CA2935594C - 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation - Google Patents
5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation Download PDFInfo
- Publication number
- CA2935594C CA2935594C CA2935594A CA2935594A CA2935594C CA 2935594 C CA2935594 C CA 2935594C CA 2935594 A CA2935594 A CA 2935594A CA 2935594 A CA2935594 A CA 2935594A CA 2935594 C CA2935594 C CA 2935594C
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
- C07D333/10—Thiophene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361922582P | 2013-12-31 | 2013-12-31 | |
| US201361922572P | 2013-12-31 | 2013-12-31 | |
| US61/922,582 | 2013-12-31 | ||
| US61/922,572 | 2013-12-31 | ||
| PCT/US2014/072566 WO2015103142A1 (en) | 2013-12-31 | 2014-12-29 | 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1- (arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2935594A1 CA2935594A1 (en) | 2015-07-09 |
| CA2935594C true CA2935594C (en) | 2022-05-03 |
Family
ID=53480979
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2935594A Active CA2935594C (en) | 2013-12-31 | 2014-12-29 | 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation |
| CA2935601A Active CA2935601C (en) | 2013-12-31 | 2014-12-29 | 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2935601A Active CA2935601C (en) | 2013-12-31 | 2014-12-29 | 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation |
Country Status (24)
| Country | Link |
|---|---|
| US (8) | US20150183749A1 (enExample) |
| EP (4) | EP3097096A4 (enExample) |
| JP (3) | JP6585057B2 (enExample) |
| CN (4) | CN106061972B (enExample) |
| AP (1) | AP2016009342A0 (enExample) |
| AU (2) | AU2014373961B2 (enExample) |
| BR (2) | BR102014033010B1 (enExample) |
| CA (2) | CA2935594C (enExample) |
| CL (1) | CL2016001677A1 (enExample) |
| CR (2) | CR20210172A (enExample) |
| DO (1) | DOP2016000163A (enExample) |
| EA (2) | EA201691353A1 (enExample) |
| EC (1) | ECSP16064249A (enExample) |
| IL (3) | IL246512B (enExample) |
| MX (2) | MX375727B (enExample) |
| NI (1) | NI201600094A (enExample) |
| NZ (2) | NZ722439A (enExample) |
| PE (1) | PE20161174A1 (enExample) |
| PH (1) | PH12016501284A1 (enExample) |
| SG (2) | SG11201605377VA (enExample) |
| TW (2) | TWI667229B (enExample) |
| UA (2) | UA122200C2 (enExample) |
| UY (2) | UY35942A (enExample) |
| WO (2) | WO2015103144A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110003118A (zh) | 2012-12-28 | 2019-07-12 | 阿达玛马克西姆股份有限公司 | 制备羧酸酯衍生物的方法 |
| AU2013370490B2 (en) | 2012-12-28 | 2018-05-10 | Adama Makhteshim Ltd. | N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxamide derivatives |
| KR102309245B1 (ko) | 2012-12-31 | 2021-10-06 | 아다마 마켓심 리미티드 | 살진균제로서의 3-알킬-5-플루오로-4-치환된-이미노-3,4-디히드로피리미딘-2(1h)-온 유도체 |
| JP6585057B2 (ja) | 2013-12-31 | 2019-10-02 | アダマ・マクテシム・リミテッド | ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法 |
| EA030056B1 (ru) | 2013-12-31 | 2018-06-29 | Адама Мактешим Лтд. | Синергетические фунгицидные смеси и синергетические фунгицидные композиции для борьбы с грибами |
| UY36964A (es) | 2015-10-27 | 2017-05-31 | Bayer Cropscience Ag | Combinaciones de principios activos que comprenden un derivado de (tio) carboxamida y un compuesto funguicida |
| JP6922271B2 (ja) * | 2016-03-11 | 2021-08-18 | 住友化学株式会社 | 植物病害防除組成物及び植物病害防除方法 |
| EP3655396A1 (en) * | 2017-07-17 | 2020-05-27 | Adama Makhteshim Ltd. | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one |
| IL282939B2 (en) * | 2018-11-05 | 2024-10-01 | Adama Makhteshim Ltd | Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4- dihydropyrimidin-2-one, and methods of use thereof |
| EP4003017A1 (en) | 2019-07-22 | 2022-06-01 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| BR112022005464A2 (pt) | 2019-09-23 | 2022-08-16 | Adama Makhteshim Ltd | Processo para a preparação de 5-(flúor-4-imino-3-metil)-1-tosil-3,4-diidropirimidina-(1h)-ona |
| CN115776980A (zh) * | 2020-03-09 | 2023-03-10 | 阿达玛马克西姆有限公司 | 用于制备5-氟-4-亚氨基-3-甲基-1-(甲苯-4-磺酰基)-3,4-二氢-1h-嘧啶-2-酮的方法 |
| AU2021267206A1 (en) | 2020-05-04 | 2022-12-08 | Adama Makhteshim Ltd. | Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof |
| AU2021306905A1 (en) | 2020-07-08 | 2023-02-23 | Adama Makhteshim Ltd. | Fungicidal mixtures |
| PE20250069A1 (es) | 2021-01-27 | 2025-01-13 | Adama Makhteshim Ltd | 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2(1h)-ona para control de enfermedades de plantas |
| CA3216622A1 (en) | 2021-05-04 | 2022-11-10 | Stefano Luca Giaffreda | Crystalline forms of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4- dihydropyrimidin-2-one, and mixtures, compositions and methods of use thereof |
| CN118139845A (zh) | 2021-09-15 | 2024-06-04 | 安道麦马克西姆有限公司 | 用于制备5-氟-4-亚氨基-3-甲基-1-(甲苯-4-磺酰基)-3,4-二氢-1h-嘧啶-2-酮的方法 |
| EP4486126A1 (en) | 2022-03-03 | 2025-01-08 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| US20250338845A1 (en) | 2022-05-26 | 2025-11-06 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| AU2023318916A1 (en) | 2022-08-03 | 2025-02-20 | Adama Makhteshim Ltd. | 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1h)-one for fungicide-resistant fungus |
| WO2024184859A1 (en) | 2023-03-09 | 2024-09-12 | Conese Salvatore | Fungicidal combinations, mixtures and compositions and uses thereof |
| AU2024236967A1 (en) | 2023-03-14 | 2025-09-25 | Adama Makhteshim Ltd. | Liquid compositions containing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1h)-one and derivatives thereof and a uv absorber |
| AR132182A1 (es) | 2023-03-23 | 2025-06-04 | Adama Makhteshim Ltd | Proceso para preparar 5-fluoro-4-imino-3-metil-1-(tolueno-4-sulfonil)-3,4-dihidro-1h-pirimidin-2-ona |
| AR133680A1 (es) | 2023-08-31 | 2025-10-22 | Adama Makhteshim Ltd | Combinaciones, mezclas y composiciones fungicidas y usos de las mismas |
| IL308593A (en) | 2023-11-15 | 2025-06-01 | Adama Makhteshim Ltd | Reducing environmental impact of fungicidal enhancement |
| WO2025114931A1 (en) | 2023-11-28 | 2025-06-05 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| WO2025203024A1 (en) | 2024-03-26 | 2025-10-02 | Adama Makhteshim Ltd. | Process for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-1h-pyrimidin-2-one |
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| US4009272A (en) | 1971-10-23 | 1977-02-22 | Bayer Aktiengesellschaft | Penicillins |
| CH579057A5 (enExample) | 1973-09-07 | 1976-08-31 | Hoffmann La Roche | |
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| EA022289B1 (ru) * | 2009-08-07 | 2015-12-30 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Производные n1-сульфонил-5-фторпиримидинона |
| NZ597638A (en) | 2009-08-07 | 2014-06-27 | Dow Agrosciences Llc | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives |
| UA106889C2 (uk) | 2009-08-07 | 2014-10-27 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні n1-ацил-5-фторпіримідинону |
| UA112284C2 (uk) | 2009-08-07 | 2016-08-25 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні 5-фторпіримідинону |
| RU2012118395A (ru) | 2009-10-07 | 2013-11-20 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Синергическая фунгицидная композиция, содержащая 5-фторцитозин, для борьбы с грибковыми болезнями зерновых культур |
| CA2797226C (en) * | 2010-04-26 | 2019-02-26 | Dow Agrosciences Llc | N3-substituted-n1-sulfonyl-5-fluoropyrimidinone derivatives |
| ES2646725T3 (es) * | 2011-08-17 | 2017-12-15 | Adama Makhteshim Ltd. | Derivados 1-sustituidos de 5-fluoro-3,6-dihidro-6-imino-2(1H)-pirimidinona como agentes fungicidas para uso en protección de plantas |
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| CN104994859B (zh) * | 2012-12-28 | 2018-10-26 | 阿达玛马克西姆股份有限公司 | 1-(取代的苯甲酰基)-5-氟-4-亚氨基-3-甲基-3,4-二氢嘧啶-2(1h)-酮衍生物 |
| CN110003118A (zh) | 2012-12-28 | 2019-07-12 | 阿达玛马克西姆股份有限公司 | 制备羧酸酯衍生物的方法 |
| AU2013370490B2 (en) | 2012-12-28 | 2018-05-10 | Adama Makhteshim Ltd. | N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxamide derivatives |
| KR102309245B1 (ko) * | 2012-12-31 | 2021-10-06 | 아다마 마켓심 리미티드 | 살진균제로서의 3-알킬-5-플루오로-4-치환된-이미노-3,4-디히드로피리미딘-2(1h)-온 유도체 |
| EA030056B1 (ru) | 2013-12-31 | 2018-06-29 | Адама Мактешим Лтд. | Синергетические фунгицидные смеси и синергетические фунгицидные композиции для борьбы с грибами |
| JP6585057B2 (ja) | 2013-12-31 | 2019-10-02 | アダマ・マクテシム・リミテッド | ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法 |
| MA41272A (fr) | 2014-12-23 | 2017-10-31 | Adama Makhteshim Ltd | 5-fluoro-4-imino-3-(alkyle/alkyle substitué)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one en tant que traitement des semences |
-
2014
- 2014-12-29 JP JP2016543735A patent/JP6585057B2/ja active Active
- 2014-12-29 EP EP14877285.8A patent/EP3097096A4/en not_active Ceased
- 2014-12-29 EA EA201691353A patent/EA201691353A1/ru unknown
- 2014-12-29 SG SG11201605377VA patent/SG11201605377VA/en unknown
- 2014-12-29 UA UAA201608339A patent/UA122200C2/uk unknown
- 2014-12-29 CR CR20210172A patent/CR20210172A/es unknown
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