JP2015145426A5 - - Google Patents

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Publication number
JP2015145426A5
JP2015145426A5 JP2015099613A JP2015099613A JP2015145426A5 JP 2015145426 A5 JP2015145426 A5 JP 2015145426A5 JP 2015099613 A JP2015099613 A JP 2015099613A JP 2015099613 A JP2015099613 A JP 2015099613A JP 2015145426 A5 JP2015145426 A5 JP 2015145426A5
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degrees
crystal
peak
composition
further characterized
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JP2015099613A
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JP2015145426A (ja
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JP2015099613A 2007-12-07 2015-05-15 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態 Pending JP2015145426A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1216207P 2007-12-07 2007-12-07
US61/012,162 2007-12-07

Related Parent Applications (1)

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JP2014028062A Division JP2014088447A (ja) 2007-12-07 2014-02-18 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態

Related Child Applications (1)

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JP2016207622A Division JP6227741B2 (ja) 2007-12-07 2016-10-24 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態

Publications (2)

Publication Number Publication Date
JP2015145426A JP2015145426A (ja) 2015-08-13
JP2015145426A5 true JP2015145426A5 (OSRAM) 2016-05-19

Family

ID=40344271

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2010537037A Withdrawn JP2011506330A (ja) 2007-12-07 2008-12-04 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2013194966A Pending JP2013253111A (ja) 2007-12-07 2013-09-20 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2014028062A Pending JP2014088447A (ja) 2007-12-07 2014-02-18 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2015099613A Pending JP2015145426A (ja) 2007-12-07 2015-05-15 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2016207622A Active JP6227741B2 (ja) 2007-12-07 2016-10-24 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2017112429A Pending JP2017149778A (ja) 2007-12-07 2017-06-07 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2010537037A Withdrawn JP2011506330A (ja) 2007-12-07 2008-12-04 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2013194966A Pending JP2013253111A (ja) 2007-12-07 2013-09-20 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2014028062A Pending JP2014088447A (ja) 2007-12-07 2014-02-18 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016207622A Active JP6227741B2 (ja) 2007-12-07 2016-10-24 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態
JP2017112429A Pending JP2017149778A (ja) 2007-12-07 2017-06-07 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソル−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の固体状形態

Country Status (28)

Country Link
US (8) US8507534B2 (OSRAM)
EP (3) EP2225230B1 (OSRAM)
JP (6) JP2011506330A (OSRAM)
KR (3) KR20100101130A (OSRAM)
CN (2) CN103626744B (OSRAM)
AU (1) AU2008333845C1 (OSRAM)
BR (1) BRPI0821039B8 (OSRAM)
CA (2) CA2706920C (OSRAM)
CL (1) CL2010000607A1 (OSRAM)
CY (3) CY1118630T1 (OSRAM)
DK (2) DK3170818T3 (OSRAM)
EA (1) EA201070698A1 (OSRAM)
ES (3) ES2611077T3 (OSRAM)
HR (2) HRP20170241T2 (OSRAM)
HU (3) HUE049642T2 (OSRAM)
IL (2) IL206203A (OSRAM)
LT (3) LT3170818T (OSRAM)
MX (2) MX2010006179A (OSRAM)
NO (2) NO2017009I2 (OSRAM)
NZ (4) NZ614151A (OSRAM)
PL (2) PL3170818T3 (OSRAM)
PT (2) PT2225230T (OSRAM)
RS (2) RS55559B1 (OSRAM)
SG (1) SG186638A1 (OSRAM)
SI (2) SI2225230T1 (OSRAM)
UA (1) UA102534C2 (OSRAM)
WO (1) WO2009073757A1 (OSRAM)
ZA (1) ZA201003623B (OSRAM)

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* Cited by examiner, † Cited by third party
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UA104601C2 (uk) * 2008-10-23 2014-02-25 Вертекс Фармасьютікалз, Інкорпорейтед Модулятори регулятора трансмембранної провідності при муковісцидозі
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RS54783B1 (sr) * 2010-04-07 2016-10-31 Vertex Pharma Čvrste forme 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksiamido)-3-metilpiridin-2-il)benzoeve kiseline
DK3150198T3 (da) 2010-04-07 2021-11-01 Vertex Pharma Farmaceutiske sammensætninger af 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioxol-5-yl)-cyclopropancarboxamido)-3-methylpyriodin-2-yl)benzoesyre og indgivelse deraf
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AU2018279646B2 (en) 2017-06-08 2023-04-06 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
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TWI799435B (zh) 2017-08-02 2023-04-21 美商維泰克斯製藥公司 製備化合物之製程
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WO2019079760A1 (en) 2017-10-19 2019-04-25 Vertex Pharmaceuticals Incorporated CRYSTALLINE FORMS AND COMPOSITIONS OF CFTR MODULATORS
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US20190210973A1 (en) 2018-01-05 2019-07-11 The Curators Of The University Of Missouri Compounds and methods for treatment of cystic fibrosis
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LT3752510T (lt) 2018-02-15 2023-04-11 Vertex Pharmaceuticals Incorporated Makrocikliniai junginiai kaip cistinės fibrozės transmembraninio laidumo reguliatoriaus moduliatoriai, jų farmacinės kompozicijos, jų panaudojimas cistinės fibrozės gydymui ir jų gamybos būdas
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UY38630A (es) 2019-04-03 2020-10-30 Vertex Pharma Agentes moduladores del regulador de la conductancia transmembrana de la fibrosis quística
WO2020214921A1 (en) 2019-04-17 2020-10-22 Vertex Pharmaceuticals Incorporated Solid forms of modulators of cftr
MX2022001827A (es) 2019-08-14 2022-06-09 Vertex Pharma Moduladores del regulador de conductancia transmembrana de la fibrosis quistica.
US11584761B2 (en) 2019-08-14 2023-02-21 Vertex Pharmaceuticals Incorporated Process of making CFTR modulators
TWI867024B (zh) 2019-08-14 2024-12-21 美商維泰克斯製藥公司 囊腫纖維化跨膜傳導調節蛋白之調節劑
EP4013760A1 (en) 2019-08-14 2022-06-22 Vertex Pharmaceuticals Incorporated Crystalline forms of cftr modulators
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CR20230120A (es) 2020-08-07 2023-09-01 Vertex Pharma Moduladores del regulador de la conductancia transmembrana de la fibrosis quística
KR20230052954A (ko) 2020-08-20 2023-04-20 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 점액 과다분비를 특징으로 하는 호흡기 질환의 치료 방법
WO2022076626A1 (en) 2020-10-07 2022-04-14 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
US20230373935A1 (en) 2020-10-07 2023-11-23 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
EP4225762A1 (en) 2020-10-07 2023-08-16 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
EP4225765A2 (en) 2020-10-07 2023-08-16 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
US20230382924A1 (en) 2020-10-07 2023-11-30 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
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