JP2020516646A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020516646A5 JP2020516646A5 JP2019555852A JP2019555852A JP2020516646A5 JP 2020516646 A5 JP2020516646 A5 JP 2020516646A5 JP 2019555852 A JP2019555852 A JP 2019555852A JP 2019555852 A JP2019555852 A JP 2019555852A JP 2020516646 A5 JP2020516646 A5 JP 2020516646A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- patient
- niraparib
- composition according
- acetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 58
- PCHKPVIQAHNQLW-CQSZACIVSA-N niraparib Chemical compound N1=C2C(C(=O)N)=CC=CC2=CN1C(C=C1)=CC=C1[C@@H]1CCCNC1 PCHKPVIQAHNQLW-CQSZACIVSA-N 0.000 claims description 42
- 229950011068 niraparib Drugs 0.000 claims description 42
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 40
- 239000008194 pharmaceutical composition Substances 0.000 claims description 35
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 claims description 35
- 229960004618 prednisone Drugs 0.000 claims description 35
- 239000000203 mixture Substances 0.000 claims description 26
- 206010060862 Prostate cancer Diseases 0.000 claims description 12
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims description 12
- 239000006186 oral dosage form Substances 0.000 claims description 4
- 229940123237 Taxane Drugs 0.000 claims description 2
- 102000001307 androgen receptors Human genes 0.000 claims description 2
- 108010080146 androgen receptors Proteins 0.000 claims description 2
- 238000002512 chemotherapy Methods 0.000 claims description 2
- 229940088597 hormone Drugs 0.000 claims description 2
- 239000005556 hormone Substances 0.000 claims description 2
- 230000008685 targeting Effects 0.000 claims description 2
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims description 2
- 238000002560 therapeutic procedure Methods 0.000 claims description 2
- 229960004103 abiraterone acetate Drugs 0.000 claims 1
- UVIQSJCZCSLXRZ-UBUQANBQSA-N abiraterone acetate Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CC[C@@H](CC4=CC[C@H]31)OC(=O)C)C=C2C1=CC=CN=C1 UVIQSJCZCSLXRZ-UBUQANBQSA-N 0.000 claims 1
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022117192A JP7407880B2 (ja) | 2017-04-13 | 2022-07-22 | 前立腺癌の併用療法 |
| JP2023196574A JP2024023344A (ja) | 2017-04-13 | 2023-11-20 | 前立腺癌の併用療法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762485164P | 2017-04-13 | 2017-04-13 | |
| US62/485,164 | 2017-04-13 | ||
| PCT/US2018/026661 WO2018191141A1 (en) | 2017-04-13 | 2018-04-09 | Combination therapy for prostate cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022117192A Division JP7407880B2 (ja) | 2017-04-13 | 2022-07-22 | 前立腺癌の併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020516646A JP2020516646A (ja) | 2020-06-11 |
| JP2020516646A5 true JP2020516646A5 (enExample) | 2021-07-26 |
| JP7141408B2 JP7141408B2 (ja) | 2022-09-22 |
Family
ID=62067858
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019555852A Active JP7141408B2 (ja) | 2017-04-13 | 2018-04-09 | 前立腺癌の併用療法 |
| JP2022117192A Active JP7407880B2 (ja) | 2017-04-13 | 2022-07-22 | 前立腺癌の併用療法 |
| JP2023196574A Pending JP2024023344A (ja) | 2017-04-13 | 2023-11-20 | 前立腺癌の併用療法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022117192A Active JP7407880B2 (ja) | 2017-04-13 | 2022-07-22 | 前立腺癌の併用療法 |
| JP2023196574A Pending JP2024023344A (ja) | 2017-04-13 | 2023-11-20 | 前立腺癌の併用療法 |
Country Status (33)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL322013A (en) | 2016-07-29 | 2025-09-01 | Janssen Pharmaceutica Nv | Niraparib or its salts for use in the treatment of prostate cancer |
| WO2020139339A1 (en) * | 2018-12-27 | 2020-07-02 | Constellation Pharmaceuticals, Inc. | Ezh2 and androgen receptor signaling inhibitors as tools for targeting prostate cancer |
| JP7442328B2 (ja) * | 2020-02-03 | 2024-03-04 | 株式会社三共 | 遊技機 |
| CN113546037B (zh) * | 2020-04-20 | 2024-12-27 | 鲁南制药集团股份有限公司 | 一种醋酸阿比特龙栓剂及其制备方法 |
| UA130040C2 (uk) * | 2020-05-08 | 2025-10-22 | Янссен Фармацевтика Нв | Види лікування раку передміхурової залози за допомогою комбінацій абіратерону ацетату та нірапарибу |
| CN114306236B (zh) * | 2021-12-15 | 2022-10-21 | 湖南慧泽生物医药科技有限公司 | 用于负载醋酸阿比特龙的自微乳体系及组合物和应用 |
| TWI828471B (zh) | 2021-12-15 | 2024-01-01 | 大陸商湖南慧澤生物醫藥科技有限公司 | 醋酸阿比特龍的自微乳組合物和應用 |
| CA3254950A1 (en) * | 2022-04-07 | 2023-10-12 | Astrazeneca Ab | Polytherapy for the treatment of cancer |
| WO2024203348A1 (ja) * | 2023-03-31 | 2024-10-03 | ソニーグループ株式会社 | 腫瘍の解析方法、腫瘍の解析システム、及び腫瘍の解析データ生成方法 |
| WO2025027138A1 (en) * | 2023-08-02 | 2025-02-06 | Janssen Pharmaceutica Nv | Combination of niraparib and abiraterone for use in the treatment of metastatic castration-resistant prostate cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080051380A1 (en) * | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
| JP2010501575A (ja) * | 2006-08-25 | 2010-01-21 | クオウガル バイオテクノロジー，インコーポレイテッド | 癌を治療するための方法及び組成物 |
| EP3536690A1 (en) | 2007-01-10 | 2019-09-11 | MSD Italia S.r.l. | Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors |
| JP5989965B2 (ja) | 2008-01-08 | 2016-09-07 | メルク シャープ エンド ドーム リミテッド | ２−｛４−［（３ｓ）−ピペリジン−３−イル］フェニル｝−２ｈ−インダゾール−７−カルボキサミドの薬学的に許容される塩 |
| WO2012009475A1 (en) * | 2010-07-14 | 2012-01-19 | Oregon Health & Science University | Methods of treating cancer with inhibition of lysine-specific demethylase 1 |
| US9314473B2 (en) * | 2011-02-03 | 2016-04-19 | Pop Test Oncology Limited Liability Company | System and method for diagnosis and treatment |
| WO2014089324A1 (en) * | 2012-12-07 | 2014-06-12 | Calitor Sciences, Llc | Substituted cyclic compounds and methods of use |
-
2017
- 2017-06-16 JO JOP/2019/0244A patent/JOP20190244A1/ar unknown
-
2018
- 2018-04-09 EP EP22200801.3A patent/EP4176878A1/en active Pending
- 2018-04-09 MY MYPI2023006196A patent/MY209010A/en unknown
- 2018-04-09 PL PL18720895.4T patent/PL3609497T3/pl unknown
- 2018-04-09 PE PE2019002030A patent/PE20200444A1/es unknown
- 2018-04-09 RS RS20221127A patent/RS63832B1/sr unknown
- 2018-04-09 EA EA201992430A patent/EA201992430A1/ru unknown
- 2018-04-09 EP EP18720895.4A patent/EP3609497B1/en active Active
- 2018-04-09 LT LTEPPCT/US2018/026661T patent/LT3609497T/lt unknown
- 2018-04-09 MD MDE20200190T patent/MD3609497T2/ro not_active IP Right Cessation
- 2018-04-09 JP JP2019555852A patent/JP7141408B2/ja active Active
- 2018-04-09 EP EP22200882.3A patent/EP4176879A1/en not_active Withdrawn
- 2018-04-09 MX MX2019012296A patent/MX2019012296A/es unknown
- 2018-04-09 WO PCT/US2018/026661 patent/WO2018191141A1/en not_active Ceased
- 2018-04-09 UA UAA201911057A patent/UA129514C2/uk unknown
- 2018-04-09 HR HRP20221327TT patent/HRP20221327T1/hr unknown
- 2018-04-09 CA CA3059562A patent/CA3059562A1/en active Pending
- 2018-04-09 KR KR1020197032257A patent/KR20190134718A/ko not_active Ceased
- 2018-04-09 CN CN202411589875.XA patent/CN119235874A/zh active Pending
- 2018-04-09 CN CN201880039365.1A patent/CN110753545A/zh active Pending
- 2018-04-09 AU AU2018251594A patent/AU2018251594A1/en not_active Abandoned
- 2018-04-09 ES ES18720895T patent/ES2931052T3/es active Active
- 2018-04-09 SG SG11201909552V patent/SG11201909552VA/en unknown
- 2018-04-09 PT PT187208954T patent/PT3609497T/pt unknown
- 2018-04-09 HU HUE18720895A patent/HUE060460T2/hu unknown
- 2018-04-09 SM SM20220467T patent/SMT202200467T1/it unknown
- 2018-04-09 MA MA48728A patent/MA48728B1/fr unknown
- 2018-04-09 CR CR20190467A patent/CR20190467A/es unknown
- 2018-04-09 IL IL320452A patent/IL320452A/en unknown
- 2018-04-09 DK DK18720895.4T patent/DK3609497T3/da active
- 2018-04-09 IL IL269879A patent/IL269879B2/en unknown
- 2018-04-11 US US15/950,707 patent/US20180296574A1/en active Pending
-
2019
- 2019-10-08 CL CL2019002871A patent/CL2019002871A1/es unknown
- 2019-10-09 NI NI201900105A patent/NI201900105A/es unknown
- 2019-10-10 PH PH12019502317A patent/PH12019502317A1/en unknown
- 2019-10-14 MX MX2023009569A patent/MX2023009569A/es unknown
- 2019-10-14 DO DO2019000264A patent/DOP2019000264A/es unknown
- 2019-10-18 CO CONC2019/0011591A patent/CO2019011591A2/es unknown
-
2022
- 2022-02-25 US US17/680,553 patent/US20220175801A1/en not_active Abandoned
- 2022-07-22 JP JP2022117192A patent/JP7407880B2/ja active Active
-
2023
- 2023-11-20 JP JP2023196574A patent/JP2024023344A/ja active Pending
-
2024
- 2024-02-01 US US18/429,778 patent/US20240245710A1/en active Pending
- 2024-04-11 AU AU2024202346A patent/AU2024202346A1/en active Pending
- 2024-08-09 US US18/799,339 patent/US20240398837A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020516646A5 (enExample) | ||
| IL320452A (en) | Combination therapy for prostate cancer | |
| JP2023041862A5 (enExample) | ||
| JP2024015120A5 (enExample) | ||
| JP2016540738A5 (enExample) | ||
| JP2019536805A5 (enExample) | ||
| JP2015519329A5 (enExample) | ||
| JP2012522837A5 (enExample) | ||
| JP2019516733A5 (enExample) | ||
| JP2017516802A5 (enExample) | ||
| Zheng et al. | Randomized, double-blind, placebo-controlled trial of shuanghua baihe tablets to prevent oral mucositis in patients with nasopharyngeal cancer undergoing chemoradiation therapy | |
| JP2018503610A5 (enExample) | ||
| TWI441639B (zh) | 用於治療卵巢癌之包含紫杉醇之組合 | |
| TW200501945A (en) | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases | |
| HRP20192189T1 (hr) | Doziranja i terapijske primjene l-4-klorokinurenina | |
| JP2016505050A5 (enExample) | ||
| JP2019507786A5 (enExample) | ||
| RU2005126819A (ru) | Усовершенствованное лечение опухолей | |
| JP2017537927A5 (enExample) | ||
| JP2010504307A5 (enExample) | ||
| MX2024006270A (es) | Nueva composicion farmaceutica oral y regimen de dosificacion para la terapia de enfermedades pulmonares intersticiales fibrosantes progresivas. | |
| JP2019535830A5 (enExample) | ||
| JP2018522881A5 (enExample) | ||
| RU2020108631A (ru) | Новая вспомогательная терапия для применения в способе лечения рака простаты | |
| JP2020536903A5 (enExample) |