JP2019526273A5 - - Google Patents
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- JP2019526273A5 JP2019526273A5 JP2019518147A JP2019518147A JP2019526273A5 JP 2019526273 A5 JP2019526273 A5 JP 2019526273A5 JP 2019518147 A JP2019518147 A JP 2019518147A JP 2019518147 A JP2019518147 A JP 2019518147A JP 2019526273 A5 JP2019526273 A5 JP 2019526273A5
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- 101001137987 Homo sapiens Lymphocyte activation gene 3 protein Proteins 0.000 claims 6
- 102100020862 Lymphocyte activation gene 3 protein Human genes 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108010074708 B7-H1 Antigen Proteins 0.000 claims 3
- 102100024216 Programmed cell death 1 ligand 1 Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 229940027941 immunoglobulin g Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022052202A JP7464644B2 (ja) | 2016-06-20 | 2022-03-28 | Ｐｄ－ｌ１及びｌａｇ－３に結合する結合分子 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662352482P | 2016-06-20 | 2016-06-20 | |
| US62/352,482 | 2016-06-20 | ||
| PCT/EP2017/065073 WO2017220569A1 (en) | 2016-06-20 | 2017-06-20 | Binding molecules binding pd-l1 and lag-3 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022052202A Division JP7464644B2 (ja) | 2016-06-20 | 2022-03-28 | Ｐｄ－ｌ１及びｌａｇ－３に結合する結合分子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019526273A JP2019526273A (ja) | 2019-09-19 |
| JP2019526273A5 true JP2019526273A5 (enExample) | 2020-07-30 |
| JP7085709B2 JP7085709B2 (ja) | 2022-06-17 |
Family
ID=59631719
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019518147A Active JP7085709B2 (ja) | 2016-06-20 | 2017-06-20 | Ｐｄ－ｌ１及びｌａｇ－３に結合する結合分子 |
| JP2022052202A Active JP7464644B2 (ja) | 2016-06-20 | 2022-03-28 | Ｐｄ－ｌ１及びｌａｇ－３に結合する結合分子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022052202A Active JP7464644B2 (ja) | 2016-06-20 | 2022-03-28 | Ｐｄ－ｌ１及びｌａｇ－３に結合する結合分子 |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US11214620B2 (enExample) |
| EP (2) | EP3472207B1 (enExample) |
| JP (2) | JP7085709B2 (enExample) |
| KR (2) | KR20190019144A (enExample) |
| CN (1) | CN109563171B (enExample) |
| AR (1) | AR110101A1 (enExample) |
| AU (1) | AU2017283181B2 (enExample) |
| BR (1) | BR112018076519A8 (enExample) |
| CY (1) | CY1124232T1 (enExample) |
| DK (1) | DK3472207T3 (enExample) |
| ES (1) | ES2858091T3 (enExample) |
| HR (1) | HRP20210602T1 (enExample) |
| HU (1) | HUE053742T2 (enExample) |
| IL (1) | IL263730B2 (enExample) |
| LT (1) | LT3472207T (enExample) |
| MX (1) | MX2018016320A (enExample) |
| PL (1) | PL3472207T3 (enExample) |
| PT (1) | PT3472207T (enExample) |
| RS (1) | RS61705B1 (enExample) |
| SG (1) | SG11201811064TA (enExample) |
| SI (1) | SI3472207T1 (enExample) |
| SM (1) | SMT202100213T1 (enExample) |
| TW (1) | TW201803906A (enExample) |
| WO (1) | WO2017220569A1 (enExample) |
Families Citing this family (103)
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| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| TWI756187B (zh) | 2015-10-09 | 2022-03-01 | 美商再生元醫藥公司 | 抗ｌａｇ３抗體及其用途 |
| IL260937B2 (en) | 2016-02-06 | 2024-07-01 | Epimab Biotherapeutics Inc | Fabs-in-tandem immunoglobulin and uses thereof |
| TW201831513A (zh) | 2016-06-20 | 2018-09-01 | Ｆ星貝塔有限公司 | 結合物件(一) |
| EP3472207B1 (en) * | 2016-06-20 | 2021-01-20 | F-Star Delta Limited | Binding molecules binding pd-l1 and lag-3 |
| TWI640536B (zh) | 2016-06-20 | 2018-11-11 | 克馬伯有限公司 | 抗體 |
| US9567399B1 (en) | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
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| KR20240155979A (ko) | 2017-05-30 | 2024-10-29 | 브리스톨-마이어스 스큅 컴퍼니 | 항-lag-3 항체 또는 항-lag-3 항체 및 항-pd-1 또는 항-pd-l1 항체를 포함하는 조성물 |
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| GB201811410D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | OX40 Binding molecules |
| GB201811408D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | CD137 Binding Molecules |
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| SG11202100693UA (en) | 2018-07-26 | 2021-02-25 | Bristol Myers Squibb Co | Lag-3 combination therapy for the treatment of cancer |
| CA3117016A1 (en) | 2018-10-19 | 2020-04-23 | Bristol-Myers Squibb Company | Combination therapy for melanoma |
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| TWI756621B (zh) * | 2019-01-25 | 2022-03-01 | 大陸商信達生物製藥（蘇州）有限公司 | 新型雙特異性抗體分子以及同時結合pd-l1和lag-3的雙特異性抗體 |
| EP3715376A1 (en) | 2019-03-23 | 2020-09-30 | Ablevia biotech GmbH | Compound for the prevention or treatment of myasthenia gravis |
| US11986536B2 (en) | 2019-03-23 | 2024-05-21 | Ablevia Biotech Gmbh | Compound for the sequestration of undesirable antibodies in a patient |
| EP3715374A1 (en) | 2019-03-23 | 2020-09-30 | Ablevia biotech GmbH | Compound for the sequestration of undesirable antibodies in a patient |
| EP3715375A1 (en) | 2019-03-23 | 2020-09-30 | Ablevia biotech GmbH | Compound for the prevention or treatment of pre-eclampsia |
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2017
- 2017-06-20 EP EP17752291.9A patent/EP3472207B1/en active Active
- 2017-06-20 SI SI201730684T patent/SI3472207T1/sl unknown
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- 2017-06-20 RS RS20210453A patent/RS61705B1/sr unknown
- 2017-06-20 SG SG11201811064TA patent/SG11201811064TA/en unknown
- 2017-06-20 KR KR1020197001122A patent/KR20190019144A/ko not_active Abandoned
- 2017-06-20 DK DK17752291.9T patent/DK3472207T3/da active
- 2017-06-20 HU HUE17752291A patent/HUE053742T2/hu unknown
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- 2017-06-20 MX MX2018016320A patent/MX2018016320A/es unknown
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- 2017-06-20 CN CN201780048977.2A patent/CN109563171B/zh active Active
- 2017-06-20 WO PCT/EP2017/065073 patent/WO2017220569A1/en not_active Ceased
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- 2017-06-20 KR KR1020237006538A patent/KR102664891B1/ko active Active
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