JP2013533858A5 - - Google Patents
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- JP2013533858A5 JP2013533858A5 JP2013513388A JP2013513388A JP2013533858A5 JP 2013533858 A5 JP2013533858 A5 JP 2013533858A5 JP 2013513388 A JP2013513388 A JP 2013513388A JP 2013513388 A JP2013513388 A JP 2013513388A JP 2013533858 A5 JP2013533858 A5 JP 2013533858A5
- Authority
- JP
- Japan
- Prior art keywords
- tnfα antibody
- use according
- subject
- weeks
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 206010000269 abscess Diseases 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 229940127249 oral antibiotic Drugs 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 229960002964 adalimumab Drugs 0.000 claims 3
- 238000002360 preparation method Methods 0.000 claims 3
- 210000000106 sweat gland Anatomy 0.000 claims 3
- 238000011287 therapeutic dose Methods 0.000 claims 3
- 230000003442 weekly effect Effects 0.000 claims 3
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 230000003902 lesion Effects 0.000 claims 2
- 206010016717 Fistula Diseases 0.000 claims 1
- 210000003484 anatomy Anatomy 0.000 claims 1
- 230000003890 fistula Effects 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35112510P | 2010-06-03 | 2010-06-03 | |
| US61/351,125 | 2010-06-03 | ||
| US201161430645P | 2011-01-07 | 2011-01-07 | |
| US61/430,645 | 2011-01-07 | ||
| US201161474764P | 2011-04-13 | 2011-04-13 | |
| US61/474,764 | 2011-04-13 | ||
| PCT/US2011/039135 WO2011153477A2 (en) | 2010-06-03 | 2011-06-03 | Uses and compositions for treatment of hidradenitis suppurativa (hs) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016103023A Division JP2016193916A (ja) | 2010-06-03 | 2016-05-24 | 汗腺膿瘍（ｈｓ）の治療のための使用および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013533858A JP2013533858A (ja) | 2013-08-29 |
| JP2013533858A5 true JP2013533858A5 (enExample) | 2014-07-24 |
| JP5944382B2 JP5944382B2 (ja) | 2016-07-05 |
Family
ID=45064648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013513388A Active JP5944382B2 (ja) | 2010-06-03 | 2011-06-03 | 汗腺膿瘍（ｈｓ）の治療のための使用および組成物 |
| JP2016103023A Pending JP2016193916A (ja) | 2010-06-03 | 2016-05-24 | 汗腺膿瘍（ｈｓ）の治療のための使用および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016103023A Pending JP2016193916A (ja) | 2010-06-03 | 2016-05-24 | 汗腺膿瘍（ｈｓ）の治療のための使用および組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US8747854B2 (enExample) |
| EP (1) | EP2575884B1 (enExample) |
| JP (2) | JP5944382B2 (enExample) |
| CN (2) | CN105056232A (enExample) |
| CA (1) | CA2801917C (enExample) |
| CY (1) | CY1120664T1 (enExample) |
| DK (1) | DK2575884T3 (enExample) |
| ES (1) | ES2685607T3 (enExample) |
| HR (1) | HRP20181598T1 (enExample) |
| HU (1) | HUE039740T2 (enExample) |
| LT (1) | LT2575884T (enExample) |
| MX (1) | MX2012014080A (enExample) |
| PL (1) | PL2575884T3 (enExample) |
| PT (1) | PT2575884T (enExample) |
| RS (1) | RS57543B1 (enExample) |
| SI (1) | SI2575884T1 (enExample) |
| SM (1) | SMT201800428T1 (enExample) |
| WO (1) | WO2011153477A2 (enExample) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| WO1997029131A1 (en) | 1996-02-09 | 1997-08-14 | Basf Aktiengesellschaft | HUMAN ANTIBODIES THAT BIND HUMAN TNF$g(a) |
| CA2817619A1 (en) | 2001-06-08 | 2002-12-08 | Abbott Laboratories (Bermuda) Ltd. | Methods of administering anti-tnf.alpha. antibodies |
| US20090280065A1 (en) * | 2006-04-10 | 2009-11-12 | Willian Mary K | Uses and Compositions for Treatment of Psoriasis |
| TW201705980A (zh) | 2004-04-09 | 2017-02-16 | 艾伯維生物技術有限責任公司 | 用於治療ＴＮＦα相關失調症之多重可變劑量療法 |
| GB0414054D0 (en) | 2004-06-23 | 2004-07-28 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
| CN102961746B (zh) | 2005-05-16 | 2016-06-15 | 艾伯维生物技术有限公司 | TNFα抑制剂治疗腐蚀性多关节炎的用途 |
| TWI424161B (zh) | 2005-11-01 | 2014-01-21 | Abbvie Biotechnology Ltd | 利用生物標記診斷關節黏連脊椎炎之方法及組合物 |
| NZ611859A (en) | 2006-04-05 | 2014-12-24 | Abbvie Biotechnology Ltd | Antibody purification |
| EP2010214A4 (en) * | 2006-04-10 | 2010-06-16 | Abbott Biotech Ltd | USES AND COMPOSITIONS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS |
| US9605064B2 (en) * | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
| EP2012586A4 (en) | 2006-04-10 | 2010-08-18 | Abbott Biotech Ltd | USES AND COMPOSITIONS FOR THE TREATMENT OF ANKYLOSANTE SPONDYLARTHRITIS |
| US20100021451A1 (en) | 2006-06-08 | 2010-01-28 | Wong Robert L | Uses and compositions for treatment of ankylosing spondylitis |
| TWI527603B (zh) | 2006-06-30 | 2016-04-01 | 艾伯維生物技術有限責任公司 | 自動注射裝置 |
| CA2667655A1 (en) | 2006-10-27 | 2008-05-15 | Abbott Biotechnology Ltd. | Crystalline anti-htnfalpha antibodies |
| EP2171451A4 (en) * | 2007-06-11 | 2011-12-07 | Abbott Biotech Ltd | METHOD FOR TREATING JUVENILIAN IDIOPATHIC ARTHRITIS |
| US20090110679A1 (en) * | 2007-07-13 | 2009-04-30 | Luk-Chiu Li | Methods and compositions for pulmonary administration of a TNFa inhibitor |
| JP2010535771A (ja) * | 2007-08-08 | 2010-11-25 | アボット・ラボラトリーズ | 抗体を結晶化させるための組成物及び方法 |
| NZ585702A (en) * | 2007-11-30 | 2013-08-30 | Abbott Lab | Protein formulations and methods of making same |
| US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
| CN105056232A (zh) * | 2010-06-03 | 2015-11-18 | 阿布维生物技术有限公司 | 用于治疗化脓性汗腺炎(hs)的用途和组合物 |
| US20110311547A1 (en) | 2010-06-18 | 2011-12-22 | Xbiotech, Inc. | Arthritis Treatment |
| KR20210128021A (ko) | 2010-08-23 | 2021-10-25 | 얀센 바이오테크 인코포레이티드 | 종양성 질병들에 대한 치료 |
| MX344727B (es) | 2010-11-11 | 2017-01-05 | Abbvie Biotechnology Ltd | Formulaciones liquidas de anticuerpos anti-tnf-alfa de alta concentracion mejoradas. |
| SG10201600576QA (en) | 2011-01-24 | 2016-02-26 | Abbvie Biotechnology Ltd | Automatic injection devices having overmolded gripping surfaces |
| WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
| US9150645B2 (en) | 2012-04-20 | 2015-10-06 | Abbvie, Inc. | Cell culture methods to reduce acidic species |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| AU2013309506A1 (en) | 2012-09-02 | 2015-03-12 | Abbvie Inc. | Methods to control protein heterogeneity |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
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| SG11201507230PA (en) | 2013-03-12 | 2015-10-29 | Abbvie Inc | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| US9499614B2 (en) | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
| US8921526B2 (en) | 2013-03-14 | 2014-12-30 | Abbvie, Inc. | Mutated anti-TNFα antibodies and methods of their use |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| WO2015051293A2 (en) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| JP6526025B2 (ja) | 2013-10-16 | 2019-06-05 | オンコバイオロジクス，インコーポレイティド | 抗体安定性を増強する緩衝液製剤 |
| US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| US10696735B2 (en) | 2015-01-21 | 2020-06-30 | Outlook Therapeutics, Inc. | Modulation of charge variants in a monoclonal antibody composition |
| EP3078675A1 (en) | 2015-04-10 | 2016-10-12 | Ares Trading S.A. | Induction dosing regimen for the treatment of tnf alpha mediated disorders |
| MX2018009341A (es) | 2016-02-03 | 2019-05-15 | Oncobiologics Inc | Formulaciones tamponadas para una mayor estabilidad de anticuerpos. |
| KR102435599B1 (ko) | 2016-06-02 | 2022-08-29 | 애브비 인코포레이티드 | 글루코코르티코이드 수용체 작용제 및 이의 면역접합체 |
| DK3538118T3 (da) | 2016-11-11 | 2021-05-25 | Sjaellands Univ Dermatologisk Afdeling | Levende saprofytbakterier til anvendelse til behandling af hidradenitis suppurativa |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| MX2019009798A (es) | 2017-02-16 | 2020-01-30 | Xbiotech Inc | Tratamiento de la hidradenitis supurativa. |
| US20200277369A1 (en) * | 2017-11-20 | 2020-09-03 | Novartis Ag | Method of treating hidradentitis suppurativa with il-17 antagonists |
| RS61994B1 (sr) | 2017-12-01 | 2021-07-30 | Abbvie Inc | Agonist glukokortikoidnog receptora i njegovi imunokonjugati |
| IL315310A (en) | 2017-12-26 | 2024-10-01 | Kymera Therapeutics Inc | Irak degraders and uses thereof |
| WO2019130215A1 (en) * | 2017-12-27 | 2019-07-04 | To Pharmaceuticals Llc | Cannabis compositions for the treatment of inflammatory skin disorders |
| BR112020016738A2 (pt) | 2018-03-14 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Uso de anticorpos anti-il-36r para o tratamento de psoríase pustular generalizada |
| TWI737000B (zh) * | 2018-10-22 | 2021-08-21 | 美商美國禮來大藥廠 | 用於治療化膿性汗腺炎之泛-ｅｌｒ＋ｃｘｃ趨化介素抗體 |
| US12251365B2 (en) | 2018-11-15 | 2025-03-18 | Abbvie Inc. | Pharmaceutical formulations for subcutaneous administration |
| SG11202105424PA (en) | 2018-11-30 | 2021-06-29 | Kymera Therapeutics Inc | Irak degraders and uses thereof |
| BR112022025728A2 (pt) * | 2020-06-17 | 2023-01-03 | Kymera Therapeutics Inc | Agentes de degradação de irak e usos dos mesmos |
| WO2022015920A1 (en) | 2020-07-17 | 2022-01-20 | Boehringer Ingelheim International Gmbh | Anti-il-36r antibodies for the treatment of neutrophilic dermatoses |
| WO2022117569A1 (en) | 2020-12-02 | 2022-06-09 | Oncurious Nv | A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer |
| MX2023007852A (es) | 2020-12-30 | 2023-07-07 | Kymera Therapeutics Inc | Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos. |
| IL304905A (en) | 2021-02-15 | 2023-10-01 | Kymera Therapeutics Inc | IRAK4 joints and their uses |
| EP4359436A1 (en) * | 2021-06-22 | 2024-05-01 | Novartis AG | Bispecific antibodies for use in treatment of hidradenitis suppurativa |
| WO2023076556A1 (en) | 2021-10-29 | 2023-05-04 | Kymera Therapeutics, Inc. | Irak4 degraders and synthesis thereof |
| IL314437A (en) | 2022-01-31 | 2024-09-01 | Kymera Therapeutics Inc | IRAK joints and their uses |
| KR20250031013A (ko) * | 2023-08-23 | 2025-03-06 | (주)셀트리온 | TNFα 관련 질환을 치료하는 방법 |
| WO2025147499A1 (en) * | 2024-01-03 | 2025-07-10 | Abbvie Inc. | Lutikizumab for use in a treatment of hidradenitis suppurativa |
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