ES2425448B8 - Uso de la obestatina para la regeneración muscular - Google Patents
Uso de la obestatina para la regeneración muscular Download PDFInfo
- Publication number
- ES2425448B8 ES2425448B8 ES201230367A ES201230367A ES2425448B8 ES 2425448 B8 ES2425448 B8 ES 2425448B8 ES 201230367 A ES201230367 A ES 201230367A ES 201230367 A ES201230367 A ES 201230367A ES 2425448 B8 ES2425448 B8 ES 2425448B8
- Authority
- ES
- Spain
- Prior art keywords
- muscle regeneration
- obestatine
- regeneration
- muscle
- obestatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000009756 muscle regeneration Effects 0.000 title abstract 3
- OJSXICLEROKMBP-FFUDWAICSA-N 869705-22-6 Chemical compound C([C@@H](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 OJSXICLEROKMBP-FFUDWAICSA-N 0.000 abstract 2
- 102000012004 Ghrelin Human genes 0.000 abstract 2
- 101800001586 Ghrelin Proteins 0.000 abstract 2
- 101800000590 Obestatin Proteins 0.000 abstract 2
- 208000026350 Inborn Genetic disease Diseases 0.000 abstract 1
- 208000029549 Muscle injury Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000016361 genetic disease Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000001114 myogenic effect Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2214—Motilins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Uso de la obestatina para la regeneración muscular.#La presente invención se refiere al uso de la obestatina, o a la secuencia nucleotídica que la codifica, como agente miogénico in vitro, y para la elaboración de un medicamento para la regeneración muscular preferiblemente para la regeneración músculo-esquelética, siendo así de utilidad en el tratamiento y/o prevención de enfermedades degenerativas o genéticas o de lesiones que cursan con daño muscular.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201230367A ES2425448B8 (es) | 2012-03-12 | 2012-03-12 | Uso de la obestatina para la regeneración muscular |
EP13761384.0A EP2862577B1 (en) | 2012-03-12 | 2013-03-08 | Use of obestatin for muscle regeneration |
PCT/ES2013/070149 WO2013135928A1 (es) | 2012-03-12 | 2013-03-08 | Uso de la obestatina para la regeneración muscular |
US14/384,766 US20150094264A1 (en) | 2012-03-12 | 2013-03-08 | Use of obestatin for muscle regeneration |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201230367A ES2425448B8 (es) | 2012-03-12 | 2012-03-12 | Uso de la obestatina para la regeneración muscular |
Publications (3)
Publication Number | Publication Date |
---|---|
ES2425448A1 ES2425448A1 (es) | 2013-10-15 |
ES2425448B2 ES2425448B2 (es) | 2014-11-07 |
ES2425448B8 true ES2425448B8 (es) | 2015-03-17 |
Family
ID=49160293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES201230367A Expired - Fee Related ES2425448B8 (es) | 2012-03-12 | 2012-03-12 | Uso de la obestatina para la regeneración muscular |
Country Status (4)
Country | Link |
---|---|
US (1) | US20150094264A1 (es) |
EP (1) | EP2862577B1 (es) |
ES (1) | ES2425448B8 (es) |
WO (1) | WO2013135928A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020058533A1 (en) * | 2018-09-21 | 2020-03-26 | Universidade De Santiago De Compostela | Obestatin for use in the treatment of peripheral nerve damages or injuries |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001087933A2 (en) * | 2000-05-11 | 2001-11-22 | Zymogenetics, Inc. | Zsig33-like peptides |
US20060229250A1 (en) * | 2005-03-09 | 2006-10-12 | Jian Zhang | Ghrelin associated peptide and its uses |
US20100323950A1 (en) * | 2007-09-11 | 2010-12-23 | Dorian Bevec | Use of beta-melanotropin as a therapeutic agent, eg for the treatment of aids or alzheimer |
WO2009033714A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
EP2350118B1 (en) * | 2008-09-19 | 2016-03-30 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
-
2012
- 2012-03-12 ES ES201230367A patent/ES2425448B8/es not_active Expired - Fee Related
-
2013
- 2013-03-08 US US14/384,766 patent/US20150094264A1/en not_active Abandoned
- 2013-03-08 EP EP13761384.0A patent/EP2862577B1/en not_active Not-in-force
- 2013-03-08 WO PCT/ES2013/070149 patent/WO2013135928A1/es active Application Filing
Also Published As
Publication number | Publication date |
---|---|
EP2862577A4 (en) | 2015-11-11 |
EP2862577B1 (en) | 2017-08-02 |
EP2862577A1 (en) | 2015-04-22 |
ES2425448B2 (es) | 2014-11-07 |
US20150094264A1 (en) | 2015-04-02 |
WO2013135928A1 (es) | 2013-09-19 |
ES2425448A1 (es) | 2013-10-15 |
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Legal Events
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FG2A | Definitive protection |
Ref document number: 2425448 Country of ref document: ES Kind code of ref document: B2 Effective date: 20141107 |
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