|
WO2013066438A2
(en)
|
2011-07-22 |
2013-05-10 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
|
US9526784B2
(en)
|
2013-09-06 |
2016-12-27 |
President And Fellows Of Harvard College |
Delivery system for functional nucleases
|
|
US9340799B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
MRNA-sensing switchable gRNAs
|
|
US20150166984A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting alpha-antitrypsin point mutations
|
|
AU2015298571B2
(en)
|
2014-07-30 |
2020-09-03 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
US10201606B2
(en)
|
2014-11-26 |
2019-02-12 |
Miltenyi Biotec Gmbh |
Combination immunotherapy of antigen-recognizing receptors and hematopoietic cells for the treatment of diseases
|
|
IL258491B2
(en)
|
2015-10-16 |
2023-09-01 |
Univ Columbia |
Preparations and methods for inhibiting antigens of a particular lineage
|
|
WO2017070632A2
(en)
|
2015-10-23 |
2017-04-27 |
President And Fellows Of Harvard College |
Nucleobase editors and uses thereof
|
|
EP3370741B1
(en)
*
|
2015-11-04 |
2025-10-08 |
The Trustees of the University of Pennsylvania |
Methods and compositions for gene editing in hematopoietic stem cells
|
|
WO2017143266A1
(en)
*
|
2016-02-19 |
2017-08-24 |
The Regents Of The University Of California |
Short hairpin rna (shrna734) and use of same to positively select and eliminate genetically modified cells
|
|
WO2018027078A1
(en)
|
2016-08-03 |
2018-02-08 |
President And Fellows Of Harard College |
Adenosine nucleobase editors and uses thereof
|
|
AU2017308889B2
(en)
|
2016-08-09 |
2023-11-09 |
President And Fellows Of Harvard College |
Programmable Cas9-recombinase fusion proteins and uses thereof
|
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
KR20240007715A
(ko)
|
2016-10-14 |
2024-01-16 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵염기 에디터의 aav 전달
|
|
US20190365806A1
(en)
*
|
2016-11-02 |
2019-12-05 |
Universität Basel |
Immunologically discernible cell surface variants for use in cell therapy
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
KR102709603B1
(ko)
*
|
2017-02-28 |
2024-09-27 |
보르 바이오파마 인크. |
계통 특이적 단백질의 억제를 위한 조성물 및 방법
|
|
WO2018165504A1
(en)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
|
KR20190123328A
(ko)
|
2017-03-09 |
2019-10-31 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
암 백신
|
|
CN110914310A
(zh)
|
2017-03-10 |
2020-03-24 |
哈佛大学的校长及成员们 |
胞嘧啶至鸟嘌呤碱基编辑器
|
|
IL306092A
(en)
|
2017-03-23 |
2023-11-01 |
Harvard College |
Nucleic base editors that include nucleic acid programmable DNA binding proteins
|
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
|
EP3658573A1
(en)
|
2017-07-28 |
2020-06-03 |
President and Fellows of Harvard College |
Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace)
|
|
EP3676376B1
(en)
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
High efficiency base editors comprising gam
|
|
CA3082251A1
(en)
|
2017-10-16 |
2019-04-25 |
The Broad Institute, Inc. |
Uses of adenosine base editors
|
|
US12406749B2
(en)
|
2017-12-15 |
2025-09-02 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
CN112654710A
(zh)
|
2018-05-16 |
2021-04-13 |
辛瑟高公司 |
用于指导rna设计和使用的方法和系统
|
|
WO2019226953A1
(en)
|
2018-05-23 |
2019-11-28 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
IL260445B
(en)
*
|
2018-07-05 |
2019-08-29 |
Lempo Therapeutics Ltd |
Methods and compositions for modulating myeloperoxidase (mpo) expression
|
|
EP3820495A4
(en)
|
2018-07-09 |
2022-07-20 |
The Broad Institute Inc. |
RNA-PROGRAMMABLE EPIGENETIC RNA MODIFIERS AND THEIR USES
|
|
CA3110837A1
(en)
|
2018-08-28 |
2020-03-05 |
Vor Biopharma Inc. |
Genetically engineered hematopoietic stem cells and uses thereof
|
|
AU2019345052B2
(en)
|
2018-09-19 |
2025-09-04 |
FUJIFILM Cellular Dynamics, Inc. |
Protein L for activation and expansion of chimeric antigen receptor-modified immune cells
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
US12624086B2
(en)
*
|
2018-10-31 |
2026-05-12 |
Mayo Foundation For Medical Education And Research |
Materials and methods for treating cancer
|
|
CN109852627B
(zh)
*
|
2018-12-26 |
2022-07-05 |
中国人民解放军军事科学院军事医学研究院 |
用于CRISPRi系统的质粒、其构建方法及其在使鼠疫菌目的基因定向沉默中的应用
|
|
EP3911371A4
(en)
*
|
2019-01-18 |
2023-04-26 |
University of Southern California |
METHODS AND COMPOSITIONS FOR IMPROVING THE SAFETY AND EFFICACY OF CELL THERAPY
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
WO2020172638A1
(en)
*
|
2019-02-22 |
2020-08-27 |
The Trustees Of The University Of Pennsylvania |
Crispr/cas9 knock-out of cd33 in human hematopoietic stem/ progenitor cells for allogenic transplantation
|
|
EP4219700A1
(en)
|
2019-03-07 |
2023-08-02 |
The Regents of the University of California |
Crispr-cas effector polypeptides and methods of use thereof
|
|
WO2020191241A1
(en)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
WO2020214842A1
(en)
|
2019-04-17 |
2020-10-22 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
WO2021041977A1
(en)
*
|
2019-08-28 |
2021-03-04 |
Vor Biopharma, Inc. |
Compositions and methods for cd123 modification
|
|
AU2020338011A1
(en)
*
|
2019-08-28 |
2022-03-10 |
Vor Biopharma Inc. |
Compositions and methods for CLL1 modification
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
AU2020361683A1
(en)
|
2019-10-11 |
2022-05-19 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for targeting CD13 and TIM-3 with CAR T cells to treat acute myeloid leukemia
|
|
KR102923195B1
(ko)
|
2020-02-28 |
2026-02-04 |
현대자동차주식회사 |
리튬이온 전지 음극 제조방법 및 이에 의해 제조된 리튬이온 전지 음극을 포함하는 리튬이온 전지
|
|
CA3177481A1
(en)
|
2020-05-08 |
2021-11-11 |
David R. Liu |
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
|
|
EP3909612A1
(en)
*
|
2020-05-12 |
2021-11-17 |
Life Science Inkubator Betriebs GmbH & Co. KG |
Composition of nanoparticles
|
|
AU2021413252A1
(en)
*
|
2020-12-31 |
2023-06-08 |
Vor Biopharma Inc. |
Compositions and methods for cd34 gene modification
|
|
CN115443333B
(zh)
*
|
2021-04-27 |
2025-04-25 |
上海驯鹿生物技术有限公司 |
一种基因编辑的造血干细胞及其与car-t细胞的联合应用
|
|
PE20252304A1
(es)
*
|
2021-04-28 |
2025-09-22 |
Eisai Randd Man Co Ltd |
Oligonucleotidos antisentido y su uso para el tratamiento de trastornos neurodegenerativos
|
|
EP4430186A1
(en)
*
|
2021-11-09 |
2024-09-18 |
Vor Biopharma Inc. |
Compositions and methods for erm2 modification
|
|
EP4433512A4
(en)
|
2021-11-19 |
2025-12-31 |
Univ Pennsylvania |
Genetically modified pan-leukocyte-specific CD45 antigen to facilitate T-lymphocyte therapy
|
|
EP4463190A4
(en)
*
|
2022-01-11 |
2026-01-14 |
Actinium Pharmaceuticals Inc |
TREATMENT METHODS FOR CD33-POSITIVE HEMATOLOGICAL MALIGNITIES
|
|
WO2025030010A1
(en)
|
2023-08-01 |
2025-02-06 |
Vor Biopharma Inc. |
Compositions comprising genetically engineered hematopoietic stem cells and methods of use thereof
|
|
WO2025059062A1
(en)
*
|
2023-09-11 |
2025-03-20 |
The Trustees Of The University Of Pennsylvania |
Genetic engineering of human hematopoietic stem/progenitor cells (hspcs) for locus-specific expression of therapeutic proteins
|