JP2014503548A5 - - Google Patents

Download PDF

Info

Publication number
JP2014503548A5
JP2014503548A5 JP2013546460A JP2013546460A JP2014503548A5 JP 2014503548 A5 JP2014503548 A5 JP 2014503548A5 JP 2013546460 A JP2013546460 A JP 2013546460A JP 2013546460 A JP2013546460 A JP 2013546460A JP 2014503548 A5 JP2014503548 A5 JP 2014503548A5
Authority
JP
Japan
Prior art keywords
water
compound
soluble non
peptide polymer
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013546460A
Other languages
English (en)
Japanese (ja)
Other versions
JP6002149B2 (ja
JP2014503548A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/067259 external-priority patent/WO2012088529A1/en
Publication of JP2014503548A publication Critical patent/JP2014503548A/ja
Publication of JP2014503548A5 publication Critical patent/JP2014503548A5/ja
Application granted granted Critical
Publication of JP6002149B2 publication Critical patent/JP6002149B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013546460A 2010-12-23 2011-12-23 ポリマー−スニチニブコンジュゲート Active JP6002149B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061426919P 2010-12-23 2010-12-23
US61/426,919 2010-12-23
PCT/US2011/067259 WO2012088529A1 (en) 2010-12-23 2011-12-23 Polymer-sunitinib conjugates

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016136547A Division JP2016185978A (ja) 2010-12-23 2016-07-11 ポリマー−スニチニブコンジュゲート

Publications (3)

Publication Number Publication Date
JP2014503548A JP2014503548A (ja) 2014-02-13
JP2014503548A5 true JP2014503548A5 (enExample) 2014-12-25
JP6002149B2 JP6002149B2 (ja) 2016-10-05

Family

ID=45529206

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013546460A Active JP6002149B2 (ja) 2010-12-23 2011-12-23 ポリマー−スニチニブコンジュゲート
JP2016136547A Withdrawn JP2016185978A (ja) 2010-12-23 2016-07-11 ポリマー−スニチニブコンジュゲート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016136547A Withdrawn JP2016185978A (ja) 2010-12-23 2016-07-11 ポリマー−スニチニブコンジュゲート

Country Status (4)

Country Link
US (3) US9827326B2 (enExample)
EP (1) EP2654799B1 (enExample)
JP (2) JP6002149B2 (enExample)
WO (1) WO2012088529A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6009457B2 (ja) 2010-12-23 2016-10-19 ネクター セラピューティクス ポリマー−デスエチルスニチニブコンジュゲート
US9827326B2 (en) 2010-12-23 2017-11-28 Nektar Therapeutics Polymer-sunitinib conjugates
WO2012088506A1 (en) 2010-12-23 2012-06-28 Nektar Therapeutics Polymer-semaxanib moiety conjugates
EP3228650B1 (en) * 2014-12-04 2022-03-09 Delta-Fly Pharma, Inc. Novel peg derivative
CN104610231B (zh) * 2015-01-28 2016-08-17 广州葳澜生物科技有限公司 一种舒尼替尼前药
KR20180058758A (ko) 2015-09-22 2018-06-01 그레이버그 비젼, 인크. 안구 장애의 치료를 위한 화합물 및 조성물
EP3600324A4 (en) 2017-03-23 2020-12-09 Graybug Vision, Inc. COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS
AU2018265415A1 (en) 2017-05-10 2019-10-31 Graybug Vision, Inc. Extended release microparticles and suspensions thereof for medical therapy
JP7680361B2 (ja) * 2019-03-08 2025-05-20 アプライド マテリアルズ インコーポレイテッド 処理チャンバ用の多孔性シャワーヘッド

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992540A (en) 1984-11-28 1991-02-12 Massachusetts Institute Of Technology Glucan composition and process for preparation thereof
US4810646A (en) 1984-11-28 1989-03-07 Massachusetts Institute Of Technology Glucan compositions and process for preparation thereof
US5028703A (en) 1988-03-11 1991-07-02 Massachusetts Institute Of Technology Glucan composition and process for preparation thereof
US5032401A (en) 1989-06-15 1991-07-16 Alpha Beta Technology Glucan drug delivery system and adjuvant
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
ATE331514T1 (de) 1999-12-22 2006-07-15 Sugen Inc Indolinonderivate zur abänderung der c-kit tyrosinproteinkinase
JP3663382B2 (ja) * 2000-02-15 2005-06-22 スージェン・インコーポレーテッド ピロール置換２−インドリノン蛋白質キナーゼ阻害剤
MXPA02010759A (es) 2000-05-02 2004-07-30 Sugen Inc Derivados del acido (2-oxindol-3-ilidenil) acetico y su uso como inhibidores de la proteina quinasa.
MY128450A (en) 2000-05-24 2007-02-28 Upjohn Co 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
TWI259081B (en) 2001-10-26 2006-08-01 Sugen Inc Treatment of acute myeloid leukemia with indolinone compounds
EP1446438A2 (en) 2001-11-07 2004-08-18 Nektar Therapeutics Al, Corporation Branched polymers and their conjugates
US7053144B1 (en) 2002-06-13 2006-05-30 Cmi Rubber Company, Inc. High density rubber compounds
WO2004084949A2 (en) 2003-03-20 2004-10-07 Xencor Generating protein pro-drugs using reversible ppg linkages
EP2644206B1 (en) 2003-05-23 2019-04-03 Nektar Therapeutics PEG derivatives containing two PEG chains
CA2537336C (en) 2003-09-17 2013-02-26 Nektar Therapeutics Al, Corporation Multi-arm polymer prodrugs
WO2005108463A2 (en) 2004-05-03 2005-11-17 Nektar Therapeutics Al, Corporation Branched polyethylen glycol derivates comprising an acetal or ketal branching point
WO2005107815A2 (en) 2004-05-03 2005-11-17 Nektar Therapeutics Al, Corporation Polymer derivatives comprising an imide branching point
US7740861B2 (en) 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
HUE025208T2 (en) 2005-06-16 2016-03-29 Nektar Therapeutics Conjugates with degradable binding and polymer reagents useful in the preparation of such conjugates
US8309680B2 (en) 2006-02-21 2012-11-13 Nektar Therapeutics Segmented degradable polymers and conjugates made therefrom
US20080044438A1 (en) 2006-03-17 2008-02-21 Ostroff Gary R Yeast Cell Particles As Oral Delivery Vehicles For Antigens
EP2114458B1 (en) 2006-12-27 2014-02-26 Nektar Therapeutics Von willebrand factor- and factor viii-polymer conjugates having a releasable linkage
AU2008331868B2 (en) 2007-11-28 2015-02-12 Nektar Therapeutics Oligomer-tricyclic conjugates
EP2254601B1 (en) 2008-02-08 2019-05-29 Nektar Therapeutics Oligomer-cannabinoid conjugates
WO2009126333A1 (en) 2008-04-11 2009-10-15 Nektar Therapeutics Oligomer-aryloxy-substituted propanamine conjugates
EP2303288A4 (en) * 2008-05-22 2015-04-22 Univ Ramot CONJUGATES OF A POLYMER, A BISPHOSPHONATE AND AN ANTI-ANGIOGENESE MEDIUM AND ITS USE IN THE TREATMENT AND CONTROL OF ILLNESSES RELATED TO BONE
AU2009282413B2 (en) 2008-08-11 2014-07-17 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
WO2010091187A2 (en) 2009-02-04 2010-08-12 The Brigham And Women's Hospital, Inc. Polymeric nanoparticles with enhanced drug-loading and methods of use thereof
WO2010120388A1 (en) * 2009-04-17 2010-10-21 Nektar Therapeutics Oligomer-protein tyrosine kinase inhibitor conjugates
WO2010120387A1 (en) 2009-04-17 2010-10-21 Nektar Therapeutics Oligomer-protein tyrosine kinase inhibitor conjugates
JP6009457B2 (ja) 2010-12-23 2016-10-19 ネクター セラピューティクス ポリマー−デスエチルスニチニブコンジュゲート
US9827326B2 (en) 2010-12-23 2017-11-28 Nektar Therapeutics Polymer-sunitinib conjugates

Similar Documents

Publication Publication Date Title
JP2014503548A5 (enExample)
JP2014501765A5 (enExample)
JP5655147B2 (ja) 治療用ペプチド−ポリマーの複合体、粒子、組成物および関連の方法
JP5312050B2 (ja) 分割型の分解性重合体とそれから生成される複合体
AU2008317383B2 (en) Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom
JP2011080089A5 (enExample)
JP2020514300A5 (enExample)
JP2017511322A5 (enExample)
US20100004390A1 (en) Biodegradable metal-chelating polymers and vaccines
JP2002508400A5 (enExample)
JP2012502904A5 (enExample)
JP2010523582A5 (enExample)
HRP20210642T1 (hr) Konjugati il-2 ostatka i polimera
US20100048736A1 (en) Anionic charge-dynamic polymers for release of cationic agents
SI2068907T1 (en) Glycerol linked pegylated sugars and glycopeptides
EP1480657A1 (en) Polymers for delivering peptides and small molecules i in vivo /i
JP2014058562A5 (enExample)
JP2011509311A5 (enExample)
JP2008542399A5 (enExample)
JP2007504169A5 (enExample)
JP2008266635A5 (ja) 活性エネルギー線硬化型液体組成物、水性インク及び液体カートリッジ
JP2002520288A5 (enExample)
JP2012516347A5 (enExample)
JP2004532301A5 (enExample)
KR20140019214A (ko) 폴리에틸렌글리콜-폴리락트산-폴리에틸렌이민 양이온성 공중합체, 이의 제조방법 및 상기 공중합체를 포함하는 약물 전달용 조성물