CL2011001811A1 - Un metodo para tratar un paciente que ha sufrido un infarto agudo al miocardio que comprende el uso de un agente antifibrotico. - Google Patents
Un metodo para tratar un paciente que ha sufrido un infarto agudo al miocardio que comprende el uso de un agente antifibrotico.Info
- Publication number
- CL2011001811A1 CL2011001811A1 CL2011001811A CL2011001811A CL2011001811A1 CL 2011001811 A1 CL2011001811 A1 CL 2011001811A1 CL 2011001811 A CL2011001811 A CL 2011001811A CL 2011001811 A CL2011001811 A CL 2011001811A CL 2011001811 A1 CL2011001811 A1 CL 2011001811A1
- Authority
- CL
- Chile
- Prior art keywords
- suffered
- patient
- treating
- myocardial infarction
- acute myocardial
- Prior art date
Links
- 206010000891 acute myocardial infarction Diseases 0.000 title abstract 2
- 230000003510 anti-fibrotic effect Effects 0.000 title abstract 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un método para tratar un paciente que ha sufrido un infarto agudo al miocardio que comprende el uso de un agente antifibrótico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14734009P | 2009-01-26 | 2009-01-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2011001811A1 true CL2011001811A1 (es) | 2011-11-11 |
Family
ID=42354646
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2011001811A CL2011001811A1 (es) | 2009-01-26 | 2011-07-26 | Un metodo para tratar un paciente que ha sufrido un infarto agudo al miocardio que comprende el uso de un agente antifibrotico. |
Country Status (16)
Country | Link |
---|---|
US (2) | US20100190731A1 (es) |
EP (1) | EP2389227A4 (es) |
JP (1) | JP2012515800A (es) |
KR (1) | KR20110114684A (es) |
CN (1) | CN102292124A (es) |
AP (1) | AP2011005824A0 (es) |
AU (1) | AU2010206543A1 (es) |
BR (1) | BRPI1006979A2 (es) |
CA (1) | CA2747251A1 (es) |
CL (1) | CL2011001811A1 (es) |
IL (1) | IL213526A0 (es) |
MX (1) | MX2011007854A (es) |
NI (1) | NI201100147A (es) |
SG (1) | SG172981A1 (es) |
TN (1) | TN2011000364A1 (es) |
WO (1) | WO2010085805A1 (es) |
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JP5722883B2 (ja) | 2009-05-25 | 2015-05-27 | 中南大学Central South University | 1−(置換ベンジル)−5−トリフルオロメチル−2−(1h)ピリドン化合物及びその塩、並びにその製造方法及びその用途 |
US8426407B2 (en) | 2009-05-25 | 2013-04-23 | Central South University | Preparation of 1-(substituted aryl)-5-trifluoromethyl-2-(1H)pyridone compounds and salts thereof and their applications |
NZ608813A (en) * | 2010-09-01 | 2014-11-28 | Genzyme Corp | Treatment of myocardial infarction using tgf - beta antagonists |
US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
US10092552B2 (en) | 2011-01-31 | 2018-10-09 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
WO2012122165A2 (en) | 2011-03-08 | 2012-09-13 | Auspex Pharmaceuticals, Inc. | Substituted n-aryl pyridinones |
FI20115234A0 (fi) | 2011-03-08 | 2011-03-08 | Biotie Therapies Corp | Uusia pyridatsinoni- ja pyridoniyhdisteitä |
MX2013013752A (es) * | 2011-05-25 | 2014-08-01 | Intermune Inc | Pirfenidona y tratamiento anti-fibrotico en pacientes seleccionados. |
CN103987858A (zh) | 2011-11-22 | 2014-08-13 | 英特芒尼公司 | 诊断和治疗特发性肺纤维化的方法 |
US9078918B2 (en) * | 2012-05-08 | 2015-07-14 | Northwestern University | Inhibition of fibrosis and AF by TGF-beta inhibition in the posterior left atrium (PLA) |
WO2013169914A1 (en) * | 2012-05-08 | 2013-11-14 | Northwestern University | Using intracardiac electrograms to predict location of fibrosis and autonomic nerves in the heart |
MX2015000830A (es) | 2012-07-18 | 2015-10-26 | Sunshine Lake Pharma Co Ltd | Derivados heterociclicos nitrogenosos y su aplicacion en farmacos. |
AR092742A1 (es) * | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
EP2968292A4 (en) | 2013-03-15 | 2016-11-23 | Intermune Inc | METHODS FOR IMPROVING MICROVASCULAR INTEGRITY |
ES2663806T3 (es) | 2013-12-19 | 2018-04-17 | unshine Lake Pharma Co., Ltd. | Derivados heterocíclicos nitrogenados y su aplicación en el tratamiento de la fibrosis tisular |
WO2015106150A1 (en) | 2014-01-10 | 2015-07-16 | Genoa Pharmaceuticals Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
KR102373700B1 (ko) | 2014-04-02 | 2022-03-11 | 인터뮨, 인크. | 항섬유성 피리디논 |
CN107922485A (zh) | 2015-06-15 | 2018-04-17 | 斯坦福大学托管董事会 | 诊断和治疗情绪障碍的方法 |
CN105085383B (zh) * | 2015-08-19 | 2017-09-01 | 四川大学 | 5‑甲基‑2(1h)吡啶酮衍生物及其制备方法和用途 |
CN105669562A (zh) * | 2016-04-05 | 2016-06-15 | 叶芳 | 一种氟取代嘧啶类化合物及其制备方法 |
RU2738844C2 (ru) * | 2016-04-14 | 2020-12-17 | Гуанчжоу Джойо Фарматек Ко., Лтд | Содержащее заместитель, представляющий собой бутан, в гетероциклическом кольце производное пиридона для лечения фиброза и воспалительных заболеваний |
CN107556234A (zh) * | 2016-06-30 | 2018-01-09 | 陕西合成药业股份有限公司 | 一种新型吡啶酮类化合物及其制备方法和在医学上的应用 |
EP3569249A4 (en) * | 2016-12-27 | 2020-11-11 | Osaka University | MEDICAL COMPOSITION FOR TREATMENT OF CONTINUOUS HEART DISEASE |
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CN107641098A (zh) * | 2017-09-06 | 2018-01-30 | 南阳师范学院 | 一种实现吡啶酮c6位烯基化的方法 |
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-
2010
- 2010-01-26 CN CN2010800055907A patent/CN102292124A/zh active Pending
- 2010-01-26 BR BRPI1006979A patent/BRPI1006979A2/pt not_active Application Discontinuation
- 2010-01-26 EP EP10734007A patent/EP2389227A4/en not_active Withdrawn
- 2010-01-26 US US12/693,906 patent/US20100190731A1/en not_active Abandoned
- 2010-01-26 AU AU2010206543A patent/AU2010206543A1/en not_active Abandoned
- 2010-01-26 CA CA2747251A patent/CA2747251A1/en not_active Abandoned
- 2010-01-26 MX MX2011007854A patent/MX2011007854A/es not_active Application Discontinuation
- 2010-01-26 AP AP2011005824A patent/AP2011005824A0/xx unknown
- 2010-01-26 KR KR1020117019794A patent/KR20110114684A/ko not_active Application Discontinuation
- 2010-01-26 WO PCT/US2010/022112 patent/WO2010085805A1/en active Application Filing
- 2010-01-26 SG SG2011050952A patent/SG172981A1/en unknown
- 2010-01-26 JP JP2011548228A patent/JP2012515800A/ja not_active Withdrawn
-
2011
- 2011-05-25 US US13/115,697 patent/US20110218515A1/en not_active Abandoned
- 2011-06-13 IL IL213526A patent/IL213526A0/en unknown
- 2011-07-22 TN TN2011000364A patent/TN2011000364A1/fr unknown
- 2011-07-25 NI NI201100147A patent/NI201100147A/es unknown
- 2011-07-26 CL CL2011001811A patent/CL2011001811A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
IL213526A0 (en) | 2011-07-31 |
BRPI1006979A2 (pt) | 2016-04-12 |
CN102292124A (zh) | 2011-12-21 |
AU2010206543A1 (en) | 2011-07-07 |
KR20110114684A (ko) | 2011-10-19 |
EP2389227A4 (en) | 2012-08-08 |
EP2389227A1 (en) | 2011-11-30 |
SG172981A1 (en) | 2011-08-29 |
AP2011005824A0 (en) | 2011-08-31 |
US20110218515A1 (en) | 2011-09-08 |
MX2011007854A (es) | 2011-08-15 |
WO2010085805A1 (en) | 2010-07-29 |
NI201100147A (es) | 2011-11-09 |
TN2011000364A1 (en) | 2013-03-27 |
JP2012515800A (ja) | 2012-07-12 |
US20100190731A1 (en) | 2010-07-29 |
CA2747251A1 (en) | 2010-07-29 |
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