|
BE580490A
(fr)
|
1958-07-15 |
1960-01-08 |
Merck & Co Inc |
Compositions et procédés pour abaisser la teneur en cholestérol du sang
|
|
US3383281A
(en)
|
1961-09-22 |
1968-05-14 |
Merck & Co Inc |
Method for binding bile acids in vivo
|
|
US3308020A
(en)
|
1961-09-22 |
1967-03-07 |
Merck & Co Inc |
Compositions and method for binding bile acids in vivo including hypocholesteremics
|
|
US3287370A
(en)
|
1965-06-08 |
1966-11-22 |
Mcneilab Inc |
Tetrahydrobenzothiepins
|
|
US3389144A
(en)
|
1965-06-08 |
1968-06-18 |
Mcneilab Inc |
5-pyridyl-2, 3, 4, 5-tetrahydrobenzothiepin-5-ols
|
|
DE1593760A1
(de)
|
1967-02-01 |
1972-06-08 |
Boehringer Sohn Ingelheim |
Verfahren zur Herstellung neuer Benz-epinderivate
|
|
US3444176A
(en)
|
1967-04-28 |
1969-05-13 |
Mcneilab Inc |
Certain 4-diloweralkylamino-lower alkyl - 5 - pyridyl (or phenyl)-2,3-dihydro - 1 - benzothiepins and derivatives thereof
|
|
GB1269551A
(en)
|
1969-03-27 |
1972-04-06 |
Science Union & Cie |
New tricyclic derivatives and process for their manufacture
|
|
NL7017227A
(enExample)
|
1969-12-27 |
1971-06-29 |
|
|
|
US3694446A
(en)
|
1970-02-24 |
1972-09-26 |
William J Houlihan |
5-(substituted-benzyl)-benzocycloheptenes and-1-benzthiepines
|
|
CH537404A
(de)
|
1970-09-24 |
1973-05-31 |
Sandoz Ag |
Verfahren zur Herstellung neuer Thiophenderivate
|
|
CH531000A
(de)
|
1970-03-11 |
1972-11-30 |
Sandoz Ag |
Verfahren zur Herstellung neuer Benzocycloheptathiophene
|
|
US3821249A
(en)
|
1970-03-13 |
1974-06-28 |
En Nom Collectif Science Union |
Dibenzothiazefin derivatives
|
|
US3758528A
(en)
|
1970-03-13 |
1973-09-11 |
Science Union & Cie |
Tricyclic compounds
|
|
GB1348642A
(en)
|
1970-10-15 |
1974-03-20 |
Howard A N |
Hypocholesterolaemic compositions
|
|
US3769399A
(en)
|
1971-03-05 |
1973-10-30 |
L Hagerman |
Intestinal bile acid binding process and compositions
|
|
JPS4711953U
(enExample)
|
1971-03-08 |
1972-10-12 |
|
|
|
GB1428110A
(en)
|
1972-05-30 |
1976-03-17 |
Reckitt & Colmann Prod Ltd |
Pharmaceutical antihypertensive and vasodilator compositions
|
|
US3974272A
(en)
|
1972-09-01 |
1976-08-10 |
Merck & Co., Inc. |
Palatable cholestyramine coacervate compositions
|
|
CH582699A5
(enExample)
|
1973-03-26 |
1976-12-15 |
Sandoz Ag |
|
|
US4044010A
(en)
|
1973-03-30 |
1977-08-23 |
Hoffmann-La Roche Inc. |
Dibenzo[b,f] thiepins bearing piperazinyl substitution
|
|
US3954764A
(en)
|
1973-03-30 |
1976-05-04 |
Hoffmann-La Roche Inc. |
Dibenzo [b,f]thiepins bearing piperazinyl substitution
|
|
CH593970A5
(en)
|
1973-03-30 |
1977-12-30 |
Hoffmann La Roche |
10-(4-Substd. piperazino) dibenzo (b,f) thiepins - CNS depressants without cataleptic side-effects
|
|
US3928383A
(en)
|
1973-06-08 |
1975-12-23 |
Hoffmann La Roche |
Propynylamine-substituted dibenzo{8 b,f{9 thiepins and dibenz{8 b,f{9 oxepins
|
|
SE7504508L
(sv)
|
1974-05-10 |
1975-11-11 |
Ciba Geigy Ag |
Nya heterocykliska s-imino-s-oxider.
|
|
SE420725B
(sv)
|
1974-09-26 |
1981-10-26 |
Ciba Geigy Ag |
Sett att framstella 2,3-dihydro-1-benstiepin-4-karboxylsyraamider
|
|
US4252790A
(en)
|
1974-10-23 |
1981-02-24 |
Interx Research Corporation |
Method for treating gastric ulcer-prone patients
|
|
GB1566609A
(en)
|
1977-03-10 |
1980-05-08 |
Reckitt & Colmann Prod Ltd |
Pharmaceutical compositions containing cholestyramine and alginic acid
|
|
US4207239A
(en)
|
1977-10-31 |
1980-06-10 |
The Upjohn Company |
Benzothiepins
|
|
US4153612A
(en)
|
1977-10-31 |
1979-05-08 |
The Upjohn Company |
2-Benzoxepins
|
|
US4251526A
(en)
|
1977-10-31 |
1981-02-17 |
Mccall John M |
2-Benzothiepins and compositions and methods of use therefore
|
|
US4247533A
(en)
|
1978-05-01 |
1981-01-27 |
The Rockefeller University |
Hemoglobin A1c radioimmunoassay
|
|
IT1106718B
(it)
|
1978-12-21 |
1985-11-18 |
Alfa Farmaceutici Spa |
Composizioni a base di resine anioniche salificate farmacologicamente attive
|
|
US5169857A
(en)
|
1988-01-20 |
1992-12-08 |
Bayer Aktiengesellschaft |
7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
|
|
AU548253B2
(en)
|
1981-05-11 |
1985-12-05 |
Pierre Fabre S.A. |
Benzoxepine derivatives and sulphur and nitrogen analogues thereof
|
|
US4647459A
(en)
|
1983-07-20 |
1987-03-03 |
Warner-Lambert Company |
Confectionery compositions containing magnesium trisilicate adsorbates
|
|
US4771072A
(en)
|
1985-01-10 |
1988-09-13 |
Tanabe Seiyaku Co., Ltd. |
Alkoxynaphthalene derivatives
|
|
AU597671B2
(en)
|
1986-06-20 |
1990-06-07 |
Suntory Limited |
2-Phenylbenzoxepin derivative
|
|
JPS6310746A
(ja)
|
1986-07-01 |
1988-01-18 |
Tanabe Seiyaku Co Ltd |
ナフタレン誘導体
|
|
US4895723A
(en)
|
1986-09-08 |
1990-01-23 |
Amer And Company |
Cholestyramine compositions and method for preparation thereof
|
|
US4814354A
(en)
|
1986-09-26 |
1989-03-21 |
Warner-Lambert Company |
Lipid regulating agents
|
|
ZA876930B
(en)
|
1986-10-07 |
1988-05-25 |
Hoffmann La Roche |
Pharmaceutical compositions
|
|
AU626881B2
(en)
|
1988-07-14 |
1992-08-13 |
F. Hoffmann-La Roche Ag |
Benzofused heterocyclics used as pharmaceuticals
|
|
US5164387A
(en)
|
1988-07-14 |
1992-11-17 |
Hoffmann-Laroche Inc. |
Condensed heterocyclic compounds
|
|
US5158943A
(en)
|
1988-11-21 |
1992-10-27 |
Takeda Chemical Industries, Ltd. |
Sulfur-containing heterocyclic compounds
|
|
US4874744A
(en)
|
1989-03-13 |
1989-10-17 |
University Of Cincinnati |
Method of using melanocyte stimulating hormone as dermatis treatment
|
|
US5275823A
(en)
|
1989-04-27 |
1994-01-04 |
Smith Kline & French Laboratories Ltd. |
Pharmaceutical compositions
|
|
DE3930696A1
(de)
|
1989-09-14 |
1991-03-28 |
Hoechst Ag |
Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
|
|
US4997665A
(en)
|
1989-10-05 |
1991-03-05 |
Michigan Biotechnology Institute |
Dietary fibers and a process for their production
|
|
FR2661676A1
(fr)
|
1990-05-02 |
1991-11-08 |
Lipha |
Derives d'amino benzocycloalcanes, procedes de preparation et medicaments les contenant.
|
|
NZ240846A
(en)
|
1990-12-06 |
1994-04-27 |
Hoechst Ag |
Dimeric bile acid derivatives; preparatory processes and pharmaceutical compositions
|
|
IT1245890B
(it)
|
1991-04-12 |
1994-10-25 |
Alfa Wassermann Spa |
Formulazioni farmaceutiche per uso orale gastroresistenti contenenti acidi biliari.
|
|
AU1886892A
(en)
|
1991-04-12 |
1992-11-17 |
Schering Corporation |
Bicyclic amides as inhibitors of acyl-coenzyme a: cholesterol acyl transferase
|
|
ATE175954T1
(de)
|
1991-10-17 |
1999-02-15 |
Shionogi & Co |
Verfahren zum herstellen von lignin-analoga und ausgangsprodukte dafür
|
|
AU653658B2
(en)
|
1991-12-20 |
1994-10-06 |
Hoechst Aktiengesellschaft |
Polymers and oligomers of bile acid derivatives, process for their preparation and their use as pharmaceuticals
|
|
GB9203347D0
(en)
|
1992-02-17 |
1992-04-01 |
Wellcome Found |
Hypolipidaemic compounds
|
|
DK0573848T3
(da)
|
1992-06-12 |
1998-08-10 |
Hoechst Ag |
Galdesyrederivater, fremgangsmåde til deres fremstilling og anvendelse af disse forbindelser som lægemidler
|
|
US5415872A
(en)
|
1992-06-22 |
1995-05-16 |
Digestive Care Inc. |
Compositions of gastric acid-resistant microspheres containing salts of bile acids
|
|
FR2698873B1
(fr)
|
1992-12-07 |
1995-02-24 |
Lipha |
Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant.
|
|
IL108634A0
(en)
|
1993-02-15 |
1994-05-30 |
Wellcome Found |
Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them
|
|
IL108633A
(en)
|
1993-02-15 |
1998-07-15 |
Wellcome Found |
History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them
|
|
US5594001A
(en)
|
1993-04-08 |
1997-01-14 |
The Dupont Merck Pharmaceutical Company |
Polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders
|
|
EP0646570B1
(en)
|
1993-04-16 |
1998-06-24 |
Shionogi & Co., Ltd. |
Process for producing lignan compound
|
|
DE4314583A1
(de)
|
1993-04-29 |
1994-11-03 |
Astra Chem Gmbh |
Colestyramin enthaltende Zusammensetzung und Verfahren zu deren Herstellung
|
|
TW289021B
(enExample)
|
1993-05-08 |
1996-10-21 |
Hoechst Ag |
|
|
TW289020B
(enExample)
|
1993-05-08 |
1996-10-21 |
Hoechst Sktiengesellschaft |
|
|
EP0624593A3
(de)
|
1993-05-08 |
1995-06-07 |
Hoechst Ag |
Gallensäurederivate, Verfahren zu ihrer Herstellung und Verwendung dieser Verbindungen als Arzneimittel.
|
|
US5607669A
(en)
|
1994-06-10 |
1997-03-04 |
Geltex Pharmaceuticals, Inc. |
Amine polymer sequestrant and method of cholesterol depletion
|
|
DK0640344T3
(da)
|
1993-08-30 |
1999-07-05 |
Medichemie Ag |
Ursodesoxycholsyreholdigt lægemiddel i flydende administreringsform
|
|
US5589358A
(en)
|
1993-12-29 |
1996-12-31 |
Univ Wake Forest |
Ileal bile acid transporter compositions and methods
|
|
US5491152A
(en)
|
1994-03-23 |
1996-02-13 |
The Du Pont Merck Pharmaceutical Company |
Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis
|
|
TW474813B
(en)
|
1994-06-10 |
2002-02-01 |
Geltex Pharma Inc |
Alkylated composition for removing bile salts from a patient
|
|
KR970005178Y1
(ko)
|
1994-07-06 |
1997-05-24 |
김상수 |
개량형 노통연관 보일러
|
|
ZA956647B
(en)
|
1994-08-10 |
1997-02-10 |
Wellcome Found |
Hypolipidaemic compounds.
|
|
WO1996008484A1
(en)
|
1994-09-13 |
1996-03-21 |
Monsanto Company |
Novel benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
US6262277B1
(en)
|
1994-09-13 |
2001-07-17 |
G.D. Searle And Company |
Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
US6268392B1
(en)
|
1994-09-13 |
2001-07-31 |
G. D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
|
|
US6107494A
(en)
|
1994-09-13 |
2000-08-22 |
G.D. Searle And Company |
Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
US6642268B2
(en)
|
1994-09-13 |
2003-11-04 |
G.D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
|
|
US5994391A
(en)
|
1994-09-13 |
1999-11-30 |
G.D. Searle And Company |
Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
US5547975A
(en)
|
1994-09-20 |
1996-08-20 |
Talley; John J. |
Benzopyranopyrazolyl derivatives for the treatment of inflammation
|
|
US6034118A
(en)
|
1994-11-04 |
2000-03-07 |
Gilead Sciences, Inc. |
Thiepane compounds
|
|
GB9423172D0
(en)
|
1994-11-17 |
1995-01-04 |
Wellcom Foundation The Limited |
Hypolipidemic benzothiazepines
|
|
US5721103A
(en)
|
1994-12-30 |
1998-02-24 |
Ligand Pharmaceuticals Incorporated |
Trienoic retinoid compounds and methods
|
|
US6861053B1
(en)
|
1999-08-11 |
2005-03-01 |
Cedars-Sinai Medical Center |
Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
|
|
TW438587B
(en)
|
1995-06-20 |
2001-06-07 |
Takeda Chemical Industries Ltd |
A pharmaceutical composition for prophylaxis and treatment of diabetes
|
|
US5886016A
(en)
|
1995-09-15 |
1999-03-23 |
G.D. Searle & Co. |
Benzopyranopyrazolyl derivatives for the treatment of inflammation
|
|
PL186714B1
(pl)
|
1995-11-02 |
2004-02-27 |
Warner Lambert Co |
Kompozycja farmaceutyczna do regulowania stężenialipidów do ssaka
|
|
US6069167A
(en)
|
1996-01-16 |
2000-05-30 |
University Technology Corporation |
Use of antioxidant agents to treat cholestatic liver disease
|
|
GB9601697D0
(en)
|
1996-01-27 |
1996-03-27 |
Pfizer Ltd |
Therapeutic agents
|
|
JP2001526627A
(ja)
|
1996-03-11 |
2001-12-18 |
ジー．ディー．サール アンド カンパニー |
回腸胆汁酸輸送及びタウロコール酸塩吸収の阻害剤としての活性を有する新規ベンゾチエピン類
|
|
DE19616486C5
(de)
|
1996-04-25 |
2016-06-30 |
Royalty Pharma Collection Trust |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
|
WO1998007749A1
(en)
|
1996-08-23 |
1998-02-26 |
Human Genome Sciences, Inc. |
Novel human growth factors
|
|
JPH1072371A
(ja)
|
1996-08-28 |
1998-03-17 |
Sankyo Co Ltd |
回腸型胆汁酸トランスポーター阻害剤
|
|
US6251852B1
(en)
|
1996-09-18 |
2001-06-26 |
Merck & Co., Inc. |
Combination therapy for reducing the risks associated with cardiovascular disease
|
|
US5908830A
(en)
|
1996-10-31 |
1999-06-01 |
Merck & Co., Inc. |
Combination therapy for the treatment of diabetes and obesity
|
|
GB9704208D0
(en)
|
1997-02-28 |
1997-04-16 |
Glaxo Group Ltd |
Chemical compounds
|
|
BR9808013A
(pt)
|
1997-03-11 |
2001-09-25 |
Searle & Co |
Terapia de combinação empregando benzotiepinas de inibição de transporte de ácido biliar ileal e inibidores de redutase de hmg co-a
|
|
DK0864582T3
(da)
|
1997-03-14 |
2003-09-29 |
Aventis Pharma Gmbh |
Hypolidemiske 1,4-benzothiazepin-1,1-dioxider
|
|
DE19845402B4
(de)
|
1998-10-02 |
2005-04-07 |
Aventis Pharma Deutschland Gmbh |
Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
ES2223091T3
(es)
|
1997-04-04 |
2005-02-16 |
Aventis Pharma Deutschland Gmbh |
Derivados de propanolamina hipolipidemicos.
|
|
IT1292092B1
(it)
|
1997-06-05 |
1999-01-25 |
Geange Ltd |
Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali
|
|
WO1998056757A1
(fr)
|
1997-06-11 |
1998-12-17 |
Sankyo Company, Limited |
Derives de benzylamine
|
|
GB9714274D0
(en)
|
1997-07-08 |
1997-09-10 |
Zeneca Ltd |
Pharmaceutical composition
|
|
US6180660B1
(en)
|
1997-08-26 |
2001-01-30 |
Merck & Co., Inc. |
Cholesterol-lowering therapy
|
|
US6066336A
(en)
|
1997-09-29 |
2000-05-23 |
Bristol-Myers Squibb Company |
Cholesterol-lowering tablets
|
|
US5900233A
(en)
|
1997-10-16 |
1999-05-04 |
Day; Charles E. |
Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and its use in treating irritable bowel syndrome
|
|
US6245797B1
(en)
|
1997-10-22 |
2001-06-12 |
Merck & Co., Inc. |
Combination therapy for reducing the risks associated with cardio-and-cerebrovascular disease
|
|
US6083497A
(en)
|
1997-11-05 |
2000-07-04 |
Geltex Pharmaceuticals, Inc. |
Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
|
|
DE19755480A1
(de)
|
1997-12-13 |
1999-06-24 |
Gruenenthal Gmbh |
Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen
|
|
PT1042314E
(pt)
|
1997-12-19 |
2003-07-31 |
Searle & Co |
Metodo de preparacao de oxidos de tetra-hidrobenzotiepina enantiomericamente enriquecidos
|
|
GB9800428D0
(en)
|
1998-01-10 |
1998-03-04 |
Glaxo Group Ltd |
Chemical compounds
|
|
EP2433623A1
(en)
|
1998-02-02 |
2012-03-28 |
Trustees Of Tufts College |
Use of dipeptidylpeptidase inhibitors to regulate glucose metabolism
|
|
US6221897B1
(en)
*
|
1998-06-10 |
2001-04-24 |
Aventis Pharma Deutschland Gmbh |
Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
|
|
DE19825804C2
(de)
|
1998-06-10 |
2000-08-24 |
Aventis Pharma Gmbh |
1,4-Benzothiepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
|
|
JP2000026300A
(ja)
|
1998-07-02 |
2000-01-25 |
Pola Chem Ind Inc |
血管内皮細胞保護医薬組成物
|
|
EP1103552A4
(en)
|
1998-08-07 |
2003-01-15 |
Takeda Chemical Industries Ltd |
BENZOTHIEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
|
|
US6096780A
(en)
|
1998-08-20 |
2000-08-01 |
Takeda Chemical Industries, Ltd. |
Quaternary ammonium salts and their use
|
|
DE19845405C2
(de)
|
1998-10-02 |
2000-07-13 |
Aventis Pharma Gmbh |
Arylsubstituierte Propanolaminderivate und deren Verwendung
|
|
DE19845406C2
(de)
|
1998-10-02 |
2001-10-18 |
Aventis Pharma Gmbh |
Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
DE19845403B4
(de)
|
1998-10-02 |
2005-02-10 |
Aventis Pharma Deutschland Gmbh |
Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
WO2000035889A1
(en)
|
1998-12-11 |
2000-06-22 |
Sankyo Company, Limited |
Substituted benzylamines
|
|
AU1690100A
(en)
|
1998-12-21 |
2000-07-12 |
Takeda Chemical Industries Ltd. |
Benzothiepin-anilide derivatives, their production and their use for antagonizing ccr-5
|
|
CA2356156A1
(en)
|
1998-12-23 |
2000-07-06 |
G.D. Searle Llc |
Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications
|
|
CA2356607A1
(en)
|
1998-12-23 |
2000-07-06 |
G.D. Searle Llc |
Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications
|
|
ATE241386T1
(de)
|
1998-12-23 |
2003-06-15 |
Searle Llc |
Kombinationen von ileumgallensäuretransports inhibitoren und cholesteryl ester transfer protein inhibitoren
|
|
EP1354604A1
(en)
|
1998-12-23 |
2003-10-22 |
G.D. Searle LLC. |
Combinations for cardiovascular indications
|
|
KR20020000139A
(ko)
|
1999-02-12 |
2002-01-04 |
추후제출 |
회장 담즙산 수송 및 타우로콜산염 흡수의 억제제로서의활성을 보유하는 신규한 1,2-벤조티아제핀
|
|
DE19916108C1
(de)
|
1999-04-09 |
2001-01-11 |
Aventis Pharma Gmbh |
Mit Zuckerresten substituierte 1,4-Benzothiazepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
|
|
SE9901387D0
(sv)
*
|
1999-04-19 |
1999-04-19 |
Astra Ab |
New pharmaceutical foromaulations
|
|
US6309663B1
(en)
|
1999-08-17 |
2001-10-30 |
Lipocine Inc. |
Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
|
|
CZ290178B6
(cs)
|
1999-07-22 |
2002-06-12 |
Sankyo Company Limited |
Deriváty cyklobutenu
|
|
WO2001020331A1
(en)
|
1999-09-14 |
2001-03-22 |
Xenoport, Inc. |
Substrates and screening methods for transport proteins
|
|
WO2001034570A1
(en)
|
1999-11-08 |
2001-05-17 |
Sankyo Company, Limited |
Nitrogenous heterocycle derivatives
|
|
WO2001052823A2
(en)
*
|
2000-01-20 |
2001-07-26 |
Noven Pharmaceuticals, Inc. |
Compositions to effect the release profile in the transdermal administration of drugs
|
|
EP1741445B1
(en)
|
2000-01-21 |
2013-08-14 |
Novartis AG |
Combinations comprising dipeptidylpeptidase-IV inhibitors and antidiabetic agents
|
|
SE0000772D0
(sv)
|
2000-03-08 |
2000-03-08 |
Astrazeneca Ab |
Chemical compounds
|
|
AU2001247331A1
(en)
|
2000-03-10 |
2001-09-24 |
Pharmacia Corporation |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
|
HK1052183A1
(zh)
|
2000-03-10 |
2003-09-05 |
Pharmacia Corporation |
制造tetrahydrobenzothiepines的方法
|
|
WO2001077325A1
(fr)
|
2000-04-12 |
2001-10-18 |
Takeda Chemical Industries, Ltd. |
Nouvelle proteine de recepteur couple aux proteines g et adn de celle-ci
|
|
US20020183307A1
(en)
|
2000-07-26 |
2002-12-05 |
Tremont Samuel J. |
Novel 1,4-benzothiazephine and 1,5-benzothiazepine compounds as inhibitors of apical sodium co-dependent bile acid transport and taurocholate uptake
|
|
NZ523684A
(en)
|
2000-07-28 |
2005-04-29 |
F |
New pharmaceutical composition
|
|
SE0003766D0
(sv)
|
2000-10-18 |
2000-10-18 |
Astrazeneca Ab |
Novel formulation
|
|
DE60142079D1
(de)
|
2000-11-17 |
2010-06-17 |
Banyu Pharma Co Ltd |
Verfahren zur suche nach komponenten, in dem das guanosintriphosphat- (gtp-) bindungsprotein gekoppeltes rezeptorprotein bg37 verwendet wird
|
|
WO2002050027A1
(de)
|
2000-12-21 |
2002-06-27 |
Aventis Pharma Deutschland Gmbh |
Neue diphenzylazetidinone, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung zur behandlung von lipidstoffwechselstörungen
|
|
EG26979A
(en)
|
2000-12-21 |
2015-03-01 |
Astrazeneca Ab |
Chemical compounds
|
|
JP2004517920A
(ja)
|
2001-01-26 |
2004-06-17 |
シェーリング コーポレイション |
血管状態を治療するためのステロール吸収阻害剤と血液調整剤との組合せ
|
|
WO2002078625A2
(en)
|
2001-03-28 |
2002-10-10 |
Pharmacia Corporation |
Therapeutic combinations for cardiovascular and inflammatory indications
|
|
EA200400029A1
(ru)
|
2001-07-19 |
2004-08-26 |
Фармация Корпорейшн |
КОМБИНАЦИЯ АНТАГОНИСТА РЕЦЕПТОРА АЛЬДОСТЕРОНА И ИНГИБИТОРА ГМГ-КоА-РЕДУКТАЗЫ
|
|
NZ531293A
(en)
|
2001-08-22 |
2005-08-26 |
Aventis Pharma Gmbh |
Pharamceuticals containing 1,4-benzothiepine-1,1-dioxide derivatives and another active substances such as ezetimibe, pamaqueside or tiqueside for treating lipid metabolism and atherosclerotic disorders
|
|
GB0121337D0
(en)
|
2001-09-04 |
2001-10-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0121621D0
(en)
|
2001-09-07 |
2001-10-31 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0121622D0
(en)
|
2001-09-07 |
2001-10-31 |
Astrazeneca Ab |
Chemical compounds
|
|
RU2305681C2
(ru)
|
2001-09-08 |
2007-09-10 |
Астразенека Аб |
Производные бензотиадиазепина, способ их получения (варианты)
|
|
WO2003022861A1
(en)
|
2001-09-13 |
2003-03-20 |
Bristol-Myers Squibb Company |
Process for the preparation of rebeccamycin and analogs thereof
|
|
AU2002336609B2
(en)
|
2001-09-21 |
2006-08-24 |
Merck Sharp & Dohme Corp. |
Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors
|
|
WO2003028632A2
(en)
|
2001-10-01 |
2003-04-10 |
Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The |
Development of a preventive vaccine for filovirus infection in primates
|
|
BR0213501A
(pt)
|
2001-11-02 |
2004-08-24 |
Searle Llc |
Compostos de benzotiepina mono- e di-fluorada como inibidores de transporte de ácido biliar co-dependente de sódio apical (asbt) e captação de taurocolato
|
|
AU2003207431A1
(en)
|
2002-01-17 |
2003-09-02 |
Pharmacia Corporation |
Novel alkyl/aryl hydroxy or keto thiepines.
|
|
GB0201850D0
(en)
|
2002-01-26 |
2002-03-13 |
Astrazeneca Ab |
Therapeutic treatment
|
|
US20040014806A1
(en)
|
2002-03-08 |
2004-01-22 |
Pharmacia Corporation |
Methods and compositions for lowering levels of blood lipids
|
|
US6987121B2
(en)
*
|
2002-04-25 |
2006-01-17 |
Smithkline Beecham Corporation |
Compositions and methods for hepatoprotection and treatment of cholestasis
|
|
GB0209467D0
(en)
|
2002-04-25 |
2002-06-05 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2003099264A1
(en)
|
2002-05-23 |
2003-12-04 |
Umd, Inc. |
Compositions and method for transmucosal drug delivery and cryoprotection
|
|
GB0213669D0
(en)
|
2002-06-14 |
2002-07-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0215579D0
(en)
|
2002-07-05 |
2002-08-14 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0216321D0
(en)
|
2002-07-13 |
2002-08-21 |
Astrazeneca Ab |
Therapeutic treatment
|
|
CN100494185C
(zh)
*
|
2002-08-28 |
2009-06-03 |
旭化成制药株式会社 |
新型季铵化合物
|
|
US7312208B2
(en)
*
|
2002-08-28 |
2007-12-25 |
Asahi Kasei Pharma Corporation |
Quaternary ammonium compounds
|
|
JP2006508188A
(ja)
|
2002-11-06 |
2006-03-09 |
シェーリング コーポレイション |
脱髄の処置のためのコレステロール吸収インヒビター
|
|
US20040122033A1
(en)
|
2002-12-10 |
2004-06-24 |
Nargund Ravi P. |
Combination therapy for the treatment of obesity
|
|
FR2848452B1
(fr)
*
|
2002-12-12 |
2007-04-06 |
Aventis Pharma Sa |
Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer
|
|
US20040138145A1
(en)
|
2002-12-12 |
2004-07-15 |
Aventis Pharma S.A. |
Application of intestinal biliary acid reuptake inhibitors for the prevention and treatment of alzheimer's disease
|
|
US20040147774A1
(en)
|
2002-12-20 |
2004-07-29 |
Aventis Pharma S.A. |
Novel chiral compounds derived from hexanoic acid esters, preparation process and intermediates, use in the synthesis of chiral 2-(bromomethyl)-2-ethylhexanoic acid
|
|
US20050031651A1
(en)
|
2002-12-24 |
2005-02-10 |
Francine Gervais |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
GB0304194D0
(en)
|
2003-02-25 |
2003-03-26 |
Astrazeneca Ab |
Chemical compounds
|
|
US7192944B2
(en)
|
2003-03-07 |
2007-03-20 |
Schering Corp. |
Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
|
|
US7208486B2
(en)
|
2003-03-07 |
2007-04-24 |
Schering Corporation |
Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
|
|
GB0307918D0
(en)
|
2003-04-05 |
2003-05-14 |
Astrazeneca Ab |
Therapeutic use
|
|
JP2005044778A
(ja)
|
2003-07-19 |
2005-02-17 |
Samsung Sdi Co Ltd |
電界発光素子
|
|
JP2005097216A
(ja)
|
2003-09-26 |
2005-04-14 |
Kaneka Corp |
ＰＰＡＲγリガンド剤
|
|
CA2544309A1
(en)
|
2003-11-05 |
2005-05-26 |
Schering Corporation |
Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
|
|
EP1564554A1
(en)
|
2004-02-12 |
2005-08-17 |
Pepscan Systems B.V. |
Method for the detection of early B cell populations in vaccine development
|
|
US7973030B2
(en)
*
|
2004-02-27 |
2011-07-05 |
Asahi Kasei Pharma Corporation |
Benzothiazepine and benzothiepine compounds
|
|
DE102004016845A1
(de)
|
2004-04-07 |
2005-10-27 |
Bayer Healthcare Ag |
Phenylthioessigsäure-Derivate und ihre Verwendung
|
|
WO2006017257A2
(en)
|
2004-07-12 |
2006-02-16 |
Phenomix Corporation |
Azetidinone derivatives
|
|
JP2008513465A
(ja)
|
2004-09-15 |
2008-05-01 |
ザ プレジデント アンド フェロウズ オブ ハーバード カレッジ |
肥満及び糖尿病の治療におけるｅｒストレス低減
|
|
DE102004046623A1
(de)
|
2004-09-25 |
2006-03-30 |
Bayer Healthcare Ag |
Neue Pyrimidin-Derivate und ihre Verwendung
|
|
WO2006039334A1
(en)
|
2004-09-29 |
2006-04-13 |
Schering Corporation |
Combinations of substituted azetidonones and cb1 antagonists
|
|
EP1810689A4
(en)
|
2004-10-15 |
2009-07-22 |
Mitsubishi Tanabe Pharma Corp |
MEANS FOR THE PREVENTION AND / OR TREATMENT OF DIABETES
|
|
MX2007004934A
(es)
|
2004-10-25 |
2007-06-12 |
Novartis Ag |
Combinacion de inhibidor de dpp-iv, anti-diabetico de ppar, y metformina.
|
|
AU2004325203A1
(en)
|
2004-11-24 |
2006-06-01 |
Seo Hong Yoo |
Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof
|
|
DE102004058062A1
(de)
|
2004-12-02 |
2006-06-08 |
Bayer Healthcare Ag |
Cyclische Iminocarbamate und ihre Verwendung
|
|
CN102633730A
(zh)
|
2004-12-03 |
2012-08-15 |
先灵公司 |
作为cb1拮抗剂的取代哌嗪
|
|
US20070032420A1
(en)
|
2005-02-09 |
2007-02-08 |
Entelos, Inc. |
Treating diabetes with glucagon-like peptide-1 secretagogues
|
|
US20060193895A1
(en)
|
2005-02-25 |
2006-08-31 |
Use-Techno Corporation |
Additive for food and beverage, pharmaceutical composition, GLUT4 translocator, and method for translocating GLUT4
|
|
DE102005027150A1
(de)
|
2005-03-12 |
2006-09-28 |
Bayer Healthcare Ag |
Pyrimidincarbonsäure-Derivate und ihre Verwendung
|
|
FR2883284A1
(fr)
|
2005-03-15 |
2006-09-22 |
Commissariat Energie Atomique |
Nouveaux derives dihydropyrimidines et leur utilisation comme agents anti-cancereux
|
|
UY29445A1
(es)
|
2005-03-30 |
2006-10-02 |
Generex Pharm Inc |
Composiciones para la transmisión transmucosa oral de la metformina
|
|
US20080031968A1
(en)
|
2005-04-01 |
2008-02-07 |
The Brigham And Women's Hospital, Inc. |
Methods for increasing cellular energy expenditure
|
|
EP1874330A2
(en)
|
2005-04-04 |
2008-01-09 |
Julius-Maximilians-Universität Würzburg |
Peptides that down regulate the activity of plasma membrane transporters including sodium-d-glucose cotransporter sglt1
|
|
WO2006105913A1
(en)
|
2005-04-04 |
2006-10-12 |
Julius-Maximillians-Universität Würzburg |
Tripeptides that down regulate the activity of plasma membrane transporters including sodium-d-glucose cotransporter sglt1
|
|
EP1877067A1
(en)
|
2005-04-26 |
2008-01-16 |
Microbia, Inc. |
4-biarylyl-1-phenylazetidin-2-one glucuronide derivatives for hypercholesterolemia
|
|
DE102005020229A1
(de)
|
2005-04-30 |
2006-11-09 |
Bayer Healthcare Ag |
Verwendung von Indolin-Phenylsulfonamid-Derivaten
|
|
US20090074895A1
(en)
|
2005-05-02 |
2009-03-19 |
Vanadis Bioscience Ltd |
Composition and uses thereof
|
|
US20090131395A1
(en)
|
2005-05-05 |
2009-05-21 |
Microbia, Inc. |
Biphenylazetidinone cholesterol absorption inhibitors
|
|
WO2006122186A2
(en)
|
2005-05-10 |
2006-11-16 |
Microbia, Inc. |
1,4-diphenyl-3-hydroxyalkyl-2-azetidinone derivatives for treating hypercholestrolemia
|
|
WO2006124713A2
(en)
|
2005-05-13 |
2006-11-23 |
Microbia, Inc. |
4-biarylyl-1-phenylazetidin-2-ones
|
|
SMAP200700061A
(it)
*
|
2005-05-31 |
2007-12-28 |
Novartis Ag |
Trattamento delle malattie epatiche in cui il ferro svolge un ruolo nella patogenesi
|
|
DE102005033099A1
(de)
|
2005-07-15 |
2007-01-18 |
Sanofi-Aventis Deutschland Gmbh |
Neues 1,4-Benzothiazepin-1,1-Dioxidderivat mit verbesserten Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindung enthaltende Arzneimittel und dessen Verwendung
|
|
US20070025953A1
(en)
|
2005-07-27 |
2007-02-01 |
Jones Michael R |
Co-therapy for diabetic conditions
|
|
WO2007035703A1
(en)
|
2005-09-20 |
2007-03-29 |
Schering Corporation |
1- [ [1- [ (2-amin0-6-methyl-4-pyridinyl) methyl] -4-flu0r0-4-piperidinyl,] carbonyl] -4- [2- (2-pyridinyl) -3h-imidaz0 [4 , 5-b] pyridin-3-yl] piperidine useful as histamine h3 antagonist
|
|
AU2006297130B2
(en)
|
2005-09-30 |
2009-12-24 |
Novartis Ag |
DPP IV inhibitor for use in the treatment of autoimmune diseases and graft rejection
|
|
EP1948280A4
(en)
|
2005-10-24 |
2011-07-06 |
Andrew Young |
BILARY / PANCREATIC DERIVATION DEVICE AND METHOD FOR THE TREATMENT OF METABOLIC DISEASES AND OTHER DISEASES
|
|
US7705028B2
(en)
|
2005-12-19 |
2010-04-27 |
Glaxosmithkline Llc |
Farnesoid X receptor agonists
|
|
CA2634940A1
(en)
|
2005-12-21 |
2007-07-05 |
Schering Corporation |
Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and h3 receptor antagonist/inverse agonist
|
|
JP2009525954A
(ja)
|
2006-01-13 |
2009-07-16 |
シェーリング コーポレイション |
Ｃｂ１モジュレーターとしてのジアリールピペリジン
|
|
BRPI0706623A2
(pt)
|
2006-01-18 |
2011-04-12 |
Schering Corp |
moduladores de receptor canabinóide
|
|
AU2007243131A1
(en)
|
2006-01-20 |
2007-11-08 |
Smithkline Beecham Corporation |
Use of sulfonamide derivatives in the treatment of disorders of the metabolism and the nervous system
|
|
JP2010517931A
(ja)
|
2006-02-14 |
2010-05-27 |
インターセプト ファーマシューティカルズ， インコーポレイテッド |
Ｆｘｒ媒介性の疾患または状態の予防または治療用のｆｘｒリガンドとしての胆汁酸誘導体
|
|
DE102006009813A1
(de)
|
2006-03-01 |
2007-09-06 |
Bayer Healthcare Ag |
Verwendung von A2b/A1 Rezeptor Agonisten zur Modulation der Lipidspiegel
|
|
WO2007123949A2
(en)
|
2006-04-21 |
2007-11-01 |
Schering Corporation |
Cannabinoid receptor modulators
|
|
DE102006024024A1
(de)
|
2006-05-23 |
2007-11-29 |
Bayer Healthcare Aktiengesellschaft |
Substituierte Arylimidazolone und -triazolone sowie ihre Verwendung
|
|
DE102006026585A1
(de)
|
2006-06-07 |
2007-12-13 |
Bayer Healthcare Aktiengesellschaft |
Substituierte 4-Aryl-1,4-dihydro-1,6-naphthyridine und ihre Verwendung
|
|
DE102006026583A1
(de)
|
2006-06-07 |
2007-12-13 |
Bayer Healthcare Aktiengesellschaft |
Aryl-substituierte hetero-bicyclische Verbindungen und ihre Verwendung
|
|
CA2656320C
(en)
|
2006-06-27 |
2015-04-28 |
Intercept Pharmaceuticals, Inc. |
Bile acid derivatives as fxr ligands for the prevention or treatment of fxr-mediated diseases or conditions
|
|
WO2008028037A2
(en)
|
2006-08-30 |
2008-03-06 |
Andrew Young |
Distender device and method for treatment of obesity and metabolic and other diseases
|
|
DE102006042143A1
(de)
|
2006-09-08 |
2008-03-27 |
Bayer Healthcare Aktiengesellschaft |
Neue substituierte Bipyridin-Derivate und ihre Verwendung
|
|
DE102006043520A1
(de)
|
2006-09-12 |
2008-03-27 |
Bayer Healthcare Ag |
2-Phenoxynikotinsäure-Derivate und ihre Verwendung
|
|
DE102006043519A1
(de)
|
2006-09-12 |
2008-03-27 |
Bayer Healthcare Ag |
4-Phenoxynikotinsäure-Derivate und ihre Verwendung
|
|
WO2008033431A1
(en)
|
2006-09-15 |
2008-03-20 |
Schering Corporation |
Spirocyclic azetidinone derivatives for the treatment of disorders of lipid metabolism, pain, diabetes and other disorders
|
|
CA2663500A1
(en)
|
2006-09-15 |
2008-03-20 |
Schering Corporation |
Spiro-condensed azetidine derivatives useful in treating pain, diabetes and disorders of lipid metabolism
|
|
WO2008033468A2
(en)
|
2006-09-15 |
2008-03-20 |
Schering Corporation |
Azetidine and azetidone derivatives useful in treating pain and disorders of lipid metabolism
|
|
US20080070984A1
(en)
|
2006-09-15 |
2008-03-20 |
Tran Pierre V |
Compositions and Methods of Treating Schizophrenia
|
|
CN101528227A
(zh)
|
2006-09-15 |
2009-09-09 |
先灵公司 |
氮杂环丁酮衍生物及其使用方法
|
|
CA2663947A1
(en)
|
2006-09-15 |
2008-03-20 |
Schering Corporation |
Azetidine and azetidone derivatives useful in treating pain and disorders of lipid metabolism
|
|
CA2663502A1
(en)
|
2006-09-15 |
2008-03-20 |
Schering Corporation |
Azetidinone derivatives and methods of use thereof
|
|
WO2008033460A2
(en)
|
2006-09-15 |
2008-03-20 |
Schering Corporation |
Treating pain, diabetes, and lipid metabolism disorders
|
|
DE102006044696A1
(de)
|
2006-09-22 |
2008-03-27 |
Bayer Healthcare Ag |
3-Cyano-5-thiazaheteroaryl-dihydropyridine und ihre Verwendung
|
|
WO2008039829A2
(en)
|
2006-09-26 |
2008-04-03 |
Ironwood Pharmaceuticals, Inc. |
Diphenylheterocycle cholesterol absorption inhibitors
|
|
CL2007003035A1
(es)
|
2006-10-24 |
2008-05-16 |
Smithkline Beechman Corp |
Compuestos derivados de isoxazol sustituidos, agonistas de receptores farnesoid x; procedimiento de preparacion; composicion farmaceutica que lo comprende; y uso del compuesto en el tratamiento de la obesidad, diabetes mellitus, fibrosis en organos,
|
|
US20080161400A1
(en)
|
2006-10-26 |
2008-07-03 |
Xenoport, Inc. |
Use of forms of propofol for treating diseases associated with oxidative stress
|
|
DE102006053635B4
(de)
*
|
2006-11-14 |
2011-06-30 |
Sanofi-Aventis Deutschland GmbH, 65929 |
Neue mit Benzylresten substituierte 1,4-Benzothiepin-1,1-Dioxidderivate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
DE102006053637B4
(de)
*
|
2006-11-14 |
2011-06-30 |
Sanofi-Aventis Deutschland GmbH, 65929 |
Neue mit Fluor substituierte 1,4-Benzothiepin-1,1-Dioxidderivate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
EP2083832B1
(de)
|
2006-11-14 |
2011-01-05 |
Sanofi-Aventis Deutschland GmbH |
Neue 1,4-benzothiepin-1,1-dioxidderivate mit verbesserten eigenschaften, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2008067219A2
(en)
|
2006-11-29 |
2008-06-05 |
Kalypsys, Inc. |
Quinazolinone modulators of tgr5
|
|
DE102006056740A1
(de)
|
2006-12-01 |
2008-06-05 |
Bayer Healthcare Ag |
Cyclisch substituierte 3,5-Dicyano-2-thiopyridine und ihre Verwendung
|
|
DE102006056739A1
(de)
|
2006-12-01 |
2008-06-05 |
Bayer Healthcare Ag |
Substituierte 4-Amino-3,5-dicyano-2-thiopyridine und ihre Verwendung
|
|
WO2008088836A2
(en)
|
2007-01-16 |
2008-07-24 |
The Burnham Institute For Medical Research |
Compositions and methods for treatment of colorectal cancer
|
|
US8410083B2
(en)
|
2007-01-19 |
2013-04-02 |
Intercept Pharmaceuticals, Inc. |
23-substituted bile acids as TGR5 modulators and methods of use thereof
|
|
WO2008097976A1
(en)
|
2007-02-09 |
2008-08-14 |
Kalypsys, Inc. |
Heterocyclic modulators of tgr5 for treatment of disease
|
|
DE102007009494A1
(de)
|
2007-02-27 |
2008-08-28 |
Bayer Healthcare Ag |
Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
|
|
US20100144864A1
(en)
|
2007-04-05 |
2010-06-10 |
Ironwood Pharmaceuticals, Inc. |
Soluble guanylate cyclase (sgc) modulators for treatment of lipid related disorders
|
|
WO2008130616A2
(en)
|
2007-04-19 |
2008-10-30 |
Schering Corporation |
Diaryl morpholines as cb1 modulators
|
|
AU2008288770B2
(en)
|
2007-08-23 |
2014-06-12 |
Theracosbio, Llc |
Benzylbenzene derivatives and methods of use
|
|
WO2009115398A1
(en)
*
|
2008-03-18 |
2009-09-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Vitamin d compounds for the treatment of biliary diseases
|
|
EP2108960A1
(en)
|
2008-04-07 |
2009-10-14 |
Arena Pharmaceuticals, Inc. |
Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
|
|
AU2009276507B2
(en)
|
2008-07-30 |
2015-11-19 |
Intercept Pharmaceuticals, Inc. |
TGR5 modulators and methods of use thereof
|
|
CA2744189C
(en)
|
2008-11-19 |
2016-10-11 |
Intercept Pharmaceuticals, Inc. |
Tgr5 modulators and methods of use thereof
|
|
CA2744697C
(en)
|
2008-11-26 |
2016-06-21 |
Satiogen Pharmaceuticals, Inc. |
Use of compositions comprising bile acids, salts, and mimics thereof for the treatment of obesity or diabetes
|
|
JP2012509891A
(ja)
*
|
2008-11-26 |
2012-04-26 |
サティオゲン ファーマシューティカルズ，インク． |
肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤
|
|
US20110065676A1
(en)
|
2009-06-24 |
2011-03-17 |
Schering Corporation |
Combination therapies comprising par1 antagonists with nar agonists
|
|
BR112012004284B8
(pt)
|
2009-08-25 |
2021-05-25 |
Ahab Sheps Jonathan |
ácidos biliares poli-hidroxilados para tratamento de transtornos biliares
|
|
WO2011075539A2
(en)
*
|
2009-12-18 |
2011-06-23 |
Satiogen Pharmaceuticals, Inc. |
Treatment of obesity or diabetes with bile acid sequestrants
|
|
EP2995317A1
(en)
*
|
2010-05-26 |
2016-03-16 |
Satiogen Pharmaceuticals, Inc. |
Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
|
|
RS57778B1
(sr)
*
|
2010-11-04 |
2018-12-31 |
Albireo Ab |
Inhibitori crevnog transportera žučne kiseline (ibat) za lečenje bolesti jetre
|
|
EP2637667A4
(en)
|
2010-11-08 |
2014-06-25 |
Albireo Ab |
IBAT HEMMER FOR THE TREATMENT OF METABOLISM DISEASES AND RELATED ACCIDENTS
|
|
US20120114588A1
(en)
|
2010-11-08 |
2012-05-10 |
Albireo Ab |
Ibat inhibitors for treatment of metabolic disorders and related conditions
|
|
KR101890960B1
(ko)
|
2010-11-08 |
2018-09-28 |
알비레오 에이비 |
Ⅰｂａｔ 억제제 및 담즙산 바인더를 포함하는 약학적 조합물
|
|
KR102051031B1
(ko)
|
2011-10-28 |
2019-12-02 |
루메나 파마수티컬즈, 인코포레이티드 |
고담혈증 및 담즙 정체성 간 질환 치료용 담즙산 재순환 억제제
|
|
EP2771003B1
(en)
|
2011-10-28 |
2017-04-19 |
Lumena Pharmaceuticals LLC |
Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
|
|
US9007272B2
(en)
|
2012-07-19 |
2015-04-14 |
Tensorcom, Inc. |
Method and apparatus for the alignment of a 60 GHz endfire antenna
|
|
MX2015013193A
(es)
|
2013-03-15 |
2016-04-15 |
Lumena Pharmaceuticals Inc |
Inhibidores del reciclaje de acidos biliares para el tratamiento de colangitis esclerosante primaria y enfermedad inflamatoria intestinal.
|
|
DK3435996T3
(da)
|
2016-03-31 |
2025-07-21 |
Genfit |
Elafibranor til anvendelse i behandlingen af primær biliær cholangitis
|
|
SG11201909168VA
(en)
|
2017-04-18 |
2019-11-28 |
Genfit |
Combination comprising a ppar agonist such as elafibranor and an acetyl-coa carboxylase (acc) inhibitor
|