JP2020521797A5 - - Google Patents

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Publication number
JP2020521797A5
JP2020521797A5 JP2019566199A JP2019566199A JP2020521797A5 JP 2020521797 A5 JP2020521797 A5 JP 2020521797A5 JP 2019566199 A JP2019566199 A JP 2019566199A JP 2019566199 A JP2019566199 A JP 2019566199A JP 2020521797 A5 JP2020521797 A5 JP 2020521797A5
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JP
Japan
Prior art keywords
compound
pharmaceutical composition
seq
treatment
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019566199A
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English (en)
Japanese (ja)
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JP2020521797A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2018/064445 external-priority patent/WO2018220169A1/en
Publication of JP2020521797A publication Critical patent/JP2020521797A/ja
Publication of JP2020521797A5 publication Critical patent/JP2020521797A5/ja
Pending legal-status Critical Current

Links

JP2019566199A 2017-06-02 2018-06-01 抗がん剤組み合わせ治療 Pending JP2020521797A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP17174323.0 2017-06-02
EP17174323 2017-06-02
EP17196949 2017-10-17
EP17196949.6 2017-10-17
PCT/EP2018/064445 WO2018220169A1 (en) 2017-06-02 2018-06-01 Anti-cancer combination therapy

Publications (2)

Publication Number Publication Date
JP2020521797A JP2020521797A (ja) 2020-07-27
JP2020521797A5 true JP2020521797A5 (enExample) 2021-07-26

Family

ID=62386492

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019566199A Pending JP2020521797A (ja) 2017-06-02 2018-06-01 抗がん剤組み合わせ治療

Country Status (13)

Country Link
US (2) US11198726B2 (enExample)
EP (1) EP3630822A1 (enExample)
JP (1) JP2020521797A (enExample)
KR (1) KR20200013231A (enExample)
CN (1) CN110691790A (enExample)
AU (1) AU2018277227A1 (enExample)
BR (1) BR112019022074A2 (enExample)
CA (1) CA3061053A1 (enExample)
CL (1) CL2019003430A1 (enExample)
IL (1) IL270905A (enExample)
MX (1) MX2019014199A (enExample)
PH (1) PH12019502692A1 (enExample)
WO (1) WO2018220169A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017537896A (ja) 2014-11-10 2017-12-21 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 二重特異性抗体及び眼科に使用する方法
BR112017009790A2 (pt) * 2014-11-10 2017-12-19 Hoffmann La Roche anticorpos direcionados ao anti-ang2 e métodos de uso
AU2015345320A1 (en) 2014-11-10 2017-04-06 F. Hoffmann-La Roche Ag Anti-IL-1beta antibodies and methods of use
CA3061053A1 (en) * 2017-06-02 2018-12-06 Boehringer Ingelheim International Gmbh Anti-cancer combination therapy
WO2021209458A1 (en) 2020-04-14 2021-10-21 Ares Trading S.A. Combination treatment of cancer
EP4237423B1 (en) 2020-11-02 2024-12-11 Boehringer Ingelheim International GmbH Substituted 1h-pyrazolo[4,3-c]pyridines and derivatives as egfr inhibitors
MX2023005192A (es) 2020-11-04 2023-05-15 Heidelberg Pharma Res Gmbh Composicion que comprende una combinacion de inhibidor de punto de control inmunitario y conjugado de anticuerpo-amatoxina para uso en la terapia del cancer.
WO2022194988A2 (en) 2021-03-19 2022-09-22 Heidelberg Pharma Research Gmbh B-lymphocyte specific amatoxin antibody conjugates
JP2024534964A (ja) * 2021-09-10 2024-09-26 ソーター・バイオファーマ・プライベイト・リミテッド 抗ang2抗体、その調製方法及び使用
KR20250099224A (ko) 2022-11-01 2025-07-01 하이델베르크 파마 리서치 게엠베하 항-gucy2c 항체 및 이의 용도
EP4680285A1 (en) 2023-03-13 2026-01-21 Heidelberg Pharma Research GmbH Subcutaneously administered antibody-drug conjugates for use in cancer treatment
CN120025456B (zh) * 2024-03-13 2025-11-07 寻济生物科技(北京)有限公司 一种抗vegfa融合构建体及其制备方法和应用

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AU600575B2 (en) 1987-03-18 1990-08-16 Sb2, Inc. Altered antibodies
EP1498427B1 (en) 1992-08-21 2009-12-16 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
CA2433877C (en) 2001-01-17 2014-11-18 Aptevo Research And Development Llc Binding domain-immunoglobulin fusion proteins
US20050284249A1 (en) 2004-06-29 2005-12-29 Arnone David F Worm type gear mover assembly
AU2005293752A1 (en) 2004-10-13 2006-04-20 Ablynx N.V. Single domain camelide anti-amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as Alzheimer's disease
ES2720160T3 (es) 2005-05-09 2019-07-18 Ono Pharmaceutical Co Anticuerpos monoclonales humanos contra muerte programada 1(PD-1) y métodos para tratar el cáncer usando anticuerpos dirigidos contra PD-1 solos o junto con otras sustancias inmunoterapéuticas
RU2464276C2 (ru) 2005-05-18 2012-10-20 Аблинкс Н.В. Улучшенные нанотела против фактора некроза опухоли-альфа
JP5191537B2 (ja) 2007-06-18 2013-05-08 エム・エス・ディー・オス・ベー・フェー ヒトのプログラムされたデスレセプターpd−1に対する抗体
EP2242773B1 (en) 2008-02-11 2017-06-14 Cure Tech Ltd. Monoclonal antibodies for tumor treatment
CN101965362A (zh) 2008-03-05 2011-02-02 埃博灵克斯股份有限公司 新型抗原结合二聚体-复合物及其制备方法和应用
EP2262837A4 (en) 2008-03-12 2011-04-06 Merck Sharp & Dohme PD-1 BINDING PROTEINS
US8268314B2 (en) 2008-10-08 2012-09-18 Hoffmann-La Roche Inc. Bispecific anti-VEGF/anti-ANG-2 antibodies
US9527925B2 (en) * 2011-04-01 2016-12-27 Boehringer Ingelheim International Gmbh Bispecific binding molecules binding to VEGF and ANG2
HUE044263T2 (hu) * 2012-03-30 2019-10-28 Boehringer Ingelheim Int ANG2-kötõ molekulák
JP2015532272A (ja) * 2012-09-28 2015-11-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 二重アンジオポエチン−2/Dll4結合剤および抗VEGF−R剤を含む薬学的組み合わせ
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CN107406502A (zh) * 2015-04-23 2017-11-28 豪夫迈·罗氏有限公司 结合血管生成素2的抗体与结合编程性死亡配体1的抗体的组合疗法
WO2016170039A1 (en) 2015-04-23 2016-10-27 F. Hoffmann-La Roche Ag Combination therapy of antibody binding to angiopoietin 2 with antibody binding to programmed death 1 polypeptide
CN108025051B (zh) 2015-07-29 2021-12-24 诺华股份有限公司 包含抗pd-1抗体分子的联合疗法
WO2017165681A1 (en) * 2016-03-24 2017-09-28 Gensun Biopharma Inc. Trispecific inhibitors for cancer treatment
EP3848393A1 (en) * 2016-05-18 2021-07-14 Boehringer Ingelheim International GmbH Antibody molecules for cancer treatment
CA3061053A1 (en) * 2017-06-02 2018-12-06 Boehringer Ingelheim International Gmbh Anti-cancer combination therapy
US10793634B2 (en) * 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies

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