JP2017501197A5 - - Google Patents

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Publication number
JP2017501197A5
JP2017501197A5 JP2016543735A JP2016543735A JP2017501197A5 JP 2017501197 A5 JP2017501197 A5 JP 2017501197A5 JP 2016543735 A JP2016543735 A JP 2016543735A JP 2016543735 A JP2016543735 A JP 2016543735A JP 2017501197 A5 JP2017501197 A5 JP 2017501197A5
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compound
dmf
group
formula
alkylating agent
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JP2016543735A
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JP6585057B2 (ja
JP2017501197A (ja
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Priority claimed from PCT/US2014/072569 external-priority patent/WO2015103144A1/en
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JP2016543735A 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法 Active JP6585057B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361922582P 2013-12-31 2013-12-31
US201361922572P 2013-12-31 2013-12-31
US61/922,572 2013-12-31
US61/922,582 2013-12-31
PCT/US2014/072569 WO2015103144A1 (en) 2013-12-31 2014-12-29 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019160781A Division JP2019218396A (ja) 2013-12-31 2019-09-04 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Publications (3)

Publication Number Publication Date
JP2017501197A JP2017501197A (ja) 2017-01-12
JP2017501197A5 true JP2017501197A5 (enExample) 2018-02-15
JP6585057B2 JP6585057B2 (ja) 2019-10-02

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ID=53480979

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016543746A Active JP6804297B2 (ja) 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法
JP2016543735A Active JP6585057B2 (ja) 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法
JP2019160781A Withdrawn JP2019218396A (ja) 2013-12-31 2019-09-04 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2016543746A Active JP6804297B2 (ja) 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019160781A Withdrawn JP2019218396A (ja) 2013-12-31 2019-09-04 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Country Status (24)

Country Link
US (8) US20150183750A1 (enExample)
EP (4) EP3862346A1 (enExample)
JP (3) JP6804297B2 (enExample)
CN (4) CN106068268A (enExample)
AP (1) AP2016009342A0 (enExample)
AU (2) AU2014373959B2 (enExample)
BR (2) BR102014033010B1 (enExample)
CA (2) CA2935594C (enExample)
CL (1) CL2016001677A1 (enExample)
CR (2) CR20160343A (enExample)
DO (1) DOP2016000163A (enExample)
EA (2) EA036389B1 (enExample)
EC (1) ECSP16064249A (enExample)
IL (3) IL246511B (enExample)
MX (2) MX392211B (enExample)
NI (1) NI201600094A (enExample)
NZ (2) NZ722438A (enExample)
PE (1) PE20161174A1 (enExample)
PH (1) PH12016501284A1 (enExample)
SG (2) SG11201605377VA (enExample)
TW (2) TWI722979B (enExample)
UA (2) UA129860C2 (enExample)
UY (2) UY35942A (enExample)
WO (2) WO2015103144A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015008444A (es) 2012-12-28 2015-09-23 Dow Agrosciences Llc Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida.
AU2013370493B2 (en) 2012-12-28 2017-08-17 Adama Makhteshim Ltd. N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxylate derivatives
KR102309245B1 (ko) 2012-12-31 2021-10-06 아다마 마켓심 리미티드 살진균제로서의 3-알킬-5-플루오로-4-치환된-이미노-3,4-디히드로피리미딘-2(1h)-온 유도체
FI3096619T3 (fi) 2013-12-31 2025-09-03 Adama Makhteshim Ltd Synergistisiä sienituhoaineseoksia sienten torjuntaan viljakasveissa
EA036389B1 (ru) 2013-12-31 2020-11-03 Адама Мактешим Лтд. 5-фтор-4-имино-3-(алкил/замещенный алкил)-1-(арилсульфонил)-3,4-дигидропиримидин-2(1h)-он и способы их получения
UY36964A (es) 2015-10-27 2017-05-31 Bayer Cropscience Ag Combinaciones de principios activos que comprenden un derivado de (tio) carboxamida y un compuesto funguicida
JP6922271B2 (ja) * 2016-03-11 2021-08-18 住友化学株式会社 植物病害防除組成物及び植物病害防除方法
EP3655396A1 (en) * 2017-07-17 2020-05-27 Adama Makhteshim Ltd. Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one
US12414559B2 (en) 2018-11-05 2025-09-16 Adama Makhteshim Ltd. Mixtures and compositions comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof
CA3295216A1 (en) 2019-07-22 2026-03-02 Adama Makhteshim Ltd. Fungicidal combinations, mixtures and compositions and uses thereof
WO2021059160A1 (en) 2019-09-23 2021-04-01 Adama Makhteshim Ltd. Process for preparing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine -(1h)-one
CN115776980A (zh) * 2020-03-09 2023-03-10 阿达玛马克西姆有限公司 用于制备5-氟-4-亚氨基-3-甲基-1-(甲苯-4-磺酰基)-3,4-二氢-1h-嘧啶-2-酮的方法
WO2021224802A1 (en) * 2020-05-04 2021-11-11 Adama Makhteshim Ltd. Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof
BR112023000205A2 (pt) 2020-07-08 2023-04-25 Adama Makhteshim Ltd Misturas fungicidas
PE20250069A1 (es) 2021-01-27 2025-01-13 Adama Makhteshim Ltd 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2(1h)-ona para control de enfermedades de plantas
AU2022268726A1 (en) 2021-05-04 2023-11-23 Adama Makhteshim Ltd. Crystalline forms of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4- dihydropyrimidin-2-one, and mixtures, compositions and methods of use thereof
CN118139845A (zh) 2021-09-15 2024-06-04 安道麦马克西姆有限公司 用于制备5-氟-4-亚氨基-3-甲基-1-(甲苯-4-磺酰基)-3,4-二氢-1h-嘧啶-2-酮的方法
UY40172A (es) 2022-03-03 2023-10-13 Adama Makhteshim Ltd Combinaciones, mezclas y composiciones fungicidas y usos de las mismas
AU2023275068A1 (en) 2022-05-26 2024-11-28 Adama Makhteshim Ltd. Fungicidal combinations, mixtures and compositions and uses thereof
PY2361414A (es) 2022-08-03 2024-02-21 Adama Makhteshim Ltd 5-fluoro-4-imino-3-metil-1-tosil -3,4-dihidropirimidin-2(1h)-ona para hongos resistentes a fungicidas
CN120882310A (zh) 2023-03-09 2025-10-31 安道麦马克西姆有限公司 杀真菌组合、混合物及组合物以及其用途
EP4680029A1 (en) 2023-03-14 2026-01-21 Adama Makhteshim Ltd. Liquid compositions containing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1h)-one and derivatives thereof and a uv absorber
CN121001998A (zh) 2023-03-23 2025-11-21 安道麦马克西姆有限公司 用于制备5-氟-4-亚氨基-3-甲基-1-(甲苯-4-磺酰基)-3,4-二氢-1h-嘧啶-2-酮的方法
IL326694A (en) 2023-08-31 2026-04-01 Adama Makhteshim Ltd Fungal combinations Mixtures, compositions and uses
IL308593A (en) 2023-11-15 2025-06-01 Adama Makhteshim Ltd Reducing environmental impact of fungicidal enhancement
WO2025114931A1 (en) 2023-11-28 2025-06-05 Adama Makhteshim Ltd. Fungicidal combinations, mixtures and compositions and uses thereof
WO2025203024A1 (en) 2024-03-26 2025-10-02 Adama Makhteshim Ltd. Process for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-1h-pyrimidin-2-one
WO2026038217A1 (en) 2024-08-15 2026-02-19 Adama Makhteshim Ltd. Mixtures and compositions comprising flumetylsulforim and methods of use thereof
WO2026083211A1 (en) 2024-10-16 2026-04-23 Adama Makhteshim Ltd. Mixtures and composition comprising thereof

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3309359A (en) 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
US3368938A (en) 1966-01-13 1968-02-13 Hoffmann La Roche Controlling fungi with 5-fluorocytosine
US3635977A (en) 1969-11-03 1972-01-18 American Cyanamid Co Certain 6-trifluoromethylcytosines and thiocytosines their synthesis and their use in the synthesis of uracisls and thiouracil
US3868373A (en) 1970-01-27 1975-02-25 Hoffmann La Roche 4-Amino-5-fluoro-2-tri(lower alkyl) silyloxypyrimidines
US4009272A (en) 1971-10-23 1977-02-22 Bayer Aktiengesellschaft Penicillins
CH579057A5 (enExample) 1973-09-07 1976-08-31 Hoffmann La Roche
JPS601793B2 (ja) 1979-12-06 1985-01-17 松下電器産業株式会社 カラ−テレビジョン受像機の画質改善装置
FR2530636A1 (fr) 1982-07-23 1984-01-27 Rhone Poulenc Agrochimie Nouveaux derives de la tetrahydro-2,3,6,7 5h-thiazolo (3,2-a) pyrimidine, leur preparation et leur utilisation comme herbicides
GR80171B (en) 1983-08-29 1985-01-02 Ciba Geigy Ag N-(2-nitrophenyl)-4-aminopyrimidine derivatives process for the preparation thereof and use
US4845081A (en) 1984-10-18 1989-07-04 University Of Florida Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes
EP0230922A2 (de) 1986-01-21 1987-08-05 Boehringer Ingelheim Kg Verwendung von Peptiden zur Herstellung von Mitteln zur Behandlung von Coronarerkrankungen oder organischem Hirnsyndrom
DE58908159D1 (de) 1988-03-09 1994-09-15 Ciba Geigy Ag Mittel zum Schutz von Pflanzen gegen Krankheiten.
DE3821711A1 (de) 1988-06-28 1990-02-08 Bayer Ag Thiazolopyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
US5118816A (en) * 1990-12-26 1992-06-02 American Cyanamid Company 2-aryl-5-(trifluoromethyl)-2-pyrroline compounds useful in the manufacture of insecticidal, nematocidal and acaricidal arylpyrroles
JP3109012B2 (ja) 1992-06-18 2000-11-13 クミアイ化学工業株式会社 チアゾロ［５，４−ｄ］ピリミジン誘導体及び農園芸用殺菌剤
JP3217191B2 (ja) 1992-07-16 2001-10-09 ビーエーエスエフ アクチェンゲゼルシャフト ヘテロ芳香族化合物およびこれを含有する植物保護剤
DE69618959T2 (de) 1995-07-05 2002-08-29 E.I. Du Pont De Nemours And Co., Wilmington Pyrimidone und ihre verwendug als fungizide
US6262058B1 (en) 1996-03-11 2001-07-17 Syngenta Crop Protection, Inc. Pyrimidin-4-one derivatives as pesticide
HRP970239B1 (en) * 1997-05-09 2004-04-30 Inst Ru Er Bouekovic Process for the preparation of sulfonyl-pyrimidine derivatives with antitumor activity
GT199900185A (es) 1998-11-06 2001-04-18 Novedosa pirimidin-4-enamina como fungicida.
MXPA03003278A (es) 2000-10-13 2005-07-01 Shire Biochem Inc Analogos de dioxolano para suministro intercelular mejorado.
US7914799B2 (en) 2001-08-27 2011-03-29 Immunitor USA, Inc. Anti-fungal composition
US20080269238A1 (en) 2004-04-01 2008-10-30 Takeda Pharmaceutical Company Limited Thiazolopyrimidine Derivative
CA2629295A1 (en) 2005-11-22 2007-05-31 Ishihara Sangyo Kaisha, Ltd. Germicide composition for agricultural and gardening applications and method for controlling plant disease
US20080004253A1 (en) 2006-06-30 2008-01-03 Bryan James Branstetter Thiazolopyrimidine modulators of TRPV1
US20100029483A1 (en) 2006-10-16 2010-02-04 Rhodia Inc. Agricultural adjuvant compositions, pesticide compositions, and methods for using such compositions
JP5035250B2 (ja) 2006-10-20 2012-09-26 住友金属工業株式会社 化学プラント用ニッケル材
US20100056468A1 (en) 2007-01-08 2010-03-04 University Health Network Pyrimidine Derivatives As Anticancer Agents
ES2549379T3 (es) 2008-01-22 2015-10-27 Dow Agrosciences Llc Derivados de 4-amino5-fluoropirimidina como fungicidas
PL2317851T3 (pl) 2008-08-01 2014-06-30 Dow Agrosciences Llc Zastosowanie 5-fluorocytozyny jako fungicydu
US8278341B2 (en) 2008-09-17 2012-10-02 Sri International Analogs of indole-3-carbinol and their use as agents against infection
DK2389375T3 (en) 2009-01-23 2015-08-24 Euro Celtique Sa Hydroxamsyrederivater
UA106889C2 (uk) 2009-08-07 2014-10-27 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні n1-ацил-5-фторпіримідинону
ES2506169T3 (es) 2009-08-07 2014-10-13 Dow Agrosciences Llc Derivados de 5-fluoro-2-oxopirimidina-1(2H)-carboxilato como fungicidas
UA112284C2 (uk) * 2009-08-07 2016-08-25 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні 5-фторпіримідинону
MX2012001622A (es) * 2009-08-07 2012-04-11 Dow Agrosciences Llc Derivados de n1-sulfonil-5-fluoropirimidinona.
UA107671C2 (en) 2009-08-07 2015-02-10 Dow Agrosciences Llc N1-substityted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives
BR112012007975A2 (pt) 2009-10-07 2016-03-29 Dow Agrosciences Llc composição fungicida sinergística contendo 5-fluorocitosina para controle fúngico em cereais
JP5784705B2 (ja) * 2010-04-26 2015-09-24 ダウ アグロサイエンシィズ エルエルシー Ｎ３置換−ｎ１−スルホニル−５−フルオロピリミジノン誘導体
EP2775842B1 (en) * 2011-08-17 2017-10-04 Adama Makhteshim Ltd. 1-substituted-5-fluoro-3,6-dihydro-6-imino-2(1H)-pyrimidinone derivatives as fungicidal agents for use in plant protection
WO2014073114A1 (en) 2012-11-07 2014-05-15 Toyota Jidosha Kabushiki Kaisha Method for producing a catalyst for fuel cells
AU2013370493B2 (en) 2012-12-28 2017-08-17 Adama Makhteshim Ltd. N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxylate derivatives
JP6336480B2 (ja) * 2012-12-28 2018-06-06 アダマ・マクテシム・リミテッド １−（置換ベンゾイル）−５−フルオロ−４−イミノ−３−メチル−３，４−ジヒドロピリミジン−２（１ｈ）−オンの誘導体
MX2015008444A (es) 2012-12-28 2015-09-23 Dow Agrosciences Llc Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida.
KR102309245B1 (ko) * 2012-12-31 2021-10-06 아다마 마켓심 리미티드 살진균제로서의 3-알킬-5-플루오로-4-치환된-이미노-3,4-디히드로피리미딘-2(1h)-온 유도체
FI3096619T3 (fi) 2013-12-31 2025-09-03 Adama Makhteshim Ltd Synergistisiä sienituhoaineseoksia sienten torjuntaan viljakasveissa
EA036389B1 (ru) 2013-12-31 2020-11-03 Адама Мактешим Лтд. 5-фтор-4-имино-3-(алкил/замещенный алкил)-1-(арилсульфонил)-3,4-дигидропиримидин-2(1h)-он и способы их получения
MA41272A (fr) 2014-12-23 2017-10-31 Adama Makhteshim Ltd 5-fluoro-4-imino-3-(alkyle/alkyle substitué)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one en tant que traitement des semences

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