JP2010516304A - 超音波と光学を複合した画像手段を有する撮像プローブ - Google Patents
超音波と光学を複合した画像手段を有する撮像プローブ Download PDFInfo
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Abstract
【選択図】図5
Description
本件特許出願は、2007年1月19日提出の米国暫定特許出願整理番号60/881,169、名称「IMAGING PROBE」に関連し、その優先権の利益を主張するものであって、これは全体として参照により本書に組み込まれる。
Yock(米国特許番号4,794,931)には、血管内超音波用のカテーテルシステムが開示され、血管構造の高解像度撮像を提供している。このシステムは外側シースを具え、その内部には長いトルクケーブルの遠位端部の近傍に超音波トランスデューサがある。モータがトルクケーブルと超音波トランスデューサを回転させると、血管の解剖学的構造の2D断面図が形成される。カテーテルまたはトルクケーブルと超音波トランスデューサの線形移動と、超音波トランスデューサの回転動作の組み合わせにより、カテーテルの長さに沿った一連の2D画像の取得が可能となる。
a)細長い中空のシャフトであって、遠位と近位の端部と細長い中間部とを有する長軸と、前記細長い中空シャフト内に前記近位端部から離れて配置された撮像アセンブリとを具え、前記撮像アセンブリは撮像導管の第1の端部に接続され、前記撮像導管は前記細長い中空シャフトを通って延在し、その第2の端部から前記近位端部を通って画像処理・表示システムに接続され、前記撮像導管は遠位端部を有する光ファイバを具え、前記撮像アセンブリが、前記光ファイバの遠位端部に接続され前記光ファイバの遠位端部の外部に光撮像エネルギを放射し反射した光撮像エネルギ信号を受信し当該受信した反射光撮像エネルギ信号を前記画像処理・表示システムに送る光配向・受光手段を具える光学エミッタ/コレクタを具え、前記撮像アセンブリは超音波トランスデューサを具え、当該超音波トランスデューサは超音波撮像エネルギを照射および受信し、前記撮像導管は前記超音波トランスデューサを超音波信号生成器および前記画像処理・表示システムに電気的に接続する導電体を具え;
b)前記撮像アセンブリは、前記光を前記光学エミッタ/コレクタから、超音波を前記超音波トランスデューサから、前記細長い中空シャフト以外の経路に沿って供給するよう構成されたスキャン機構を具え、前記超音波トランスデューサと光学エミッタ/コレクタは、対象領域のスキャンにおいて超音波画像と工学画像を正確に同時記録できるように互いに配置および配向されており;
c)前記撮像導管と前記撮像アセンブリに動きを伝達する駆動機構と;
d)前記駆動機構と前記画像処理・表示システムとに接続され、前記対象領域のスキャンにおいて超音波撮像および光学撮像で取得された画像を処理し、前記超音波画像と光学画像を同時記録するよう構成されたコントローラと;
e)前記同時記録した画像を表示する表示手段とを具える。
Claims (27)
- 体内の管腔や窩洞に挿入して、当該体内の管腔や窩洞の内部を撮像するか体の外側を撮像する撮像プローブにおいて、
a)細長い中空のシャフトであって、遠位と近位の端部と細長い中間部とを有する長軸と、前記細長い中空シャフト内に前記近位端部から離れて配置された撮像アセンブリとを具え、前記撮像アセンブリは撮像導管の第1の端部に接続され、前記撮像導管は前記細長い中空シャフトを通って延在し、その第2の端部から前記近位端部を通って画像処理・表示システムに接続され、前記撮像導管は遠位端部を有する光ファイバを具え、前記撮像アセンブリが、前記光ファイバの遠位端部に接続され前記光ファイバの遠位端部の外部に光撮像エネルギを放射し反射した光撮像エネルギ信号を受信し当該受信した反射光撮像エネルギ信号を前記画像処理・表示システムに送る光配向・受光手段を具える光学エミッタ/コレクタを具え、前記撮像アセンブリは超音波トランスデューサを具え、当該超音波トランスデューサは超音波撮像エネルギを照射および受信し、前記撮像導管は前記超音波トランスデューサを超音波信号生成器および前記画像処理・表示システムに電気的に接続する導電体を具え;
b)前記撮像アセンブリは、前記光を前記光学エミッタ/コレクタから、超音波を前記超音波トランスデューサから、前記細長い中空シャフト以外の経路に沿って供給するよう構成されたスキャン機構を具え、前記超音波トランスデューサと光学エミッタ/コレクタは、対象領域のスキャンにおいて超音波画像と工学画像を正確に同時記録できるように互いに配置および配向されており;
c)前記撮像導管と前記撮像アセンブリに動きを伝達する駆動機構と;
d)前記駆動機構と前記画像処理・表示システムとに接続され、前記対象領域のスキャンにおいて超音波撮像および光学撮像で取得された画像を処理し、前記超音波画像と光学画像を同時記録するよう構成されたコントローラと;
e)前記同時記録した画像を表示する表示手段とを具えることを特徴とする撮像プローブ。 - 請求項1の撮像プローブにおいて、前記動きを伝達する駆動機構は、前記長軸周りに回転動作を伝達する回転駆動機構であることを特徴とする撮像プローブ。
- 請求項2の撮像プローブにおいて、前記回転動作はある角速度で生じ、前記角速度は前記回転駆動機構用の調整手段によって調整されることを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記動きは前記細長い中空シャフト内での前記撮像アセンブリの前後並進動作であることを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記光学エミッタ/コレクタと前記超音波トランスデューサは、前記超音波撮像エネルギと光学撮像エネルギがほぼ同じ方向のほぼ同じ伝搬経路に沿って受け取られるように互いに対して位置づけられ配向されることを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記光学エミッタ/コレクタと前記超音波トランスデューサは、撮像エネルギの第1のビームによるスキャン経路が選択された撮像エネルギの第2のビームにより優勢な方法で追従され、前記第1の撮像ビームはi)光撮像エネルギのビームと、ii)超音波撮像エネルギのビームの組から選択され、前記撮像エネルギの第2のビームは前記組から第1の撮像ビームとして選択されなかった撮像ビームであり、前記優勢な方法とはある開始時点から始まる期間内における前記第2の撮像ビームの軸それ自体が前記開始時点における前記第1の撮像ビームの軸より先の位置から外れないことを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記光学エミッタ/コレクタは、前記光ファイバの遠位端部から前記撮像される関心領域へと照射される光を収束してそこから反射される光を集光する収束・集光部品を具えることを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記光学エミッタ/コレクタは、前記超音波トランスデューサに組み込まれていることを特徴とする撮像プローブ。
- 請求項8の撮像プローブにおいて、前記超音波トランスデューサは、これを通して前記超音波が放射される表面領域を具え、前記超音波トランスデューサは、内部に設けられた光透過チャネルを具え、前記光学エミッタ/コレクタは、前記光透過チャネル内に配置されて前記光透過チャネルを通して光を放出し、これにより前記放射された超音波信号と前記放射された光が前記関心領域を同時にスキャンすることを特徴とする撮像プローブ。
- 請求項8の撮像プローブにおいて、前記超音波トランスデューサは、これを通して超音波信号が放射される表面領域を具え、前記光学エミッタ/コレクタは、前記超音波信号が放射される方向に対して予め選択された角度で光を放射するように前記超音波トランスデューサに対し搭載されており、これにより前記放射された超音波信号と前記放射された光が前記関心領域を異なる時間にスキャンすることを特徴とする撮像プローブ。
- 請求項10の撮像プローブにおいて、前記予め選択された角度は、90度、35度、または180度の組から選択されることを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記光学エミッタ/コレクタは第1の光学エミッタ/コレクタであるとともに、前記第1の光学エミッタ/コレクタに対し予め選択された角度で光を放射するよう構成された第2の光学エミッタ/コレクタを少なくとも具え、これにより前記第1の光学エミッタ/コレクタから放射される光と前記第2の光学エミッタ/コレクタから放射される光が前記関心領域を異なる時間にスキャンすることを特徴とする撮像プローブ。
- 請求項12の撮像プローブにおいて、前記第1と前記少なくとも第2の光学エミッタ/コレクタが、前記超音波トランスデューサに組み込まれていることを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記光学エミッタ/コレクタと前記超音波トランスデューサは同じ関心領域を同時にスキャンする概略同じ方向に放射すべく同軸上に配列されるとともに、前記スキャン機構は前記光学エミッタ/コレクタからの前記光と前記超音波トランスデューサからの超音波を反射するよう搭載された反射部材を具えることを特徴とする撮像プローブ。
- 請求項14の撮像プローブにおいて、前記反射部材は可動式の反射部材であり、前記可動式反射部材は、前記予め選択された角速度の作用で角度が変更できるように取り付けられていることを特徴とする撮像プローブ。
- 請求項15の撮像プローブにおいて、前記反射部材が音響反射層と光学反射層とを具え、前記音響反射層と前記光学反射層は異なる層であることを特徴とする撮像プローブ。
- 請求項16の撮像プローブにおいて、前記音響反射層は、前記超音波撮像エネルギを収束するよう形成されていることを特徴とする撮像プローブ。
- 請求項15の撮像プローブにおいて、前記可動式反射部材は前記撮像アセンブリに回動可能に搭載され、回動軸が前記長軸と直交することを特徴とする撮像プローブ。
- 請求項1の撮像プローブにおいて、前記スキャン機構が、前記光学エミッタ/コレクタと前記超音波トランスデューサが取り付けられる可動部材を具え、前記可動部材は前記角速度の作用で角度が変更できるように取り付けられていることを特徴とする撮像プローブ。
- 請求項19の撮像プローブにおいて、前記可動部材はその回動軸が前記長軸に直交するように回動可能に搭載されており、動作時に前記撮像アセンブリが回転すると、前記可動部材が求心加速度の結果として前記回動軸周りで傾き、その傾きの量は前記撮像アセンブリの角速度により決定され、これにより前記光と超音波エネルギが前記撮像アセンブリから放射される前記長軸に対する角度が決定することを特徴とする撮像プローブ。
- 請求項19または20の撮像プローブにおいて、前記光学エミッタ/コレクタと超音波トランスデューサは、同じ関心領域を同時にスキャンする概略同じ方向に放射すべく同軸上に配列されることを特徴とする撮像プローブ。
- 請求項19の撮像プローブにおいて、前記可動部材は、前記撮像アセンブリの長軸からの半径方向の距離に対する長さに沿った1またはそれ以上の地点で圧迫された構造体アセンブリを含む可撓性部材であるが、その長さの殆どの部分で圧迫されておらず、前記光学エミッタ/コレクタと前記超音波トランスデューサは前記可撓性部材の圧迫されていない部分に搭載され、動作時に前記撮像アセンブリが回転すると、前記可撓性部材が求心加速度の結果として撓み、この可撓性部材が撓む量は前記撮像アセンブリの角速度により決定され、これにより前記光と超音波エネルギが前記撮像アセンブリから放射される前記長軸に対する角度が決定することを特徴とする撮像プローブ。
- 請求項1乃至22のいずれか1項の撮像プローブにおいて、前記光学撮像エネルギは、光学干渉断層撮影法による撮像を実現すべく用いられることを特徴とする撮像プローブ。
- 請求項1乃至22のいずれか1項の撮像プローブにおいて、前記光学撮像エネルギは可視光であることを特徴とする撮像プローブ。
- 請求項1乃至22のいずれか1項の撮像プローブにおいて、前記光学撮像エネルギは赤外線光であることを特徴とする撮像プローブ。
- 請求項1乃至25のいずれか1項の撮像プローブにおいて、前記撮像アセンブリと前記コントローラに接続された回転エンコーダ機構を具え、前記撮像アセンブリの回転動作は前記回転エンコーダにより検出され、前記画像処理・表示システムは前記検出された回転動作を用いて撮像角度を推断するよう構成されていることを特徴とする撮像プローブ。
- 請求項1乃至26のいずれか1項の撮像プローブにおいて、前記体内管腔または窩洞には、人工的手段により製造されたものも含むことを特徴とする撮像プローブ。
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