JP2014500278A5 - - Google Patents
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- JP2014500278A5 JP2014500278A5 JP2013543410A JP2013543410A JP2014500278A5 JP 2014500278 A5 JP2014500278 A5 JP 2014500278A5 JP 2013543410 A JP2013543410 A JP 2013543410A JP 2013543410 A JP2013543410 A JP 2013543410A JP 2014500278 A5 JP2014500278 A5 JP 2014500278A5
- Authority
- JP
- Japan
- Prior art keywords
- dose
- composition
- days
- initial dose
- interval
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42199210P | 2010-12-10 | 2010-12-10 | |
| US61/421,992 | 2010-12-10 | ||
| PCT/US2011/064496 WO2012079093A2 (en) | 2010-12-10 | 2011-12-12 | Dosage and administration of bispecific scfv conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014500278A JP2014500278A (ja) | 2014-01-09 |
| JP2014500278A5 true JP2014500278A5 (enExample) | 2015-01-29 |
Family
ID=46207797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013543410A Withdrawn JP2014500278A (ja) | 2010-12-10 | 2011-12-12 | 二重特異性ｓｃＦｖコンジュゲートの投薬量および投与 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140017264A1 (enExample) |
| EP (1) | EP2648753A4 (enExample) |
| JP (1) | JP2014500278A (enExample) |
| AU (1) | AU2011341337A1 (enExample) |
| CA (1) | CA2819554A1 (enExample) |
| WO (1) | WO2012079093A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG178789A1 (en) | 2007-02-16 | 2012-03-29 | Merrimack Pharmaceuticals Inc | Antibodies against erbb3 and uses thereof |
| KR101798679B1 (ko) | 2010-03-11 | 2017-11-16 | 메리맥 파마슈티컬즈, 인크. | ３중 음성 및 기저형 유방암 치료 시의 ｅｒｂｂ３ 저해제의 용도 |
| EA201291181A1 (ru) | 2010-05-06 | 2013-05-30 | Новартис Аг | Композиции и способы применения терапевтических поливалентных антител против белка, родственного рецептору липопротеинов низкой плотности 6 (lrp6) |
| CA2798432A1 (en) | 2010-05-06 | 2011-11-10 | Novartis Ag | Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies |
| CN103547598A (zh) * | 2011-02-24 | 2014-01-29 | 梅里麦克制药股份有限公司 | 包含抗-erbb3药剂的联合治疗 |
| KR20140091031A (ko) | 2011-11-04 | 2014-07-18 | 노파르티스 아게 | 저밀도 지단백질-관련 단백질 6 (lrp6) - 반감기 연장제 구축물 |
| EP2847226A4 (en) * | 2012-05-11 | 2016-05-11 | Merrimack Pharmaceuticals Inc | DOSAGE AND ADMINISTRATION OF BIS SPECIFIC SCFV CONJUGATES IN COMBINATION WITH ANTICROBIAL AGENTS |
| WO2014036520A1 (en) | 2012-08-30 | 2014-03-06 | Merrimack Pharmaceuticals, Inc. | Combination therapies comprising anti-erbb3 agents |
| EP3087394A2 (en) | 2013-12-27 | 2016-11-02 | Merrimack Pharmaceuticals, Inc. | Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies |
| WO2016022723A1 (en) | 2014-08-05 | 2016-02-11 | Merrimack Pharmaceuticals, Inc. | Combination therapies for treating her2-positive cancers that are resistant to her2-targeted therapies |
| US10184006B2 (en) | 2015-06-04 | 2019-01-22 | Merrimack Pharmaceuticals, Inc. | Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors |
| CN106729743B (zh) | 2015-11-23 | 2021-09-21 | 四川科伦博泰生物医药股份有限公司 | 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090226429A1 (en) * | 2001-05-25 | 2009-09-10 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
| BRPI0911652A2 (pt) * | 2008-04-11 | 2015-08-04 | Merrimack Pharmaceuticals Inc | Ligantes de albumina sérica humana e seus conjugados |
-
2011
- 2011-12-12 JP JP2013543410A patent/JP2014500278A/ja not_active Withdrawn
- 2011-12-12 EP EP11847515.1A patent/EP2648753A4/en not_active Withdrawn
- 2011-12-12 AU AU2011341337A patent/AU2011341337A1/en not_active Abandoned
- 2011-12-12 US US13/992,460 patent/US20140017264A1/en not_active Abandoned
- 2011-12-12 CA CA2819554A patent/CA2819554A1/en not_active Abandoned
- 2011-12-12 WO PCT/US2011/064496 patent/WO2012079093A2/en not_active Ceased
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