JP2018522881A5 - - Google Patents
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- Publication number
- JP2018522881A5 JP2018522881A5 JP2017568264A JP2017568264A JP2018522881A5 JP 2018522881 A5 JP2018522881 A5 JP 2018522881A5 JP 2017568264 A JP2017568264 A JP 2017568264A JP 2017568264 A JP2017568264 A JP 2017568264A JP 2018522881 A5 JP2018522881 A5 JP 2018522881A5
- Authority
- JP
- Japan
- Prior art keywords
- dose
- administered
- antibody
- pharmaceutical composition
- multiple myeloma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562185968P | 2015-06-29 | 2015-06-29 | |
| US62/185,968 | 2015-06-29 | ||
| US201562239965P | 2015-10-11 | 2015-10-11 | |
| US62/239,965 | 2015-10-11 | ||
| US201562262574P | 2015-12-03 | 2015-12-03 | |
| US62/262,574 | 2015-12-03 | ||
| PCT/US2016/039723 WO2017003990A1 (en) | 2015-06-29 | 2016-06-28 | Immunotherapeutic dosing regimens comprising pomalidomide and an anti-cs1 antibody for treating cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018522881A JP2018522881A (ja) | 2018-08-16 |
| JP2018522881A5 true JP2018522881A5 (enExample) | 2019-07-25 |
| JP6754785B2 JP6754785B2 (ja) | 2020-09-16 |
Family
ID=56409706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568264A Active JP6754785B2 (ja) | 2015-06-29 | 2016-06-28 | 免疫治療投与レジメンおよびその組合せ |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10925867B2 (enExample) |
| EP (2) | EP3950065A1 (enExample) |
| JP (1) | JP6754785B2 (enExample) |
| CN (1) | CN107949425A (enExample) |
| BR (1) | BR112017027692A2 (enExample) |
| CA (1) | CA2990478A1 (enExample) |
| CY (1) | CY1124543T1 (enExample) |
| DK (1) | DK3313528T3 (enExample) |
| EA (1) | EA035888B1 (enExample) |
| ES (1) | ES2886657T3 (enExample) |
| HR (1) | HRP20211478T1 (enExample) |
| HU (1) | HUE056491T2 (enExample) |
| LT (1) | LT3313528T (enExample) |
| MX (1) | MX391581B (enExample) |
| PL (1) | PL3313528T3 (enExample) |
| PT (1) | PT3313528T (enExample) |
| RS (1) | RS62352B1 (enExample) |
| SI (1) | SI3313528T1 (enExample) |
| SM (1) | SMT202100567T1 (enExample) |
| WO (1) | WO2017003990A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202300081T1 (it) * | 2014-08-22 | 2023-05-12 | Celgene Corp | Metodi di trattamento di mieloma multiplo con composti immunomodulatori in combinazione con anticorpi |
| PL3313528T3 (pl) * | 2015-06-29 | 2021-12-13 | Bristol-Myers Squibb Company | Schematy dawkowania immunoterapeutycznego obejmujące pomalidomid i przeciwciało anty-cs1 w leczeniu raka |
| EP3488851A1 (en) * | 2018-10-03 | 2019-05-29 | AVM Biotechnology, LLC | Immunoablative therapies |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA204125A (en) | 1920-09-21 | Sylvester Pratt Edwin | Gramophone operated toy | |
| US819826A (en) | 1905-12-14 | 1906-05-08 | Frank R Welcher | Stanchion. |
| US5851795A (en) | 1991-06-27 | 1998-12-22 | Bristol-Myers Squibb Company | Soluble CTLA4 molecules and uses thereof |
| US5855887A (en) | 1995-07-25 | 1999-01-05 | The Regents Of The University Of California | Blockade of lymphocyte down-regulation associated with CTLA-4 signaling |
| US5811097A (en) | 1995-07-25 | 1998-09-22 | The Regents Of The University Of California | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US6051227A (en) | 1995-07-25 | 2000-04-18 | The Regents Of The University Of California, Office Of Technology Transfer | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US6281230B1 (en) | 1996-07-24 | 2001-08-28 | Celgene Corporation | Isoindolines, method of use, and pharmaceutical compositions |
| US5635517B1 (en) | 1996-07-24 | 1999-06-29 | Celgene Corp | Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines |
| JP2001523958A (ja) | 1997-03-21 | 2001-11-27 | ブライハム アンド ウィミンズ ホスピタル,インコーポレイテッド | 免疫療法のctla−4結合ペプチド |
| DK2112166T3 (en) | 1998-12-23 | 2019-02-04 | Pfizer | Human monoclonal antibodies to CTLA-4 |
| US7109003B2 (en) | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
| EE05627B1 (et) | 1998-12-23 | 2013-02-15 | Pfizer Inc. | CTLA-4 vastased inimese monoklonaalsed antikehad |
| SK287200B6 (sk) | 1999-02-22 | 2010-03-08 | Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf) | C-21 modifikované epotilóny, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a použitie |
| US7629360B2 (en) | 1999-05-07 | 2009-12-08 | Celgene Corporation | Methods for the treatment of cachexia and graft v. host disease |
| US7605238B2 (en) | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| NZ517202A (en) | 1999-08-24 | 2004-05-28 | Medarex Inc | Human CTLA-4 antibodies and their uses |
| EP1261376A1 (en) | 2000-01-27 | 2002-12-04 | Genetics Institute, LLC | Antibodies against ctla4(cd152), conjugates comprising same, and uses thereof |
| US7041499B2 (en) | 2001-12-12 | 2006-05-09 | University Of North Texas Health Science Center | Immuno activation of CS1 receptor in natural killer cells to inhibit tumor cell growth |
| US7968569B2 (en) | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| CN1981761B (zh) * | 2002-05-17 | 2011-10-12 | 细胞基因公司 | 使用免疫调节性化合物用于制备治疗和控制癌症和其它疾病药物中的应用及组合物 |
| PL216630B1 (pl) | 2002-10-17 | 2014-04-30 | Genmab As | Izolowane ludzkie przeciwciało monoklonalne wiążące ludzki CD20, związane z tym przeciwciałem transfektoma, komórka gospodarza, transgeniczne zwierzę lub roślina, kompozycja, immunokoniugat, cząsteczka bispecyficzna, wektor ekspresyjny, kompozycja farmaceutyczna, zastosowanie medyczne, zestaw oraz przeciwciało antyidiotypowe i jego zastosowanie |
| US20050025763A1 (en) | 2003-05-08 | 2005-02-03 | Protein Design Laboratories, Inc. | Therapeutic use of anti-CS1 antibodies |
| US7709610B2 (en) | 2003-05-08 | 2010-05-04 | Facet Biotech Corporation | Therapeutic use of anti-CS1 antibodies |
| US6958115B2 (en) | 2003-06-24 | 2005-10-25 | The United States Of America As Represented By The Secretary Of The Navy | Low temperature refining and formation of refractory metals |
| ES2720160T3 (es) | 2005-05-09 | 2019-07-18 | Ono Pharmaceutical Co | Anticuerpos monoclonales humanos contra muerte programada 1(PD-1) y métodos para tratar el cáncer usando anticuerpos dirigidos contra PD-1 solos o junto con otras sustancias inmunoterapéuticas |
| PT2068874E (pt) * | 2006-08-07 | 2015-05-21 | Abbvie Biotherapeutics Inc | Métodos de tratamento de mieloma múltiplo utilizando terapias de combinação baseadas em anticorpos anti-csi |
| EP2069478A2 (en) | 2006-08-07 | 2009-06-17 | PDL BioPharma, Inc. | Use of allogeneic effector cells and anti-cs1 antibodies for selective killing of multiple myeloma cells |
| CN101534860B (zh) * | 2006-08-07 | 2013-03-27 | 艾伯特生物治疗学公司 | 使用抗cs1-抗体治疗多发性骨髓瘤的组合物和方法 |
| JP2010500370A (ja) * | 2006-08-07 | 2010-01-07 | ピーディーエル バイオファーマ,インコーポレイティド | 多発性硬化症を処置するための抗cs1抗体を用いる組成物および方法 |
| KR20110096536A (ko) | 2008-10-31 | 2011-08-30 | 애보트 바이오테라퓨틱스 코포레이션 | 희귀 림프종의 치료를 위한 항cs1 항체의 용도 |
| EP3199149A1 (en) | 2009-05-19 | 2017-08-02 | Celgene Corporation | Formulations of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione |
| WO2011053321A1 (en) | 2009-10-30 | 2011-05-05 | University Of Arkansas For Medical Science | Use of autologous effector cells for treatment of multiple myeloma |
| WO2011053322A1 (en) | 2009-10-30 | 2011-05-05 | University Of Arkansas For Medical Science | Use of autologous effector cells and antibodies for treatment of multiple myeloma |
| US9506481B1 (en) | 2013-01-31 | 2016-11-29 | Daniel Theobald | High force hydraulic actuator |
| HK1232121A1 (zh) * | 2014-01-13 | 2018-01-05 | University Of Central Florida Research Foundation, Inc. | 作为抗氧化治疗的富勒烯化合物 |
| SMT202300081T1 (it) | 2014-08-22 | 2023-05-12 | Celgene Corp | Metodi di trattamento di mieloma multiplo con composti immunomodulatori in combinazione con anticorpi |
| JP2017537893A (ja) * | 2014-10-31 | 2017-12-21 | アッヴィ・バイオセラピューティクス・インコーポレイテッド | 抗cs1抗体および抗体薬結合体 |
| PL3313528T3 (pl) * | 2015-06-29 | 2021-12-13 | Bristol-Myers Squibb Company | Schematy dawkowania immunoterapeutycznego obejmujące pomalidomid i przeciwciało anty-cs1 w leczeniu raka |
-
2016
- 2016-06-28 PL PL16738609T patent/PL3313528T3/pl unknown
- 2016-06-28 SM SM20210567T patent/SMT202100567T1/it unknown
- 2016-06-28 LT LTEPPCT/US2016/039723T patent/LT3313528T/lt unknown
- 2016-06-28 HR HRP20211478TT patent/HRP20211478T1/hr unknown
- 2016-06-28 SI SI201631351T patent/SI3313528T1/sl unknown
- 2016-06-28 BR BR112017027692A patent/BR112017027692A2/pt not_active Application Discontinuation
- 2016-06-28 PT PT167386093T patent/PT3313528T/pt unknown
- 2016-06-28 EA EA201890035A patent/EA035888B1/ru not_active IP Right Cessation
- 2016-06-28 CN CN201680049473.8A patent/CN107949425A/zh active Pending
- 2016-06-28 HU HUE16738609A patent/HUE056491T2/hu unknown
- 2016-06-28 EP EP21187060.5A patent/EP3950065A1/en not_active Withdrawn
- 2016-06-28 EP EP16738609.3A patent/EP3313528B1/en active Active
- 2016-06-28 JP JP2017568264A patent/JP6754785B2/ja active Active
- 2016-06-28 MX MX2017015765A patent/MX391581B/es unknown
- 2016-06-28 DK DK16738609.3T patent/DK3313528T3/da active
- 2016-06-28 US US15/738,412 patent/US10925867B2/en active Active
- 2016-06-28 RS RS20211157A patent/RS62352B1/sr unknown
- 2016-06-28 ES ES16738609T patent/ES2886657T3/es active Active
- 2016-06-28 CA CA2990478A patent/CA2990478A1/en active Pending
- 2016-06-28 WO PCT/US2016/039723 patent/WO2017003990A1/en not_active Ceased
-
2021
- 2021-01-15 US US17/150,099 patent/US20210154183A1/en not_active Abandoned
- 2021-09-28 CY CY20211100854T patent/CY1124543T1/el unknown
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