JP2014503548A5 - - Google Patents

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Publication number
JP2014503548A5
JP2014503548A5 JP2013546460A JP2013546460A JP2014503548A5 JP 2014503548 A5 JP2014503548 A5 JP 2014503548A5 JP 2013546460 A JP2013546460 A JP 2013546460A JP 2013546460 A JP2013546460 A JP 2013546460A JP 2014503548 A5 JP2014503548 A5 JP 2014503548A5
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JP
Japan
Prior art keywords
water
compound
soluble non
peptide polymer
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013546460A
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English (en)
Japanese (ja)
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JP2014503548A (ja
JP6002149B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/067259 external-priority patent/WO2012088529A1/en
Publication of JP2014503548A publication Critical patent/JP2014503548A/ja
Publication of JP2014503548A5 publication Critical patent/JP2014503548A5/ja
Application granted granted Critical
Publication of JP6002149B2 publication Critical patent/JP6002149B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013546460A 2010-12-23 2011-12-23 ポリマー−スニチニブコンジュゲート Active JP6002149B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061426919P 2010-12-23 2010-12-23
US61/426,919 2010-12-23
PCT/US2011/067259 WO2012088529A1 (en) 2010-12-23 2011-12-23 Polymer-sunitinib conjugates

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016136547A Division JP2016185978A (ja) 2010-12-23 2016-07-11 ポリマー−スニチニブコンジュゲート

Publications (3)

Publication Number Publication Date
JP2014503548A JP2014503548A (ja) 2014-02-13
JP2014503548A5 true JP2014503548A5 (enExample) 2014-12-25
JP6002149B2 JP6002149B2 (ja) 2016-10-05

Family

ID=45529206

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013546460A Active JP6002149B2 (ja) 2010-12-23 2011-12-23 ポリマー−スニチニブコンジュゲート
JP2016136547A Withdrawn JP2016185978A (ja) 2010-12-23 2016-07-11 ポリマー−スニチニブコンジュゲート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016136547A Withdrawn JP2016185978A (ja) 2010-12-23 2016-07-11 ポリマー−スニチニブコンジュゲート

Country Status (4)

Country Link
US (3) US9827326B2 (enExample)
EP (1) EP2654799B1 (enExample)
JP (2) JP6002149B2 (enExample)
WO (1) WO2012088529A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012088506A1 (en) 2010-12-23 2012-06-28 Nektar Therapeutics Polymer-semaxanib moiety conjugates
US10220020B2 (en) 2010-12-23 2019-03-05 Nektar Therapeutics Polymer-des-ethyl sunitinib conjugates
EP2654799B1 (en) 2010-12-23 2017-11-08 Nektar Therapeutics Polymer-sunitinib conjugates
AU2015355965B2 (en) * 2014-12-04 2019-07-04 Delta-Fly Pharma, Inc. Novel PEG derivative
CN104610231B (zh) * 2015-01-28 2016-08-17 广州葳澜生物科技有限公司 一种舒尼替尼前药
KR20180058758A (ko) 2015-09-22 2018-06-01 그레이버그 비젼, 인크. 안구 장애의 치료를 위한 화합물 및 조성물
EP3600324A4 (en) 2017-03-23 2020-12-09 Graybug Vision, Inc. COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS
MX2019013363A (es) 2017-05-10 2020-01-13 Graybug Vision Inc Microparticulas de liberacion extendida y suspensiones de las mismas para terapia medica.
CN113490765A (zh) * 2019-03-08 2021-10-08 应用材料公司 用于处理腔室的多孔喷头

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US4992540A (en) 1984-11-28 1991-02-12 Massachusetts Institute Of Technology Glucan composition and process for preparation thereof
US4810646A (en) 1984-11-28 1989-03-07 Massachusetts Institute Of Technology Glucan compositions and process for preparation thereof
US5032401A (en) 1989-06-15 1991-07-16 Alpha Beta Technology Glucan drug delivery system and adjuvant
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
PT1255536E (pt) 1999-12-22 2006-09-29 Sugen Inc Derivados de indolinona para a modulacao da tirosina proteina cinase de tipo c-kit
DE122008000002I1 (de) * 2000-02-15 2008-04-17 Sugen Inc Pyrrol substituierte indolin-2-on protein kinase inhibitoren
AU2001255796A1 (en) 2000-05-02 2001-11-12 Sugen, Inc. (2-oxindol-3-ylidenyl)acetic acid derivatives and their use as protein kinase inhibitors
TWI270545B (en) 2000-05-24 2007-01-11 Sugen Inc Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
TWI259081B (en) 2001-10-26 2006-08-01 Sugen Inc Treatment of acute myeloid leukemia with indolinone compounds
EP1446438A2 (en) 2001-11-07 2004-08-18 Nektar Therapeutics Al, Corporation Branched polymers and their conjugates
US7053144B1 (en) 2002-06-13 2006-05-30 Cmi Rubber Company, Inc. High density rubber compounds
US20050079155A1 (en) 2003-03-20 2005-04-14 Xencor, Inc. Generating protein pro-drugs using reversible PPG linkages
US7887789B2 (en) 2003-05-23 2011-02-15 Nektar Therapeutics Polymer derivatives having particular atom arrangements
EP2626083A1 (en) 2003-09-17 2013-08-14 Nektar Therapeutics Multi-arm polymer prodrugs
US9085659B2 (en) 2004-05-03 2015-07-21 Nektar Therapeutics Polymer derivatives comprising an imide branching point
US8562965B2 (en) 2004-05-03 2013-10-22 Nektar Therapeutics Polymer derivatives comprising an acetal or ketal branching point
US7740861B2 (en) 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
HUE025208T2 (en) 2005-06-16 2016-03-29 Nektar Therapeutics Conjugates with degradable binding and polymer reagents useful in the preparation of such conjugates
EP1986695B1 (en) 2006-02-21 2015-06-03 Nektar Therapeutics Segmented degradable polymers and conjugates made therefrom
WO2007109564A2 (en) 2006-03-17 2007-09-27 University Of Massachusetts Yeast cell particles as oral delivery vehicles for antigens
US8133865B2 (en) 2006-12-27 2012-03-13 Nektar Therapeutics von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage
CN101878042B (zh) 2007-11-28 2013-06-19 尼克塔治疗公司 低聚物-三环共轭物
US8829043B2 (en) 2008-02-08 2014-09-09 Nektar Therapeutics Oligome-cannabinoid conjugates
CA2720760C (en) 2008-04-11 2016-10-11 Nektar Therapeutics Oligomer-aryloxy-substituted propanamine conjugates
WO2009141823A2 (en) * 2008-05-22 2009-11-26 Ramot At Tel Aviv University Ltd. Conjugates of a polymer, a bisphosphonate and an anti-angiogenesis agent and uses thereof in the treatment and monitoring of bone related diseases
JP5588983B2 (ja) 2008-08-11 2014-09-10 ウェルズ ファーゴ バンク ナショナル アソシエイション マルチアームポリマーアルカノエートコンジュゲート
US20120052041A1 (en) 2009-02-04 2012-03-01 The Brigham And Women's Hospital, Inc. Polymeric nanoparticles with enhanced drug-loading and methods of use thereof
US8816077B2 (en) * 2009-04-17 2014-08-26 Nektar Therapeutics Oligomer-protein tyrosine kinase inhibitor conjugates
US20120094998A1 (en) * 2009-04-17 2012-04-19 Nektar Therapeutics Oligomer-Protein Tyrosine Kinase Inhibitor Conjugates
EP2654799B1 (en) 2010-12-23 2017-11-08 Nektar Therapeutics Polymer-sunitinib conjugates
US10220020B2 (en) 2010-12-23 2019-03-05 Nektar Therapeutics Polymer-des-ethyl sunitinib conjugates

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