|
US4943593A
(en)
|
1988-02-25 |
1990-07-24 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US4965288A
(en)
|
1988-02-25 |
1990-10-23 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5021456A
(en)
|
1988-02-25 |
1991-06-04 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5059714A
(en)
|
1988-02-25 |
1991-10-22 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5252608A
(en)
|
1988-02-25 |
1993-10-12 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5182297A
(en)
|
1988-02-25 |
1993-01-26 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5120764A
(en)
|
1988-11-01 |
1992-06-09 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US4997854A
(en)
|
1989-08-25 |
1991-03-05 |
Trustees Of Boston University |
Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates
|
|
US20030125519A1
(en)
|
1990-08-27 |
2003-07-03 |
Peter Besmer |
Ligand for the c-kit receptor and methods of use thereof
|
|
US6319494B1
(en)
|
1990-12-14 |
2001-11-20 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
|
DE4205148A1
(de)
|
1991-05-25 |
1993-01-21 |
Boehringer Mannheim Gmbh |
Monoklonale antikoerper gegen c-kit
|
|
IL104570A0
(en)
|
1992-03-18 |
1993-05-13 |
Yeda Res & Dev |
Chimeric genes and cells transformed therewith
|
|
US5874540A
(en)
|
1994-10-05 |
1999-02-23 |
Immunomedics, Inc. |
CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
|
|
WO1997027873A1
(en)
|
1996-01-30 |
1997-08-07 |
Brigham & Women's Hospital, Inc. |
Antibodies for modulating cd47-mediated neutrophil transmigration
|
|
CA2226962A1
(en)
|
1998-02-16 |
1999-08-16 |
Marie Sarfati |
Use of binding agents to cd47 and its ligands in the treatment or the prophylaxis of various inflammatory, autoimmune and allergic diseases and in the treatment of graft rejection
|
|
WO2001040307A1
(de)
|
1999-11-30 |
2001-06-07 |
Eberhard-Karls-Universität Tübingen Universitätsklinikum |
Antikörper gegen signal-regulator-proteine
|
|
AU2002315052A1
(en)
|
2001-05-15 |
2002-11-25 |
Emory University |
Polynucleotides and polypeptides relating to the modulation of sirp alpha-cd47
|
|
FR2828206B1
(fr)
|
2001-08-03 |
2004-09-24 |
Centre Nat Rech Scient |
Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
|
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US8435529B2
(en)
|
2002-06-14 |
2013-05-07 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
|
CA2478047C
(en)
|
2002-03-01 |
2014-01-21 |
Immunomedics, Inc. |
Rs7 antibodies
|
|
EP1604665B1
(en)
|
2003-03-10 |
2011-05-11 |
Eisai R&D Management Co., Ltd. |
C-kit kinase inhibitor
|
|
WO2005020921A2
(en)
|
2003-08-29 |
2005-03-10 |
Exelixis, Inc. |
C-kit modulators and methods of use
|
|
CA2545166A1
(en)
|
2003-11-11 |
2005-05-19 |
Chugai Seiyaku Kabushiki Kaisha |
Humanized anti-cd47 antibody
|
|
US8435539B2
(en)
|
2004-02-13 |
2013-05-07 |
Immunomedics, Inc. |
Delivery system for cytotoxic drugs by bispecific antibody pretargeting
|
|
EP1761540B1
(en)
|
2004-05-13 |
2016-09-28 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
|
JP4773434B2
(ja)
|
2004-05-19 |
2011-09-14 |
イムノコア リミテッド |
高親和性ｎｙ−ｅｓｏｔ細胞受容体
|
|
JP2008503473A
(ja)
|
2004-06-17 |
2008-02-07 |
プレキシコン，インコーポレーテッド |
Ｃ−ｋｉｔ活性を調節する化合物
|
|
WO2006031221A1
(en)
|
2004-09-13 |
2006-03-23 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Compositions comprising t cell receptors and methods of use thereof
|
|
CA2591724C
(en)
|
2004-12-17 |
2014-08-05 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1h-phenantrho[9,10-d]imidazoles as mpges-1 inhibitors
|
|
US7442716B2
(en)
|
2004-12-17 |
2008-10-28 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors
|
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
ES2829566T3
(es)
|
2005-03-03 |
2021-06-01 |
Immunomedics Inc |
Anticuerpos L243 humanizados
|
|
US20090142345A1
(en)
|
2005-03-15 |
2009-06-04 |
Takeda Pharmaceutical Company Limited |
Prophylactic/therapeutic agent for cancer
|
|
US20130039861A1
(en)
|
2005-04-06 |
2013-02-14 |
Immunomedics, Inc. |
Dye Conjugated Peptides for Fluorescent Imaging
|
|
WO2006124944A1
(en)
|
2005-05-18 |
2006-11-23 |
Wyeth |
4, 6-diamino-[1,7] naphthyridine-3-carbonitrile inhibitors of tpl2 kinase and methods of making and using the same
|
|
EP1888529A2
(en)
|
2005-05-18 |
2008-02-20 |
Wyeth |
3-cyanoquinoline inhibitors of tpl2 kinase and methods of making and using the same
|
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之胺基二氮雜呯
|
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之８-經取代苯并氮雜呯
|
|
CN101287831B
(zh)
|
2005-09-13 |
2013-05-15 |
国立大学法人三重大学 |
T细胞受体和编码该受体的核酸
|
|
KR100788161B1
(ko)
|
2006-01-06 |
2007-12-21 |
(주)아모레퍼시픽 |
벤즈이미다졸 아민 유도체 또는 아미노퀴놀린 유도체를 함유하는 피부 미백용 조성물
|
|
TW200740776A
(en)
|
2006-02-06 |
2007-11-01 |
Osi Pharm Inc |
N-phenylbenzotriazolyl c-kit inhibitors
|
|
US7420041B2
(en)
|
2006-02-24 |
2008-09-02 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
WO2007124589A1
(en)
|
2006-05-02 |
2007-11-08 |
Merck Frosst Canada Ltd. |
Methods for treating or preventing neoplasias
|
|
US20080131431A1
(en)
|
2006-05-15 |
2008-06-05 |
Viral Logic Systems Technology Corp. |
CD47 related compositions and methods for treating immunological diseases and disorders
|
|
US8404631B2
(en)
|
2006-05-22 |
2013-03-26 |
The Regents Of The University Of California |
Compositions and methods for the delivery of oxygen
|
|
ITMI20061053A1
(it)
|
2006-05-30 |
2007-11-30 |
Manuli Rubber Ind Spa |
Raccordo per tubi flessibili per applicazioni oleodinamiche,industriali e aria condizionata,avente caratteristiche di tenuta migliorate.
|
|
US20090281115A1
(en)
|
2006-06-30 |
2009-11-12 |
Board of Regents, The University of Texas System, a Texas University |
Inhibitors of c-kit and uses thereof
|
|
DE102006058450A1
(de)
|
2006-12-12 |
2008-06-19 |
Eberhard-Karls-Universität Tübingen |
Zubereitungen zur Hemmung der Prostaglandin E2 Synthese
|
|
SI2170888T1
(sl)
|
2007-06-29 |
2015-10-30 |
Gilead Sciences, Inc. |
Purinski derivati in njihova uporaba kot modulatorjev receptorja tipa toll-7
|
|
ES2700141T3
(es)
|
2007-08-02 |
2019-02-14 |
Gilead Biologics Inc |
Anticuerpos inhibidores LOXL2 y usos de los mismos
|
|
EP2573112A1
(en)
|
2007-10-11 |
2013-03-27 |
The Hospital For Sick Children |
Modulation of sirpa - cd47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor
|
|
UY31468A1
(es)
|
2007-11-15 |
2009-07-17 |
|
Derivados bis-(sulfonilamino) en terapia 065
|
|
TW200930369A
(en)
|
2007-11-15 |
2009-07-16 |
Astrazeneca Ab |
Bis-(sulfonylamino) derivatives in therapy
|
|
US20090163586A1
(en)
|
2007-12-20 |
2009-06-25 |
Astrazeneca Ab |
Bis-(Sulfonylamino) Derivatives in Therapy 205
|
|
US20100324086A1
(en)
|
2008-02-19 |
2010-12-23 |
Novasaid Ab |
Compounds and methods
|
|
WO2009117987A2
(de)
|
2008-03-26 |
2009-10-01 |
Universität Tübingen |
Verwendung von boswelliasäuren und synthetischen boswelliasäurederivaten zur hemmung der mikrosomalen prostaglandin e2 synthase und des cathepsin g
|
|
WO2009130242A1
(en)
|
2008-04-23 |
2009-10-29 |
Novasaid Ab |
Low molecular weight derivatives and use thereof in treatment of prostaglandin e synthase related diseases
|
|
EP2119705A1
(en)
|
2008-05-14 |
2009-11-18 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. |
3-Aminocarbozole compound, pharmaceutical composition containing it and preparation method therefor
|
|
DE102008027331A1
(de)
|
2008-06-07 |
2009-12-10 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Verwendung von Indol-3-carbonsäureestern zur Hemmung der mikrosomalen Prostaglandin E2 Synthase
|
|
DE102008015432A1
(de)
|
2008-06-12 |
2009-12-17 |
Eberhard-Karls-Universität Tübingen |
Verwendung von Pirinixinsäure-Derivaten zur Hemmung der Prostaglandin E2 Synthese
|
|
JP5600104B2
(ja)
|
2008-08-01 |
2014-10-01 |
ベンティアールエックス ファーマシューティカルズ， インコーポレイテッド |
Ｔｏｌｌ様受容体アゴニスト処方物およびその使用
|
|
WO2010019702A2
(en)
|
2008-08-12 |
2010-02-18 |
Oncomed Pharmaceuticals, Inc. |
Ddr1-binding agents and methods of use thereof
|
|
UY32138A
(es)
|
2008-09-25 |
2010-04-30 |
Boehringer Ingelheim Int |
Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables
|
|
US8450321B2
(en)
|
2008-12-08 |
2013-05-28 |
Gilead Connecticut, Inc. |
6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
|
|
AU2009333559B2
(en)
|
2008-12-09 |
2015-03-12 |
Gilead Sciences, Inc. |
Modulators of toll-like receptors
|
|
CN102257001A
(zh)
|
2008-12-19 |
2011-11-23 |
诺瓦提斯公司 |
治疗自体免疫和炎性病症的可溶性多肽
|
|
WO2010083253A2
(en)
|
2009-01-14 |
2010-07-22 |
Viral Logic Systems Technology Corp. |
Cd47 related compositions and methods for treating immunological diseases and disorders
|
|
EP3243527B1
(en)
|
2009-02-13 |
2019-06-05 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
UY32470A
(es)
|
2009-03-05 |
2010-10-29 |
Boehringer Ingelheim Int |
Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones
|
|
EP2408819A2
(en)
|
2009-03-20 |
2012-01-25 |
Ludwig Institute for Cancer Research Ltd |
High affinity t-cell receptor-like ny-eso-1 peptide antibodies, methods, and uses thereof
|
|
TWI491606B
(zh)
|
2009-07-13 |
2015-07-11 |
Gilead Sciences Inc |
調節細胞凋亡信號之激酶的抑制劑
|
|
PL2467377T3
(pl)
|
2009-08-18 |
2017-10-31 |
Ventirx Pharmaceuticals Inc |
Podstawione benzoazepiny jako modulatory receptora toll-podobnego
|
|
RU2580320C2
(ru)
|
2009-08-18 |
2016-04-10 |
Вентиркс Фармасьютикалз, Инк. |
Замещенные бензоазепины в качестве модуляторов toll-подобного рецептора
|
|
WO2011023812A1
(en)
|
2009-08-27 |
2011-03-03 |
Novasaid Ab |
Microsomal prostaglandin e synthase-1 (mpges1) inhibitors
|
|
MX2012004706A
(es)
|
2009-10-22 |
2012-06-08 |
Gilead Sciences Inc |
Derivados de purina o deazapurina utiles para el tratamiento de (inter alia) infecciones virales.
|
|
JP5579862B2
(ja)
|
2009-10-23 |
2014-08-27 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ミクロソームプロスタグランジンｅ２シンターゼ−１のインヒビター
|
|
CN102869682B
(zh)
|
2009-11-18 |
2016-10-19 |
曼康公司 |
单克隆抗体及其诊断用途
|
|
EP2506881B1
(en)
|
2009-12-02 |
2024-03-06 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
|
JP2013514795A
(ja)
|
2009-12-22 |
2013-05-02 |
ノバルティス アーゲー |
治療における使用のための四価ｃｄ４７抗体定常領域融合タンパク質
|
|
US8680246B2
(en)
|
2010-02-04 |
2014-03-25 |
Gilead Biologics, Inc. |
Antibodies that bind to lysyl oxidase-like 2 (LOXL2)
|
|
EP4349868A3
(en)
|
2010-05-14 |
2024-08-28 |
The Board of Trustees of the Leland Stanford Junior University |
Humanized and chimeric monoclonal antibodies to cd47
|
|
US9089520B2
(en)
|
2010-05-21 |
2015-07-28 |
Baylor College Of Medicine |
Methods for inducing selective apoptosis
|
|
US8586604B2
(en)
|
2010-08-20 |
2013-11-19 |
Boehringer Ingelheim International Gmbh |
Inhibitors of the microsomal prostaglandin E2 synthase-1
|
|
US8759537B2
(en)
|
2010-08-20 |
2014-06-24 |
Boehringer Ingelheim International Gmbh |
3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
|
|
SI2608809T1
(sl)
|
2010-08-27 |
2019-08-30 |
Gilead Biologics, Inc. |
Protitelesa proti matriksu metaloproteinaze 9
|
|
RU2016118628A
(ru)
|
2010-10-01 |
2018-11-02 |
Вентиркс Фармасьютикалз, Инк. |
Способы лечения аллергических заболеваний
|
|
CN107970451A
(zh)
|
2010-10-01 |
2018-05-01 |
帆德制药股份有限公司 |
Tlr激动剂和联合治疗的治疗应用
|
|
WO2012054825A1
(en)
|
2010-10-22 |
2012-04-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mage-a3 t cell receptors and related materials and methods of use
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
UY33779A
(es)
|
2010-12-10 |
2012-07-31 |
Boehringer Ingelheim Int |
?2-(fenilamino)-1H-bencimidazol-5-carboxamidas novedosas?
|
|
US8466186B2
(en)
|
2010-12-10 |
2013-06-18 |
Boehringer Ingelheim International Gmbh |
Compounds
|
|
WO2012082647A2
(en)
|
2010-12-13 |
2012-06-21 |
The Regents Of The University Of California |
PYRAZOLE INHIBITORS OF COX-2 AND sEH
|
|
AR084174A1
(es)
|
2010-12-21 |
2013-04-24 |
Lilly Co Eli |
Compuestos de imidazol-2-benzamida utiles para el tratamiento de osteoartritis y una composicion farmaceutica
|
|
CA2824779C
(en)
|
2011-01-12 |
2020-01-14 |
Array Biopharma, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
|
ES2620605T3
(es)
|
2011-01-12 |
2017-06-29 |
Ventirx Pharmaceuticals, Inc. |
Benzoazepinas sustituidas como moduladores de receptores tipo Toll
|
|
WO2012110860A1
(en)
|
2011-02-17 |
2012-08-23 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
|
KR101946499B1
(ko)
|
2011-04-08 |
2019-02-11 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
바이러스 감염 치료를 위한 피리미딘 유도체
|
|
AR086044A1
(es)
|
2011-05-12 |
2013-11-13 |
Imclone Llc |
Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos
|
|
SG194852A1
(en)
|
2011-05-18 |
2013-12-30 |
Janssen R & D Ireland |
Quinazoline derivatives for the treatment of viral infections and further diseases
|
|
AR086254A1
(es)
|
2011-05-26 |
2013-11-27 |
Lilly Co Eli |
Derivados de imidazol utiles para el tratamiento de artritis
|
|
WO2012170250A1
(en)
|
2011-06-07 |
2012-12-13 |
Radiation Control Technologies, Inc. |
Morpholino oligonucleotides capable of inhibiting cd47-mediated cellular damage and uses thereof
|
|
SI2746265T1
(sl)
|
2011-08-18 |
2016-03-31 |
Nippon Shinyaku Co., Ltd. |
Heterociklični derivat kot zaviralec mikrosomske prostaglandin-e sintaze (mpges)
|
|
WO2013027802A1
(ja)
|
2011-08-23 |
2013-02-28 |
中外製薬株式会社 |
抗腫瘍活性を有する新規な抗ｄｄｒ１抗体
|
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
|
CA3114877C
(en)
|
2011-09-15 |
2023-09-12 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors recognizing hla-a1- or hla-cw7-restricted mage
|
|
WO2013041865A1
(en)
|
2011-09-22 |
2013-03-28 |
Immunocore Limited |
T cell receptors
|
|
AU2012318580A1
(en)
|
2011-10-04 |
2014-05-22 |
Gilead Calistoga Llc |
Novel quinoxaline inhibitors of PI3K
|
|
US20140242095A1
(en)
|
2011-10-19 |
2014-08-28 |
University Health Network |
Antibodies and antibody fragments targeting sirp-alpha and their use in treating hematologic cancers
|
|
US8871908B2
(en)
|
2011-11-11 |
2014-10-28 |
Rinat Neuroscience Corp. |
Antibodies specific for Trop-2 and their uses
|
|
WO2013072825A1
(en)
|
2011-11-16 |
2013-05-23 |
Glenmark Pharmaceuticals S.A. |
Phtalazinone derivatives as mpegs -1 inhibitors
|
|
US9427464B2
(en)
|
2011-11-22 |
2016-08-30 |
Chiome Bioscience Inc. |
Anti-human TROP-2 antibody having an antitumor activity in vivo
|
|
KR101939710B1
(ko)
|
2011-12-21 |
2019-01-17 |
노비라 테라퓨틱스, 인코포레이티드 |
B형 간염의 항바이러스성 제제
|
|
JP6460796B2
(ja)
|
2012-01-17 |
2019-01-30 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
高親和性ｓｉｒｐ−アルファ試薬
|
|
UY34573A
(es)
|
2012-01-27 |
2013-06-28 |
Gilead Sciences Inc |
Inhibidor de la quinasa que regula la señal de la apoptosis
|
|
WO2013116562A1
(en)
|
2012-02-03 |
2013-08-08 |
Gilead Calistoga Llc |
Compositions and methods of treating a disease with (s)-4 amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile
|
|
EA034778B1
(ru)
|
2012-02-06 |
2020-03-19 |
Инхибркс, Инк. |
Антитела к cd47 и способы их применения
|
|
JP6283320B2
(ja)
|
2012-02-08 |
2018-02-21 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染の治療のためのピペリジノ−ピリミジン誘導体
|
|
US9006257B2
(en)
|
2012-02-09 |
2015-04-14 |
Glenmark Pharmaceuticals S.A. |
Bicyclic compounds as mPGES-1 inhibitors
|
|
WO2013153535A1
(en)
|
2012-04-13 |
2013-10-17 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
|
TWI568722B
(zh)
|
2012-06-15 |
2017-02-01 |
葛蘭馬克製藥公司 |
作爲ｍＰＧＥＳ－１抑制劑之三唑酮化合物
|
|
MX369417B
(es)
|
2012-08-10 |
2019-11-07 |
Janssen Sciences Ireland Uc |
Derivados de alquilpirimidina para el tratamiento de infecciones víricas y otras enfermedades.
|
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
|
CN104981247A
(zh)
|
2012-09-06 |
2015-10-14 |
普莱希科公司 |
用于激酶调节的化合物和方法及其适应症
|
|
AR092662A1
(es)
|
2012-09-24 |
2015-04-29 |
Gilead Sciences Inc |
Anticuerpos anti-ddr1
|
|
EA035327B1
(ru)
|
2012-10-10 |
2020-05-28 |
Янссен Сайенсиз Айрлэнд Юси |
Производные пирроло[3,2-d]пиримидина для лечения вирусных инфекций и других заболеваний
|
|
WO2014064215A1
(en)
|
2012-10-24 |
2014-05-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL
|
|
ES2655843T3
(es)
|
2012-11-16 |
2018-02-21 |
Janssen Sciences Ireland Uc |
Derivados 2-aminoquinazolínicos sustituidos heterocíclicos para el tratamiento de infecciones víricas
|
|
EP4706769A2
(en)
|
2012-12-03 |
2026-03-11 |
NovImmune SA |
Anti-cd47 antibodies and methods of use thereof
|
|
RU2015122228A
(ru)
|
2012-12-12 |
2017-01-19 |
Васкулокс Инк. |
Терапевтические антитела к CD47
|
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
AU2013364070B2
(en)
|
2012-12-21 |
2016-10-27 |
Gilead Calistoga Llc |
Isoquinolinone or quinazolinone phosphatidylinositol 3-kinase inhibitors
|
|
TW201441216A
(zh)
|
2012-12-21 |
2014-11-01 |
Gilead Calistoga Llc |
肌醇磷酯３－激酶的抑制劑
|
|
SMT201800230T1
(it)
|
2012-12-21 |
2018-07-17 |
Plexxikon Inc |
Composti e metodi per la modulazione della chinasi e loro indicazioni
|
|
EP3922643A1
(en)
|
2013-01-07 |
2021-12-15 |
Omniox, Inc. |
Polymeric forms of h-nox proteins
|
|
HUE050390T2
(hu)
|
2013-01-29 |
2020-11-30 |
Max Delbrueck Centrum Fuer Molekulare Medizin Mdc |
MAGE-A 1-t felismerõ nagy aviditású kötõ molekulák
|
|
MY191389A
(en)
|
2013-02-21 |
2022-06-22 |
Janssen Sciences Ireland Uc |
2-aminopyrimidine derivatives for the treatment of viral infections
|
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
|
CA2899577C
(en)
|
2013-04-03 |
2023-10-17 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
|
WO2014167444A1
(en)
|
2013-04-08 |
2014-10-16 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
|
TR201806822T4
(tr)
|
2013-06-14 |
2018-06-21 |
Gilead Calistoga Llc |
Fosfatidilinositol 3-kinaz inhibitörleri.
|
|
GB201313377D0
(en)
|
2013-07-26 |
2013-09-11 |
Adaptimmune Ltd |
T cell receptors
|
|
WO2015059618A1
(en)
|
2013-10-22 |
2015-04-30 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS
|
|
US9290505B2
(en)
|
2013-12-23 |
2016-03-22 |
Gilead Sciences, Inc. |
Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
|
|
PT3088419T
(pt)
|
2013-12-25 |
2019-01-11 |
Daiichi Sankyo Co Ltd |
Conjugado de anticorpo anti-trop2-fármaco
|
|
WO2015134536A1
(en)
|
2014-03-04 |
2015-09-11 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
WO2015138600A2
(en)
|
2014-03-11 |
2015-09-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Anti sirp-alpha antibodies and bi-specific macrophage enhancing antibodies
|
|
DK3129023T3
(da)
|
2014-03-27 |
2021-05-25 |
Eicosis Llc |
Potente opløselige epoxidhydrolase-inhibitorer
|
|
AU2015243849B2
(en)
|
2014-04-10 |
2020-12-17 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Transgene genetic tags and methods of use
|
|
MX368504B
(es)
|
2014-04-14 |
2019-10-04 |
Shanghai hengrui pharmaceutical co ltd |
Derivados de amidas y sales farmaceuticamente aceptables de los mismos, método de preparación de los mismos y aplicación médica de los mismos.
|
|
ES2962260T3
(es)
|
2014-08-08 |
2024-03-18 |
Univ Leland Stanford Junior |
Proteínas de fusión SIRPa alfa-anticuerpo
|
|
WO2016023040A1
(en)
|
2014-08-08 |
2016-02-11 |
Alexo Therapeutics International |
Sirp-alpha variant constructs and uses thereof
|
|
DK3180363T3
(da)
|
2014-08-15 |
2019-11-04 |
Merck Patent Gmbh |
Sirp-alpha-immunoglobulin fusionsproteiner
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
JO3474B1
(ar)
|
2014-08-29 |
2020-07-05 |
Amgen Inc |
مشتقات تيتراهيدرونافثالين التي تثبط بروتين mcl-1
|
|
CA2961950A1
(en)
|
2014-09-28 |
2016-03-31 |
The Regents Of The University Of California |
Modulation of stimulatory and non-stimulatory myeloid cells
|
|
GB201417803D0
(en)
|
2014-10-08 |
2014-11-19 |
Adaptimmune Ltd |
T cell receptors
|
|
JO3581B1
(ar)
|
2014-10-29 |
2020-07-05 |
Lilly Co Eli |
مركبات ميثيل-بيبيريدين جديدة مفيدة لتثبيط إنزيم سينثاز -1 بروستاجلاندين e2 ميكروسومي
|
|
AR102361A1
(es)
|
2014-10-29 |
2017-02-22 |
Lilly Co Eli |
Compuestos de metil-quinolina útiles para inhibir la sintasa-1 de prostaglandina microsomal e2
|
|
MX2017006485A
(es)
|
2014-11-18 |
2018-03-23 |
Janssen Pharmaceutica Nv |
Anticuerpos anti-cd47, metodos y usos.
|
|
CN107406508B
(zh)
|
2014-12-04 |
2022-04-05 |
地中海治疗诊断有限公司 |
人源化的抗trop-2单克隆抗体及其应用
|
|
JP2017537929A
(ja)
|
2014-12-05 |
2017-12-21 |
ジェネンテック， インコーポレイテッド |
Ｐｄ−１軸アンタゴニスト及びｈｐｋ１アンタゴニストを用いたがん治療のための方法及び組成物
|
|
EP3234144B1
(en)
|
2014-12-15 |
2020-08-26 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlled elimination of therapeutic cells
|
|
WO2016109415A1
(en)
|
2014-12-30 |
2016-07-07 |
Celgene Corporation |
Anti-cd47 antibodies and uses thereof
|
|
TWI843184B
(zh)
|
2015-03-04 |
2024-05-21 |
南韓商柳韓洋行股份有限公司 |
結合cd47之抗體治療劑
|
|
WO2016142783A2
(en)
|
2015-03-10 |
2016-09-15 |
Leiden University Medical Center |
T-cell receptors directed against the preferentially expressed antigen of melanoma and uses thereof
|
|
SG10201908269SA
(en)
|
2015-03-17 |
2019-10-30 |
Omniox Inc |
Modulation of tumor immunity by protein-mediated o2 delivery
|
|
CN106188275A
(zh)
|
2015-05-06 |
2016-12-07 |
广州市香雪制药股份有限公司 |
识别ny-eso-1抗原短肽的t细胞受体
|
|
US10358472B2
(en)
|
2015-05-06 |
2019-07-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
High affinity CD47 analogs
|
|
AU2016256911B2
(en)
|
2015-05-07 |
2022-03-31 |
Agenus Inc. |
Anti-OX40 antibodies and methods of use thereof
|
|
CN107921127B
(zh)
|
2015-05-22 |
2022-04-08 |
纪念斯隆-凯特琳癌症中心 |
对于prame肽具有特异性的t细胞受体样抗体
|
|
CN104804093A
(zh)
|
2015-05-27 |
2015-07-29 |
江苏春申堂药业有限公司 |
一种针对cd47的单域抗体
|
|
MA43344A
(fr)
|
2015-05-29 |
2018-04-11 |
Juno Therapeutics Inc |
Composition et procédés de régulation des interactions inhibitrices dans les cellules génétiquement modifiées
|
|
WO2016205042A1
(en)
|
2015-06-16 |
2016-12-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
SIRPα AGONIST ANTIBODY
|
|
KR20180012850A
(ko)
|
2015-06-24 |
2018-02-06 |
유레카 쎄라퓨틱스, 인코포레이티드 |
Ny-eso-1 펩티드/mhc 복합체를 표적화하는 구축물 및 그의 용도
|
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
|
ES2872555T3
(es)
|
2015-06-25 |
2021-11-02 |
Univ Health Network |
Inhibidores de HPK1 y métodos de uso de los mismos
|
|
CN116059395A
(zh)
|
2015-06-29 |
2023-05-05 |
第一三共株式会社 |
用于选择性制造抗体-药物缀合物的方法
|
|
WO2017027422A1
(en)
|
2015-08-07 |
2017-02-16 |
Alexo Therapeutics Inc. |
Constructs having a sirp-alpha domain or variant thereof
|
|
CA2997749A1
(en)
|
2015-09-09 |
2017-03-16 |
Immune Design Corp. |
Ny-eso-1 specific tcrs and methods of use thereof
|
|
HK1250517A1
(zh)
|
2015-09-17 |
2018-12-21 |
Novartis Ag |
增强功效的car t细胞疗法
|
|
WO2017049251A2
(en)
|
2015-09-18 |
2017-03-23 |
Tioma Therapeutics, Inc. |
Therapeutic cd47 antibodies
|
|
HK1257309A1
(zh)
|
2015-09-21 |
2019-10-18 |
Erasmus University Medical Center |
抗-cd47抗体及使用方法
|
|
WO2017076308A1
(zh)
|
2015-11-04 |
2017-05-11 |
广州市香雪制药股份有限公司 |
识别ny-eso-1抗原短肽的tcr
|
|
EP3383914A4
(en)
|
2015-12-02 |
2019-10-30 |
Agenus Inc. |
ANTI-OX40 ANTIBODIES AND METHOD OF USE THEREOF
|
|
WO2017096276A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
|
SG10201912984WA
(en)
|
2015-12-02 |
2020-03-30 |
Agenus Inc |
Antibodies and methods of use thereof
|
|
CA3007022A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
|
CA3006963A1
(en)
|
2015-12-03 |
2017-06-08 |
Ludwig Institute For Cancer Research Ltd. |
Anti-ox40 antibodies and methods of use thereof
|
|
GB201522592D0
(en)
|
2015-12-22 |
2016-02-03 |
Immunocore Ltd |
T cell receptors
|
|
ES2796378T3
(es)
|
2016-01-11 |
2020-11-26 |
Forty Seven Inc |
Anticuerpos monoclonales anti-cd47 humanizados, de ratón o químicos
|
|
WO2017139623A1
(en)
|
2016-02-10 |
2017-08-17 |
Immunomedics, Inc. |
Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
|
|
WO2017147410A1
(en)
|
2016-02-25 |
2017-08-31 |
Amgen Inc. |
Compounds that inhibit mcl-1 protein
|
|
US10858338B2
(en)
|
2016-03-15 |
2020-12-08 |
The Regents Of The University Of California |
Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH)
|
|
CN107286077B
(zh)
|
2016-04-01 |
2021-04-02 |
合肥中科普瑞昇生物医药科技有限公司 |
一种选择性的c-kit激酶抑制剂
|
|
KR102523449B1
(ko)
|
2016-04-08 |
2023-04-19 |
어댑티뮨 리미티드 |
T 세포 수용체
|
|
RU2018138837A
(ru)
|
2016-04-08 |
2020-05-12 |
Адаптимьюн Лимитед |
Т-клеточные рецепторы
|
|
KR20190059874A
(ko)
|
2016-04-08 |
2019-05-31 |
어댑티뮨 리미티드 |
T 세포 수용체
|
|
MA44608B1
(fr)
|
2016-04-08 |
2022-06-30 |
Immunocore Ltd |
Récepteurs des lymphocytes t
|
|
EP3443010B1
(en)
|
2016-04-14 |
2024-08-07 |
Ose Immunotherapeutics |
New anti-sirpa antibodies and their therapeutic applications
|
|
US11352410B2
(en)
|
2016-04-26 |
2022-06-07 |
The United States of American, as represented by the Secretary, Department of Health and Human Service |
Anti-KK-LC-1 T cell receptors
|
|
TW201741340A
(zh)
|
2016-05-09 |
2017-12-01 |
賽基公司 |
Cd47抗體及使用其之方法
|
|
EP3243522A1
(en)
|
2016-05-10 |
2017-11-15 |
Université Pierre et Marie Curie (Paris 6) |
Agonist agents of cd47 inducing programmed cell death and their use in the treatments of diseases associated with defects in programmed cell death
|
|
EA202092442A3
(ru)
|
2016-06-07 |
2021-08-31 |
Джакобио Фармасьютикалс Ко., Лтд. |
Новые гетероциклические производные, применимые в качестве ингибиторов shp2
|
|
CN106084052B
(zh)
|
2016-06-17 |
2019-12-27 |
长春金赛药业股份有限公司 |
抗cd47单克隆抗体及其应用
|
|
ES2800339T3
(es)
|
2016-06-30 |
2020-12-29 |
Gilead Sciences Inc |
4,6-diaminoquinazolinas como moduladores de cuna y métodos de uso de los mismos
|
|
KR102878970B1
(ko)
|
2016-08-03 |
2025-10-30 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
항-SIRPalpha 항체 요법의 대식세포 증진 효능에서 Fc 수용체 참여의 붕괴
|
|
CN106297966A
(zh)
|
2016-08-22 |
2017-01-04 |
广东纳路纳米科技有限公司 |
一种金属纳米线‑抗氧化材料复合的透明导电膜及其制备
|
|
US20180072718A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
|
AR109595A1
(es)
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
|
|
US10280164B2
(en)
|
2016-09-09 |
2019-05-07 |
Incyte Corporation |
Pyrazolopyridone compounds and uses thereof
|
|
IL292977A
(en)
|
2016-09-09 |
2022-07-01 |
Incyte Corp |
Pyrazolopyridine derivatives as modulators of hpk1 and their use in cancer therapy
|
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
|
EP3411071A4
(en)
|
2016-10-20 |
2019-08-28 |
I-Mab |
NOVEL MONOCLONAL CD47 ANTIBODY AND USES THEREOF
|
|
WO2018075960A1
(en)
|
2016-10-21 |
2018-04-26 |
Tioma Therapeutics, Inc. |
Therapeutic cd47 antibodies
|
|
US11352425B2
(en)
|
2016-11-08 |
2022-06-07 |
Absos, Llc |
Anti-CD47 antibodies
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
WO2018097951A1
(en)
|
2016-11-22 |
2018-05-31 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mage-a3/a6 antibodies
|
|
WO2018098280A1
(en)
|
2016-11-22 |
2018-05-31 |
Dana-Farber Cancer Institute, Inc. |
Degradation of protein kinases by conjugation of protein kinase inhibitors with e3 ligase ligand and methods of use
|
|
CN108779179B
(zh)
|
2016-11-28 |
2022-02-08 |
江苏恒瑞医药股份有限公司 |
Cd47抗体、其抗原结合片段及其医药用途
|
|
JP7025426B2
(ja)
|
2016-11-30 |
2022-02-24 |
アリアド ファーマシューティカルズ， インコーポレイテッド |
造血前駆体キナーゼ１（ｈｐｋ１）阻害剤としてのアニリノピリミジンａｓ
|
|
CN110325549B
(zh)
|
2016-12-09 |
2024-03-08 |
艾利妥 |
抗SIRPα抗体及其使用方法
|
|
EA201991197A1
(ru)
|
2016-12-15 |
2020-01-13 |
Ариад Фармасьютикалз, Инк. |
БЕНЗИМИДАЗОЛЬНЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ c-Kit
|
|
MX390347B
(es)
|
2016-12-15 |
2025-03-20 |
Ariad Pharma Inc |
Compuestos de aminotiazol como inhibidores de c-kit.
|
|
EP3558994A4
(en)
|
2016-12-23 |
2021-05-12 |
Arvinas Operations, Inc. |
COMPOUNDS AND METHODS FOR TARGETED DEGRADATION OF FAST ACCELERATED FIBROSARCOMA POLYPEPTIDES
|
|
AU2018207172B2
(en)
|
2017-01-13 |
2023-10-12 |
Mink Therapeutics, Inc. |
T cell receptors that bind to NY-ESO-1 and methods of use thereof
|
|
KR102607101B1
(ko)
|
2017-01-26 |
2023-11-29 |
제트엘아이피 홀딩 리미티드 |
Cd47 항원 결합 유닛 및 그것의 사용
|
|
EP3577109A4
(en)
|
2017-01-31 |
2020-11-18 |
Arvinas Operations, Inc. |
CEREMONY LIGANDS AND BIFUNCTIONAL COMPOUNDS CONTAINING THEM
|
|
JP7132937B2
(ja)
|
2017-03-15 |
2022-09-07 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｈｐｋ１の阻害剤としてのアザインドール
|
|
EP3595708A4
(en)
|
2017-03-15 |
2020-12-16 |
Fred Hutchinson Cancer Research Center |
HIGH AFFINITY MAGE-A1 SPECIFIC TCRS AND THEIR USES
|
|
DE102017106305A1
(de)
|
2017-03-23 |
2018-09-27 |
Immatics Biotechnologies Gmbh |
Neue T-Zellrezeptoren und deren Verwendung in Immuntherapien gegen prame-positive Krebsarten
|
|
WO2018172984A1
(en)
|
2017-03-23 |
2018-09-27 |
Jacobio Pharmaceuticals Co., Ltd. |
Novel heterocyclic derivatives useful as shp2 inhibitors
|
|
US10918734B2
(en)
|
2017-03-27 |
2021-02-16 |
Immunomedics, Inc. |
Treatment of high Trop-2 expressing triple negative breast cancer (TNBC) with sacituzumab govitecan (IMMU-132) overcomes homologous recombination repair (HRR) rescue mediated by Rad51
|
|
BR112019018093A2
(pt)
|
2017-03-30 |
2020-06-16 |
F. Hoffmann-La Roche Ag |
Compostos, composição, método de inibição de hpk1, métodos para melhorar uma resposta imune e para tratar um distúrbio e usos do composto
|
|
SG11201908940UA
(en)
|
2017-03-30 |
2019-10-30 |
Hoffmann La Roche |
Isoquinolines as inhibitors of hpk1
|
|
JP6453507B2
(ja)
|
2017-03-30 |
2019-01-16 |
アムジエン・インコーポレーテツド |
Ｍｃｌ−１タンパク質を阻害する化合物
|
|
WO2018190719A2
(en)
|
2017-04-13 |
2018-10-18 |
Aduro Biotech Holdings, Europe B.V. |
Anti-sirp alpha antibodies
|
|
BR102018007822A2
(pt)
|
2017-04-20 |
2018-11-06 |
Gilead Sciences, Inc. |
composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
|
|
WO2018210795A1
(en)
|
2017-05-16 |
2018-11-22 |
Synthon Biopharmaceuticals B.V. |
ANTI-SIRPα ANTIBODIES
|
|
WO2018217227A1
(en)
|
2017-05-24 |
2018-11-29 |
Immunomedics, Inc. |
Novel anti-pd-1 checkpoint inhibitor antibodies that block binding of pd-l1 to pd-1
|
|
WO2018225732A1
(ja)
|
2017-06-05 |
2018-12-13 |
国立大学法人三重大学 |
Ｍａｇｅ－ａ４由来ペプチドを認識する抗原結合性タンパク質
|
|
CN108976278B
(zh)
|
2017-06-05 |
2021-04-06 |
海创药业股份有限公司 |
一种嵌合分子及其制备和应用
|
|
US20180353501A1
(en)
|
2017-06-09 |
2018-12-13 |
Arvinas, Inc. |
Modulators of proteolysis and associated methods of use
|
|
EP3641762B1
(en)
|
2017-06-20 |
2026-02-18 |
C4 Therapeutics, Inc. |
N/o-linked degrons and degronimers for protein degradation
|
|
CN109096395B
(zh)
|
2017-06-20 |
2022-06-24 |
华兰生物工程股份有限公司 |
阻断型cd47纳米抗体及其用途
|
|
GB201709866D0
(en)
|
2017-06-20 |
2017-08-02 |
Immunocore Ltd |
T cell receptors
|
|
PL3658589T3
(pl)
|
2017-07-26 |
2024-03-18 |
Forty Seven, Inc. |
Przeciwciała anty-sirp-alfa i powiązane sposoby
|
|
US11401329B2
(en)
|
2017-08-02 |
2022-08-02 |
Phanes Therapeutics, Inc. |
Anti-CD47 antibodies and uses thereof
|
|
JP7267280B2
(ja)
|
2017-08-08 |
2023-05-01 |
パイオニア イミュノセラピューティクス インコーポレイテッド |
Ｔｒｅｍ１を発現する骨髄細胞を無能化させるための組成物および方法
|
|
CN107446050A
(zh)
|
2017-08-11 |
2017-12-08 |
百奥泰生物科技(广州)有限公司 |
Trop2阳性疾病治疗的化合物及方法
|
|
EP4435008A2
(en)
|
2017-08-18 |
2024-09-25 |
Centessa Pharmaceuticals (UK) Limited |
Binding agents
|
|
TWI793151B
(zh)
|
2017-08-23 |
2023-02-21 |
瑞士商諾華公司 |
3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
|
|
CN109422811A
(zh)
|
2017-08-29 |
2019-03-05 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
|
CN108503708B
(zh)
|
2017-09-01 |
2021-07-30 |
北京智仁美博生物科技有限公司 |
抗人cd47抗体及其用途
|
|
CN109422726B
(zh)
|
2017-09-04 |
2022-10-28 |
华东理工大学 |
CD47/SIRPα的阻断剂及其应用
|
|
CN111315735B
(zh)
|
2017-09-04 |
2024-03-08 |
C4医药公司 |
二氢苯并咪唑酮
|
|
EP3679028A1
(en)
|
2017-09-04 |
2020-07-15 |
C4 Therapeutics, Inc. |
Dihydroquinolinones
|
|
EP3688012A4
(en)
|
2017-09-27 |
2021-06-30 |
Vividion Therapeutics, Inc. |
COMPOUNDS AND METHODS FOR MODULATING PROTEIN DEGRADATION
|
|
EP3676268A1
(en)
|
2017-10-20 |
2020-07-08 |
Dana-Farber Cancer Institute, Inc. |
Heterobifunctional compounds with improved specificityfor the bromodomain of brd4
|
|
WO2019084030A1
(en)
|
2017-10-24 |
2019-05-02 |
Genentech, Inc. |
(4-HYDROXYPYRROLIDIN-2-YL) -HYDROXAMATE COMPOUNDS AND METHODS OF USE
|
|
EP3700901A1
(en)
|
2017-10-24 |
2020-09-02 |
Genentech, Inc. |
(4-hydroxypyrrolidin-2-yl)-heterocyclic compounds and methods of use thereof
|
|
WO2019084538A1
(en)
|
2017-10-27 |
2019-05-02 |
Board Of Regents, The University Of Texas System |
TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF
|
|
US20220298254A1
(en)
|
2017-11-01 |
2022-09-22 |
Hummingbird Bioscience Holdings Pte. Ltd. |
Cd47 antigen-binding molecules
|
|
US11065231B2
(en)
|
2017-11-17 |
2021-07-20 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of interleukin-1 receptor- associated kinase 4 polypeptides
|
|
KR102436084B1
(ko)
|
2017-11-24 |
2022-08-25 |
주식회사 젬백스앤카엘 |
신규 펩티드 및 이를 포함한 조성물
|
|
TWI831759B
(zh)
|
2017-12-01 |
2024-02-11 |
美商思進公司 |
Cd47抗體及其用於治療癌症之用途
|
|
CN109879957B
(zh)
|
2017-12-06 |
2022-03-18 |
香雪生命科学技术（广东）有限公司 |
针对prame的高亲和力t细胞受体
|
|
MX2020006213A
(es)
|
2017-12-12 |
2020-09-14 |
Pionyr Immunotherapeutics Inc |
Anticuerpos anti-trem2 y metodos relacionados.
|
|
AU2019206438B2
(en)
|
2018-01-12 |
2023-12-07 |
Aurigene Oncology Limited |
1,2,4-oxadiazole compounds as inhibitors of CD47 signalling pathways
|
|
AU2019212674A1
(en)
|
2018-01-24 |
2020-09-03 |
Nanjing Legend Biotech Co., Ltd. |
Anti-CD47 antibodies that do not cause significant red blood cell agglutination
|
|
GB201802201D0
(en)
|
2018-02-09 |
2018-03-28 |
Ultrahuman Five Ltd |
Binding agents
|
|
KR102708681B1
(ko)
|
2018-02-13 |
2024-09-26 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
CN110144009B
(zh)
|
2018-02-14 |
2020-01-21 |
上海洛启生物医药技术有限公司 |
Cd47单域抗体及其用途
|
|
EP4424710A3
(en)
|
2018-02-26 |
2025-01-15 |
Medigene Immunotherapies GmbH |
Nyeso tcr
|
|
TWI823906B
(zh)
|
2018-03-09 |
2023-12-01 |
美商艾吉納斯公司 |
抗-cd73 抗體及其使用方法
|
|
WO2019175218A1
(en)
|
2018-03-13 |
2019-09-19 |
Ose Immunotherapeutics |
Use of anti-human sirpa v1 antibodies and method for producing anti-sirpa v1 antibodies
|
|
WO2019179366A1
(en)
|
2018-03-20 |
2019-09-26 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-cd47 antibodies
|
|
EP3768314A4
(en)
|
2018-03-21 |
2022-01-05 |
ALX Oncology Inc. |
ANTIBODIES AGAINST ALPHA SIGNAL REGULATING PROTEIN AND METHODS OF USE
|
|
CN110305212A
(zh)
|
2018-03-27 |
2019-10-08 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
|
GB201804860D0
(en)
|
2018-03-27 |
2018-05-09 |
Ultrahuman Two Ltd |
CD47 Binding agents
|
|
CN110386984B
(zh)
|
2018-04-17 |
2022-04-22 |
杭州尚健生物技术有限公司 |
结合cd47蛋白的融合蛋白及其应用
|
|
JP7469807B2
(ja)
|
2018-04-19 |
2024-04-17 |
ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム |
Ｍａｇｅ－ｂ２特異性を有するｔ細胞受容体およびその使用
|
|
CN110577597B
(zh)
|
2018-06-11 |
2021-10-22 |
康诺亚生物医药科技（成都）有限公司 |
一种阻断CD47和SIRPα相互作用的抗体
|
|
WO2019241732A1
(en)
|
2018-06-15 |
2019-12-19 |
Accurus Biosciences, Inc. |
Blocking antibodies against cd47 and methods of use thereof
|
|
WO2020009725A1
(en)
|
2018-07-05 |
2020-01-09 |
Trican Biotechnology Co., Ltd |
Human anti-cd47 antibodies and uses thereof
|
|
EP3821005A4
(en)
|
2018-07-09 |
2022-10-26 |
Genequantum Healthcare (Suzhou) Co., Ltd. |
AGAINST TROPHOBLAST ANTIGEN 2 (TROP2) SPECIFIC ANTIBODIES
|
|
CU20210002A7
(es)
|
2018-07-10 |
2021-08-06 |
Novartis Ag |
Derivados de 3-(5-hidroxi-1-oxoisoindolin-2-il)piperidina-2,6-diona y su uso en el tratamiento de trastornos dependientes de la proteína con dedos de zinc 2 de la familia ikaros (ikzf2)
|
|
KR102816742B1
(ko)
|
2018-07-10 |
2025-06-05 |
고쿠리츠다이가쿠호진 고베다이가쿠 |
항 SIRPα 항체
|
|
UA126421C2
(uk)
|
2018-07-13 |
2022-09-28 |
Гіліад Сайєнсіз, Інк. |
Інгібітори pd-1/pd-l1
|
|
WO2020019135A1
(zh)
|
2018-07-23 |
2020-01-30 |
中国科学院微生物研究所 |
一种抗cd47抗体及其应用
|
|
EP3836960A4
(en)
|
2018-08-13 |
2022-05-11 |
Arch Oncology, Inc. |
THERAPEUTIC CD47 ANTIBODIES
|
|
WO2020043188A1
(zh)
|
2018-08-31 |
2020-03-05 |
南京圣和药业股份有限公司 |
抗cd47抗体及其应用
|
|
CN113272435B
(zh)
|
2018-09-05 |
2025-11-14 |
加利福尼亚大学董事会 |
在多个主要组织相容性复合体分子上受限的ny-eso-1特异性t细胞受体的组合物
|
|
CN110950949B
(zh)
|
2018-09-26 |
2022-04-05 |
香雪生命科学技术（广东）有限公司 |
一种识别ssx2抗原的t细胞受体
|
|
TW202028237A
(zh)
|
2018-09-27 |
2020-08-01 |
美商西建公司 |
SIRPα結合蛋白及其使用方法
|
|
KR102716514B1
(ko)
|
2018-10-10 |
2024-10-15 |
주식회사 노벨티노빌리티 |
신규 항-c-KIT 항체
|
|
EA202191107A1
(ru)
|
2018-10-23 |
2021-09-17 |
Ридженерон Фармасьютикалз, Инк. |
T-клеточные рецепторы ny-eso-1 и способы их применения
|
|
PE20211655A1
(es)
|
2018-10-31 |
2021-08-24 |
Gilead Sciences Inc |
Compuestos de 6-azabencimidazol sustituidos como inhibidores de hpk1
|
|
WO2020092528A1
(en)
|
2018-10-31 |
2020-05-07 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
|
|
WO2020094670A1
(en)
|
2018-11-05 |
2020-05-14 |
Synaffix B.V. |
Antibody-conjugates for targeting of tumours expressing trop-2
|
|
WO2020117759A1
(en)
|
2018-12-03 |
2020-06-11 |
Dana-Farber Cancer Institute, Inc. |
Small molecule degraders of helios and methods of use
|
|
CA3124330A1
(en)
|
2018-12-21 |
2020-06-25 |
Daiichi Sankyo Company, Limited |
Combination of antibody-drug conjugate and kinase inhibitor
|
|
KR102940634B1
(ko)
|
2018-12-27 |
2026-03-17 |
시오노기세이야쿠가부시키가이샤 |
신규 항 ccr8 항체
|
|
IL288485B2
(en)
|
2019-05-29 |
2026-04-01 |
Daiichi Sankyo Co Ltd |
Anti-TROP2 antibody conjugates - a drug for use in cancer treatment
|
|
WO2020249063A1
(en)
|
2019-06-13 |
2020-12-17 |
Bio-Thera Solutions, Ltd. |
Methods for the treatment of trop2 positive diseases
|
|
WO2020257648A1
(en)
|
2019-06-20 |
2020-12-24 |
Fred Hutchinson Cancer Research Center |
Microlumenal targeting of cancer cells
|
|
AU2020301161B2
(en)
|
2019-06-25 |
2023-10-26 |
Gilead Sciences, Inc. |
FLT3L-Fc fusion proteins and methods of use
|
|
CA3148745A1
(en)
|
2019-08-29 |
2021-03-04 |
Xiaolun Wang |
Kras g12d inhibitors
|
|
US20210093730A1
(en)
|
2019-10-01 |
2021-04-01 |
Immunomedics, Inc. |
Biomarkers for antibody-drug conjugate monotherapy or combination therapy
|
|
KR20220103753A
(ko)
|
2019-11-19 |
2022-07-22 |
브리스톨-마이어스 스큅 컴퍼니 |
헬리오스 단백질의 억제제로서 유용한 화합물
|
|
EP4445902A3
(en)
|
2019-12-24 |
2024-12-18 |
Carna Biosciences, Inc. |
Diacylglycerol kinase modulating compounds
|
|
CN117964757A
(zh)
|
2020-02-14 |
2024-05-03 |
吉利德科学公司 |
与ccr8结合的抗体和融合蛋白及其用途
|
|
CN111534585A
(zh)
|
2020-03-23 |
2020-08-14 |
至本医疗科技（上海）有限公司 |
一种非小细胞肺癌（nsclc）患者免疫疗法预后的方法
|
|
TW202216771A
(zh)
|
2020-06-26 |
2022-05-01 |
德商拜耳廠股份有限公司 |
用於治療應用之ccr8抗體
|
|
CN112321715B
(zh)
|
2020-11-03 |
2022-05-10 |
博奥信生物技术（南京）有限公司 |
抗trop2纳米抗体及其制备方法和应用
|
|
WO2022188729A1
(en)
*
|
2021-03-07 |
2022-09-15 |
Jacobio Pharmaceuticals Co., Ltd. |
Fused ring derivatives useful as kras g12d inhibitors
|
|
CN117677624A
(zh)
*
|
2021-07-19 |
2024-03-08 |
上海艾力斯医药科技股份有限公司 |
新型吡啶并嘧啶衍生物
|
|
EP4373827A4
(en)
*
|
2021-07-23 |
2025-06-04 |
Suzhou Zanrong Pharma Limited |
KRAS G12D inhibitors and uses thereof
|
|
TW202315626A
(zh)
*
|
2021-08-31 |
2023-04-16 |
大陸商勁方醫藥科技(上海)有限公司 |
嘧啶并環類化合物及其製法和用途
|