MX2011007854A - Metodos para tratar infartos agudos al miocardio y trastornos relacionados. - Google Patents

Metodos para tratar infartos agudos al miocardio y trastornos relacionados.

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Publication number
MX2011007854A
MX2011007854A MX2011007854A MX2011007854A MX2011007854A MX 2011007854 A MX2011007854 A MX 2011007854A MX 2011007854 A MX2011007854 A MX 2011007854A MX 2011007854 A MX2011007854 A MX 2011007854A MX 2011007854 A MX2011007854 A MX 2011007854A
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MX
Mexico
Prior art keywords
acute myocardial
methods
associated disorders
treating acute
myocardial infarctions
Prior art date
Application number
MX2011007854A
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English (en)
Inventor
Karl Kossen
Jeff Olgin
Original Assignee
Univ California
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Application filed by Univ California filed Critical Univ California
Publication of MX2011007854A publication Critical patent/MX2011007854A/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

La invención se refiere a métodos para tratar a pacientes que han sufrido un infarto agudo al miocardio (IMA) con un compuesto terapéutico que tiene efectos antifibróticos, por ejemplo, la pirfenidona y sus análogos. El método para tratar al paciente que ha sufrido un infarto agudo al miocardio puede incluir administrarle al paciente una dosis terapéuticamente efectiva de un compuesto terapéutico que tiene un efecto antifibrótico, en donde el tratamiento opcionalmente se inicia entre 1 y 42 días después de ocurrido el IAM y opcionalmente se prolonga durante hasta 3 y 6 meses.
MX2011007854A 2009-01-26 2010-01-26 Metodos para tratar infartos agudos al miocardio y trastornos relacionados. MX2011007854A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14734009P 2009-01-26 2009-01-26
PCT/US2010/022112 WO2010085805A1 (en) 2009-01-26 2010-01-26 Methods for treating acute myocardial infarctions and associated disorders

Publications (1)

Publication Number Publication Date
MX2011007854A true MX2011007854A (es) 2011-08-15

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ID=42354646

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011007854A MX2011007854A (es) 2009-01-26 2010-01-26 Metodos para tratar infartos agudos al miocardio y trastornos relacionados.

Country Status (16)

Country Link
US (2) US20100190731A1 (es)
EP (1) EP2389227A4 (es)
JP (1) JP2012515800A (es)
KR (1) KR20110114684A (es)
CN (1) CN102292124A (es)
AP (1) AP2011005824A0 (es)
AU (1) AU2010206543A1 (es)
BR (1) BRPI1006979A2 (es)
CA (1) CA2747251A1 (es)
CL (1) CL2011001811A1 (es)
IL (1) IL213526A0 (es)
MX (1) MX2011007854A (es)
NI (1) NI201100147A (es)
SG (1) SG172981A1 (es)
TN (1) TN2011000364A1 (es)
WO (1) WO2010085805A1 (es)

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CA2747251A1 (en) 2010-07-29
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US20100190731A1 (en) 2010-07-29
US20110218515A1 (en) 2011-09-08
SG172981A1 (en) 2011-08-29
AP2011005824A0 (en) 2011-08-31
EP2389227A4 (en) 2012-08-08
AU2010206543A1 (en) 2011-07-07
EP2389227A1 (en) 2011-11-30
IL213526A0 (en) 2011-07-31
CN102292124A (zh) 2011-12-21
CL2011001811A1 (es) 2011-11-11
KR20110114684A (ko) 2011-10-19
JP2012515800A (ja) 2012-07-12
TN2011000364A1 (en) 2013-03-27
WO2010085805A1 (en) 2010-07-29

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