JP2024536126A5 - - Google Patents

Info

Publication number
JP2024536126A5
JP2024536126A5 JP2024519112A JP2024519112A JP2024536126A5 JP 2024536126 A5 JP2024536126 A5 JP 2024536126A5 JP 2024519112 A JP2024519112 A JP 2024519112A JP 2024519112 A JP2024519112 A JP 2024519112A JP 2024536126 A5 JP2024536126 A5 JP 2024536126A5
Authority
JP
Japan
Prior art keywords
subject
resmethirome
pharmaceutical composition
composition according
approximately
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024519112A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024536126A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/044826 external-priority patent/WO2023049491A1/en
Publication of JP2024536126A publication Critical patent/JP2024536126A/ja
Publication of JP2024536126A5 publication Critical patent/JP2024536126A5/ja
Pending legal-status Critical Current

Links

JP2024519112A 2021-09-27 2022-09-27 肝体積を減少させるためのレスメチロム Pending JP2024536126A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163248634P 2021-09-27 2021-09-27
US63/248,634 2021-09-27
PCT/US2022/044826 WO2023049491A1 (en) 2021-09-27 2022-09-27 Resmetirom for reducing liver volume

Publications (2)

Publication Number Publication Date
JP2024536126A JP2024536126A (ja) 2024-10-04
JP2024536126A5 true JP2024536126A5 (enExample) 2026-06-25

Family

ID=83900064

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024519112A Pending JP2024536126A (ja) 2021-09-27 2022-09-27 肝体積を減少させるためのレスメチロム

Country Status (13)

Country Link
US (2) US20240408102A1 (enExample)
EP (2) EP4578499A3 (enExample)
JP (1) JP2024536126A (enExample)
KR (1) KR20240073926A (enExample)
CN (1) CN118251221A (enExample)
AR (1) AR127165A1 (enExample)
AU (1) AU2022348966A1 (enExample)
CA (1) CA3233319A1 (enExample)
CL (1) CL2024000886A1 (enExample)
IL (1) IL311670A (enExample)
MX (1) MX2024003967A (enExample)
TW (1) TW202337470A (enExample)
WO (1) WO2023049491A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024251233A1 (zh) * 2023-06-08 2024-12-12 成都微芯药业有限公司 PPAR全激动剂联合THR-β激动剂在抗代谢相关疾病中的用途
JP2026521649A (ja) * 2023-06-22 2026-06-30 マドリガル ファーマシューティカルズ インコーポレイテッド THR-βアゴニストを用いて肝障害を治療するためのバイオマーカーおよび関連する使用
KR20260000642A (ko) * 2024-06-25 2026-01-05 연세대학교 산학협력단 Usp10 억제제를 유효성분으로 포함하는, 간섬유증 또는 간섬유증 관련 질환의 예방 또는 치료용 조성물
WO2026107045A1 (en) * 2024-11-12 2026-05-21 Madrigal Pharmaceuticals, Inc. Resmetirom for use in treating cardiomyopathy and/or related heart failure and portal hypertension

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE480524T1 (de) 2005-07-21 2010-09-15 Hoffmann La Roche Pyridazinonderivate als schilddrüsenhormon- rezeptoragonisten
US8076334B2 (en) 2007-09-20 2011-12-13 Hoffmann-La Roche Inc. Prodrugs of thyroid hormone analogs
ES2795450T3 (es) 2012-09-17 2020-11-23 Madrigal Pharmaceuticals Inc Procedimiento para sintetizar análogos de hormonas tiroideas y polimorfos de los mismos
MX394463B (es) 2016-10-18 2025-03-19 Madrigal Pharmaceuticals Inc Métodos para tratar trastornos del hígado o trastornos lipídicos con un agonista de thr-beta.
TW202615431A (zh) 2018-07-02 2026-04-16 美商瑪德瑞高製藥公司 2-(3,5-二氯-4-((5-異丙基-6-側氧基-1,6-二氫噠嗪-3-基)氧)苯基)-3,5-二側氧基-2,3,4,5-四氫-1,2,4-三嗪-6-腈之固體型式
CA3111025C (en) * 2018-09-06 2023-10-31 Galmed Research And Development Ltd Combination therapy for the treatment of liver disease
EP4775207A2 (en) 2018-12-05 2026-07-15 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis
CA3195960A1 (en) 2020-10-23 2022-04-28 Madrigal Pharmaceuticals, Inc. Process for the preparation of 6-(4-nitro-phenoxy)-2h-pyridazin-3-one and 6-(4-amino-phenoxy)-2h-pyridazin-3-one derivatives as intermediates of thyroid hormone analogues

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