JP6538956B2 - 超音波と光学を複合した画像手段を有する撮像プローブ - Google Patents
超音波と光学を複合した画像手段を有する撮像プローブ Download PDFInfo
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- A61B5/0035—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
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- A61B1/05—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
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- G10K11/00—Methods or devices for transmitting, conducting or directing sound in general; Methods or devices for protecting against, or for damping, noise or other acoustic waves in general
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Description
本件特許出願は、2007年1月19日提出の米国暫定特許出願整理番号60/881,169、名称「IMAGING PROBE」に関連し、その優先権の利益を主張するものであって、これは全体として参照により本書に組み込まれる。
Yock(米国特許番号4,794,931)には、血管内超音波用のカテーテルシステムが開示され、血管構造の高解像度撮像を提供している。このシステムは外側シースを具え、その内部には長いトルクケーブルの遠位端部の近傍に超音波トランスデューサがある。モータがトルクケーブルと超音波トランスデューサを回転させると、血管の解剖学的構造の2D断面図が形成される。カテーテルまたはトルクケーブルと超音波トランスデューサの線形移動と、超音波トランスデューサの回転動作の組み合わせにより、カテーテルの長さに沿った一連の2D画像の取得が可能となる。
a)細長い中空のシャフトであって、遠位と近位の端部と細長い中間部とを有する長軸と、前記細長い中空シャフト内に前記近位端部から離れて配置された撮像アセンブリとを具え、前記撮像アセンブリは撮像導管の第1の端部に接続され、前記撮像導管は前記細長い中空シャフトを通って延在し、その第2の端部から前記近位端部を通って画像処理・表示システムに接続され、前記撮像導管は遠位端部を有する光ファイバを具え、前記撮像アセンブリが、前記光ファイバの遠位端部に接続され前記光ファイバの遠位端部の外部に光撮像エネルギを放射し反射した光撮像エネルギ信号を受信し当該受信した反射光撮像エネルギ信号を前記画像処理・表示システムに送る光配向・受光手段を具える光学エミッタ/コレクタを具え、前記撮像アセンブリは超音波トランスデューサを具え、当該超音波トランスデューサは超音波撮像エネルギを照射および受信し、前記撮像導管は前記超音波トランスデューサを超音波信号生成器および前記画像処理・表示システムに電気的に接続する導電体を具え;
b)前記撮像アセンブリは、前記光を前記光学エミッタ/コレクタから、超音波を前記超音波トランスデューサから、前記細長い中空シャフト以外の経路に沿って供給するよう構成されたスキャン機構を具え、前記超音波トランスデューサと光学エミッタ/コレクタは、対象領域のスキャンにおいて超音波画像と工学画像を正確に同時記録できるように互いに配置および配向されており;
c)前記撮像導管と前記撮像アセンブリに動きを伝達する駆動機構と;
d)前記駆動機構と前記画像処理・表示システムとに接続され、前記対象領域のスキャンにおいて超音波撮像および光学撮像で取得された画像を処理し、前記超音波画像と光学画像を同時記録するよう構成されたコントローラと;
e)前記同時記録した画像を表示する表示手段とを具える。
Claims (17)
- 撮像プローブを制御し当該撮像プローブから収集される撮像データに基づいて画像を生成する方法において、前記撮像プローブが2又はそれ以上の撮像様式にしたがって画像を取得するよう構成され、当該方法が、
前記撮像プローブが、第1の撮像様式にしたがって第1の画像を取得し、第2の撮像様式にしたがって第2の画像を取得するように、前記撮像プローブに制御信号を送信するステップであって、前記撮像プローブが、それぞれが前記第1の撮像様式及び前記第2の撮像様式に関連する第1及び第2の撮像手段を具える撮像アセンブリを具え、前記第1の撮像様式が光学干渉断層撮影法であり、前記第2の撮像様式が血管内超音波法であり、前記第1の画像及び第2の画像が前記第1の撮像手段及び前記第2の撮像手段の相対的整合の結果として空間的に同時記録されるように、前記第1の撮像手段及び前記第2の撮像手段が整合して共通の領域内にそれぞれの撮像ビームを向ける、ステップと、
前記撮像プローブから、前記第1及び第2の画像にそれぞれ関連する光学干渉断層撮像データ及び血管内超音波撮像データを受信するステップと、
複合画像を生成及び表示するステップと、
を具え、前記複合画像が、
前記血管の管腔境界を特定する単一管腔境界輪郭であって、前記血管内超音波撮像データを処理することなく前記光学干渉断層撮像データを処理することによって生成される単一管腔境界輪郭と、
前記血管の外側境界を特定する単一外側境界輪郭であって、前記光学干渉断層撮像データを処理しないで前記血管内超音波撮像データを処理することによって生成される単一外側境界輪郭と、
を具えることを特徴とする方法。 - 請求項1に記載の方法において、前記管腔境界及び前記外側境界を特定するステップが、半自動識別によって実施されることを特徴とする方法。
- 請求項2に記載の方法において、
前記管腔境界及び前記外側境界の前記半自動識別が、ユーザから、画像処理アルゴリズムための開始点又は画像処理アルゴリズムによって生成された結果のリファインを受け取ることを具えることを特徴とする方法。 - 請求項1〜3のいずれか一項に記載の方法において、
さらなる画像が、前記血管内超音波撮像データ及び前記光学干渉断層撮像データのうちの一方からの撮像データを具えることを特徴とする方法。 - 請求項1〜3のいずれか一項に記載の方法において、
さらなる画像が、前記血管内超音波撮像データ及び前記光学干渉断層撮像データの双方からの撮像データを具えることを特徴とする方法。 - 請求項1に記載の方法において、
さらなる画像が組織のタイプのカラーマップを具えており、前記カラーマップが、パターン認識システムで前記血管内超音波撮像データ及び前記光学干渉断層撮像データを処理することによって生成されることを特徴とする方法。 - 請求項1に記載の方法において、
前記光学干渉断層撮像データを処理するステップ及び前記血管内超音波撮像データを処理するステップの一方又は双方が、パターン認識アルゴリズムを実行することを具えることを特徴とする方法。 - 請求項1に記載の方法において、
前記光学干渉断層撮像データを処理するステップ及び前記血管内超音波撮像データを処理するステップの一方又は双方が、1又はそれ以上の組織のタイプを特定することを具えることを特徴とする方法。 - 請求項1に記載の方法において、
さらに、前記光学干渉断層撮像データを処理して、光学干渉断層の減衰及び光学干渉断層の偏光感度の1又はそれ以上にしたがって特性を特定するステップを具えることを特徴とする方法。 - 請求項1に記載の方法において、
さらに、前記光学干渉断層撮像データを処理して、分光情報に基づいて特性を特定するステップを具えることを特徴とする方法。 - 請求項1に記載の方法において、前記管腔境界が、エッジ検出アルゴリズムにしたがって特定されることを特徴とする方法。
- 請求項1に記載の方法において、さらに、
前記管腔境界と前記血管の外側境界との間に延在する領域内の2又はそれ以上の撮像様式からの撮像データを処理して、前記血管の血管壁内の1又はそれ以上の組織要素を評価するステップを具えており、
さらなる画像が、前記血管壁内の評価された組織要素に基づいて生成されるカラーマップを具えることを特徴とする方法。 - 請求項12に記載の方法において、
前記1又はそれ以上の組織要素が、石灰化、繊維質、アテローム、血栓症、金属、および無病の領域から成る群から選択されることを特徴とする方法。 - 請求項1に記載の方法において、さらに、
前記管腔境界と前記血管の外側境界との間にある関心のある領域内の2又はそれ以上の撮像様式からの撮像データを処理して、構成の評価を形成するステップを具えることを特徴とする方法。 - 請求項1に記載の方法において、さらに、
前記第2の画像のデータを処理して、シャドーイングに関する特性を特定するステップを具えることを特徴とする方法。 - 請求項1に記載の方法において、さらに、
前記光学干渉断層撮像データを処理して、前記光学干渉断層撮像データの減衰に基づいて繊維キャップを特定するステップを具えることを特徴とする方法。 - 請求項1に記載の方法において、さらに、
前記光学干渉断層撮像データを処理して、前記光学干渉断層撮像データの偏光感度に基づいて繊維キャップを特定するステップを具えることを特徴とする方法。
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Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88116907P | 2007-01-19 | 2007-01-19 | |
US60/881,169 | 2007-01-19 |
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