
GB0330007D0 (en) * 2003-12-23 2004-01-28 Imp College Innovations Ltd Vaccines
KR101730748B1 (en) 2005-04-08 2017-04-26 와이어쓰 엘엘씨 Multivalent pneumococcal polysaccharide-protein conjugate composition
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
CA2700841A1 (en) * 2007-09-27 2009-04-02 The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services Isoindoline compounds for the treatment of spinal muscular atrophy and other uses
EP2326344A4 (en) 2008-06-16 2013-08-07 Prokarium Ltd Salmonella vectored vaccines against chlamydia and methods of use
GB0816447D0 (en) * 2008-09-08 2008-10-15 Glaxosmithkline Biolog Sa Vaccine
CN103124737A (en) * 2010-03-11 2013-05-29 葛兰素史密丝克莱恩生物有限公司 Immunogenic composition or vaccine against Gram-negative bacterial, for example neiserial, infrection or disease
CN111118043B (en) * 2020-01-13 2022-07-05 吉林大学 Sophora alopecuroides SaMET6 gene clone and application thereof
CN116042562B (en) * 2022-03-11 2023-10-20 山东恒鲁生物科技有限公司 Recombinant saccharomycetes and application thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2047043A1 (en) * 1990-07-19 1992-01-20 Allen I. Oliff Class ii protein of the outer membrane of neisseria meningitidis having immune enhancement properties
US5338664A (en) * 1992-12-04 1994-08-16 American Cyanamid Company Assay for detection of bacterial iron transport inhibitors
US6121037A (en) * 1994-10-18 2000-09-19 Stojiljkovic; Igor Bacterial hemoglobin receptor genes
NZ296581A (en) * 1994-12-09 2000-02-28 Imp College Innovations Ltd A method of identifying genes identified in a microorganisms ability to adapt to changes in its environment
FR2751000B1 (en) * 1996-07-12 1998-10-30 Inst Nat Sante Rech Med SPECIFIC DNA FROM NEISSERIA MENINGITIDIS BACTERIA, PROCESSES FOR OBTAINING THEM AND BIOLOGICAL APPLICATIONS
US6472518B1 (en) * 1996-10-24 2002-10-29 Centers For Disease Control And Prevention, As Represented By The Secretary, Department Of Health And Human Services Invasion associated genes from Neisseria meningitidis serogroup B
GB9711964D0 (en) * 1997-06-09 1997-08-06 Medical Res Council Live attenuated vaccines
CA2301332A1 (en) * 1997-08-15 1999-02-25 University Of Utrecht Neisseria lactoferrin binding protein
BR9813930A (en) * 1997-11-06 2006-12-19 Chiron Spa neisserial antigen
BR9910005A (en) * 1998-04-29 2001-01-16 American Cyanamid Co Vaccine composition, processes for immunization against neisseria gonorrhoeae and to prepare a vaccine composition, isolated and purified DNA sequence, plasmid, host cell, process for producing a chimeric recombinant pilin protein from neisseria gonorrhoeae and neisseria meningitidis, chimeric recombinant protein isolated and purified from neisseria gonorhoeae and neisseria meningitidis, and, process for immunization against neisseria muningitidis
GB9811260D0 (en) * 1998-05-26 1998-07-22 Smithkline Beecham Biolog Novel compounds
MXPA01003557A (en) * 1998-10-09 2004-04-05 Chiron Corp Neisseria genomic sequences and methods of their use.
US6610836B1 (en) * 1999-01-29 2003-08-26 Genome Therapeutics Corporation Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics
ES2323845T3 (en) * 1999-04-30 2009-07-27 Novartis Vaccines And Diagnostics, Inc. NEISSERIA GENOMIC SEQUENCES AND USE PROCEDURES.

Also Published As

Publication number Publication date
EP1908839A3 (en) 2008-07-16
ATE382056T1 (en) 2008-01-15
EP1287024B1 (en) 2007-12-26
NO20025329L (en) 2003-01-06
WO2001085772A3 (en) 2002-03-28
KR20080080069A (en) 2008-09-02
CZ20023642A3 (en) 2003-04-16
NO20025329D0 (en) 2002-11-06
KR20030032948A (en) 2003-04-26
NZ522277A (en) 2004-05-28
AU776508B2 (en) 2004-09-09
US20080241151A1 (en) 2008-10-02
CA2408738A1 (en) 2001-11-15
EP1287024A2 (en) 2003-03-05
HUP0302481A2 (en) 2003-10-28
US20040087770A1 (en) 2004-05-06
AU5242201A (en) 2001-11-20
RU2005101623A (en) 2006-07-10
DE60132084T2 (en) 2008-12-11
NZ532297A (en) 2005-07-29
DE60132084D1 (en) 2008-02-07
EP1908839A2 (en) 2008-04-09
CN1840665A (en) 2006-10-04
NZ549068A (en) 2008-03-28
WO2001085772A2 (en) 2001-11-15
JP2003532404A (en) 2003-11-05
CN1427892A (en) 2003-07-02
KR20070102447A (en) 2007-10-18
RU2252224C2 (en) 2005-05-20

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)