CA3061053A1 - Anti-cancer combination therapy - Google Patents
Anti-cancer combination therapy Download PDFInfo
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- CA3061053A1 CA3061053A1 CA3061053A CA3061053A CA3061053A1 CA 3061053 A1 CA3061053 A1 CA 3061053A1 CA 3061053 A CA3061053 A CA 3061053A CA 3061053 A CA3061053 A CA 3061053A CA 3061053 A1 CA3061053 A1 CA 3061053A1
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- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| CA2963175A1 (en) | 2014-11-10 | 2016-05-19 | F. Hoffmann-La Roche Ag | Bispecific antibodies and methods of use in ophthalmology |
| CN110691790A (zh) * | 2017-06-02 | 2020-01-14 | 勃林格殷格翰国际有限公司 | 抗癌联合治疗 |
| WO2021209458A1 (en) | 2020-04-14 | 2021-10-21 | Ares Trading S.A. | Combination treatment of cancer |
| EP4237423B1 (en) | 2020-11-02 | 2024-12-11 | Boehringer Ingelheim International GmbH | Substituted 1h-pyrazolo[4,3-c]pyridines and derivatives as egfr inhibitors |
| KR20230104653A (ko) | 2020-11-04 | 2023-07-10 | 하이델베르크 파마 리서치 게엠베하 | 암 요법에 사용하기 위한 면역 체크포인트 억제제 및 항체-아마톡신 접합체의 조합물을 포함하는 조성물 |
| KR20230159480A (ko) | 2021-03-19 | 2023-11-21 | 하이델베르크 파마 리서치 게엠베하 | B-림프구 특이적 아마톡신 항체 접합체 |
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| WO2025189977A1 (zh) * | 2024-03-13 | 2025-09-18 | 寻济生物科技（北京）有限公司 | 一种抗vegfa融合构建体及其制备方法和应用 |
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| DE3883899T3 (de) | 1987-03-18 | 1999-04-22 | Sb2, Inc., Danville, Calif. | Geänderte antikörper. |
| ES2325541T3 (es) | 1992-08-21 | 2009-09-08 | Vrije Universiteit Brussel | Inmunoglobulinas desprovistas de cadenas ligeras. |
| JP2004525620A (ja) | 2001-01-17 | 2004-08-26 | トルビオン・ファーマシューティカルズ・インコーポレイテッド | 結合ドメイン−免疫グロブリン融合タンパク質 |
| US20050284249A1 (en) | 2004-06-29 | 2005-12-29 | Arnone David F | Worm type gear mover assembly |
| BRPI0518151A2 (pt) | 2004-10-13 | 2009-06-16 | Ablynx Nv | polipetìdeos contra amiloide-beta, ácido nucléico que codifica tal polipetìdeo, composição compreendendo tal polipetìdeo, método para produzir um polipetìdeo e uso do mesmo |
| CN103059138B (zh) | 2005-05-09 | 2015-10-28 | 小野药品工业株式会社 | 程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法 |
| JP5047950B2 (ja) | 2005-05-18 | 2012-10-10 | アブリンクス エン．ヴェー． | 腫瘍壊死因子−アルファに対する改良ナノボディ（商標） |
| KR101586617B1 (ko) | 2007-06-18 | 2016-01-20 | 머크 샤프 앤 도메 비.브이. | 사람 프로그램된 사멸 수용체 ｐｄ-1에 대한 항체 |
| BRPI0907718A2 (pt) | 2008-02-11 | 2017-06-13 | Curetech Ltd | método para tratar um tumor, método para melhorar a tolerabilidade a pelo menos um agente quimiterápico, método para aumentar a sobrevida de um indivíduo que tem um tumor, método para reduzir ou prevenir recidiva tumoral, uso de um anticorpo monoclonal humanizado ou seu fragmento e anticorpo monoclonal humanizado ou seu fragmento |
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| EP2831111B1 (en) * | 2012-03-30 | 2019-03-20 | Boehringer Ingelheim International GmbH | Ang2-binding molecules |
| EP2900260A1 (en) * | 2012-09-28 | 2015-08-05 | Boehringer Ingelheim International GmbH | Pharmaceutical combinations comprising dual angiopoietin-2 / dll4 binders and anti-vegf agents |
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| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
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| US10894823B2 (en) * | 2016-03-24 | 2021-01-19 | Gensun Biopharma Inc. | Trispecific inhibitors for cancer treatment |
| WO2017198741A1 (en) * | 2016-05-18 | 2017-11-23 | Boehringer Ingelheim International Gmbh | Anti pd-1 and anti-lag3 antibodies for cancer treatment |
| CN110691790A (zh) * | 2017-06-02 | 2020-01-14 | 勃林格殷格翰国际有限公司 | 抗癌联合治疗 |
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| IL270905A (en) | 2020-01-30 |
| EP3630822A1 (en) | 2020-04-08 |
| AU2018277227A1 (en) | 2019-10-31 |
| KR20200013231A (ko) | 2020-02-06 |
| WO2018220169A1 (en) | 2018-12-06 |
| US20220340651A1 (en) | 2022-10-27 |
| BR112019022074A2 (pt) | 2020-05-12 |
| CN110691790A (zh) | 2020-01-14 |
| MX2019014199A (es) | 2020-01-23 |
| CL2019003430A1 (es) | 2020-05-08 |
| JP2020521797A (ja) | 2020-07-27 |
| PH12019502692A1 (en) | 2020-07-13 |
| US20180346559A1 (en) | 2018-12-06 |
| US11198726B2 (en) | 2021-12-14 |
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