JP2017535261A5 - - Google Patents
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- JP2017535261A5 JP2017535261A5 JP2017523279A JP2017523279A JP2017535261A5 JP 2017535261 A5 JP2017535261 A5 JP 2017535261A5 JP 2017523279 A JP2017523279 A JP 2017523279A JP 2017523279 A JP2017523279 A JP 2017523279A JP 2017535261 A5 JP2017535261 A5 JP 2017535261A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020208069A JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462073651P | 2014-10-31 | 2014-10-31 | |
| US62/073,651 | 2014-10-31 | ||
| PCT/US2015/055799 WO2016069283A1 (en) | 2014-10-31 | 2015-10-15 | Altering gene expression in cart cells and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020208069A Division JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017535261A JP2017535261A (ja) | 2017-11-30 |
| JP2017535261A5 true JP2017535261A5 (enExample) | 2018-11-15 |
| JP6879910B2 JP6879910B2 (ja) | 2021-06-02 |
Family
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Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523279A Active JP6879910B2 (ja) | 2014-10-31 | 2015-10-15 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2017523296A Ceased JP2018500006A (ja) | 2014-10-31 | 2015-10-15 | 改変ｔ細胞における遺伝子発現の改変およびその使用 |
| JP2020208069A Active JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2023004286A Active JP7657474B2 (ja) | 2014-10-31 | 2023-01-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2025043131A Pending JP2025089344A (ja) | 2014-10-31 | 2025-03-18 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523296A Ceased JP2018500006A (ja) | 2014-10-31 | 2015-10-15 | 改変ｔ細胞における遺伝子発現の改変およびその使用 |
| JP2020208069A Active JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2023004286A Active JP7657474B2 (ja) | 2014-10-31 | 2023-01-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2025043131A Pending JP2025089344A (ja) | 2014-10-31 | 2025-03-18 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (7) | US11208661B2 (enExample) |
| EP (4) | EP3215166B9 (enExample) |
| JP (5) | JP6879910B2 (enExample) |
| KR (5) | KR102781429B1 (enExample) |
| CN (3) | CN114836385B (enExample) |
| AU (4) | AU2015339743C1 (enExample) |
| BR (1) | BR112017008693A2 (enExample) |
| CA (2) | CA2964948A1 (enExample) |
| EA (1) | EA201790953A1 (enExample) |
| ES (1) | ES2983094T3 (enExample) |
| MX (2) | MX2017005698A (enExample) |
| PL (1) | PL3215166T3 (enExample) |
| WO (2) | WO2016069282A1 (enExample) |
Families Citing this family (205)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10323236B2 (en) | 2011-07-22 | 2019-06-18 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| SG11201400513PA (en) | 2011-09-08 | 2014-06-27 | Yeda Res & Dev | Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
| US9340800B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | Extended DNA-sensing GRNAS |
| US20150166984A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting alpha-antitrypsin point mutations |
| CN111471675A (zh) | 2014-03-05 | 2020-07-31 | 国立大学法人神户大学 | 特异性转变靶向dna序列的核酸碱基的基因组序列的修饰方法、及其使用的分子复合体 |
| US11390921B2 (en) | 2014-04-01 | 2022-07-19 | Adaptive Biotechnologies Corporation | Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs) |
| EP4219687B1 (en) | 2014-04-23 | 2024-08-14 | Juno Therapeutics, Inc. | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
| CA2964948A1 (en) | 2014-10-31 | 2016-05-06 | The Trustees Of The University Of Pennsylvania | Altering gene expression in modified t cells and uses thereof |
| KR102763527B1 (ko) | 2014-12-03 | 2025-02-05 | 애질런트 테크놀로지스, 인크. | 화학적 변형을 갖는 가이드 rna |
| SG11201706236SA (en) | 2015-02-06 | 2017-08-30 | Nat Univ Singapore | Methods for enhancing efficacy of therapeutic immune cells |
| EP3273976B1 (en) * | 2015-03-27 | 2023-07-26 | President and Fellows of Harvard College | Modified t cells and methods of making and using the same |
| JP6873911B2 (ja) | 2015-04-06 | 2021-05-19 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 初代細胞において標的核酸の遺伝子調節を誘導するためにインビトロで行う方法 |
| HK1254190A1 (zh) | 2015-05-08 | 2019-07-12 | President And Fellows Of Harvard College | 通用供体干细胞和相关方法 |
| CA2991690A1 (en) | 2015-07-16 | 2017-01-19 | Yeda Research And Development Co. Ltd. | Genetically modified anti-third party central memory t cells and use of same in immunotherapy |
| GB2595063B (en) | 2015-07-31 | 2022-03-09 | Univ Minnesota | Modified cells and methods of therapy |
| ES2883116T3 (es) | 2015-10-05 | 2021-12-07 | Prec Biosciences Inc | Meganucleasas diseñadas con secuencias de reconocimiento encontradas en el gen de la región constante alfa del receptor de células T humanas |
| IL287319B2 (en) | 2015-10-05 | 2023-02-01 | Prec Biosciences Inc | Genetically-modified cells comprising a modified human t cell receptor alpha constant region gene |
| US12043852B2 (en) | 2015-10-23 | 2024-07-23 | President And Fellows Of Harvard College | Evolved Cas9 proteins for gene editing |
| WO2017090761A1 (ja) | 2015-11-27 | 2017-06-01 | 国立大学法人神戸大学 | 標的化したｄｎａ配列の核酸塩基を特異的に変換する、単子葉植物のゲノム配列の変換方法、及びそれに用いる分子複合体 |
| MA43380A (fr) | 2015-12-03 | 2018-10-10 | Juno Therapeutics Inc | Récepteurs chimériques modifiés et compositions et procédés associés |
| CN121294437A (zh) * | 2015-12-04 | 2026-01-09 | 诺华股份有限公司 | 用于免疫肿瘤学的组合物和方法 |
| EP4299136A3 (en) | 2015-12-16 | 2024-02-14 | Gritstone bio, Inc. | Neoantigen identification, manufacture, and use |
| WO2017192536A1 (en) | 2016-05-02 | 2017-11-09 | University Of Kansas | Eliminating mhc restriction from the t cell receptor as a strategy for immunotherapy |
| US10767175B2 (en) | 2016-06-08 | 2020-09-08 | Agilent Technologies, Inc. | High specificity genome editing using chemically modified guide RNAs |
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| US20170274014A1 (en) | 2014-07-21 | 2017-09-28 | Jennifer Brogdon | Combinations of low, immune enhancing, doses of mtor inhibitors and cars |
| US10201597B2 (en) | 2014-09-30 | 2019-02-12 | The Regents Of The University Of California | Codon-optimized lentiviral vector for stem cell reprogramming |
| WO2016057850A1 (en) * | 2014-10-09 | 2016-04-14 | Seattle Children' S Hospital (Dba Seattle Children' S Research Institute) | Long poly (a) plasmids and methods for introduction of long poly (a) sequences into the plasmid |
| CA2964948A1 (en) | 2014-10-31 | 2016-05-06 | The Trustees Of The University Of Pennsylvania | Altering gene expression in modified t cells and uses thereof |
| CA2978186A1 (en) | 2015-03-05 | 2016-09-09 | Fred Hutchinson Cancer Research Center | Immunomodulatory fusion proteins and uses thereof |
| EP3273976B1 (en) * | 2015-03-27 | 2023-07-26 | President and Fellows of Harvard College | Modified t cells and methods of making and using the same |
| US10934336B2 (en) * | 2017-04-13 | 2021-03-02 | The Trustees Of The University Of Pennsylvania | Use of gene editing to generate universal TCR re-directed T cells for adoptive immunotherapy |
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