ECSP17084635A - Moduladores cot y métodos de uso de los mismos - Google Patents

Moduladores cot y métodos de uso de los mismos

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Publication number
ECSP17084635A
ECSP17084635A ECIEPI201784635A ECPI201784635A ECSP17084635A EC SP17084635 A ECSP17084635 A EC SP17084635A EC IEPI201784635 A ECIEPI201784635 A EC IEPI201784635A EC PI201784635 A ECPI201784635 A EC PI201784635A EC SP17084635 A ECSP17084635 A EC SP17084635A
Authority
EC
Ecuador
Prior art keywords
modulators
methods
toc
cot
production
Prior art date
Application number
ECIEPI201784635A
Other languages
English (en)
Inventor
Elizabeth Bacon
John Link
Jeromy Cottell
Nathan Wright
Musong Kim
Scott Schroeder
Gayatri Balan
Thorsten Kirschberg
Neil Squires
Christopher Clark
William Watkins
Kirk Stevens
James Taylor
Sheila Zipfel
Chien-Hung Chou
Gary Phillips
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of ECSP17084635A publication Critical patent/ECSP17084635A/es

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    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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Abstract

La presente divulgación se refiere en general a moduladores de Cot (cáncer de tiroides Osaka) y métodos de uso y producción de los mismos.
ECIEPI201784635A 2015-07-06 2017-12-22 Moduladores cot y métodos de uso de los mismos ECSP17084635A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562189158P 2015-07-06 2015-07-06
US201562269060P 2015-12-17 2015-12-17

Publications (1)

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ECSP17084635A true ECSP17084635A (es) 2018-01-31

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ECIEPI201784635A ECSP17084635A (es) 2015-07-06 2017-12-22 Moduladores cot y métodos de uso de los mismos

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