|
FR2224175B1
(enExample)
|
1973-04-04 |
1978-04-14 |
Isf Spa |
|
|
IT1017153B
(it)
*
|
1974-07-15 |
1977-07-20 |
Isf Spa |
Apparecchio per inalazioni
|
|
US4010148A
(en)
*
|
1975-05-12 |
1977-03-01 |
Board Of Regents Of The University Of Texas System |
Purified thymosin and process
|
|
US4148788A
(en)
*
|
1978-01-23 |
1979-04-10 |
Hoffmann-La Roche Inc. |
Synthesis of thymosin α1
|
|
US4247066A
(en)
*
|
1978-02-21 |
1981-01-27 |
General Dynamics Corporation |
Airfoil variable cambering device and method
|
|
US4321260A
(en)
|
1980-05-22 |
1982-03-23 |
Ayerst, Mckenna & Harrison Inc. |
Method of using gonadorelin for the treatment of benign prostatic hyperplasia
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
SE438261B
(sv)
*
|
1981-07-08 |
1985-04-15 |
Draco Ab |
Anvendning i dosinhalator av ett perforerat membran
|
|
US4652548A
(en)
*
|
1981-08-27 |
1987-03-24 |
Eli Lilly And Company |
Pharmaceutical formulations comprising human insulin, human C-peptide, and human proinsulin
|
|
CA1176158A
(en)
|
1981-08-27 |
1984-10-16 |
Ronald E. Chance |
Pharmaceutical formulations comprising human insulin and human c-peptide
|
|
DE3274798D1
(en)
|
1981-10-05 |
1987-02-05 |
Nicholas P Plotnikoff |
Process for using endorphins as antitumour agents
|
|
US4461724A
(en)
|
1981-10-28 |
1984-07-24 |
Nippon Zoki Pharmaceutical Co., Ltd. |
Peptide compounds, a process for manufacturing them, pharmaceutical compositions containing them, and methods for treating ulcer and thrombus with them
|
|
GB8314308D0
(en)
|
1983-05-24 |
1983-06-29 |
Matburn Holdings Ltd |
Medical administration devices
|
|
DE3326473A1
(de)
|
1983-07-22 |
1985-01-31 |
Hoechst Ag, 6230 Frankfurt |
Pharmazeutisches mittel zur behandlung des diabetes mellitus
|
|
US4585754A
(en)
*
|
1984-01-09 |
1986-04-29 |
Valcor Scientific, Ltd. |
Stabilization of proteins and peptides by chemical binding with chondroitin
|
|
US4810646A
(en)
*
|
1984-11-28 |
1989-03-07 |
Massachusetts Institute Of Technology |
Glucan compositions and process for preparation thereof
|
|
US5028703A
(en)
*
|
1988-03-11 |
1991-07-02 |
Massachusetts Institute Of Technology |
Glucan composition and process for preparation thereof
|
|
US4992540A
(en)
*
|
1984-11-28 |
1991-02-12 |
Massachusetts Institute Of Technology |
Glucan composition and process for preparation thereof
|
|
US4805811A
(en)
*
|
1985-03-29 |
1989-02-21 |
Aktiebolaget Draco |
Dosage device
|
|
US4668281A
(en)
*
|
1985-05-20 |
1987-05-26 |
E. I. Du Pont De Nemours And Company |
Thiophenesulfonamides
|
|
US5256549A
(en)
|
1986-03-28 |
1993-10-26 |
Chiron Corporation |
Purification of synthetic oligomers
|
|
US4801612A
(en)
*
|
1986-07-03 |
1989-01-31 |
Regents Of The University Of California |
Method of inhibiting inflammatory response
|
|
DE3634952A1
(de)
*
|
1986-10-14 |
1988-04-21 |
Bayer Ag |
Imidazo-pyrrolo-pyridin-derivate
|
|
AT387234B
(de)
|
1987-03-05 |
1988-12-27 |
Vogelbusch Gmbh |
Vorrichtung zur zuechtung von dauerformen insbesondere filamentoeser mikroorganismen
|
|
US4966753A
(en)
|
1987-08-18 |
1990-10-30 |
Molecular Rx, Inc. |
Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms
|
|
US5468481A
(en)
|
1988-06-23 |
1995-11-21 |
Amergen, Inc. |
MHC class II-peptide conjugates useful in ameliorating autoimmunity
|
|
US5225183A
(en)
*
|
1988-12-06 |
1993-07-06 |
Riker Laboratories, Inc. |
Medicinal aerosol formulations
|
|
US5049656A
(en)
|
1988-12-21 |
1991-09-17 |
Board Of Regents Of The University Of Nebraska |
Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques
|
|
US5324844A
(en)
|
1989-04-19 |
1994-06-28 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
GB8909891D0
(en)
|
1989-04-28 |
1989-06-14 |
Riker Laboratories Inc |
Device
|
|
DK0400472T3
(da)
*
|
1989-05-27 |
1996-05-13 |
Sumitomo Pharma |
Fremgangsmåde til fremstilling af polyethylenglycolderivater og modificeret protein
|
|
US5032401A
(en)
|
1989-06-15 |
1991-07-16 |
Alpha Beta Technology |
Glucan drug delivery system and adjuvant
|
|
US5137871A
(en)
|
1989-07-28 |
1992-08-11 |
Regents Of The University Of California |
Treatment to reduce edema for brain and musculature injuries
|
|
YU176089A
(sh)
*
|
1989-09-12 |
1992-09-07 |
Sikirić, Predrag |
Postupak za pripremu supstancije bpc i supstancija bpc
|
|
GB8921222D0
(en)
|
1989-09-20 |
1989-11-08 |
Riker Laboratories Inc |
Medicinal aerosol formulations
|
|
IE67185B1
(en)
|
1990-02-02 |
1996-03-06 |
Fisons Plc |
Propellant compositions
|
|
SG45171A1
(en)
|
1990-03-21 |
1998-01-16 |
Boehringer Ingelheim Int |
Atomising devices and methods
|
|
US5118494A
(en)
*
|
1990-03-23 |
1992-06-02 |
Minnesota Mining And Manufacturing Company |
Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
|
|
US5545719A
(en)
*
|
1990-05-01 |
1996-08-13 |
Neuromedica, Inc. |
Nerve growth peptides
|
|
US5888762A
(en)
*
|
1990-06-05 |
1999-03-30 |
Centre National De La Recherche Scientifique (Cnrs) |
Neurotropic growth factors comprising a homeobox peptide
|
|
CA2083821A1
(en)
|
1990-06-28 |
1991-12-29 |
Keith A. Johnson |
Aerosol drug formulations
|
|
IT1243344B
(it)
|
1990-07-16 |
1994-06-10 |
Promo Pack Sa |
Inalatore plurimonodose per medicamenti in polvere
|
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
|
ES2117045T3
(es)
*
|
1990-12-21 |
1998-08-01 |
Curative Tech Inc |
Peptidos angiogenicos.
|
|
US5475085A
(en)
|
1991-02-07 |
1995-12-12 |
Molecumetics, Ltd. |
Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
|
|
CA2103577A1
(en)
|
1991-02-07 |
1992-08-08 |
Michael Kahn |
Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
|
|
HU222249B1
(hu)
*
|
1991-03-08 |
2003-05-28 |
Amylin Pharmaceuticals Inc. |
Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
|
|
US5938117A
(en)
|
1991-04-24 |
1999-08-17 |
Aerogen, Inc. |
Methods and apparatus for dispensing liquids as an atomized spray
|
|
DE69230613T2
(de)
|
1991-07-02 |
2000-12-28 |
Inhale Inc |
Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
|
|
US5320094A
(en)
*
|
1992-01-10 |
1994-06-14 |
The Johns Hopkins University |
Method of administering insulin
|
|
US5521184A
(en)
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
|
DE4216133A1
(de)
|
1992-05-15 |
1993-11-18 |
Bissendorf Peptide Gmbh |
Anwendung von Urodilatin bei Lungen- und Bronchialerkrankungen
|
|
US5785049A
(en)
*
|
1994-09-21 |
1998-07-28 |
Inhale Therapeutic Systems |
Method and apparatus for dispersion of dry powder medicaments
|
|
US6582728B1
(en)
|
1992-07-08 |
2003-06-24 |
Inhale Therapeutic Systems, Inc. |
Spray drying of macromolecules to produce inhaleable dry powders
|
|
US5817628A
(en)
|
1992-12-02 |
1998-10-06 |
The Rockefeller University |
Dynorphin a suppression of natural killer cell activity
|
|
US5470949A
(en)
|
1992-12-15 |
1995-11-28 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Method for making amino acid glycosides and glycopeptides
|
|
US5672581A
(en)
|
1993-01-29 |
1997-09-30 |
Aradigm Corporation |
Method of administration of insulin
|
|
US5492688A
(en)
*
|
1993-04-28 |
1996-02-20 |
The Center For Innovative Technology |
Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a pharmaceutically acceptable suspending, solubilizing, wetting, emulsifying or lubricating agent
|
|
US6191105B1
(en)
|
1993-05-10 |
2001-02-20 |
Protein Delivery, Inc. |
Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin
|
|
US5359030A
(en)
|
1993-05-10 |
1994-10-25 |
Protein Delivery, Inc. |
Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
|
|
US5446128A
(en)
*
|
1993-06-18 |
1995-08-29 |
The Board Of Trustees Of The University Of Illinois |
Alpha-helix mimetics and methods relating thereto
|
|
WO1995000162A1
(en)
|
1993-06-21 |
1995-01-05 |
Enzon, Inc. |
Site specific synthesis of conjugated peptides
|
|
US5804558A
(en)
|
1993-07-20 |
1998-09-08 |
University Of California |
Protegrins
|
|
US6653442B1
(en)
|
1993-07-20 |
2003-11-25 |
Intrabiotics Pharmaceuticals, Inc. |
Protegrins
|
|
IS1736B
(is)
|
1993-10-01 |
1999-12-30 |
Astra Ab |
Aðferð og tæki sem stuðla að aukinni samloðun agna
|
|
IT1271486B
(it)
|
1993-10-12 |
1997-05-28 |
Italfarmaco Spa |
Oligopeptidi immunomodulatori derivati di frammenti della proteina c- reattiva
|
|
US5880131A
(en)
|
1993-10-20 |
1999-03-09 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5840900A
(en)
|
1993-10-20 |
1998-11-24 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5388572A
(en)
*
|
1993-10-26 |
1995-02-14 |
Tenax Corporation (A Connecticut Corp.) |
Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
|
|
US5457044A
(en)
|
1993-10-29 |
1995-10-10 |
Genentech, Inc. |
Method for collection of aerosolized proteins by inert filtration
|
|
US5446090A
(en)
|
1993-11-12 |
1995-08-29 |
Shearwater Polymers, Inc. |
Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
|
|
DE69424181T2
(de)
|
1993-12-20 |
2000-10-19 |
Minnesota Mining And Mfg. Co., Saint Paul |
Flunisolide aerosolformulierungen
|
|
US6051256A
(en)
|
1994-03-07 |
2000-04-18 |
Inhale Therapeutic Systems |
Dispersible macromolecule compositions and methods for their preparation and use
|
|
BR9507023A
(pt)
|
1994-03-07 |
1997-09-23 |
Inhale Therapeutic Syst |
Processos para aerossolização de uma dose de insulina para a liberação respiratória de insulina e para preparação de uma composição de insulina e composição de insulina
|
|
US5629384A
(en)
|
1994-05-17 |
1997-05-13 |
Consiglio Nazionale Delle Ricerche |
Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces
|
|
US5650234A
(en)
|
1994-09-09 |
1997-07-22 |
Surface Engineering Technologies, Division Of Innerdyne, Inc. |
Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces
|
|
US5522385A
(en)
*
|
1994-09-27 |
1996-06-04 |
Aradigm Corporation |
Dynamic particle size control for aerosolized drug delivery
|
|
US5693609A
(en)
*
|
1994-11-17 |
1997-12-02 |
Eli Lilly And Company |
Acylated insulin analogs
|
|
US6379670B1
(en)
|
1994-11-18 |
2002-04-30 |
Neurocrine Biosciences, Inc. |
Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
|
|
US5932462A
(en)
*
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
|
US5834590A
(en)
|
1995-02-22 |
1998-11-10 |
Eastern Virginia Medical School Of The Medical College Of Hampton Roads |
Ingap protein involved in pancreatic islet neogenesis
|
|
US6085740A
(en)
*
|
1996-02-21 |
2000-07-11 |
Aerogen, Inc. |
Liquid dispensing apparatus and methods
|
|
US5758637A
(en)
*
|
1995-08-31 |
1998-06-02 |
Aerogen, Inc. |
Liquid dispensing apparatus and methods
|
|
US6014970A
(en)
*
|
1998-06-11 |
2000-01-18 |
Aerogen, Inc. |
Methods and apparatus for storing chemical compounds in a portable inhaler
|
|
US6205999B1
(en)
*
|
1995-04-05 |
2001-03-27 |
Aerogen, Inc. |
Methods and apparatus for storing chemical compounds in a portable inhaler
|
|
CA2218074C
(en)
|
1995-04-14 |
2002-10-08 |
Mohammed Eljamal |
Powdered pharmaceutical formulations having improved dispersibility
|
|
US6309671B1
(en)
|
1995-04-14 |
2001-10-30 |
Inhale Therapeutic Systems |
Stable glassy state powder formulations
|
|
US5692095A
(en)
|
1995-05-10 |
1997-11-25 |
Allports, Inc. |
Capillary feed boiler
|
|
US6585509B2
(en)
*
|
1995-05-10 |
2003-07-01 |
Allports Llc International |
Vaporization and pressurization of liquid in a porous material
|
|
US6162046A
(en)
|
1995-05-10 |
2000-12-19 |
Allports Llc International |
Liquid vaporization and pressurization apparatus and methods
|
|
KR100459984B1
(ko)
|
1995-06-07 |
2005-06-20 |
아피맥스 테크놀로지스, 엔.브이. |
에리트로포이에틴수용체(epo-r)에결합하는화합물및펩티드
|
|
US5654007A
(en)
|
1995-06-07 |
1997-08-05 |
Inhale Therapeutic Systems |
Methods and system for processing dispersible fine powders
|
|
US5795864A
(en)
|
1995-06-27 |
1998-08-18 |
Neurex Corporation |
Stable omega conopetide formulations
|
|
US5672662A
(en)
*
|
1995-07-07 |
1997-09-30 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
|
|
DE19536902A1
(de)
|
1995-10-04 |
1997-04-10 |
Boehringer Ingelheim Int |
Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
|
|
US5929237A
(en)
*
|
1995-10-27 |
1999-07-27 |
Molecumetics Ltd. |
Reverse-turn mimetics and methods relating thereto
|
|
US5840833A
(en)
|
1995-10-27 |
1998-11-24 |
Molecumetics, Ltd |
Alpha-helix mimetics and methods relating thereto
|
|
US5610136A
(en)
*
|
1996-01-30 |
1997-03-11 |
Milkhaus Laboratory, Inc. |
Method for treatment of benign prostatic hypertrophy
|
|
US5826633A
(en)
|
1996-04-26 |
1998-10-27 |
Inhale Therapeutic Systems |
Powder filling systems, apparatus and methods
|
|
DE19628705A1
(de)
*
|
1996-07-08 |
1998-01-15 |
Fresenius Ag |
Neue Sauerstoff-Transport-Mittel, diese enthaltende Hämoglobin-Hydroxyethylstärke-Konjugate, Verfahren zu deren Herstellung, sowie deren Verwendung als Blutersatzstoffe
|
|
IL119029A0
(en)
*
|
1996-08-07 |
1996-11-14 |
Yeda Res & Dev |
Long-acting drugs and pharamaceutical compositions comprising them
|
|
US6214966B1
(en)
*
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
SE520392C2
(sv)
|
1996-09-27 |
2003-07-01 |
Creative Peptides Sweden Ab C |
Specifika peptider för behandling av diabetes mellitus
|
|
JP2001507701A
(ja)
|
1996-12-31 |
2001-06-12 |
インヘイル・セラピューティック・システムズ・インコーポレーテッド |
親水性賦形剤を有する疎水性薬剤の溶液を噴霧乾燥するための方法及びその方法によって作製された組成物
|
|
US5990237A
(en)
|
1997-05-21 |
1999-11-23 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
|
|
CN1195776C
(zh)
|
1997-09-08 |
2005-04-06 |
新陈代谢药物有限公司 |
肥胖症的治疗
|
|
JP4526702B2
(ja)
|
1997-09-29 |
2010-08-18 |
ネクター セラピューティックス |
安定化生物活性処方物およびその使用方法
|
|
US6448369B1
(en)
|
1997-11-06 |
2002-09-10 |
Shearwater Corporation |
Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation
|
|
EP1411075B1
(en)
*
|
1998-03-12 |
2008-07-02 |
Nektar Therapeutics Al, Corporation |
Method for preparing polymer conjugates
|
|
BR9909492A
(pt)
*
|
1998-04-08 |
2000-12-12 |
Lilly Co Eli |
Liberação pulmonar e nasal de raloxifeno
|
|
US5932548A
(en)
|
1998-06-03 |
1999-08-03 |
Deghenghi; Romano |
Lysine containing peptides for treatment of heart disease
|
|
US6257233B1
(en)
*
|
1998-06-04 |
2001-07-10 |
Inhale Therapeutic Systems |
Dry powder dispersing apparatus and methods for their use
|
|
AU4729199A
(en)
*
|
1998-06-29 |
2000-01-17 |
Center For Blood Research, Inc., The |
Monocyte locomotion inhibitory factor
|
|
GB9814527D0
(en)
|
1998-07-03 |
1998-09-02 |
Cyclacel Ltd |
Delivery system
|
|
DE19835346A1
(de)
|
1998-08-05 |
2000-02-10 |
Boehringer Ingelheim Pharma |
Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
|
|
US6703381B1
(en)
|
1998-08-14 |
2004-03-09 |
Nobex Corporation |
Methods for delivery therapeutic compounds across the blood-brain barrier
|
|
JP4486187B2
(ja)
*
|
1998-10-27 |
2010-06-23 |
武田薬品工業株式会社 |
新規g蛋白質共役型レセプター蛋白質、そのdnaおよびそのリガンド
|
|
JP2002530059A
(ja)
|
1998-11-13 |
2002-09-17 |
サイクラセル・リミテッド |
輸送ベクター
|
|
AU777167B2
(en)
|
1999-04-23 |
2004-10-07 |
Battelle Memorial Institute |
Directionally controlled EHD aerosol sprayer
|
|
US7169889B1
(en)
*
|
1999-06-19 |
2007-01-30 |
Biocon Limited |
Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
|
|
US6579968B1
(en)
|
1999-06-29 |
2003-06-17 |
Palatin Technologies, Inc. |
Compositions and methods for treatment of sexual dysfunction
|
|
SE9902627D0
(sv)
|
1999-07-08 |
1999-07-08 |
Siemens Elema Ab |
Medical nebulizer
|
|
US6323311B1
(en)
|
1999-09-22 |
2001-11-27 |
University Of Utah Research Foundation |
Synthesis of insulin derivatives
|
|
US6376470B1
(en)
|
1999-09-23 |
2002-04-23 |
Enzon, Inc. |
Polymer conjugates of ara-C and ara-C derivatives
|
|
JP4027663B2
(ja)
|
1999-10-04 |
2007-12-26 |
ネクター セラピューティックス エイエル,コーポレイション |
ポリマー安定化神経ペプチド
|
|
DE19951471A1
(de)
|
1999-10-26 |
2001-05-03 |
Forssmann Wolf Georg |
Verwendung von Urodilatin zur Behandlung chronischer Niereninsuffizienz mit Nierenrestfunktionen
|
|
EP1223915B1
(en)
*
|
1999-10-29 |
2005-12-21 |
Nektar Therapeutics |
Dry powder compositions having improved dispersivity
|
|
AUPQ387599A0
(en)
|
1999-11-05 |
1999-12-02 |
Metabolic Pharmaceuticals Limited |
Product and method for control of obesity
|
|
US6348558B1
(en)
|
1999-12-10 |
2002-02-19 |
Shearwater Corporation |
Hydrolytically degradable polymers and hydrogels made therefrom
|
|
CA2394404A1
(en)
*
|
1999-12-17 |
2001-06-21 |
Takeda Chemical Industries, Ltd. |
Process for producing kiss-1 peptide
|
|
US6407211B1
(en)
*
|
1999-12-17 |
2002-06-18 |
Mayo Foundation For Medical Education And Research |
Chimeric natriuretic peptides
|
|
AU781729B2
(en)
*
|
1999-12-22 |
2005-06-09 |
Nektar Therapeutics |
Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
|
|
DE60026073T2
(de)
|
1999-12-22 |
2006-09-28 |
Nektar Therapeutics Al, Corp., Huntsville |
Sterisch gehinderte derivate von wasserlöslichen polymeren
|
|
US6413507B1
(en)
*
|
1999-12-23 |
2002-07-02 |
Shearwater Corporation |
Hydrolytically degradable carbamate derivatives of poly (ethylene glycol)
|
|
AU2001238595A1
(en)
|
2000-02-22 |
2001-09-03 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
|
CA2404257A1
(en)
|
2000-03-30 |
2001-10-11 |
Takeda Chemical Industries, Ltd. |
Novel protein, dna thereof and process for producing the same
|
|
US6884778B2
(en)
*
|
2000-04-14 |
2005-04-26 |
William Marsh Rice University |
Biocompatible macromers
|
|
US7971588B2
(en)
|
2000-05-05 |
2011-07-05 |
Novartis Ag |
Methods and systems for operating an aerosol generator
|
|
EP1297839A4
(en)
|
2000-06-23 |
2005-12-07 |
Kaken Pharma Co Ltd |
PREVENTIVA OR THERAPEUTIC AGAINST HEART FAILURE
|
|
US6357490B1
(en)
*
|
2000-08-22 |
2002-03-19 |
Advanced Inhalation Research, Inc. |
System, method and apparatus for filling containers
|
|
US6770620B2
(en)
|
2000-09-18 |
2004-08-03 |
Sanos Bioscience A/S |
Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
|
|
US20020065397A1
(en)
*
|
2000-10-12 |
2002-05-30 |
Joseph Roberts |
Protecting therapeutic compositions from host-mediated inactivation
|
|
CN101584867A
(zh)
|
2000-10-31 |
2009-11-25 |
瑟莫迪克斯药品公司 |
提高生物活性分子传递的方法和组合物
|
|
US7060675B2
(en)
*
|
2001-02-15 |
2006-06-13 |
Nobex Corporation |
Methods of treating diabetes mellitus
|
|
WO2002085399A1
(fr)
|
2001-04-20 |
2002-10-31 |
Takeda Chemical Industries, Ltd. |
Preparations contenant un peptide
|
|
US6583408B2
(en)
*
|
2001-05-18 |
2003-06-24 |
Battelle Memorial Institute |
Ionization source utilizing a jet disturber in combination with an ion funnel and method of operation
|
|
US6803565B2
(en)
|
2001-05-18 |
2004-10-12 |
Battelle Memorial Institute |
Ionization source utilizing a multi-capillary inlet and method of operation
|
|
OA13136A
(en)
|
2001-05-21 |
2006-12-13 |
Nektar Therapeutics |
Pulmonary administration of chemically modified insulin.
|
|
US20030051728A1
(en)
*
|
2001-06-05 |
2003-03-20 |
Lloyd Peter M. |
Method and device for delivering a physiologically active compound
|
|
US6835802B2
(en)
|
2001-06-04 |
2004-12-28 |
Nobex Corporation |
Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
|
|
US6828297B2
(en)
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
|
US6858580B2
(en)
*
|
2001-06-04 |
2005-02-22 |
Nobex Corporation |
Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
|
US6770625B2
(en)
*
|
2001-09-07 |
2004-08-03 |
Nobex Corporation |
Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
|
|
US7312192B2
(en)
|
2001-09-07 |
2007-12-25 |
Biocon Limited |
Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
|
DE60219645T2
(de)
|
2001-09-19 |
2007-08-09 |
Takeda Pharmaceutical Co. Ltd. |
Antikörper gegen metastin und dessen verwendung zur diagnose von schwangerschaft
|
|
UA78726C2
(en)
*
|
2001-11-01 |
2007-04-25 |
Sciclone Pharmaceuticals Inc |
Pharmaceutical composition of thymosin alpha 1 conjugated with polyethylene glycol, method for production, and method for treatment
|
|
EP1446438A2
(en)
*
|
2001-11-07 |
2004-08-18 |
Nektar Therapeutics Al, Corporation |
Branched polymers and their conjugates
|
|
WO2003044526A1
(en)
|
2001-11-16 |
2003-05-30 |
Waters Investments Limited |
Parallel concentration, desalting and deposition onto maldi targets
|
|
US6701922B2
(en)
*
|
2001-12-20 |
2004-03-09 |
Chrysalis Technologies Incorporated |
Mouthpiece entrainment airflow control for aerosol generators
|
|
US7458373B2
(en)
|
2002-01-15 |
2008-12-02 |
Philip Morris Usa Inc. |
Aerosol generator for drug formulation
|
|
ES2304501T3
(es)
|
2002-02-15 |
2008-10-16 |
Nektar Therapeutics Al, Corporation |
Polimeros a base de oxido de alquileno degradables hidroliticamente.
|
|
US6634864B1
(en)
|
2002-02-19 |
2003-10-21 |
Vapore, Inc. |
High fluid flow and pressure in a capillary pump for vaporization of liquid
|
|
US7431570B2
(en)
|
2002-02-19 |
2008-10-07 |
Vapore, Inc. |
Capillary pumps for vaporization of liquids
|
|
PL205811B1
(pl)
|
2002-08-13 |
2010-05-31 |
Iwona Bonney |
Zastosowanie peptydów o działaniu analgetycznym jako substancji czynnej w urządzeniach do podawania leku bezpośrednio do miejsca ich spodziewanego działania przeciwbólowego
|
|
EP1546235B1
(en)
*
|
2002-09-09 |
2021-10-20 |
Nektar Therapeutics |
Water-soluble polymer alkanals
|
|
WO2004024761A1
(en)
*
|
2002-09-11 |
2004-03-25 |
Fresenius Kabi Deutschland Gmbh |
Hasylated polypeptides, especially hasylated erythropoietin
|
|
DE10242076A1
(de)
*
|
2002-09-11 |
2004-03-25 |
Fresenius Kabi Deutschland Gmbh |
HAS-Allergen-Konjugate
|
|
CN101139393B
(zh)
|
2002-09-12 |
2010-11-24 |
肿瘤疗法科学股份有限公司 |
Kdr肽和包括该肽的疫苗
|
|
BR0316560A
(pt)
*
|
2002-11-26 |
2005-10-04 |
Nobex Corp |
Conjugado de composto natriurético, formulação farmacêutica, método de tratar uma condição, método de preparação do conjugado de composto natriurético, conjugado de peptìdeo pró-polinatriurético modificado, análogo de peptìdeo natriurético, análogo de hbnp, composto, e, método de preparar um composto
|
|
US7648962B2
(en)
*
|
2002-11-26 |
2010-01-19 |
Biocon Limited |
Natriuretic compounds, conjugates, and uses thereof
|
|
DK1667708T5
(da)
*
|
2002-12-26 |
2012-11-12 |
Mountain View Pharmaceuticals |
Polyethylenglycolkonjugater af interferon-beta-1b med forøget biologisk styrke in vitro
|
|
TWI364295B
(en)
|
2002-12-26 |
2012-05-21 |
Mountain View Pharmaceuticals |
Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity
|
|
DE602004029646D1
(en)
|
2003-01-06 |
2010-12-02 |
Nektar Therapeutics San Carlos |
Thiolselektive wasserlösliche polymerderivate
|
|
US6800611B2
(en)
|
2003-01-06 |
2004-10-05 |
Takeda Chemical Industries, Ltd. |
Metastin derivatives and their use
|
|
JP2007525425A
(ja)
*
|
2003-03-24 |
2007-09-06 |
ノボ ノルディスク アクティーゼルスカブ |
Glp−2誘導体
|
|
EP1620118B1
(en)
*
|
2003-04-08 |
2014-06-18 |
Yeda Research And Development Co., Ltd. |
Reversible pegylated drugs
|
|
EP2599502B1
(en)
|
2003-04-11 |
2017-03-01 |
Antriabio, Inc. |
Method for preparation of site-specific protein conjugates
|
|
US20070036744A1
(en)
|
2003-04-23 |
2007-02-15 |
Sciclone Pharmaceuticals, Inc. |
Treatment or prevention of respiratory viral infections with alpha thymosin peptides
|
|
KR101128320B1
(ko)
|
2003-05-23 |
2012-04-12 |
넥타르 테라퓨틱스 |
아미도카르보네이트 연결기를 갖는 peg 유도체
|
|
US20050074425A1
(en)
*
|
2003-07-02 |
2005-04-07 |
Polycord, Inc. |
Method for delivering polymerized therapeutic agent compositions and compositions thereof
|
|
WO2005014024A2
(en)
*
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of a polymer and a protein linked by an oxime linking group
|
|
RU2327703C2
(ru)
|
2003-08-12 |
2008-06-27 |
Лайпоксен Текнолоджиз Лимитед |
Производные полисиаловой кислоты
|
|
KR101200729B1
(ko)
|
2003-09-17 |
2012-11-13 |
넥타르 테라퓨틱스 |
다분지형 고분자 전구약물
|
|
CA2930900C
(en)
|
2003-10-02 |
2018-10-16 |
Jazz Pharmaceuticals International Limited |
Combinations of ziconotide and opioids for reducing pain
|
|
EP2239273B1
(en)
*
|
2003-11-13 |
2013-10-09 |
Hanmi Science Co., Ltd. |
A pharmaceutical composition comprosing an immunoglobulin fc as a carrier
|
|
CA2940803A1
(en)
|
2004-03-23 |
2005-10-27 |
Ascendis Pharma Gmbh |
Prodrug linker
|
|
US7803764B2
(en)
|
2004-03-29 |
2010-09-28 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Amphipathic glycopeptides
|
|
US7290541B2
(en)
|
2004-04-20 |
2007-11-06 |
Aerogen, Inc. |
Aerosol delivery apparatus and method for pressure-assisted breathing systems
|
|
US7946291B2
(en)
|
2004-04-20 |
2011-05-24 |
Novartis Ag |
Ventilation systems and methods employing aerosol generators
|
|
EP1750513A4
(en)
|
2004-04-23 |
2009-07-22 |
Serono Lab |
USE OF GPCR54 LIGANDS FOR THE TREATMENT OF BARRENESS
|
|
CN100355786C
(zh)
|
2004-04-28 |
2007-12-19 |
江苏豪森药业股份有限公司 |
聚乙二醇修饰的胸腺肽1衍生物
|
|
US7740861B2
(en)
|
2004-06-16 |
2010-06-22 |
University Of Massachusetts |
Drug delivery product and methods
|
|
DE602005025355D1
(de)
|
2004-07-16 |
2011-01-27 |
Nektar Therapeutics San Carlos |
Konjugate enthaltend gm-csf und ein polymer
|
|
EP1838331A4
(en)
|
2004-12-15 |
2012-12-26 |
Univ Colorado |
ANTIMICROBIAL PEPTIDES AND METHOD OF USE
|
|
US20080207505A1
(en)
|
2005-01-12 |
2008-08-28 |
James Kenneth D |
Bna Conjugates and Methods of Use
|
|
GB0501008D0
(en)
|
2005-01-18 |
2005-02-23 |
Amura Therapeutics Ltd |
Method of producing conjugate vaccines
|
|
TWI376234B
(en)
|
2005-02-01 |
2012-11-11 |
Msd Oss Bv |
Conjugates of a polypeptide and an oligosaccharide
|
|
US7393833B2
(en)
|
2005-03-09 |
2008-07-01 |
The Board Of Regents Of The University Of Oklahoma |
Chimeric proteins with phosphatidylserine binding domains
|
|
EP1863840A1
(en)
|
2005-03-18 |
2007-12-12 |
Novo Nordisk A/S |
Pegylated single-chain insulin
|
|
PT2510942E
(pt)
|
2005-04-07 |
2015-12-28 |
Cardiorentis Ag |
Utilização de péptido natriurético para o tratamento de insuficiência cardíaca
|
|
EP1885403B1
(en)
*
|
2005-04-12 |
2013-05-08 |
Nektar Therapeutics |
Poly(ethyleneglycol) conjugates of Lysostaphin
|
|
US7833979B2
(en)
*
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
|
ES2514470T3
(es)
|
2005-05-25 |
2014-10-28 |
Aerogen, Inc. |
Sistemas y métodos de vibración
|
|
WO2006138572A2
(en)
*
|
2005-06-16 |
2006-12-28 |
Nektar Therapeutics Al, Corporation |
Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
|
|
EP1937716A2
(en)
|
2005-09-08 |
2008-07-02 |
Uutech Limited |
Analogs of gastric inhibitory polypeptide as a treatment for age related decreased pancreatic beta cell function
|
|
US20090035287A1
(en)
*
|
2005-09-26 |
2009-02-05 |
Zurit Levine |
Atrial natriuretic peptide (anp) splice variants and methods of using same
|
|
CN100577685C
(zh)
|
2005-11-10 |
2010-01-06 |
中国人民解放军军事医学科学院毒物药物研究所 |
长效胸腺素α1的聚乙二醇化修饰物
|
|
EP1797901A1
(en)
|
2005-12-16 |
2007-06-20 |
Diatos |
Cell penetrating peptide conjugates for delivering nucleic acids into cells
|
|
US8293869B2
(en)
*
|
2005-12-16 |
2012-10-23 |
Nektar Therapeutics |
Polymer conjugates of GLP-1
|
|
EP2001500A4
(en)
|
2006-03-10 |
2010-07-28 |
Dyax Corp |
FORMULATIONS FOR ECALLANTIDE
|
|
US20080044438A1
(en)
*
|
2006-03-17 |
2008-02-21 |
Ostroff Gary R |
Yeast Cell Particles As Oral Delivery Vehicles For Antigens
|
|
EP2038424A2
(en)
|
2006-06-21 |
2009-03-25 |
Enzon Pharmaceuticals, Inc. |
Stabilized proteins
|
|
WO2008011165A2
(en)
*
|
2006-07-21 |
2008-01-24 |
Nektar Therapeutics Al, Corporation |
Polymeric reagents comprising a terminal vinylic group and conjugates formed therefrom
|
|
EP1900742A1
(en)
*
|
2006-09-07 |
2008-03-19 |
AEterna Zentaris GmbH |
Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof
|
|
JP5421109B2
(ja)
|
2006-09-13 |
2014-02-19 |
ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク |
低カルボキシル化/非カルボキシル化オステオカルシンはベータ細胞増殖、インスリン分泌、インスリン感受性、耐糖能を増加させ、体脂肪量を減少させる
|
|
JP2008156283A
(ja)
*
|
2006-12-25 |
2008-07-10 |
Kyowa Hakko Kogyo Co Ltd |
水溶性ポリマー修飾ポリペプチドの製造方法
|
|
WO2008082669A2
(en)
*
|
2006-12-27 |
2008-07-10 |
Nektar Therapeutics Al, Corporation |
Von willebrand factor- and factor viii-polymer conjugates having a releasable linkage
|
|
RU2007137048A
(ru)
|
2007-10-05 |
2009-04-10 |
Общество С Ограниченной Ответственностью "Концерн О3" (Ru) |
Лекарственное средство для лечения и предупреждения осложнений при сахарном диабете
|
|
EP2209494B1
(en)
|
2007-10-09 |
2016-07-20 |
Polytherics Limited |
Novel conjugated proteins and peptides
|
|
EP2070950A1
(en)
*
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Hydroxyalkyl starch derivatives and process for their preparation
|
|
WO2010033204A2
(en)
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of c-peptides
|
|
WO2010033221A1
(en)
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of protegrin peptides
|
|
WO2010042145A1
(en)
|
2008-09-19 |
2010-04-15 |
Nektar Therapeutics |
Polymer conjugates of glp-2-like peptides
|
|
US8449872B2
(en)
*
|
2008-09-19 |
2013-05-28 |
Nektar Therapeutics |
Polymer conjugates of nesiritide peptides
|
|
US20110171166A1
(en)
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of osteocalcin peptides
|
|
US20110166063A1
(en)
|
2008-09-19 |
2011-07-07 |
Nektar Therapeutics |
Polymer conjugates of therapeutic peptides
|
|
US20110171163A1
(en)
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of ziconotide peptides
|
|
WO2010033227A1
(en)
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of thymosin alpha 1 peptides
|
|
US20110171160A1
(en)
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of kiss1 peptides
|
|
EP2334337A1
(en)
|
2008-09-19 |
2011-06-22 |
Nektar Therapeutics |
Polymer conjugates of opioid growth factor peptides
|
|
EP2344200A2
(en)
|
2008-09-19 |
2011-07-20 |
Nektar Therapeutics |
Modified therapeutics peptides, methods of their preparation and use
|
|
US20120195847A1
(en)
|
2008-09-19 |
2012-08-02 |
Nektar Therapeutics |
Polymer conjugates of biphalin peptides
|
|
EP2334333A1
(en)
|
2008-09-19 |
2011-06-22 |
Nektar Therapeutics |
Polymer conjugates of v681-like peptides
|
|
US20110237524A1
(en)
|
2008-09-19 |
2011-09-29 |
Nektar Therapeutics |
Polymer conjugates of aod-like peptides
|