|
CH653021A5
(fr)
|
1981-04-24 |
1985-12-13 |
Delalande Sa |
Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant.
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
DE3883899T3
(de)
|
1987-03-18 |
1999-04-22 |
Sb2, Inc., Danville, Calif. |
Geänderte antikörper.
|
|
WO1990014844A2
(en)
|
1989-06-06 |
1990-12-13 |
Neorx Corporation |
Sugars as cleavable linkers for the delivery and release of agents in native form
|
|
US5650150A
(en)
|
1990-11-09 |
1997-07-22 |
Gillies; Stephen D. |
Recombinant antibody cytokine fusion proteins
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
ES2237750T3
(es)
*
|
1993-12-09 |
2005-08-01 |
Centro De Inmunologia Molecular |
Vacuna que comprende factor de crecimiento epidermico autologo humano y su uso.
|
|
JP4101302B2
(ja)
|
1997-01-09 |
2008-06-18 |
テルモ株式会社 |
新規アミド誘導体および合成中間体
|
|
ZA9811162B
(en)
*
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
|
US20090208418A1
(en)
*
|
2005-04-29 |
2009-08-20 |
Innexus Biotechnology Internaltional Ltd. |
Superantibody synthesis and use in detection, prevention and treatment of disease
|
|
US20020155108A1
(en)
|
1998-05-04 |
2002-10-24 |
Biocrystal, Ltd. |
Method for ex vivo loading of antigen presenting cells with antigen, and a vaccine comprising the loaded cells
|
|
FI107193B
(fi)
|
1999-06-03 |
2001-06-15 |
Rouvari Oy R |
Mittausanturi
|
|
SE9902036L
(sv)
|
1999-06-03 |
2000-07-31 |
Jan Folke Wallenius |
Förfarande och anordning för att under färd bestämma friktionen mellan vägbanan och ett fordons hjul
|
|
AU4306199A
(en)
|
1999-06-04 |
2000-12-28 |
Yun Fen Chin |
Apparatus and method for testing an impervious surface
|
|
US6541485B1
(en)
|
1999-06-10 |
2003-04-01 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
|
US6451810B1
(en)
|
1999-06-10 |
2002-09-17 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
|
US6331539B1
(en)
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
US6756382B2
(en)
|
1999-06-10 |
2004-06-29 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
|
US6573273B1
(en)
|
1999-06-10 |
2003-06-03 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
|
CA2399940A1
(en)
|
2000-04-13 |
2001-10-25 |
The Rockefeller University |
Enhancement of antibody-mediated immune responses
|
|
JP2003535907A
(ja)
|
2000-06-22 |
2003-12-02 |
ユニバーシティ オブ アイオワ リサーチ ファウンデーション |
抗体誘導性細胞溶解を促進し、そして癌を処置するための方法
|
|
EP1322326A4
(en)
*
|
2000-07-31 |
2005-08-17 |
Univ Yale |
VACCINES DIRECTED TO THE INNE IMMUNE SYSTEM
|
|
EP1427813A2
(en)
|
2000-10-24 |
2004-06-16 |
Immunex Corporation |
Method for dendritic cells-based immunotherapy of tumors using combination therapy
|
|
AU2002232498B2
(en)
|
2000-12-08 |
2006-05-04 |
3M Innovative Properties Company |
Screening method for identifying compounds that selectively induce interferon alpha
|
|
US20060142202A1
(en)
|
2000-12-08 |
2006-06-29 |
3M Innovative Properties Company |
Compositions and methods for targeted delivery of immune response modifiers
|
|
EP1719511B1
(en)
|
2001-11-16 |
2008-12-10 |
3M Innovative Properties Company |
N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide, a pharmaceutical composition comprising the same and use thereof
|
|
AU2002363954B2
(en)
|
2001-11-29 |
2008-04-03 |
3M Innovative Properties Company |
Pharmaceutical formulations comprising an immune response modifier
|
|
US6677349B1
(en)
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
HUE054986T2
(hu)
|
2002-03-01 |
2021-10-28 |
Immunomedics Inc |
Humanizált RS7 ellenanyagokat tartalmazó immunkonjugátum
|
|
ES2355819T3
(es)
|
2002-08-15 |
2011-03-31 |
3M Innovative Properties Company |
Composiciones inmunoestimuladoras y métodos para estimular una respuesta inmune.
|
|
US20040101909A1
(en)
|
2002-08-20 |
2004-05-27 |
Hema-Quebec, 2535 Boul. Laurier, Ste-Foy, Quebec, Canada G1V 4M3 |
Purification of polyreactive autoantibodies and uses thereof
|
|
US6924154B2
(en)
|
2002-08-20 |
2005-08-02 |
Quest Diagnostics Investments Incorporated |
Hydrophilic chemilumescent acridinium labeling reagents
|
|
JP2006503068A
(ja)
|
2002-09-26 |
2006-01-26 |
スリーエム イノベイティブ プロパティズ カンパニー |
1h−イミダゾダイマー
|
|
AU2003287316A1
(en)
|
2002-12-11 |
2004-06-30 |
3M Innovative Properties Company |
Assays relating to toll-like receptor activity
|
|
WO2004053057A2
(en)
|
2002-12-11 |
2004-06-24 |
3M Innovative Properties Company |
Gene expression systems and recombinant cell lines
|
|
CA2510375A1
(en)
|
2002-12-20 |
2004-07-15 |
3M Innovative Properties Company |
Aryl / hetaryl substituted imidazoquinolines
|
|
EP1578419A4
(en)
|
2002-12-30 |
2008-11-12 |
3M Innovative Properties Co |
IMMUNOSTIMULATING COMBINATIONS
|
|
US7375180B2
(en)
|
2003-02-13 |
2008-05-20 |
3M Innovative Properties Company |
Methods and compositions related to IRM compounds and Toll-like receptor 8
|
|
WO2004075865A2
(en)
|
2003-02-27 |
2004-09-10 |
3M Innovative Properties Company |
Selective modulation of tlr-mediated biological activity
|
|
JP2006523452A
(ja)
|
2003-03-25 |
2006-10-19 |
スリーエム イノベイティブ プロパティズ カンパニー |
共通のToll様受容体を通じて媒介される細胞活性の選択的活性化
|
|
US20040265351A1
(en)
|
2003-04-10 |
2004-12-30 |
Miller Richard L. |
Methods and compositions for enhancing immune response
|
|
EP1617872A4
(en)
|
2003-04-10 |
2011-09-07 |
3M Innovative Properties Co |
METHODS AND COMPOSITIONS FOR ENHANCING AN IMMUNE RESPONSE
|
|
WO2004091500A2
(en)
|
2003-04-10 |
2004-10-28 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds
|
|
US20040214851A1
(en)
|
2003-04-28 |
2004-10-28 |
3M Innovative Properties Company |
Compositions and methods for induction of opioid receptors
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
MY157827A
(en)
|
2003-06-27 |
2016-07-29 |
3M Innovative Properties Co |
Sulfonamide substituted imidazoquinolines
|
|
CN1852711A
(zh)
|
2003-08-05 |
2006-10-25 |
3M创新有限公司 |
使用免疫响应调节化合物的传染病预防
|
|
PL1653959T3
(pl)
|
2003-08-14 |
2015-10-30 |
3M Innovative Properties Co |
Modyfikatory odpowiedzi immunologicznej modyfikowane lipidami
|
|
US8198020B2
(en)
|
2003-08-22 |
2012-06-12 |
Potentia Pharmaceuticals, Inc. |
Compositions and methods for enhancing phagocytosis or phagocyte activity
|
|
RU2006105101A
(ru)
|
2003-08-27 |
2007-10-10 |
3М Инновейтив Пропертиз Компани (US) |
Арилокси и арилалкиленокси замещенные имидазохинолины
|
|
US20150071948A1
(en)
|
2003-09-26 |
2015-03-12 |
Gregory Alan Lazar |
Novel immunoglobulin variants
|
|
US8277810B2
(en)
|
2003-11-04 |
2012-10-02 |
Novartis Vaccines & Diagnostics, Inc. |
Antagonist anti-CD40 antibodies
|
|
WO2005051324A2
(en)
|
2003-11-25 |
2005-06-09 |
3M Innovative Properties Company |
Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
US20050158325A1
(en)
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Immunomodulatory combinations
|
|
US20060018911A1
(en)
|
2004-01-12 |
2006-01-26 |
Dana Ault-Riche |
Design of therapeutics and therapeutics
|
|
TW200612932A
(en)
|
2004-03-24 |
2006-05-01 |
3M Innovative Properties Co |
Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
|
WO2005110013A2
(en)
|
2004-04-09 |
2005-11-24 |
3M Innovative Properties Company |
Methods, compositions, and preparations for delivery of immune response modifiers
|
|
CA2565827A1
(en)
|
2004-05-05 |
2005-12-15 |
Merrimack Pharmaceuticals, Inc. |
Bispecific binding agents for modulating biological activity
|
|
WO2005123080A2
(en)
|
2004-06-15 |
2005-12-29 |
3M Innovative Properties Company |
Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
|
AU2005283085B2
(en)
|
2004-06-18 |
2012-06-21 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
BRPI0516284A
(pt)
|
2004-09-23 |
2008-09-02 |
Genentech Inc |
anticorpo construìdo com cisteìna, método de selecionar anticorpos, compostos conjugados de droga-anticorpo, composição farmacêutica, método para matar ou inibir a proliferação de células de tumor, métodos de inibir a proliferação celular e o crescimento de células de tumor, artigo manufaturado e método para produzir um composto
|
|
US20060135459A1
(en)
|
2004-11-09 |
2006-06-22 |
Epstein Alan L |
Targeted innate immunity
|
|
US8435800B2
(en)
|
2004-11-22 |
2013-05-07 |
Biosight Ltd. |
Activated labeling reagents and methods for preparing and using the same
|
|
EP1835935A4
(en)
|
2004-12-30 |
2009-06-17 |
Univ Rockefeller |
COMPOSITIONS AND METHODS FOR ENHANCING THE MATURATION AND FUNCTION OF DENDRITIC CELLS
|
|
CA2592904C
(en)
|
2004-12-30 |
2015-04-07 |
3M Innovative Properties Company |
Chiral fused [1,2]imidazo[4,5-c] ring compounds
|
|
EP1844201B1
(en)
|
2005-02-04 |
2016-08-24 |
3M Innovative Properties Company |
Aqueous gel formulations containing immune response modifiers
|
|
AU2006216997A1
(en)
|
2005-02-11 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Substituted imidazoquinolines and imidazonaphthyridines
|
|
CN101600475A
(zh)
|
2005-07-27 |
2009-12-09 |
佛罗里达大学研究基金会有限公司 |
修正蛋白质错误折叠的小型化合物及其使用
|
|
US8354249B2
(en)
|
2005-08-11 |
2013-01-15 |
Omrix Biopharmaceuticals Ltd. |
Intravenous immunoglobulin composition
|
|
CN101304748A
(zh)
|
2005-08-22 |
2008-11-12 |
加利福尼亚大学董事会 |
Tlr激动剂
|
|
US7700321B2
(en)
|
2005-10-21 |
2010-04-20 |
Genzyme Corporation |
Antibody-based therapeutics with enhanced ADCC activity
|
|
EP1957099B1
(en)
|
2005-11-07 |
2015-03-25 |
The Rockefeller University |
Reagents, methods and systems for selecting a cytotoxic antibody or variant thereof
|
|
EP3085373A1
(en)
|
2006-02-22 |
2016-10-26 |
3M Innovative Properties Company |
Immune response modifier conjugates
|
|
WO2007103048A2
(en)
|
2006-03-01 |
2007-09-13 |
Regents Of The University Of Colorado |
Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity
|
|
US7993648B2
(en)
|
2006-05-03 |
2011-08-09 |
The Regents of the Universitry of Colorado |
Immunostimulatory regimen comprising administering type 1 interferon and agonistic anti-CD40 antibody
|
|
US20080031887A1
(en)
|
2006-06-30 |
2008-02-07 |
Joseph Lustgarten |
Conjugates for inducing targeted immune responses and methods of making and using same
|
|
CA2691346A1
(en)
|
2006-06-30 |
2008-01-10 |
Baylor Research Institute |
Dendritic cells generated using gm-csf and interferon alpha and loaded with heat-treated and killed cancer cells
|
|
GB0614098D0
(en)
|
2006-07-15 |
2006-08-23 |
Mnl Pharma Ltd |
Immune response variegation with imino sugars
|
|
GB0620894D0
(en)
|
2006-10-20 |
2006-11-29 |
Univ Southampton |
Human immune therapies using a CD27 agonist alone or in combination with other immune modulators
|
|
US20080241139A1
(en)
|
2006-10-31 |
2008-10-02 |
Regents Of The University Of Colorado |
Adjuvant combinations comprising a microbial tlr agonist, a cd40 or 4-1bb agonist, and optionally an antigen and the use thereof for inducing a synergistic enhancement in cellular immunity
|
|
US20080149123A1
(en)
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
BRPI0807613A2
(pt)
|
2007-02-23 |
2014-06-10 |
Baylor Res Inst |
Ativação de antígeno humano presente em células através de clec-6
|
|
EP2522718B1
(en)
|
2007-02-23 |
2014-03-26 |
Baylor Research Institute |
Therapeutic applications of activation of human antigen-presenting cells through dectin-1
|
|
ES2582386T3
(es)
|
2007-03-01 |
2016-09-12 |
Symphogen A/S |
Composiciones de anticuerpos recombinantes contra el receptor del factor de crecimiento epidérmico
|
|
US20110182847A1
(en)
|
2007-06-15 |
2011-07-28 |
Randolph Noelle |
Use of tlr agonists and/or type 1 interferons to alleviate toxicity of tnf-r agonist therapeutic regimens
|
|
WO2009018500A1
(en)
|
2007-07-31 |
2009-02-05 |
The Johns Hopkins University |
Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders
|
|
WO2009059309A2
(en)
*
|
2007-11-01 |
2009-05-07 |
Panacea Pharmaceuticals, Inc. |
Furin-cleavable peptide linkers for drug-ligand conjugates
|
|
US20100098657A1
(en)
|
2007-12-27 |
2010-04-22 |
Schafer Peter H |
Method of Treating Cancer with Immunomodulatory Compounds and IgG
|
|
CA2713137C
(en)
|
2008-01-25 |
2017-10-24 |
Hadasit Medical Research Services And Development Ltd. |
Targeting of innate immune response to tumor site
|
|
HRP20161050T1
(hr)
|
2008-04-02 |
2016-11-18 |
Macrogenics, Inc. |
Her2/neu specifična protutijela i postupci njihovog korištenja
|
|
KR101892411B1
(ko)
|
2008-04-30 |
2018-08-27 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
|
US20090325315A1
(en)
|
2008-06-30 |
2009-12-31 |
Arkray, Inc. |
Detection method of target substance, detection reagent used for the same, and the uses thereof
|
|
CN106039307A
(zh)
|
2008-08-05 |
2016-10-26 |
东丽株式会社 |
用于治疗和预防癌症的药物组合物
|
|
US20100129383A1
(en)
|
2008-10-03 |
2010-05-27 |
The Governors Of The University Of Alberta |
Bifunctional fusion molecules for the delivery of antigens to professional antigen-presenting cells
|
|
US20100150942A1
(en)
|
2008-12-03 |
2010-06-17 |
Cantor Thomas L |
Affinity purified human polyclonal antibodies and methods of making and using them
|
|
WO2010121093A2
(en)
|
2009-04-17 |
2010-10-21 |
Lpath, Inc. |
Humanized antibody compositions and methods for binding lysophosphatidic acid
|
|
WO2010132622A2
(en)
|
2009-05-14 |
2010-11-18 |
The Regents Of The University Of California |
Anticd20-cpg conjugates and methods of treating b cell malignancies
|
|
CA2771609C
(en)
|
2009-08-18 |
2018-10-02 |
Ventirx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
|
EP2467380B1
(en)
|
2009-08-18 |
2016-11-30 |
Ventirx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
|
EP2475391B1
(en)
|
2009-09-09 |
2018-09-12 |
Centrose, LLC |
Extracellular targeted drug conjugates
|
|
CN102597775A
(zh)
|
2009-09-25 |
2012-07-18 |
佐马技术有限公司 |
筛选方法
|
|
GB0917054D0
(en)
|
2009-09-29 |
2009-11-11 |
Cytoguide As |
Agents, uses and methods
|
|
GB0917044D0
(en)
|
2009-09-29 |
2009-11-18 |
Cytoguide As |
Agents, uses and methods
|
|
US8518405B2
(en)
|
2009-10-08 |
2013-08-27 |
The University Of North Carolina At Charlotte |
Tumor specific antibodies and uses therefor
|
|
EP2532365B1
(en)
|
2010-02-04 |
2016-05-04 |
Toray Industries, Inc. |
Pharmaceutical composition for treatment and/or prevention of cancer
|
|
KR101801667B1
(ko)
|
2010-02-04 |
2017-11-27 |
도레이 카부시키가이샤 |
암의 치료 및/또는 예방용 의약 조성물
|
|
RU2598258C2
(ru)
|
2010-02-04 |
2016-09-20 |
Торэй Индастриз, Инк. |
Фармацевтическая композиция для лечения и/или профилактики рака
|
|
HUE025678T2
(en)
|
2010-02-04 |
2016-04-28 |
Toray Industries |
A pharmaceutical composition for the treatment and / or prevention of cancer
|
|
KR101805520B1
(ko)
|
2010-02-04 |
2017-12-07 |
도레이 카부시키가이샤 |
암의 치료 및/또는 예방용 의약 조성물
|
|
US9203872B2
(en)
|
2010-02-19 |
2015-12-01 |
Microsoft Technology Licensing, Llc |
Distributed connectivity policy enforcement with ICE
|
|
GB201003293D0
(en)
|
2010-02-26 |
2010-04-14 |
Adjuvantix Ltd |
Cancer vaccine
|
|
CA2791383C
(en)
|
2010-03-05 |
2022-09-20 |
The Johns Hopkins University |
Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
|
|
AU2011239706B2
(en)
|
2010-04-13 |
2015-08-20 |
Celldex Therapeutics Inc. |
Antibodies that bind human CD27 and uses thereof
|
|
US20120213771A1
(en)
|
2010-04-13 |
2012-08-23 |
Celldex Therapeutics Inc. |
Antibodies that bind human cd27 and uses thereof
|
|
MX2012012833A
(es)
|
2010-05-07 |
2012-11-30 |
Baylor Res Inst |
Cebado cruzado de celulas t cd8 positivas humanos moderada por inmunoreceptores de celulas dendriticas (dcir).
|
|
US8841417B2
(en)
|
2010-05-14 |
2014-09-23 |
Abbvie Inc. |
IL-1 binding proteins
|
|
SG185428A1
(en)
|
2010-06-08 |
2012-12-28 |
Genentech Inc |
Cysteine engineered antibodies and conjugates
|
|
WO2011155579A1
(ja)
|
2010-06-10 |
2011-12-15 |
北海道公立大学法人札幌医科大学 |
抗Trop-2抗体
|
|
EP2591099B1
(en)
|
2010-07-09 |
2020-11-18 |
Bioverativ Therapeutics Inc. |
Chimeric clotting factors
|
|
KR20130050966A
(ko)
|
2010-07-12 |
2013-05-16 |
씨오브이엑스 테크놀로지스 아일랜드 리미티드 |
다기능적 항체 접합체
|
|
RU2013110889A
(ru)
|
2010-08-13 |
2014-09-20 |
Бейлор Рисёч Инститьют |
Новые вакцинные адъюванты на основе адъювантов-антител, нацеливающих непосредственно на антигенпрезентирующие клетки
|
|
CN103458902B
(zh)
|
2010-10-01 |
2017-11-07 |
帆德制药股份有限公司 |
Tlr激动剂和联合治疗的治疗应用
|
|
US20120328605A1
(en)
|
2010-10-27 |
2012-12-27 |
Daniel Larocque |
Compositions and uses
|
|
EP2638066A4
(en)
|
2010-11-09 |
2015-06-03 |
Medimmune Llc |
ANTIBODY EQUIPMENT FOR HOMOGENEOUS CONJUGATION
|
|
WO2012092552A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
WO2012122396A1
(en)
|
2011-03-08 |
2012-09-13 |
Baylor Research Institute |
Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells
|
|
AR085573A1
(es)
|
2011-03-25 |
2013-10-09 |
Baylor Res Inst |
Composiciones y metodos de inmunizacion contra el virus de la hepatitis c
|
|
RS57324B1
(sr)
|
2011-04-20 |
2018-08-31 |
Medimmune Llc |
Antitela i drugi molekuli koji vezuju b7-h1 i pd-1
|
|
US8728486B2
(en)
|
2011-05-18 |
2014-05-20 |
University Of Kansas |
Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds
|
|
US20140088021A1
(en)
|
2011-05-27 |
2014-03-27 |
Nektar Therapeutics |
Water-Soluble Polymer-Linked Binding Moiety and Drug Compounds
|
|
MX347240B
(es)
|
2011-06-03 |
2017-04-20 |
3M Innovative Properties Co |
Ligadores heterobifuncionales con segmentos polietilenglicol y conjugados modificadores de la respuesta inmunitaria elaborados a partir de los mismos.
|
|
CA2838023C
(en)
|
2011-06-03 |
2019-08-13 |
3M Innovative Properties Company |
Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom
|
|
US9534056B2
(en)
|
2011-06-06 |
2017-01-03 |
Immungene Inc |
Engineered TAA antibody-TNFSF member ligand fusion molecules
|
|
ES2609846T3
(es)
|
2011-08-04 |
2017-04-24 |
Toray Industries, Inc. |
Composición farmacéutica para el tratamiento y/o prevención del cáncer pancreático
|
|
TR201802089T4
(tr)
|
2011-08-04 |
2018-03-21 |
Toray Industries |
Kanserin tedavisi ve/veya önlenmesi amacına yönelik ilaç bileşimi.
|
|
US9796775B2
(en)
|
2011-08-04 |
2017-10-24 |
Toray Industries, Inc. |
Method for detecting pancreatic cancer
|
|
PL2740798T3
(pl)
|
2011-08-04 |
2017-07-31 |
Toray Industries, Inc. |
Kompozycja leku do leczenia i/lub zapobiegania nowotworom
|
|
DK3351630T3
(da)
|
2011-08-04 |
2020-01-02 |
Toray Industries |
Farmaceutisk sammensætning omfattende anti caprin-1-antistoffer til behandling og/eller forebyggelse af cancer
|
|
CA2844034C
(en)
|
2011-08-04 |
2019-07-16 |
Toray Industries, Inc. |
Pharmaceutical composition for treatment and/or prophylaxis of cancer
|
|
RU2610428C2
(ru)
|
2011-08-04 |
2017-02-10 |
Торэй Индастриз, Инк. |
Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли
|
|
GB201113570D0
(en)
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
AU2012296613B2
(en)
|
2011-08-15 |
2016-05-12 |
Amplimmune, Inc. |
Anti-B7-H4 antibodies and their uses
|
|
CN104093418A
(zh)
|
2011-09-01 |
2014-10-08 |
诺华股份有限公司 |
金黄色葡萄球菌抗原的含佐剂制剂
|
|
JP2014527983A
(ja)
|
2011-09-19 |
2014-10-23 |
ザ ジョンズ ホプキンス ユニバーシティー |
癌免疫療法
|
|
NL2007536C2
(en)
|
2011-10-05 |
2013-04-08 |
Academisch Ziekenhuis Leiden Lumc |
Adjuvant compound.
|
|
US20130108619A1
(en)
|
2011-11-02 |
2013-05-02 |
Isaac Melamed |
Intravenous immunoglobulin processing, diagnostic, and treatment systems and methods
|
|
US10344261B2
(en)
|
2011-11-09 |
2019-07-09 |
Ascend Biopharmaceuticals Ltd |
Immunomodulatory conjugates
|
|
PH12014500932A1
(en)
|
2011-11-11 |
2014-06-09 |
Rinat Neuroscience Corp |
Antibodies specific for trop-2 and their uses
|
|
JP2015502397A
(ja)
|
2011-12-23 |
2015-01-22 |
ファイザー・インク |
部位特異的コンジュゲーションのための操作された抗体定常領域、ならびにそのための方法および使用
|
|
AR090410A1
(es)
|
2012-01-09 |
2014-11-12 |
Covx Technologies Ireland Ltd |
Anticuerpos mutantes y conjugacion de los mismos
|
|
JP6247226B2
(ja)
|
2012-01-10 |
2017-12-13 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
血液脳関門を越える治療分子の輸送の向上
|
|
US20130177574A1
(en)
|
2012-01-11 |
2013-07-11 |
Paul I. Terasaki Foundation Laboratory |
ANTI-HLA CLASS-Ib ANTIBODIES MIMIC IMMUNOREACTIVITY AND IMMUNOMODULATORY FUNCTIONS OF INTRAVENOUS IMMUNOGLOBULIN (IVIg) USEFUL AS THERAPEUTIC IVIg MIMETICS AND METHODS OF THEIR USE
|
|
RU2014111999A
(ru)
|
2012-02-01 |
2016-03-27 |
Компуджен Лтд. |
Антитела к C10RF32 и их применения для лечения рака
|
|
PT2818481T
(pt)
|
2012-02-21 |
2019-10-25 |
Toray Industries |
Composição farmacêutica para tratamento e/ou prevenção de cancro
|
|
KR102009236B1
(ko)
|
2012-02-21 |
2019-08-09 |
도레이 카부시키가이샤 |
암의 치료 및/또는 예방용 의약 조성물
|
|
US9573993B2
(en)
|
2012-02-21 |
2017-02-21 |
Toray Industries, Inc. |
Pharmaceutical composition for treatment of cancer comprising an anti-CAPRIN-1 peptide antibody
|
|
DK2818482T3
(da)
|
2012-02-21 |
2019-07-15 |
Toray Industries |
Farmaceutisk sammensætning til behandling af cancer
|
|
EA037979B1
(ru)
|
2012-02-27 |
2021-06-18 |
Амуникс Оперейтинг Инк. |
Композиции конъюгата xten и способы их получения
|
|
HUE036424T2
(hu)
|
2012-03-30 |
2018-07-30 |
Toray Industries |
Gyógyászati készítmény májrák kezelésére és/vagy megelõzésére
|
|
PL2832366T3
(pl)
|
2012-03-30 |
2018-04-30 |
Toray Industries, Inc. |
Kompozycja farmaceutyczna do leczenia i/lub zapobiegania rakowi pęcherzyka żółciowego
|
|
EP2836507A4
(en)
|
2012-04-13 |
2016-08-24 |
Whitehead Biomedical Inst |
SORTAS-MODIFIED VHH DOMAINS AND USES THEREOF
|
|
WO2013166110A1
(en)
|
2012-05-02 |
2013-11-07 |
Yale University |
Tlr-agonist-conjugated antibody recruiting molecules (tlr_arms)
|
|
US9599622B2
(en)
|
2012-05-30 |
2017-03-21 |
Life Technologies Corporation |
Fluorogenic pH-sensitive dyes and their methods of use (II)
|
|
EP2674170B1
(en)
|
2012-06-15 |
2014-11-19 |
Invivogen |
Novel compositions of TLR7 and/or TLR8 agonists conjugated to lipids
|
|
UA114108C2
(uk)
|
2012-07-10 |
2017-04-25 |
Борд Оф Ріджентс, Дзе Юніверсіті Оф Техас Сістем |
Моноклональне антитіло для застосування в діагностиці і терапії злоякісних пухлин і аутоімунного захворювання
|
|
CN112587658A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
|
US20140065096A1
(en)
|
2012-09-05 |
2014-03-06 |
Regen BioPharma, Inc. |
Cancer therapy by ex vivo activated autologous immune cells
|
|
ES2874493T3
(es)
|
2013-02-08 |
2021-11-05 |
Novartis Ag |
Sitios específicos para modificar anticuerpos para generar inmunoconjugados
|
|
EP2787005A1
(en)
|
2013-04-02 |
2014-10-08 |
Activartis Biotech GmbH |
Targeted cancer immune therapy
|
|
AR095882A1
(es)
|
2013-04-22 |
2015-11-18 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9
|
|
US20180104349A9
(en)
|
2013-04-28 |
2018-04-19 |
Gang Qin |
Novel linker, preparation method, and application thereof
|
|
WO2015014376A1
(en)
|
2013-07-31 |
2015-02-05 |
Biontech Ag |
Diagnosis and therapy of cancer involving cancer stem cells
|
|
KR102255616B1
(ko)
|
2013-08-09 |
2021-05-25 |
도레이 카부시키가이샤 |
암의 치료 및/또는 예방용 의약 조성물
|
|
US10836821B2
(en)
|
2013-10-15 |
2020-11-17 |
Sorrento Therapeutics, Inc. |
Drug-conjugates with a targeting molecule and two different drugs
|
|
GB201321242D0
(en)
|
2013-12-02 |
2014-01-15 |
Immune Targeting Systems Its Ltd |
Immunogenic compound
|
|
CN105934253A
(zh)
|
2013-12-17 |
2016-09-07 |
豪夫迈·罗氏有限公司 |
使用pd-1轴结合拮抗剂和抗her2抗体治疗her2阳性癌症的方法
|
|
KR20160099092A
(ko)
|
2013-12-17 |
2016-08-19 |
제넨테크, 인크. |
Ox40 결합 효능제 및 pd-1 축 결합 길항제를 포함하는 조합 요법
|
|
KR101941758B1
(ko)
|
2013-12-25 |
2019-01-24 |
다이이찌 산쿄 가부시키가이샤 |
항 trop2 항체-약물 컨쥬게이트
|
|
CN104861067A
(zh)
*
|
2014-01-10 |
2015-08-26 |
博笛生物科技有限公司 |
用于免疫疗法的化合物和组合物
|
|
AU2015205753A1
(en)
|
2014-01-10 |
2016-07-21 |
Birdie Biopharmaceuticals Inc. |
Compounds and compositions for treating HER2 positive tumors
|
|
CN104861063A
(zh)
*
|
2014-01-10 |
2015-08-26 |
博笛生物科技有限公司 |
靶向her2阳性肿瘤的化合物和组合物
|
|
EP3096787A4
(en)
|
2014-01-22 |
2018-02-07 |
The Board of Trustees of the Leland Stanford Junior University |
Methods and compositions for antibody and antibody-loaded dendritic cell mediated therapy
|
|
SG11201606761RA
(en)
|
2014-02-21 |
2016-09-29 |
Ecole Polytecnique Federale De Lausanne Epfl Epfl Tto |
Glycotargeting therapeutics
|
|
JP6357327B2
(ja)
|
2014-03-11 |
2018-07-11 |
株式会社クレハ |
フッ化ビニリデン系共重合体、その製造方法、ゲル電解質および非水系電池
|
|
WO2015138615A2
(en)
|
2014-03-12 |
2015-09-17 |
Irm Llc |
Specific sites for modifying antibodies to make immunoconjugates
|
|
HRP20230260T1
(hr)
|
2014-03-19 |
2023-04-28 |
Genzyme Corporation |
Glikoinženjering ciljajućih dijelova specifičan za mjesto
|
|
CA2944784A1
(en)
|
2014-04-11 |
2015-10-15 |
Medimmune, Llc |
Conjugated compounds comprising cysteine-engineered antibodies
|
|
MX377916B
(es)
|
2014-04-22 |
2025-03-10 |
Hoffmann La Roche |
Compuestos 4-amino-imidazoquinolina.
|
|
KR102511249B1
(ko)
|
2014-04-29 |
2023-03-20 |
진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. |
신규한 안정한 항체-약물 복합체, 이의 제조방법 및 이의 용도
|
|
US20170073415A1
(en)
|
2014-05-12 |
2017-03-16 |
Numab Ag |
Novel multispecific molecules and novel treatment methods based on such multispecific molecules
|
|
CN106536560B
(zh)
|
2014-05-23 |
2021-03-09 |
诺华股份有限公司 |
从含二硫化物的蛋白质制备缀合物的方法
|
|
WO2015187637A1
(en)
|
2014-06-02 |
2015-12-10 |
Baylor Research Institute |
Methods and compositions for treating allergy and inflammatory diseases
|
|
JP6449338B2
(ja)
|
2014-06-06 |
2019-01-09 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
グルココルチコイド誘導腫瘍壊死因子受容体(gitr)に対する抗体およびその使用
|
|
AU2015286043B2
(en)
|
2014-07-09 |
2020-08-20 |
Birdie Biopharmaceuticals Inc. |
Anti-PD-L1 combinations for treating tumors
|
|
CN105233291A
(zh)
|
2014-07-09 |
2016-01-13 |
博笛生物科技有限公司 |
用于治疗癌症的联合治疗组合物和联合治疗方法
|
|
WO2016011401A1
(en)
|
2014-07-18 |
2016-01-21 |
Kedl Ross M |
Immunostimulatory combinations and use thereof
|
|
CN107108738A
(zh)
|
2014-07-25 |
2017-08-29 |
西托姆克斯治疗公司 |
抗cd3抗体、可活化抗cd3抗体、多特异性抗cd3抗体、多特异性可活化抗cd3抗体及其使用方法
|
|
US20170233745A1
(en)
|
2014-08-20 |
2017-08-17 |
Tu Eindhoven |
Ureidopyrimidone supramolecular complexes for compound delivery into cells
|
|
WO2016032009A1
(en)
*
|
2014-08-27 |
2016-03-03 |
Kyushu University, National University Corporation |
Adjuvant
|
|
CN112587672A
(zh)
|
2014-09-01 |
2021-04-02 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
US9884866B2
(en)
|
2014-09-08 |
2018-02-06 |
Regents Of The University Of Minnesota |
Immunomodulators and immunomodulator conjugates
|
|
EP3662903A3
(en)
|
2014-10-03 |
2020-10-14 |
Novartis AG |
Combination therapies
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
WO2016057618A1
(en)
|
2014-10-09 |
2016-04-14 |
Wake Forest University Health Sciences |
Vaccine compositions and methods of use to treat neonatal subjects
|
|
GB201418004D0
(en)
|
2014-10-10 |
2014-11-26 |
Isis Innovation |
Polymer adjuvant
|
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
|
WO2016064749A2
(en)
|
2014-10-20 |
2016-04-28 |
Igenica Biotherapeutics, Inc. |
Novel antibody-drug conjugates and related compounds, compositions, and methods of use
|
|
WO2016064899A1
(en)
|
2014-10-21 |
2016-04-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for antibody and antibody-loaded dendritic cell mediated therapy
|
|
SMT202000413T1
(it)
|
2014-11-21 |
2020-09-10 |
Bristol Myers Squibb Co |
Anticorpi nei confronti di cd73 e loro usi
|
|
US20170266303A1
(en)
|
2014-11-25 |
2017-09-21 |
Endocyte, Inc. |
Methods of treating cancer by targeting tumor-associated macrophages
|
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
|
HRP20210200T1
(hr)
|
2014-12-31 |
2021-04-02 |
Checkmate Pharmaceuticals, Inc. |
Kombinirana antitumorska imunoterapija
|
|
JP6676058B2
(ja)
|
2015-01-14 |
2020-04-08 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
ヘテロアリーレン架橋したベンゾジアゼピン二量体、そのコンジュゲート、ならびに製造および使用方法
|
|
CA2968141C
(en)
|
2015-01-16 |
2020-08-04 |
Hsing-Mao CHU |
Molecular constructs with targeting and effector elements
|
|
ES2901501T3
(es)
|
2015-01-21 |
2022-03-22 |
Univ Leland Stanford Junior |
Uso de agonistas de TLR y agente anti-CD47 para mejorar la fagocitosis de las células cancerosas
|
|
WO2016145085A2
(en)
|
2015-03-09 |
2016-09-15 |
Celldex Therapeutics, Inc. |
Cd27 agonists
|
|
TWI703141B
(zh)
|
2015-03-12 |
2020-09-01 |
大陸商廣東東陽光藥業有限公司 |
作為丙型肝炎抑制劑的化合物及其在藥物中的應用
|
|
CN108112254B
(zh)
|
2015-03-13 |
2022-01-28 |
西托姆克斯治疗公司 |
抗-pdl1抗体、可活化的抗-pdl1抗体、及其使用方法
|
|
SI3274370T1
(sl)
|
2015-03-23 |
2020-02-28 |
Bayer Pharma Aktiengesellschaft |
Protitelesa proti CEACAM6 in njihova uporaba
|
|
US20180117171A1
(en)
|
2015-04-01 |
2018-05-03 |
President And Fellows Of Harvard College |
Immunoconjugates for programming or reprogramming of cells
|
|
JP6746845B2
(ja)
|
2015-04-22 |
2020-08-26 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
循環trop−2陽性癌細胞の単離、検出、診断及び/または特徴付け
|
|
CN114507283A
(zh)
|
2015-05-04 |
2022-05-17 |
西托姆克斯治疗公司 |
抗cd71抗体、可活化抗cd71抗体及其使用方法
|
|
AU2016258988A1
(en)
|
2015-05-04 |
2017-12-07 |
Cytomx Therapeutics, Inc |
Anti-ITGa3 antibodies, activatable anti-ITGa3 antibodies, and methods of use thereof
|
|
MX388350B
(es)
|
2015-05-04 |
2025-03-19 |
Cytomx Therapeutics Inc |
Anticuerpos anti-cd166, anticuerpos anti-cd166 activables, y metodos de uso de los mismos.
|
|
US20160324981A1
(en)
|
2015-05-08 |
2016-11-10 |
The California Institute For Biomedical Research |
Liver x receptor agonists and uses thereof
|
|
US10314854B2
(en)
|
2015-05-15 |
2019-06-11 |
University Of Iowa Foundation |
Methods for treating tumors in situ including intratumor injection of cytotoxic particles and immune checkpoint blockade therapy
|
|
US9988454B2
(en)
|
2015-05-20 |
2018-06-05 |
Immunwork Inc. |
Peptide core-based multi-arm linkers for treating central nervous system diseases
|
|
WO2016187656A1
(en)
|
2015-05-22 |
2016-12-01 |
La Trobe University |
Method of diagnosis of breast cancer
|
|
ES2789500T5
(es)
|
2015-05-29 |
2023-09-20 |
Hoffmann La Roche |
Procedimientos terapéuticos y de diagnóstico para el cáncer
|
|
PT3303396T
(pt)
|
2015-05-29 |
2023-01-30 |
Bristol Myers Squibb Co |
Anticorpos contra ox40 e utilizações dos mesmos
|
|
US20180267024A1
(en)
|
2015-06-08 |
2018-09-20 |
Lophius Biosciences Gmbh |
Composition for determination of cell-mediated immune responsiveness
|
|
CA2989269C
(en)
|
2015-06-15 |
2020-09-22 |
Robert Yongxin Zhao |
Hydrophilic linkers for conjugation of a cytotoxic agent or chromophore molecule to a cell-binding molecule
|
|
WO2016205566A1
(en)
|
2015-06-16 |
2016-12-22 |
The Regents Of The University Of California |
Fzd7 specific antibodies and vaccines to treat cancer and control stem cell function
|
|
US10766962B2
(en)
|
2015-06-16 |
2020-09-08 |
The Regents Of The University Of California |
FZD7 specific antibodies and vaccines to treat cancer and control stem cell function
|
|
US10975112B2
(en)
|
2015-06-16 |
2021-04-13 |
Hangzhou Dac Biotech Co., Ltd. |
Linkers for conjugation of cell-binding molecules
|
|
US20180296663A1
(en)
|
2015-06-17 |
2018-10-18 |
Curevac Ag |
Vaccine composition
|
|
GB201511546D0
(en)
|
2015-07-01 |
2015-08-12 |
Immatics Biotechnologies Gmbh |
Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
|
|
EP3317246A4
(en)
|
2015-07-04 |
2019-02-27 |
Suzhou M-conj Biotech Co., Ltd. |
SPECIFIC CONJUGATION OF A CELL BINDING MOLECULE
|
|
CN108449940B
(zh)
|
2015-07-12 |
2021-06-08 |
杭州多禧生物科技有限公司 |
与细胞结合分子的共轭偶联的桥连接体
|
|
CN108368170B
(zh)
|
2015-07-13 |
2022-04-15 |
西托姆克斯治疗公司 |
抗pd-1抗体、可活化抗pd-1抗体及其使用方法
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
PT3317301T
(pt)
|
2015-07-29 |
2021-07-09 |
Novartis Ag |
Terapias de associação compreendendo moléculas de anticorpo contra lag-3
|
|
CN114272371A
(zh)
|
2015-07-29 |
2022-04-05 |
诺华股份有限公司 |
包含抗pd-1抗体分子的联合疗法
|
|
US20180221503A1
(en)
|
2015-07-31 |
2018-08-09 |
Tarveda Therapeutics, Inc. |
Compositions and methods for immuno-oncology therapies
|
|
CA2994965A1
(en)
|
2015-08-06 |
2017-02-09 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for tumor therapy
|
|
TW201716084A
(zh)
|
2015-08-06 |
2017-05-16 |
葛蘭素史克智慧財產發展有限公司 |
組合物及其用途與治療
|
|
CA2991975C
(en)
|
2015-08-10 |
2021-04-06 |
Suzhou M-Conj Biotech Co., Ltd. |
Novel linkers and their uses in specific conjugation of drugs to a biological molecule
|
|
KR102685007B1
(ko)
|
2015-08-31 |
2024-07-12 |
쓰리엠 이노베이티브 프로퍼티즈 컴파니 |
구아니딘 치환된 이미다조[4,5-c] 고리 화합물
|
|
US10118925B2
(en)
|
2015-08-31 |
2018-11-06 |
3M Innovative Properties Company |
Imidazo[4,5-c] ring compounds containing substituted guanidine groups
|
|
JP2018527350A
(ja)
|
2015-09-01 |
2018-09-20 |
イミュンワーク インク.Immunwork Inc. |
血餅形成の予防及び/又は血栓症の治療のための分子構築物
|
|
US10799580B2
(en)
|
2015-09-09 |
2020-10-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Expression vector delivery system and use thereof for inducing an immune response
|
|
AU2016322813B2
(en)
|
2015-09-14 |
2021-04-01 |
Pfizer Inc. |
Novel imidazo (4,5-c) quinoline and imidazo (4,5-c)(1,5) naphthyridine derivatives as LRRK2 inhibitors
|
|
WO2017053720A1
(en)
|
2015-09-25 |
2017-03-30 |
Tarveda Therapeutics, Inc. |
RNAi CONJUGATES, PARTICLES AND FORMULATIONS THEREOF
|
|
EP3356371A4
(en)
|
2015-09-29 |
2020-06-24 |
The University of Chicago |
POLYMER CONJUGATE VACCINES
|
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
|
US20180303845A1
(en)
|
2015-11-02 |
2018-10-25 |
Ventirx Pharmaceuticals, Inc. |
Use of tlr8 agonists to treat cancer
|
|
US10988543B2
(en)
|
2015-11-11 |
2021-04-27 |
Opi Vi—Ip Holdco Llc |
Humanized anti-tumor necrosis factor alpha receptor 2 (anti-TNFR2) antibodies and methods of use thereof to elicit an immune response against a tumor
|
|
WO2017087280A1
(en)
|
2015-11-16 |
2017-05-26 |
Genentech, Inc. |
Methods of treating her2-positive cancer
|
|
CA2949033C
(en)
|
2015-11-30 |
2025-05-06 |
Pfizer Inc. |
ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION
|
|
KR101795388B1
(ko)
|
2015-12-02 |
2017-11-09 |
현대자동차 주식회사 |
차량용 자동변속기의 유성기어트레인
|
|
EP3386536A4
(en)
|
2015-12-07 |
2019-07-31 |
Opi Vi- IP Holdco LLC |
COMPOSITION OF ANTIBODY CONSTRUCT AGONIST CONJUGATES AND METHOD FOR USE THEREOF
|
|
US20170158772A1
(en)
|
2015-12-07 |
2017-06-08 |
Opi Vi - Ip Holdco Llc |
Compositions of antibody construct - agonist conjugates and methods of use thereof
|
|
EP4424322A3
(en)
|
2015-12-17 |
2025-04-16 |
Novartis AG |
Antibody molecules to pd-1 and uses thereof
|
|
WO2017117269A1
(en)
|
2015-12-29 |
2017-07-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for dectin-2 stimulation and cancer immunotherapy
|
|
CN115554406A
(zh)
|
2016-01-07 |
2023-01-03 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-cd20组合
|
|
CN115350279A
(zh)
|
2016-01-07 |
2022-11-18 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-her2组合
|
|
CN115252792A
(zh)
|
2016-01-07 |
2022-11-01 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-egfr组合
|
|
MY195114A
(en)
|
2016-02-04 |
2023-01-10 |
Robert Yongxin Zhao |
Specific Conjugation Linkers, Specific Immunoconjugates Thereof, Methods of Making and uses Such Conjugates Thereof
|
|
AU2017238172B2
(en)
|
2016-03-21 |
2024-06-27 |
Marengo Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
|
WO2017180834A1
(en)
|
2016-04-13 |
2017-10-19 |
Tarveda Therapeutics, Inc. |
Neurotensin receptor binding conjugates and formulations thereof
|
|
WO2017184619A2
(en)
|
2016-04-18 |
2017-10-26 |
Celldex Therapeutics, Inc. |
Agonistic antibodies that bind human cd40 and uses thereof
|
|
WO2017184735A1
(en)
|
2016-04-19 |
2017-10-26 |
Ifm Therapeutics, Inc |
Nlrp3 modulators
|
|
JP7104633B6
(ja)
|
2016-04-19 |
2023-12-22 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
Nlrp3修飾因子
|
|
CA3021669A1
(en)
|
2016-05-09 |
2017-11-16 |
Igm Biosciences, Inc. |
Anti-pd-l1 antibodies
|
|
TW201801751A
(zh)
|
2016-05-13 |
2018-01-16 |
塔維達治療公司 |
靶向構建體及其製劑
|
|
WO2017210246A2
(en)
|
2016-05-31 |
2017-12-07 |
Tarveda Therapeutics, Inc. |
Penicillamine conjugates and particles and formulations thereof
|
|
US12257352B2
(en)
|
2016-06-20 |
2025-03-25 |
The Regents Of The University Of Michigan |
Compositions and methods for delivery of biomacromolecule agents
|
|
US10858483B2
(en)
|
2016-07-06 |
2020-12-08 |
University Of Maryland, College Park |
Polyphosphazene polyelectrolytes and uses thereof
|
|
WO2018009916A1
(en)
*
|
2016-07-07 |
2018-01-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Antibody adjuvant conjugates
|
|
FI3922279T3
(fi)
|
2016-08-30 |
2025-02-04 |
Dana Farber Cancer Inst Inc |
Lääkkeenantokoostumuksia ja niiden käyttötapoja
|
|
US10640499B2
(en)
|
2016-09-02 |
2020-05-05 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
|
BE1024865B1
(fr)
|
2016-09-07 |
2018-07-31 |
Glaxosmithkline Biologicals Sa |
Derives d'imidazoquinoleine
|
|
AU2017323584C1
(en)
|
2016-09-09 |
2020-09-17 |
Novartis Ag |
Compounds and compositions as inhibitors of endosomal toll-like receptors
|
|
WO2018078620A1
(en)
|
2016-10-25 |
2018-05-03 |
Urogen Pharma Ltd. |
Immunomodulating treatments of body cavities
|
|
JP7206590B2
(ja)
|
2016-10-28 |
2023-01-18 |
東レ株式会社 |
癌の治療及び/又は予防用医薬組成物
|
|
CN116143678A
(zh)
|
2016-11-14 |
2023-05-23 |
杭州多禧生物科技有限公司 |
偶联连接体,含有此连接体的细胞结合分子-药物偶联物及其制备和应用
|
|
AU2017376460A1
(en)
|
2016-12-13 |
2019-06-20 |
Bolt Biotherapeutics, Inc. |
Antibody adjuvant conjugates
|
|
CN109963956B
(zh)
|
2016-12-15 |
2021-09-21 |
奥科宁克技术有限责任公司 |
耐腐蚀铝合金
|
|
RU2766582C2
(ru)
|
2016-12-23 |
2022-03-15 |
Ремд Биотерапьютикс, Инк. |
Иммунотерапия с применением антител, связывающих лиганд 1 белка программируемой смерти клеток (PD-L1)
|
|
US11248049B2
(en)
|
2016-12-23 |
2022-02-15 |
Remd Biotherapeutics, Inc. |
Immunotherapy using antibodies that bind Programmed Death 1 (PD-1)
|
|
CN110167598A
(zh)
|
2017-01-10 |
2019-08-23 |
尼克塔治疗公司 |
Tlr激动剂化合物的多臂聚合物缀合物以及相关的免疫治疗方法
|
|
WO2018140831A2
(en)
|
2017-01-27 |
2018-08-02 |
Silverback Therapeutics, Inc. |
Tumor targeting conjugates and methods of use thereof
|
|
CA3049842A1
(en)
|
2017-02-02 |
2018-08-09 |
Silverback Therapeutics, Inc. |
Construct-peptide compositions and methods of use thereof
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
WO2018156617A2
(en)
|
2017-02-22 |
2018-08-30 |
The Regents Of The University Of Michigan |
Compositions and methods for delivery of polymer / biomacromolecule conjugates
|
|
UA129583C2
(uk)
|
2017-03-06 |
2025-06-11 |
Мерк Патент Гмбх |
Водний фармацевтичний склад, який містить антитіло проти pd-l1 авелумаб
|
|
SG11201908131RA
(en)
|
2017-03-15 |
2019-10-30 |
Silverback Therapeutics Inc |
Benzazepine compounds, conjugates, and uses thereof
|
|
SG11201908456VA
(en)
|
2017-03-16 |
2019-10-30 |
Immunwork Inc |
Linker units and molecular constructs comprising same
|
|
WO2018175854A1
(en)
|
2017-03-23 |
2018-09-27 |
The Children's Medical Center Corporation |
Methods and compositions relating to adjuvants
|
|
CN110831979A
(zh)
|
2017-03-31 |
2020-02-21 |
酵活有限公司 |
肿瘤抗原递呈诱导物构建体及其用途
|
|
AU2018250226B2
(en)
|
2017-04-04 |
2025-04-24 |
Barinthus Biotherapeutics North America, Inc. |
Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
|
|
KR20210122319A
(ko)
|
2017-04-06 |
2021-10-08 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
비스-링키지를 사용한 세포독성 약물의 접합
|
|
US20180296685A1
(en)
|
2017-04-13 |
2018-10-18 |
Tarveda Therapeutics, Inc. |
Targeted constructs and formulations thereof
|
|
WO2018191746A1
(en)
*
|
2017-04-14 |
2018-10-18 |
Bolt Biotherapeutics, Inc. |
Immunoconjugate synthesis method
|
|
US12134654B2
(en)
|
2017-04-19 |
2024-11-05 |
Marengo Therapeutics, Inc. |
Multispecific molecules and uses thereof
|
|
CN108794467A
(zh)
|
2017-04-27 |
2018-11-13 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
AR111760A1
(es)
|
2017-05-19 |
2019-08-14 |
Novartis Ag |
Compuestos y composiciones para el tratamiento de tumores sólidos mediante administración intratumoral
|
|
CN111432828A
(zh)
|
2017-05-26 |
2020-07-17 |
约翰霍普金斯大学 |
用以调节免疫耐受的多功能抗体-配体捕获剂
|
|
AU2018279105A1
(en)
|
2017-06-07 |
2019-12-19 |
Silverback Therapeutics, Inc. |
Antibody conjugates of immune-modulatory compounds and uses thereof
|
|
WO2018227023A1
(en)
|
2017-06-07 |
2018-12-13 |
Silverback Therapeutics, Inc. |
Antibody construct conjugates
|
|
CN110769827A
(zh)
|
2017-06-23 |
2020-02-07 |
博笛生物科技有限公司 |
药物组合物
|
|
KR20200021095A
(ko)
|
2017-06-28 |
2020-02-27 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
덱틴-2 자극 및 암 면역요법을 위한 방법 및 조성물
|
|
WO2019023622A1
(en)
|
2017-07-27 |
2019-01-31 |
The Board Of Trustees Of The Leland Stanford Junior University |
POLYMERIC NANOPARTICLES FOR IMPROVED ANTICANCERIC IMMUNOTHERAPY
|
|
US10508115B2
(en)
|
2017-08-16 |
2019-12-17 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor
|
|
US10487084B2
(en)
|
2017-08-16 |
2019-11-26 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor
|
|
US10494370B2
(en)
|
2017-08-16 |
2019-12-03 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor
|
|
US10457681B2
(en)
|
2017-08-16 |
2019-10-29 |
Bristol_Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor
|
|
US10472361B2
(en)
|
2017-08-16 |
2019-11-12 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor
|
|
US12030940B2
(en)
|
2017-08-17 |
2024-07-09 |
Nektar Therapeutics |
Immunotherapeutic tumor treatment method
|
|
CN111511766B
(zh)
|
2017-10-13 |
2024-06-07 |
Ose免疫疗法 |
修饰的抗SIRPa抗体及其应用
|
|
WO2019084060A1
(en)
|
2017-10-24 |
2019-05-02 |
Silverback Therapeutics, Inc. |
CONJUGATES AND METHODS OF USE FOR THE SELECTIVE DELIVERY OF IMMUNOMODULATORY AGENTS
|
|
JP2021503005A
(ja)
|
2017-11-14 |
2021-02-04 |
ダイナバックス テクノロジーズ コーポレイション |
Tlr7/8アゴニスト化合物の切断可能なコンジュゲート、その調製方法および使用
|
|
AU2018385693A1
(en)
|
2017-12-15 |
2020-06-18 |
Silverback Therapeutics, Inc. |
Antibody construct-drug conjugate for the treatment of hepatitis
|
|
WO2019126240A1
(en)
|
2017-12-19 |
2019-06-27 |
Blaze Bioscience, Inc. |
Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof
|
|
CA3091468A1
(en)
|
2018-03-13 |
2019-09-19 |
Ose Immunotherapeutics |
Use of anti-human sirpa v1 antibodies and method for producing anti-sirpa v1 antibodies
|
|
US20210009711A1
(en)
|
2018-03-14 |
2021-01-14 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
EP3774798A1
(en)
|
2018-04-02 |
2021-02-17 |
Silverback Therapeutics, Inc. |
Alk5 inhibitors, conjugates, and uses thereof
|
|
CN108379591B
(zh)
|
2018-04-03 |
2022-03-29 |
深圳大学 |
免疫激动剂靶向化合物的合成及其应用
|
|
WO2019209811A1
(en)
|
2018-04-24 |
2019-10-31 |
Bristol-Myers Squibb Company |
Macrocyclic toll-like receptor 7 (tlr7) agonists
|
|
WO2019222676A1
(en)
|
2018-05-17 |
2019-11-21 |
Bolt Biotherapeutics, Inc. |
Immunoconjugates
|
|
IL311536A
(en)
|
2018-06-04 |
2024-05-01 |
Tufts College |
Binder-drug conjugates activated in the microenvironment and their related uses
|
|
TW202016148A
(zh)
|
2018-07-09 |
2020-05-01 |
大陸商艾比瑪特生物醫藥(上海)有限公司 |
滋養層抗原2(trop2)特異性抗體
|
|
WO2020023680A1
(en)
|
2018-07-24 |
2020-01-30 |
Torque Therapeutics, Inc. |
Tlr7/8 agonists and liposome compositions
|
|
US11554120B2
(en)
|
2018-08-03 |
2023-01-17 |
Bristol-Myers Squibb Company |
1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor
|
|
KR20210053924A
(ko)
|
2018-08-29 |
2021-05-12 |
볼트 바이오테라퓨틱스 인코퍼레이티드 |
Egfr을 표적으로 하는 면역접합체
|
|
EP3846807B1
(en)
|
2018-09-07 |
2023-08-02 |
Birdie Biopharmaceuticals, Inc. |
Imidazoquinoline compounds and uses thereof
|
|
WO2020056194A1
(en)
|
2018-09-12 |
2020-03-19 |
Silverback Therapeutics, Inc. |
Benzazepine compounds, conjugates, and uses thereof
|
|
CN113164618A
(zh)
|
2018-09-12 |
2021-07-23 |
希沃尔拜克治疗公司 |
用免疫刺激性缀合物治疗疾病的方法和组合物
|
|
CA3111580A1
(en)
|
2018-09-12 |
2020-03-19 |
Silverback Therapeutics, Inc. |
Antibody conjugates of toll-like receptor agonists
|
|
CA3112545A1
(en)
|
2018-09-12 |
2020-03-19 |
Silverback Therapeutics, Inc. |
Substituted benzazepine compounds, conjugates, and uses thereof
|
|
EP3873532A1
(en)
|
2018-10-31 |
2021-09-08 |
Novartis AG |
Dc-sign antibody drug conjugates
|
|
CN113348181A
(zh)
|
2018-10-31 |
2021-09-03 |
诺华股份有限公司 |
包含sting激动剂的dc-sign抗体缀合物
|
|
DK3886914T3
(da)
|
2018-11-30 |
2023-07-03 |
Bristol Myers Squibb Co |
Antistof omfattende en glutaminholdig letkæde-c-terminal forlængelse, konjugater deraf og fremgangsmåder samt anvendelser
|
|
US12478686B2
(en)
|
2018-12-12 |
2025-11-25 |
Bristol-Myers Squibb Company |
Antibodies modified for transglutaminase conjugation, conjugates thereof, and methods and uses
|
|
JP2022516093A
(ja)
|
2018-12-26 |
2022-02-24 |
バーディー バイオファーマシューティカルズ インコーポレイテッド |
癌の治療のための免疫調節薬の組み合わせおよび方法
|
|
AU2020205100A1
(en)
|
2019-01-04 |
2021-08-19 |
Trio Pharmaceuticals, Inc. |
Multi-specific protein molecules and uses thereof
|
|
MX2021007706A
(es)
|
2019-01-04 |
2021-08-05 |
Ascendis Pharma Oncology Div A/S |
Conjugados de agonistas de receptor de reconocimiento de patron.
|
|
JP7695885B2
(ja)
|
2019-02-12 |
2025-06-19 |
アンブルックス,インコーポレイテッド |
抗体-tlrアゴニストコンジュゲートを含有する組成物、その方法、及び使用
|
|
US20220226492A1
(en)
|
2019-03-15 |
2022-07-21 |
Bolt Biotherapeutics, Inc. |
Immunoconjugates Targeting HER2
|
|
US20220143012A1
(en)
|
2019-03-15 |
2022-05-12 |
Bolt Biotherapeutics, Inc. |
Macromolecule-Supported TLR Agonists
|
|
CA3130794A1
(en)
|
2019-03-15 |
2020-09-24 |
Bolt Biotherapeutics, Inc. |
Immunoconjugates targeting her2
|
|
US20220175762A1
(en)
|
2019-03-15 |
2022-06-09 |
Birdie Biopharmaceuticals, Inc. |
Immune modulatory compositions and methods for treating cancers
|
|
WO2020190760A1
(en)
|
2019-03-15 |
2020-09-24 |
Bolt Biotherapeutics, Inc. |
Immunoconjugates targeting cea
|
|
US20220226491A1
(en)
|
2019-03-15 |
2022-07-21 |
Bolt Biotherapeutics, Inc. |
Immunoconjugates Targeting PD-L1
|
|
US20220169737A1
(en)
|
2019-04-05 |
2022-06-02 |
Dren Bio, Inc. |
Methods of depleting disease causing agents via antibody targeted phagocytosis
|
|
EP3980080A1
(en)
|
2019-06-10 |
2022-04-13 |
Sutro Biopharma, Inc. |
Immunomodulator antibody drug conjugates and uses thereof
|
|
US20200390899A1
(en)
|
2019-06-13 |
2020-12-17 |
Bolt Biotherapeutics, Inc. |
Aminobenzazepine compounds, immunoconjugates, and uses thereof
|
|
CA3143156A1
(en)
|
2019-06-13 |
2020-12-17 |
Bolt Biotherapeutics, Inc. |
Macromolecule-supported aminobenzazepine compounds
|
|
CN114746420A
(zh)
|
2019-06-17 |
2022-07-12 |
苏特罗生物制药公司 |
用于癌症治疗和诊断的作为Toll样受体(TLR)7/8激动剂的1-(4-(氨基甲基)苄基)-2-丁基-2H-吡唑并[3,4-c]喹啉-4-胺衍生物及相关化合物以及其抗体药物偶联物
|
|
WO2020257407A1
(en)
|
2019-06-19 |
2020-12-24 |
Silverback Therapeutics, Inc. |
Anti-mesothelin antibodies and immunoconjugates thereof
|
|
CA3146661A1
(en)
|
2019-07-16 |
2021-01-21 |
Silverback Therapeutics, Inc. |
Alk5 inhibitors, conjugates, and uses thereof
|
|
US11339159B2
(en)
|
2019-07-17 |
2022-05-24 |
Pfizer Inc. |
Toll-like receptor agonists
|
|
EP4007758A1
(en)
|
2019-08-02 |
2022-06-08 |
Mersana Therapeutics, Inc. |
Bis-[n-((5-carbamoyl)-1h-benzo[d]imidazol-2-yl)-pyrazol-5-carboxamide] derivatives and related compounds as sting (stimulator of interferon genes) agonists for the treatment of cancer
|
|
EP4013456A1
(en)
|
2019-08-15 |
2022-06-22 |
Silverback Therapeutics, Inc. |
Formulations of benzazepine conjugates and uses thereof
|
|
WO2021046112A1
(en)
|
2019-09-03 |
2021-03-11 |
Bolt Biotherapeutics, Inc. |
Aminoquinoline compounds, immunoconjugates, and uses thereof
|
|
EP4025255A1
(en)
|
2019-09-04 |
2022-07-13 |
Bolt Biotherapeutics, Inc. |
Immunoconjugate synthesis method
|
|
CN114650844A
(zh)
|
2019-09-23 |
2022-06-21 |
西托姆克斯治疗公司 |
抗cd47抗体、可活化抗cd47抗体及其使用方法
|
|
US20220257785A1
(en)
|
2019-09-30 |
2022-08-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Knottin-immunostimulant conjugates and related compositions and methods
|
|
WO2021067242A1
(en)
|
2019-09-30 |
2021-04-08 |
Bolt Biotherapeutics, Inc. |
Amide-linked, aminobenzazepine immunoconjugates, and uses thereof
|
|
AU2020358726A1
(en)
|
2019-10-01 |
2022-04-07 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
US20210130473A1
(en)
|
2019-10-09 |
2021-05-06 |
Silverback Therapeutics, Inc. |
TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF
|
|
IL292396A
(en)
|
2019-10-25 |
2022-06-01 |
Bolt Biotherapeutics Inc |
Thianozapine immunoconjugates and uses thereof
|
|
CA3154969A1
(en)
|
2019-10-25 |
2021-04-29 |
Romas Kudirka |
Macromolecule-supported thienoazepine compounds, and uses thereof
|
|
US20230074558A1
(en)
|
2019-12-06 |
2023-03-09 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
|
US11702474B2
(en)
|
2019-12-17 |
2023-07-18 |
Pfizer Inc. |
Antibodies specific for CD47, PD-L1, and uses thereof
|
|
WO2021136475A1
(en)
|
2019-12-31 |
2021-07-08 |
Genequantum Healthcare (Suzhou) Co., Ltd. |
A drug conjugate and applications thereof
|
|
WO2021136483A1
(en)
|
2019-12-31 |
2021-07-08 |
Genequantum Healthcare (Suzhou) Co., Ltd. |
Anti-trop2 antibodies, antibody-drug conjugates, and application of the same
|
|
BR112022014358A2
(pt)
|
2020-01-21 |
2022-09-13 |
Bolt Biotherapeutics Inc |
Anticorpos anti-pd-l1
|
|
CN115175939A
(zh)
|
2020-01-21 |
2022-10-11 |
博尔特生物治疗药物有限公司 |
抗pd-l1抗体
|
|
US11179473B2
(en)
|
2020-02-21 |
2021-11-23 |
Silverback Therapeutics, Inc. |
Nectin-4 antibody conjugates and uses thereof
|
|
US20230165968A1
(en)
|
2020-02-25 |
2023-06-01 |
Bolt Biotherapeutics, Inc. |
Cancer treatment methods
|
|
WO2021202921A1
(en)
|
2020-04-01 |
2021-10-07 |
Altimmune Uk Limited |
Imidazoquinoline-type compounds and uses thereof
|
|
US20230173093A1
(en)
|
2020-04-10 |
2023-06-08 |
Seagen Inc. |
Charge variant linkers
|
|
KR20230005907A
(ko)
|
2020-05-01 |
2023-01-10 |
볼트 바이오테라퓨틱스 인코퍼레이티드 |
항-dectin-2 항체
|
|
WO2021226440A1
(en)
|
2020-05-08 |
2021-11-11 |
Bolt Biotherapeutics, Inc. |
Elastase-substrate, peptide linker immunoconjugates, and uses thereof
|