JP2020521797A5 - - Google Patents
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- JP2020521797A5 JP2020521797A5 JP2019566199A JP2019566199A JP2020521797A5 JP 2020521797 A5 JP2020521797 A5 JP 2020521797A5 JP 2019566199 A JP2019566199 A JP 2019566199A JP 2019566199 A JP2019566199 A JP 2019566199A JP 2020521797 A5 JP2020521797 A5 JP 2020521797A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutical composition
- seq
- treatment
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17174323.0 | 2017-06-02 | ||
| EP17174323 | 2017-06-02 | ||
| EP17196949 | 2017-10-17 | ||
| EP17196949.6 | 2017-10-17 | ||
| PCT/EP2018/064445 WO2018220169A1 (en) | 2017-06-02 | 2018-06-01 | Anti-cancer combination therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020521797A JP2020521797A (ja) | 2020-07-27 |
| JP2020521797A5 true JP2020521797A5 (enExample) | 2021-07-26 |
Family
ID=62386492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019566199A Pending JP2020521797A (ja) | 2017-06-02 | 2018-06-01 | 抗がん剤組み合わせ治療 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11198726B2 (enExample) |
| EP (1) | EP3630822A1 (enExample) |
| JP (1) | JP2020521797A (enExample) |
| KR (1) | KR20200013231A (enExample) |
| CN (1) | CN110691790A (enExample) |
| AU (1) | AU2018277227A1 (enExample) |
| BR (1) | BR112019022074A2 (enExample) |
| CA (1) | CA3061053A1 (enExample) |
| CL (1) | CL2019003430A1 (enExample) |
| IL (1) | IL270905A (enExample) |
| MX (1) | MX2019014199A (enExample) |
| PH (1) | PH12019502692A1 (enExample) |
| WO (1) | WO2018220169A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017537896A (ja) | 2014-11-10 | 2017-12-21 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 二重特異性抗体及び眼科に使用する方法 |
| BR112017009790A2 (pt) * | 2014-11-10 | 2017-12-19 | Hoffmann La Roche | anticorpos direcionados ao anti-ang2 e métodos de uso |
| AU2015345320A1 (en) | 2014-11-10 | 2017-04-06 | F. Hoffmann-La Roche Ag | Anti-IL-1beta antibodies and methods of use |
| CA3061053A1 (en) * | 2017-06-02 | 2018-12-06 | Boehringer Ingelheim International Gmbh | Anti-cancer combination therapy |
| WO2021209458A1 (en) | 2020-04-14 | 2021-10-21 | Ares Trading S.A. | Combination treatment of cancer |
| EP4237423B1 (en) | 2020-11-02 | 2024-12-11 | Boehringer Ingelheim International GmbH | Substituted 1h-pyrazolo[4,3-c]pyridines and derivatives as egfr inhibitors |
| MX2023005192A (es) | 2020-11-04 | 2023-05-15 | Heidelberg Pharma Res Gmbh | Composicion que comprende una combinacion de inhibidor de punto de control inmunitario y conjugado de anticuerpo-amatoxina para uso en la terapia del cancer. |
| WO2022194988A2 (en) | 2021-03-19 | 2022-09-22 | Heidelberg Pharma Research Gmbh | B-lymphocyte specific amatoxin antibody conjugates |
| JP2024534964A (ja) * | 2021-09-10 | 2024-09-26 | ソーター・バイオファーマ・プライベイト・リミテッド | 抗ang2抗体、その調製方法及び使用 |
| KR20250099224A (ko) | 2022-11-01 | 2025-07-01 | 하이델베르크 파마 리서치 게엠베하 | 항-gucy2c 항체 및 이의 용도 |
| EP4680285A1 (en) | 2023-03-13 | 2026-01-21 | Heidelberg Pharma Research GmbH | Subcutaneously administered antibody-drug conjugates for use in cancer treatment |
| CN120025456B (zh) * | 2024-03-13 | 2025-11-07 | 寻济生物科技(北京)有限公司 | 一种抗vegfa融合构建体及其制备方法和应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU600575B2 (en) | 1987-03-18 | 1990-08-16 | Sb2, Inc. | Altered antibodies |
| EP1498427B1 (en) | 1992-08-21 | 2009-12-16 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| CA2433877C (en) | 2001-01-17 | 2014-11-18 | Aptevo Research And Development Llc | Binding domain-immunoglobulin fusion proteins |
| US20050284249A1 (en) | 2004-06-29 | 2005-12-29 | Arnone David F | Worm type gear mover assembly |
| AU2005293752A1 (en) | 2004-10-13 | 2006-04-20 | Ablynx N.V. | Single domain camelide anti-amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as Alzheimer's disease |
| ES2720160T3 (es) | 2005-05-09 | 2019-07-18 | Ono Pharmaceutical Co | Anticuerpos monoclonales humanos contra muerte programada 1(PD-1) y métodos para tratar el cáncer usando anticuerpos dirigidos contra PD-1 solos o junto con otras sustancias inmunoterapéuticas |
| RU2464276C2 (ru) | 2005-05-18 | 2012-10-20 | Аблинкс Н.В. | Улучшенные нанотела против фактора некроза опухоли-альфа |
| JP5191537B2 (ja) | 2007-06-18 | 2013-05-08 | エム・エス・ディー・オス・ベー・フェー | ヒトのプログラムされたデスレセプターpd−1に対する抗体 |
| EP2242773B1 (en) | 2008-02-11 | 2017-06-14 | Cure Tech Ltd. | Monoclonal antibodies for tumor treatment |
| CN101965362A (zh) | 2008-03-05 | 2011-02-02 | 埃博灵克斯股份有限公司 | 新型抗原结合二聚体-复合物及其制备方法和应用 |
| EP2262837A4 (en) | 2008-03-12 | 2011-04-06 | Merck Sharp & Dohme | PD-1 BINDING PROTEINS |
| US8268314B2 (en) | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
| US9527925B2 (en) * | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| HUE044263T2 (hu) * | 2012-03-30 | 2019-10-28 | Boehringer Ingelheim Int | ANG2-kötõ molekulák |
| JP2015532272A (ja) * | 2012-09-28 | 2015-11-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 二重アンジオポエチン−2/Dll4結合剤および抗VEGF−R剤を含む薬学的組み合わせ |
| WO2014049100A1 (en) * | 2012-09-28 | 2014-04-03 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations comprising dual angiopoietin-2 / dll4 binders and anti-vegf agents |
| ES2716685T3 (es) | 2014-01-24 | 2019-06-14 | Dana Farber Cancer Inst Inc | Moléculas de anticuerpo para PD-1 y usos de las mismas |
| CN107406502A (zh) * | 2015-04-23 | 2017-11-28 | 豪夫迈·罗氏有限公司 | 结合血管生成素2的抗体与结合编程性死亡配体1的抗体的组合疗法 |
| WO2016170039A1 (en) | 2015-04-23 | 2016-10-27 | F. Hoffmann-La Roche Ag | Combination therapy of antibody binding to angiopoietin 2 with antibody binding to programmed death 1 polypeptide |
| CN108025051B (zh) | 2015-07-29 | 2021-12-24 | 诺华股份有限公司 | 包含抗pd-1抗体分子的联合疗法 |
| WO2017165681A1 (en) * | 2016-03-24 | 2017-09-28 | Gensun Biopharma Inc. | Trispecific inhibitors for cancer treatment |
| EP3848393A1 (en) * | 2016-05-18 | 2021-07-14 | Boehringer Ingelheim International GmbH | Antibody molecules for cancer treatment |
| CA3061053A1 (en) * | 2017-06-02 | 2018-12-06 | Boehringer Ingelheim International Gmbh | Anti-cancer combination therapy |
| US10793634B2 (en) * | 2017-06-09 | 2020-10-06 | Boehringer Ingelheim International Gmbh | Anti-TrkB antibodies |
-
2018
- 2018-06-01 CA CA3061053A patent/CA3061053A1/en active Pending
- 2018-06-01 MX MX2019014199A patent/MX2019014199A/es unknown
- 2018-06-01 US US15/995,375 patent/US11198726B2/en active Active
- 2018-06-01 BR BR112019022074-7A patent/BR112019022074A2/pt not_active IP Right Cessation
- 2018-06-01 EP EP18727819.7A patent/EP3630822A1/en not_active Ceased
- 2018-06-01 AU AU2018277227A patent/AU2018277227A1/en not_active Abandoned
- 2018-06-01 WO PCT/EP2018/064445 patent/WO2018220169A1/en not_active Ceased
- 2018-06-01 CN CN201880036511.5A patent/CN110691790A/zh active Pending
- 2018-06-01 KR KR1020197035427A patent/KR20200013231A/ko not_active Withdrawn
- 2018-06-01 JP JP2019566199A patent/JP2020521797A/ja active Pending
-
2019
- 2019-11-25 CL CL2019003430A patent/CL2019003430A1/es unknown
- 2019-11-25 IL IL270905A patent/IL270905A/en unknown
- 2019-11-28 PH PH12019502692A patent/PH12019502692A1/en unknown
-
2021
- 2021-11-08 US US17/520,748 patent/US20220340651A1/en not_active Abandoned
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