JP2018193405A5 - - Google Patents
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- JP2018193405A5 JP2018193405A5 JP2018171794A JP2018171794A JP2018193405A5 JP 2018193405 A5 JP2018193405 A5 JP 2018193405A5 JP 2018171794 A JP2018171794 A JP 2018171794A JP 2018171794 A JP2018171794 A JP 2018171794A JP 2018193405 A5 JP2018193405 A5 JP 2018193405A5
- Authority
- JP
- Japan
- Prior art keywords
- heterocyclyl
- haloalkyl
- heteroaryl
- alkynyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 18
- 125000006647 (C3-C15) cycloalkyl group Chemical group 0.000 claims 18
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 18
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 18
- 125000003118 aryl group Chemical group 0.000 claims 18
- 125000001072 heteroaryl group Chemical group 0.000 claims 18
- 125000000623 heterocyclic group Chemical group 0.000 claims 18
- 125000006545 (C1-C9) alkyl group Chemical group 0.000 claims 16
- 229910052739 hydrogen Inorganic materials 0.000 claims 8
- 239000001257 hydrogen Substances 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 7
- 125000004414 alkyl thio group Chemical group 0.000 claims 6
- 150000002431 hydrogen Chemical class 0.000 claims 6
- 125000001475 halogen functional group Chemical group 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000003054 catalyst Substances 0.000 claims 1
- 239000012320 chlorinating reagent Substances 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019137759A JP6906021B2 (ja) | 2015-07-06 | 2019-07-26 | Ｃｏｔモジュレーターおよびその使用方法 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562189158P | 2015-07-06 | 2015-07-06 | |
| US62/189,158 | 2015-07-06 | ||
| US201562269060P | 2015-12-17 | 2015-12-17 | |
| US62/269,060 | 2015-12-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018500585A Division JP6430060B2 (ja) | 2015-07-06 | 2016-06-30 | Ｃｏｔモジュレーターおよびその使用方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019137759A Division JP6906021B2 (ja) | 2015-07-06 | 2019-07-26 | Ｃｏｔモジュレーターおよびその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018193405A JP2018193405A (ja) | 2018-12-06 |
| JP2018193405A5 true JP2018193405A5 (enExample) | 2019-09-05 |
| JP6781221B2 JP6781221B2 (ja) | 2020-11-04 |
Family
ID=56411943
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018500585A Active JP6430060B2 (ja) | 2015-07-06 | 2016-06-30 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2018171794A Active JP6781221B2 (ja) | 2015-07-06 | 2018-09-13 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2019137759A Active JP6906021B2 (ja) | 2015-07-06 | 2019-07-26 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2020208330A Active JP7138155B2 (ja) | 2015-07-06 | 2020-12-16 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2022065168A Withdrawn JP2022082816A (ja) | 2015-07-06 | 2022-04-11 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2024081151A Withdrawn JP2024100865A (ja) | 2015-07-06 | 2024-05-17 | Ｃｏｔモジュレーターおよびその使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018500585A Active JP6430060B2 (ja) | 2015-07-06 | 2016-06-30 | Ｃｏｔモジュレーターおよびその使用方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019137759A Active JP6906021B2 (ja) | 2015-07-06 | 2019-07-26 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2020208330A Active JP7138155B2 (ja) | 2015-07-06 | 2020-12-16 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2022065168A Withdrawn JP2022082816A (ja) | 2015-07-06 | 2022-04-11 | Ｃｏｔモジュレーターおよびその使用方法 |
| JP2024081151A Withdrawn JP2024100865A (ja) | 2015-07-06 | 2024-05-17 | Ｃｏｔモジュレーターおよびその使用方法 |
Country Status (41)
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| AR119594A1 (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos |
| CN115397511A (zh) | 2020-03-30 | 2022-11-25 | 吉利德科学公司 | Cot抑制剂化合物(s)-6-(((1-(双环[1.1.1]戊-1-基)-1h-1,2,3-三唑-4-基)2-甲基-1-氧代-1,2-二氢异喹啉-5-基)甲基)))氨基8-氯-(新戊基氨基)喹啉-3-甲腈的固体形式 |
| US11845737B2 (en) | 2020-04-02 | 2023-12-19 | Gilead Sciences, Inc. | Process for preparing a Cot inhibitor compound |
| TW202304435A (zh) | 2021-06-04 | 2023-02-01 | 美商基利科學股份有限公司 | 治療ｎａｓｈ之方法 |
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