JP2018510863A5 - - Google Patents

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Publication number
JP2018510863A5
JP2018510863A5 JP2017547157A JP2017547157A JP2018510863A5 JP 2018510863 A5 JP2018510863 A5 JP 2018510863A5 JP 2017547157 A JP2017547157 A JP 2017547157A JP 2017547157 A JP2017547157 A JP 2017547157A JP 2018510863 A5 JP2018510863 A5 JP 2018510863A5
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JP
Japan
Prior art keywords
water soluble
conjugate
moiety
soluble polymer
conjugate according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2017547157A
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English (en)
Japanese (ja)
Other versions
JP2018510863A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/022146 external-priority patent/WO2016145388A1/en
Publication of JP2018510863A publication Critical patent/JP2018510863A/ja
Publication of JP2018510863A5 publication Critical patent/JP2018510863A5/ja
Priority to JP2022129624A priority Critical patent/JP2022163194A/ja
Withdrawn legal-status Critical Current

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JP2017547157A 2015-03-11 2016-03-11 Il−7部分とポリマーとのコンジュゲート Withdrawn JP2018510863A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022129624A JP2022163194A (ja) 2015-03-11 2022-08-16 Il-7部分とポリマーとのコンジュゲート

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562131634P 2015-03-11 2015-03-11
US62/131,634 2015-03-11
PCT/US2016/022146 WO2016145388A1 (en) 2015-03-11 2016-03-11 Conjugates of an il-7 moiety and an polymer

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2021031726A Division JP2021091708A (ja) 2015-03-11 2021-03-01 Il−7部分とポリマーとのコンジュゲート
JP2022129624A Division JP2022163194A (ja) 2015-03-11 2022-08-16 Il-7部分とポリマーとのコンジュゲート

Publications (2)

Publication Number Publication Date
JP2018510863A JP2018510863A (ja) 2018-04-19
JP2018510863A5 true JP2018510863A5 (enExample) 2019-04-18

Family

ID=56878892

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017547157A Withdrawn JP2018510863A (ja) 2015-03-11 2016-03-11 Il−7部分とポリマーとのコンジュゲート
JP2021031726A Pending JP2021091708A (ja) 2015-03-11 2021-03-01 Il−7部分とポリマーとのコンジュゲート
JP2022129624A Pending JP2022163194A (ja) 2015-03-11 2022-08-16 Il-7部分とポリマーとのコンジュゲート

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021031726A Pending JP2021091708A (ja) 2015-03-11 2021-03-01 Il−7部分とポリマーとのコンジュゲート
JP2022129624A Pending JP2022163194A (ja) 2015-03-11 2022-08-16 Il-7部分とポリマーとのコンジュゲート

Country Status (11)

Country Link
US (1) US12629407B2 (enExample)
EP (1) EP3285799A4 (enExample)
JP (3) JP2018510863A (enExample)
KR (2) KR20170125839A (enExample)
CN (1) CN107405384A (enExample)
AU (1) AU2016228555B2 (enExample)
CA (1) CA2978330C (enExample)
IL (1) IL254389B2 (enExample)
MA (1) MA41957A (enExample)
MX (1) MX391071B (enExample)
WO (1) WO2016145388A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052686B2 (en) 2000-09-29 2006-05-30 Schering Corporation Pegylated interleukin-10
NZ597098A (en) 2006-09-28 2013-05-31 Merck Sharp & Dohme Use of pegylated il-10 to treat cancer
EP2986306A4 (en) 2013-04-18 2016-12-07 Armo Biosciences Inc METHOD FOR USE OF INTERLEUKIN-10 FOR THE TREATMENT OF ILLNESSES AND SUFFERING
CA2914837A1 (en) 2013-06-17 2014-12-24 Armo Biosciences, Inc. Method for assessing protein identity and stability
KR20160079114A (ko) 2013-11-11 2016-07-05 아르모 바이오사이언시스 인코포레이티드 질환 및 장애를 치료하기 위한 인터류킨-10을 사용하는 방법
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
AU2015336101A1 (en) 2014-10-22 2017-04-20 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10618970B2 (en) 2015-02-03 2020-04-14 Armo Biosciences, Inc. Method of treating cancer with IL-10 and antibodies that induce ADCC
WO2016191587A1 (en) 2015-05-28 2016-12-01 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
CA2995120A1 (en) 2015-08-25 2017-03-02 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US11702446B2 (en) 2018-12-12 2023-07-18 Levim Biotech Llp Acylation process for preparation of N-substituted peptide
WO2022020637A1 (en) * 2020-07-22 2022-01-27 Nektar Therapeutics Il-7 receptor agonist composition and related methods and uses
WO2023064793A1 (en) * 2021-10-14 2023-04-20 Allegheny Singer Research Institute Interleukin 7 and interleukin 21 fusion proteins
US20250082777A1 (en) 2022-01-10 2025-03-13 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
WO2023193015A1 (en) 2022-04-01 2023-10-05 Sana Biotechnology, Inc. Cytokine receptor agonist and viral vector combination therapies

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166322A (en) 1989-04-21 1992-11-24 Genetics Institute Cysteine added variants of interleukin-3 and chemical modifications thereof
US5446090A (en) 1993-11-12 1995-08-29 Shearwater Polymers, Inc. Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US5795966A (en) 1995-02-22 1998-08-18 Immunex Corp Antagonists of interleukin-15
CA2323048C (en) 1998-03-12 2006-10-10 Shearwater Polymers, Inc. Poly(ethylene glycol) derivatives with proximal reactive groups
US7666400B2 (en) * 2005-04-06 2010-02-23 Ibc Pharmaceuticals, Inc. PEGylation by the dock and lock (DNL) technique
US6602498B2 (en) 2000-02-22 2003-08-05 Shearwater Corporation N-maleimidyl polymer derivatives
AU2002307497A1 (en) * 2001-04-23 2002-11-05 The Regents Of The University Of California Methods of using interleukin-7 to modulate physiological processes in mammalian pulmonary fibroblasts
OA13063A (en) 2001-11-20 2006-11-10 Pharmacia Corp Chemically-modified human growth hormone conjugates.
EP1391513A1 (en) * 2002-08-08 2004-02-25 Cytheris IL-7 drug substance, IL-7 comprising composition, preparation and uses thereof
RS20050501A (sr) 2002-12-26 2007-08-03 Mountain View Pharmaceuticals Inc., Polimerni konjugati citokina,hemokina,faktora rasta, polipeptidnih hormona i njihovih antagonista sa očuvanom aktivnošću vezivanja receptora
US7910661B2 (en) 2003-01-06 2011-03-22 Nektar Therapeutics Thiol-selective water-soluble polymer derivatives
US7956032B2 (en) 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
CN101072793B (zh) 2004-12-09 2012-06-20 默克专利有限公司 具有降低的免疫原性的il-7变体
CA2611823C (en) 2005-06-16 2013-07-30 Nektar Therapeutics Al, Corporation Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
CN106046370A (zh) 2007-02-28 2016-10-26 塞瑞纳治疗公司 聚噁唑啉poz化合物、合成其的方法、以及靶分子‑poz偶联物
CN102037004A (zh) * 2008-01-08 2011-04-27 生物种属学股份公司 使用寡糖基转移酶的多肽的糖缀合
ES2866674T3 (es) 2010-11-12 2021-10-19 Nektar Therapeutics Conjugados de una fracción de IL-2 y un polímero
CN102145178B (zh) * 2011-04-15 2012-09-26 北京凯因科技股份有限公司 Peg化白介素15
WO2013020079A2 (en) * 2011-08-04 2013-02-07 Nektar Therapeutics Conjugates of an il-11 moiety and a polymer
WO2013074489A1 (en) * 2011-11-14 2013-05-23 Emory University Conjugates of gm-csf and il-7, compositions and methods related thereto

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