|
US8236A
(en)
|
|
1851-07-22 |
|
Hanging cakriage-body |
|
US319A
(en)
|
|
1837-07-31 |
|
Improvement in machines for breaking and dressing hemp and flax |
|
US4434150A
(en)
|
1981-10-19 |
1984-02-28 |
Ortho Diagnostic Systems, Inc. |
Immunological reagents employing polymeric backbone possessing reactive functional groups
|
|
US4486414A
(en)
|
1983-03-21 |
1984-12-04 |
Arizona Board Of Reagents |
Dolastatins A and B cell growth inhibitory substances
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US4880935A
(en)
|
1986-07-11 |
1989-11-14 |
Icrf (Patents) Limited |
Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates
|
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
US4936824A
(en)
|
1987-05-15 |
1990-06-26 |
The Boc Group, Inc. |
Infant incubator with air curtain
|
|
US4880078A
(en)
|
1987-06-29 |
1989-11-14 |
Honda Giken Kogyo Kabushiki Kaisha |
Exhaust muffler
|
|
US4816444A
(en)
|
1987-07-10 |
1989-03-28 |
Arizona Board Of Regents, Arizona State University |
Cell growth inhibitory substance
|
|
FI102355B1
(fi)
|
1988-02-11 |
1998-11-30 |
Bristol Myers Squibb Co |
Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjugaattien valmistamiseksi
|
|
US5076973A
(en)
|
1988-10-24 |
1991-12-31 |
Arizona Board Of Regents |
Synthesis of dolastatin 3
|
|
WO1990005144A1
(en)
|
1988-11-11 |
1990-05-17 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
|
US4978744A
(en)
|
1989-01-27 |
1990-12-18 |
Arizona Board Of Regents |
Synthesis of dolastatin 10
|
|
JPH0684824B2
(ja)
|
1989-05-15 |
1994-10-26 |
清水建設株式会社 |
香り供給方法および香り供給装置
|
|
US4879278A
(en)
|
1989-05-16 |
1989-11-07 |
Arizona Board Of Regents |
Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
|
|
US4986988A
(en)
|
1989-05-18 |
1991-01-22 |
Arizona Board Of Regents |
Isolation and structural elucidation of the cytostatic linear depsipeptides dolastatin 13 and dehydrodolastatin 13
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5138036A
(en)
|
1989-11-13 |
1992-08-11 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Isolation and structural elucidation of the cytostatic cyclodepsipeptide dolastatin 14
|
|
US5124471A
(en)
|
1990-03-26 |
1992-06-23 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Bifunctional dtpa-type ligand
|
|
ATE221379T1
(de)
|
1991-05-01 |
2002-08-15 |
Jackson H M Found Military Med |
Verfahren zur behandlung infektiöser respiratorischer erkrankungen
|
|
US6287792B1
(en)
|
1991-06-17 |
2001-09-11 |
The Regents Of The University Of California |
Drug delivery of antisense oligonucleotides and peptides to tissues in vivo and to cells using avidin-biotin technology
|
|
US5622929A
(en)
|
1992-01-23 |
1997-04-22 |
Bristol-Myers Squibb Company |
Thioether conjugates
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
|
US6034065A
(en)
|
1992-12-03 |
2000-03-07 |
Arizona Board Of Regents |
Elucidation and synthesis of antineoplastic tetrapeptide phenethylamides of dolastatin 10
|
|
US5410024A
(en)
|
1993-01-21 |
1995-04-25 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide amides
|
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
|
WO1994016729A1
(en)
|
1993-01-28 |
1994-08-04 |
Neorx Corporation |
Targeted nitric oxide pathway or nitric oxide synthase modulation
|
|
US5934272A
(en)
|
1993-01-29 |
1999-08-10 |
Aradigm Corporation |
Device and method of creating aerosolized mist of respiratory drug
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
WO1995015770A1
(en)
|
1993-12-09 |
1995-06-15 |
Neorx Corporation |
Pretargeting methods and compounds
|
|
US5530097A
(en)
|
1994-08-01 |
1996-06-25 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory peptide amides
|
|
US5521284A
(en)
|
1994-08-01 |
1996-05-28 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide amides and esters
|
|
US5504191A
(en)
|
1994-08-01 |
1996-04-02 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide methyl esters
|
|
US5554725A
(en)
|
1994-09-14 |
1996-09-10 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Synthesis of dolastatin 15
|
|
US5599902A
(en)
|
1994-11-10 |
1997-02-04 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Cancer inhibitory peptides
|
|
US5663149A
(en)
|
1994-12-13 |
1997-09-02 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
|
|
US6019968A
(en)
|
1995-04-14 |
2000-02-01 |
Inhale Therapeutic Systems, Inc. |
Dispersible antibody compositions and methods for their preparation and use
|
|
DE69626849T2
(de)
|
1995-12-22 |
2003-12-24 |
Bristol-Myers Squibb Co., Princeton |
Verzweigte hydrazongruppen enthaltende kuppler
|
|
IT1282692B1
(it)
|
1996-02-27 |
1998-03-31 |
San Raffaele Centro Fond |
Citochine modificate per l'uso in terapia
|
|
DK0885002T3
(da)
|
1996-03-04 |
2011-08-22 |
Penn State Res Found |
Materialer og fremgangsmåder til forøgelse af cellulær internalisering
|
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
|
US5985309A
(en)
|
1996-05-24 |
1999-11-16 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
|
US5855913A
(en)
|
1997-01-16 |
1999-01-05 |
Massachusetts Instite Of Technology |
Particles incorporating surfactants for pulmonary drug delivery
|
|
ATE287257T1
(de)
|
1997-01-16 |
2005-02-15 |
Massachusetts Inst Technology |
Zubereitung von partikelhaltigen arzneimitteln zur inhalation
|
|
CA2279590A1
(en)
|
1997-02-13 |
1998-08-20 |
Bone Care International, Inc. |
Targeted therapeutic delivery of vitamin d compounds
|
|
CA2282504A1
(en)
|
1997-02-25 |
1998-08-27 |
Jun-Ping Xu |
Isolation and structural elucidation of the cytostatic linear and cyclo-depsipeptides dolastatin 16, dolastatin 17, and dolastatin 18
|
|
JPH11154024A
(ja)
|
1997-09-16 |
1999-06-08 |
Sumitomo Electric Ind Ltd |
負荷液圧の制御方法
|
|
AU9692498A
(en)
|
1997-10-10 |
1999-05-03 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Complex of biotinylated viral vector and ligand for targeted gene delivery
|
|
US6280955B1
(en)
|
1997-12-16 |
2001-08-28 |
Tularik Inc. |
Interleukin-1 receptor accessory proteins, nucleic acids and methods
|
|
PT1071700E
(pt)
|
1998-04-20 |
2010-04-23 |
Glycart Biotechnology Ag |
Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
|
|
AU747231B2
(en)
|
1998-06-24 |
2002-05-09 |
Alkermes, Inc. |
Large porous particles emitted from an inhaler
|
|
WO2000061739A1
(fr)
|
1999-04-09 |
2000-10-19 |
Kyowa Hakko Kogyo Co., Ltd. |
Methode de regulation de l'activite d'une molecule immunologiquement fonctionnelle
|
|
CN1189836C
(zh)
|
1999-07-31 |
2005-02-16 |
朴奎珍 |
使用数字音频和字幕数据的学习方法和装置
|
|
US6323315B1
(en)
|
1999-09-10 |
2001-11-27 |
Basf Aktiengesellschaft |
Dolastatin peptides
|
|
WO2001090198A1
(en)
|
2000-05-24 |
2001-11-29 |
Ludwig Institute For Cancer Research |
Multicomponent conjugates which bind to target molecules and stimulate cell lysis
|
|
ATE309385T1
(de)
|
2000-06-28 |
2005-11-15 |
Glycofi Inc |
Verfahren für die herstellung modifizierter glykoproteine
|
|
US7449308B2
(en)
|
2000-06-28 |
2008-11-11 |
Glycofi, Inc. |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
|
|
AU2013203432A1
(en)
|
2000-06-29 |
2013-05-02 |
Abbvie Inc. |
Dual specificity antibodies and methods of making and using
|
|
US20030026806A1
(en)
|
2000-10-27 |
2003-02-06 |
Amgen Inc. |
Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
US20030083263A1
(en)
|
2001-04-30 |
2003-05-01 |
Svetlana Doronina |
Pentapeptide compounds and uses related thereto
|
|
US6441163B1
(en)
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
US20030138803A1
(en)
|
2001-07-27 |
2003-07-24 |
Brooksbank Robert Alan |
Identification and use of molecules implicated in pain
|
|
PL374118A1
(en)
|
2001-08-07 |
2005-10-03 |
Immunex Corporation |
Interleukin-1 receptors in the treatment of diseases
|
|
EP1432444A4
(en)
|
2001-08-17 |
2005-11-02 |
Lilly Co Eli |
ANTI-BETA ANTIBODIES
|
|
NZ532526A
(en)
|
2001-10-25 |
2007-01-26 |
Genentech Inc |
Compositions comprising a glycoprotein having a Fc region
|
|
EP1497466A4
(en)
|
2002-05-01 |
2007-11-14 |
Trellis Bioscience Inc |
BINARY OR POLYNARY TARGETING AND USES THEREOF
|
|
JP4741838B2
(ja)
|
2002-07-31 |
2011-08-10 |
シアトル ジェネティクス,インコーポレーテッド |
癌、自己免疫疾患または感染症を治療するための薬物結合体およびその使用
|
|
ATE499116T1
(de)
|
2002-08-16 |
2011-03-15 |
Immunogen Inc |
Vernetzer mit hoher reaktivität und löslichkeit und ihre verwendung bei der herstellung von konjugaten für die gezielte abgabe von kleinmolekularen arzneimitteln
|
|
US7438910B2
(en)
|
2002-09-06 |
2008-10-21 |
Amgen Inc. |
Therapeutic human anti-IL1-R1 monoclonal antibody
|
|
US7388079B2
(en)
|
2002-11-27 |
2008-06-17 |
The Regents Of The University Of California |
Delivery of pharmaceutical agents via the human insulin receptor
|
|
AR045614A1
(es)
|
2003-09-10 |
2005-11-02 |
Hoffmann La Roche |
Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
|
|
US20050129685A1
(en)
|
2003-09-18 |
2005-06-16 |
Jingtai Cao |
Use of IL-1 blockers to prevent corneal inflammation and neovascularization
|
|
CN104998273A
(zh)
|
2003-11-06 |
2015-10-28 |
西雅图基因公司 |
能够与配体偶联的单甲基缬氨酸化合物
|
|
EP1718323B1
(en)
|
2004-02-20 |
2011-12-07 |
The Trustees of The University of Pennsylvania |
Binding peptidomimetics and uses of the same
|
|
US20050226882A1
(en)
|
2004-04-08 |
2005-10-13 |
Awdalla Essam T |
Method and multicomponent conjugates for treating cancer
|
|
JP2007535317A
(ja)
|
2004-04-15 |
2007-12-06 |
グライコフィ, インコーポレイテッド |
下等真核生物におけるガラクトシル化された糖タンパク質の産生
|
|
EP1751175B1
(en)
|
2004-05-05 |
2012-07-25 |
VALORISATION-RECHERCHE, Société en Commandite |
Interleukin-1 receptor antagonists, compositions, and methods of treatment
|
|
US8618054B2
(en)
|
2004-05-05 |
2013-12-31 |
Valorisation-Rechereche Société en Commandite |
Interleukin-1 receptor antagonists, compositions, and methods of treatment
|
|
US7691962B2
(en)
|
2004-05-19 |
2010-04-06 |
Medarex, Inc. |
Chemical linkers and conjugates thereof
|
|
CA2567520A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Maytansinoid-antibody conjugates
|
|
GB0419124D0
(en)
|
2004-08-27 |
2004-09-29 |
Proteome Sciences Plc |
Methods and compositions relating to Alzheimer's disease
|
|
EP1695717A1
(en)
|
2005-02-23 |
2006-08-30 |
Ludwig-Maximilians-Universität |
Transport of nano-and macromolecular structures into cytoplasm and nucleus of cells
|
|
AU2014203217B2
(en)
|
2005-08-19 |
2017-03-30 |
Abbvie Inc. |
Dual variable domain immunoglobin and uses thereof
|
|
EP1948220A2
(en)
|
2005-10-21 |
2008-07-30 |
Amgen Inc. |
Methods of decreasing vascular calcification using il-1 inhibitors
|
|
CA2635472A1
(en)
|
2006-02-22 |
2007-08-30 |
University Of Zurich |
Soluble receptors and methods for treating autoimmune or demyelinating diseases
|
|
CA2690973A1
(en)
|
2006-06-23 |
2007-12-27 |
Paul M. Simon |
Targeted immune conjugates
|
|
US7560530B1
(en)
|
2006-07-20 |
2009-07-14 |
Schering Corporation |
IL-33 receptor
|
|
CL2007002567A1
(es)
*
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
US7767206B2
(en)
*
|
2006-10-02 |
2010-08-03 |
Amgen Inc. |
Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
|
|
US7632490B2
(en)
|
2006-10-20 |
2009-12-15 |
Regeneron Pharmaceuticals, Inc. |
Use of IL-1 antagonists to treat gout
|
|
US7598028B2
(en)
|
2006-11-28 |
2009-10-06 |
The Regents Of The University Of Michigan |
Compositions and methods for detecting and treating prostate disorders
|
|
CN101594908A
(zh)
|
2007-01-03 |
2009-12-02 |
加利福尼亚大学董事会 |
在体胞内转染用于治疗大动物和人的关节炎和其他整形外科疾病的基因、siRNA、shRNA载体以及其他生物医学诊断和治疗药物的装置和方法
|
|
NZ593450A
(en)
|
2007-02-02 |
2012-08-31 |
Baylor Res Inst |
Vaccines based on targeting antigen to dcir expressed on antigen-presenting cells
|
|
TWI422594B
(zh)
|
2007-02-02 |
2014-01-11 |
Baylor Res Inst |
經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑
|
|
SI2716301T1
(sl)
|
2007-02-16 |
2017-07-31 |
Merrimack Pharmaceuticals, Inc. |
Protitelesa proti ErbB3 in uporaba le-teh
|
|
EP3489260B1
(en)
|
2007-02-23 |
2020-12-02 |
Baylor Research Institute |
Activation of human antigen-presenting cells through dendritic cell lectin-like oxidized ldl receptor-1 (lox-1)
|
|
JP2010519313A
(ja)
|
2007-02-23 |
2010-06-03 |
ベイラー リサーチ インスティテュート |
Clec−6を介したヒト抗原提示細胞の活性化
|
|
JP2010526528A
(ja)
|
2007-05-03 |
2010-08-05 |
メディツィニーチェ ウニベルシタット インスブルック |
補体因子h由来ショートコンセンサスリピート−抗体構築物
|
|
JP5894364B2
(ja)
|
2007-08-16 |
2016-03-30 |
ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド |
眼および付属器組織の炎症を処置するための治療組成物
|
|
JP2011515497A
(ja)
|
2008-03-26 |
2011-05-19 |
セレラント セラピューティクス インコーポレイテッド |
骨髄性血液学的増殖性疾患と関連する免疫グロブリンおよび/またはToll様受容体タンパク質ならびにその使用
|
|
CN101348526B
(zh)
|
2008-08-29 |
2011-08-17 |
浙江大学 |
一种抗白细胞介素-8抗体
|
|
US8298533B2
(en)
|
2008-11-07 |
2012-10-30 |
Medimmune Limited |
Antibodies to IL-1R1
|
|
EP2385839B1
(en)
|
2009-01-09 |
2014-11-26 |
The Schepens Eye Research Institute, Inc. |
Therapeutic compositions for treatment of corneal disorders
|
|
CA2750818A1
(en)
|
2009-01-27 |
2010-08-05 |
Proteogenix, Inc. |
Biomarkers for detection of neonatal sepsis in biological fluid
|
|
CA2753388C
(en)
|
2009-03-23 |
2016-11-29 |
Quark Pharmaceuticals, Inc. |
Endo180 antibody to treat cancer and fibrotic disease
|
|
WO2010127275A1
(en)
|
2009-05-01 |
2010-11-04 |
Oregon Health & Scince University |
Method of expanding human hepatocytes in vivo
|
|
DE102009026075A1
(de)
|
2009-06-30 |
2011-01-05 |
Röhm Gmbh |
Bohrvorrichtung
|
|
WO2011017294A1
(en)
|
2009-08-07 |
2011-02-10 |
Schering Corporation |
Human anti-rankl antibodies
|
|
GB2472856B
(en)
|
2009-08-21 |
2012-07-11 |
Cantargia Ab |
IL1-RAP modulators and uses thereof
|
|
US20120263709A1
(en)
|
2009-09-10 |
2012-10-18 |
Schering Corporation |
Use of il-33 antagonists to treat fibrotic diseases
|
|
MX2012003396A
(es)
|
2009-09-16 |
2012-04-10 |
Genentech Inc |
Complejos de proteina conteniendo helice super-enrollada y/o enlazador tether y usos de los mismos.
|
|
US20110076232A1
(en)
|
2009-09-29 |
2011-03-31 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
|
WO2011057216A1
(en)
|
2009-11-06 |
2011-05-12 |
The Pennsylvania State Research Foundation |
Bioconjugation of calcium phosphosilicate nanoparticles for selective targeting of cells in vivo
|
|
GB0919751D0
(en)
|
2009-11-11 |
2009-12-30 |
King S College Hospital Nhs Fo |
Conjugate molecule
|
|
US20130195868A1
(en)
|
2010-06-24 |
2013-08-01 |
Eleven Biotherapeutics, Inc. |
Treating surface of the eye disorders
|
|
WO2012027494A1
(en)
|
2010-08-24 |
2012-03-01 |
Regents Of The University Of Minnesota |
Bispecific targeting reagents
|
|
UY33826A
(es)
|
2010-12-22 |
2012-07-31 |
Abbott Lab |
Proteínas de unión con dominios trivariables y sus usos
|
|
WO2012088302A2
(en)
|
2010-12-22 |
2012-06-28 |
Abbott Laboratories |
Half immunoglobulin binding proteins and uses thereof
|
|
EP3508498A1
(en)
|
2011-01-19 |
2019-07-10 |
Cantargia AB |
Novel agents and uses thereof
|
|
US20140030735A1
(en)
|
2011-03-07 |
2014-01-30 |
Temple University - Of The Commonwealth System Of Higher Education |
Biomarkers of chronic obstructive pulmonary disease
|
|
AU2012242666A1
(en)
|
2011-04-15 |
2013-11-28 |
Merck Patent Gmbh |
Anti- IL-1R1 inhibitors for use in cancer
|
|
ES2669310T3
(es)
|
2011-04-20 |
2018-05-24 |
Medimmune, Llc |
Anticuerpos y otras moléculas que se unen con B7-H1 y PD-1
|
|
CN103608030A
(zh)
|
2011-06-21 |
2014-02-26 |
昂科发克特公司 |
用于治疗和诊断癌症的组合物和方法
|
|
WO2013023015A2
(en)
|
2011-08-11 |
2013-02-14 |
Albert Einstein College Of Medicine Of Yeshiva University |
Targets for diagnosis, prognosis and therapy of acute myeloid leukemia and myelodysplastic syndromes
|
|
US9534058B2
(en)
|
2012-02-08 |
2017-01-03 |
Abbvie Stemcentrx Llc |
Anti-CD324 monoclonal antibodies and uses thereof
|
|
US8975398B2
(en)
|
2012-05-11 |
2015-03-10 |
Abbvie Inc. |
NAMPT inhibitors
|
|
US20150315279A1
(en)
|
2012-12-21 |
2015-11-05 |
Cellerant Therapeutics, Inc. |
Antibodies that bind membrane-bound il1rap
|
|
WO2014135655A1
(en)
|
2013-03-06 |
2014-09-12 |
Institut Curie |
Compositions and methods for treating muscle-invasive bladder cancer
|
|
JO3532B1
(ar)
|
2013-03-13 |
2020-07-05 |
Regeneron Pharma |
الأجسام المضادة لمضاد انترلوكين-33 واستعمالاتها
|
|
WO2014142591A1
(ko)
|
2013-03-13 |
2014-09-18 |
(주) 아이벤트러스 |
소수성 상호작용 부위내에 전기적 상호작용이 도입된 단백질 및 이의 제조방법
|
|
AR095196A1
(es)
|
2013-03-15 |
2015-09-30 |
Regeneron Pharma |
Medio de cultivo celular libre de suero
|
|
WO2014144292A2
(en)
|
2013-03-15 |
2014-09-18 |
Sanofi Pasteur Biologics , Llc |
Antibodies against clostridium difficile toxins and methods of using the same
|
|
US9637535B2
(en)
|
2013-03-15 |
2017-05-02 |
Regeneron Pharmaceuticals, Inc. |
IL-33 antagonists and uses thereof
|
|
CA2911547A1
(en)
|
2013-05-31 |
2014-12-04 |
Regeneron Pharmaceuticals, Inc. |
Methods of using il-1 antagonists to treat alzheimer's disease
|
|
CN105612180B
(zh)
|
2013-07-19 |
2019-11-12 |
弗拉芒区生物技术研究所 |
经靶向修饰的il-1家族成员
|
|
GB201403875D0
(en)
|
2014-03-05 |
2014-04-16 |
Cantargia Ab |
Novel antibodies and uses thereof
|
|
NO2785538T3
(enExample)
|
2014-05-07 |
2018-08-04 |
|
|
|
WO2016004389A2
(en)
|
2014-07-03 |
2016-01-07 |
Abbvie Inc. |
Monovalent binding proteins
|
|
GB201413913D0
(en)
*
|
2014-08-06 |
2014-09-17 |
Cantargia Ab |
Novel antibodies and uses thereof
|
|
WO2016028699A2
(en)
|
2014-08-18 |
2016-02-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Biomarkers for diagnosis and management of neuro-immunological diseases
|
|
JP2016044126A
(ja)
|
2014-08-19 |
2016-04-04 |
国立大学法人埼玉大学 |
次世代型フラグメント抗体作製用dnaライブラリの作製方法、その方法を用いて作製されたライブラリ、及び次世代型フラグメント抗体
|
|
US20160168640A1
(en)
|
2014-11-10 |
2016-06-16 |
Genentech, Inc. |
Therapeutic and diagnostic methods for il-33-mediated disorders
|
|
CN107074942A
(zh)
|
2014-11-10 |
2017-08-18 |
豪夫迈·罗氏有限公司 |
抗‑IL‑1β抗体和使用方法
|
|
MX2017006094A
(es)
|
2014-11-10 |
2017-07-19 |
Genentech Inc |
Anticuerpos anti-interleucina-33 y sus usos.
|
|
DK3221356T3
(da)
|
2014-11-20 |
2020-11-02 |
Hoffmann La Roche |
T-celleaktiverende, bispecifikke, antigenbindende molekyler mod folr1 og cd3
|
|
US11137397B2
(en)
|
2014-11-24 |
2021-10-05 |
Albert Einstein College Of Medicine |
Peptides for blocking IL1RAP protein-protein interaction and uses thereof for treatment of disease
|
|
JP6519913B2
(ja)
|
2015-02-05 |
2019-05-29 |
国立大学法人名古屋大学 |
IgE結合性エピトープペプチドの利用
|
|
US9504694B2
(en)
|
2015-03-19 |
2016-11-29 |
Cellerant Therapeutics, Inc. |
Isoquinolidinobenzodiazepines
|
|
TWI735433B
(zh)
|
2015-03-27 |
2021-08-11 |
美商再生元醫藥公司 |
偵測生物污染物之組成物及方法
|
|
SMT202100086T1
(it)
|
2015-03-31 |
2021-03-15 |
Medimmune Ltd |
Una nuova forma di il33, forme mutate di il33, anticorpi, saggi e metodi per usare gli stessi
|
|
WO2016179319A1
(en)
|
2015-05-04 |
2016-11-10 |
Cellerant Therapeutics, Inc. |
Chimeric antigen receptors with ctla4 signal transduction domains
|
|
CA2985203A1
(en)
|
2015-05-08 |
2016-11-17 |
President And Fellows Of Harvard College |
Targeted selection of patients for treatment with cortistatin derivatives
|
|
CA2990305A1
(en)
|
2015-06-26 |
2016-12-29 |
Mab Discovery Gmbh |
Monoclonal anti-il-1racp antibodies
|
|
CN108025092A
(zh)
|
2015-07-16 |
2018-05-11 |
塞勒兰特治疗公司 |
经半胱氨酸取代的免疫球蛋白
|
|
TWI717375B
(zh)
*
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
TW202440903A
(zh)
|
2015-08-04 |
2024-10-16 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法(一)
|
|
MA50638A
(fr)
|
2015-10-06 |
2020-08-05 |
Regeneron Pharma |
Biomarqueurs associés aux maladies médiées par l'interleukine-33 (il-33) et leurs utilisations
|
|
BR112018008908A2
(pt)
*
|
2015-11-02 |
2018-11-27 |
Janssen Pharmaceutica Nv |
anticorpos anti-il1rap, moléculas de ligação ao antígeno biespecíficas que se ligam il1rap e cd3, e seus usos
|
|
CA3004743A1
(en)
|
2015-11-24 |
2017-06-01 |
Cellerant Therapeutics, Inc. |
Humanized anti-cll-1 antibodies
|
|
EP3394038A4
(en)
|
2015-12-23 |
2019-08-21 |
President and Fellows of Harvard College |
TARGETED SELECTION OF PATIENTS FOR TREATMENT WITH SPECIFIC CORTISTATINE DERIVATIVES
|
|
AU2017257330A1
(en)
|
2016-04-27 |
2018-10-18 |
Pfizer Inc. |
Anti-IL-33 antibodies, compositions, methods and uses thereof
|
|
EP3241845A1
(en)
|
2016-05-06 |
2017-11-08 |
MAB Discovery GmbH |
Humanized anti-il-1r3 antibodies
|
|
CN106831998B
(zh)
|
2016-06-22 |
2020-09-15 |
徐州医科大学 |
一种人il1rap特异性car及其应用
|
|
JP6848241B2
(ja)
|
2016-07-25 |
2021-03-24 |
東ソー株式会社 |
Fc結合性タンパク質を用いたIgG1の精製方法
|
|
US20190225682A1
(en)
|
2016-09-02 |
2019-07-25 |
180 Therapeutics Lp |
Method of treating localized fibrotic disorders using an il-33/tnf bispecific antibody
|
|
WO2018053552A2
(en)
|
2016-09-19 |
2018-03-22 |
Cellerant Therapeutics, Inc. |
Isoquinolidinobenzodiazepines
|
|
WO2018071455A1
(en)
|
2016-10-10 |
2018-04-19 |
Cellerant Therapeutics, Inc. |
Isoquinolidinobenzodiazepine (iqb)-1(chloromethyl)-2,3-dihydro-1h-benzo[e]indole (cbi) dimers
|
|
US10222376B2
(en)
|
2016-11-03 |
2019-03-05 |
The Charlotte-Mecklenburg Hospital Authority |
Methods and compositions for identifying leukemic stem cells
|
|
TWI857389B
(zh)
|
2016-12-01 |
2024-10-01 |
美商再生元醫藥公司 |
治療發炎症狀的方法
|
|
WO2018112256A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with an il-1 inhibitor
|
|
CA3046975A1
(en)
|
2016-12-15 |
2018-06-21 |
Progenity, Inc. |
Ingestible device and associated methods
|
|
TWI778018B
(zh)
|
2017-02-10 |
2022-09-21 |
美商建南德克公司 |
抗類胰蛋白酶抗體、其組合物及其用途
|
|
EP3957752B1
(en)
|
2017-04-13 |
2025-08-20 |
Regeneron Pharmaceuticals, Inc. |
Treatment and inhibition of inflammatory lung diseases in patients having risk alleles in the genes encoding il33 and il1rl1
|
|
EP3401332A1
(en)
|
2017-05-08 |
2018-11-14 |
MAB Discovery GmbH |
Anti-il-1r3 antibodies for use in inflammatory conditions
|
|
KR102116178B1
(ko)
|
2017-05-10 |
2020-05-27 |
서울대학교산학협력단 |
간암 고위험군의 간암 발병 모니터링 또는 진단용 바이오마커 및 그 용도
|
|
US11149094B2
(en)
|
2017-06-05 |
2021-10-19 |
Janssen Biotech, Inc. |
Engineered multispecific antibodies and other multimeric proteins with asymmetrical CH2-CH3 region mutations
|
|
CN118994394A
(zh)
|
2017-06-12 |
2024-11-22 |
蓝鳍生物医药公司 |
抗-il1rap抗体和抗体药物缀合物
|
|
AU2018298039B2
(en)
|
2017-07-06 |
2023-02-02 |
Regeneron Pharmaceuticals, Inc. |
Cell culture process for making a glycoprotein
|
|
WO2019024979A1
(en)
|
2017-07-31 |
2019-02-07 |
Institute For Research In Biomedicine |
FUNCTIONAL DOMAIN ANTIBODIES IN THE ELBOW REGION
|
|
KR20200038490A
(ko)
|
2017-08-01 |
2020-04-13 |
시티 오브 호프 |
항-il1rap 항체
|
|
EP3687456B1
(en)
|
2017-09-25 |
2024-02-07 |
ECM Diagnostics, Inc. |
Methods for treating degenerative disc disease and chronic lower back pain with a combination of an antibiotic and an il-1beta inhibitor
|
|
WO2019099993A1
(en)
|
2017-11-17 |
2019-05-23 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for alleviating cytokine release syndrome
|
|
EP3489259A1
(en)
|
2017-11-23 |
2019-05-29 |
Etablissement Français du Sang |
Anti-il-1rap-car-t cells and their use
|
|
GB201720077D0
(en)
|
2017-12-01 |
2018-01-17 |
Univ Oxford Innovation Ltd |
Leukaemic stem cell
|
|
GB201800649D0
(en)
|
2018-01-16 |
2018-02-28 |
Argenx Bvba |
CD70 Combination Therapy
|
|
WO2019157358A1
(en)
|
2018-02-09 |
2019-08-15 |
Genentech, Inc. |
Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases
|
|
GB201802307D0
(en)
|
2018-02-13 |
2018-03-28 |
Vib Vzw |
CD36 antagonists for use in melanoma treatment
|
|
WO2019158579A1
(en)
|
2018-02-13 |
2019-08-22 |
Vib Vzw |
Targeting minimal residual disease in cancer with rxr antagonists
|
|
JP7530299B2
(ja)
|
2018-05-24 |
2024-08-07 |
ヤンセン バイオテツク,インコーポレーテツド |
抗cd3抗体及びその使用
|
|
WO2019230866A1
(en)
|
2018-05-30 |
2019-12-05 |
Chugai Seiyaku Kabushiki Kaisha |
Polypeptide comprising il-1r1 binding domain and carrying moiety
|
|
KR20190140756A
(ko)
|
2018-06-12 |
2019-12-20 |
주식회사 노보셀바이오 |
자연 살상 세포에 결합하는 이중특이적 항체 및 이의 용도
|