|
US7048906B2
(en)
|
1995-05-17 |
2006-05-23 |
Cedars-Sinai Medical Center |
Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
|
|
EP1950223A3
(en)
|
1998-03-09 |
2009-05-13 |
Zealand Pharma A/S |
Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
|
|
SE9801571D0
(sv)
|
1998-05-05 |
1998-05-05 |
Wapharm Ab |
Melanokortin-1-receptorselektiva föreningar
|
|
US6444788B1
(en)
|
1999-03-15 |
2002-09-03 |
Novo Nordisk A/S |
Ion exchange chromatography of GLP-1, analogs and derivatives thereof
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
US7371721B2
(en)
|
2000-09-18 |
2008-05-13 |
Sanos Bioscience A/S |
Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
|
|
DE60134251D1
(de)
|
2000-09-18 |
2008-07-10 |
Sanos Bioscience As |
Verwendung von glp-2-peptiden
|
|
WO2002047716A2
(en)
*
|
2000-12-13 |
2002-06-20 |
Eli Lilly And Company |
Chronic treatment regimen using glucagon-like insulinotropic peptides
|
|
CN1162446C
(zh)
*
|
2001-05-10 |
2004-08-18 |
上海华谊生物技术有限公司 |
促胰岛素分泌肽衍生物
|
|
CN1158304C
(zh)
*
|
2001-05-10 |
2004-07-21 |
上海华谊生物技术有限公司 |
蛙皮抗菌肽衍生物
|
|
JP5562510B2
(ja)
|
2001-06-28 |
2014-07-30 |
ノヴォ ノルディスク アー/エス |
修飾glp−1の安定な処方剤
|
|
CA2455963C
(en)
*
|
2001-07-31 |
2017-07-04 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Glp-1, exendin-4, peptide analogs and uses thereof
|
|
US7176278B2
(en)
|
2001-08-30 |
2007-02-13 |
Biorexis Technology, Inc. |
Modified transferrin fusion proteins
|
|
US8129504B2
(en)
|
2001-08-30 |
2012-03-06 |
Biorexis Technology, Inc. |
Oral delivery of modified transferrin fusion proteins
|
|
IL160983A0
(en)
|
2001-09-24 |
2004-08-31 |
Imp College Innovations Ltd |
Use of pyy for preparation of a medicament for modification of feeding behavior
|
|
EP1461069A2
(en)
|
2001-12-29 |
2004-09-29 |
Novo Nordisk A/S |
Combined use of a glp-1 compound and another drug for treating dyslipidemia
|
|
EP1474163A2
(en)
|
2002-01-10 |
2004-11-10 |
Imperial College Innovations Limited |
Modification of feeding behavior
|
|
US7105489B2
(en)
*
|
2002-01-22 |
2006-09-12 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for treating polycystic ovary syndrome
|
|
AU2003226913A1
(en)
*
|
2002-04-04 |
2003-10-20 |
Novo Nordisk A/S |
Glp-1 agonist and cardiovascular complications
|
|
DE60327771D1
(de)
*
|
2002-07-04 |
2009-07-09 |
Zealand Pharma As |
Glp-1 und behandlungsmethode für diabetes
|
|
EP1539210A4
(en)
*
|
2002-09-06 |
2006-06-07 |
Bayer Pharmaceuticals Corp |
GLP-1 RECEPTOR MODIFIED AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE
|
|
US7273921B2
(en)
|
2002-09-25 |
2007-09-25 |
Novo Nordisk A/S |
Method for producing acylated peptides
|
|
US7544657B2
(en)
|
2002-10-02 |
2009-06-09 |
Zealand Pharma A/S |
Stabilized Exendin-4 compounds
|
|
CN100354306C
(zh)
*
|
2002-10-11 |
2007-12-12 |
株式会社三和化学研究所 |
Glp-1衍生物及其经粘膜吸收的制剂
|
|
US6818721B2
(en)
|
2002-12-02 |
2004-11-16 |
Rpo Pty Ltd. |
Process for producing polysiloxanes and use of the same
|
|
EP1688148A1
(en)
*
|
2002-12-03 |
2006-08-09 |
Novo Nordisk A/S |
Combination treatment using exendin-4 and thiazolidinediones
|
|
AU2003283216A1
(en)
*
|
2002-12-03 |
2004-06-23 |
Novo Nordisk A/S |
Combination treatment using exendin-4 and thiazolidinediones
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
EP1626981A4
(en)
*
|
2003-03-04 |
2006-11-22 |
Biorexis Pharmaceutical Corp |
PROTEINS PROTECTED AGAINST DIPEPTIDYLPEPTIDASE
|
|
DE10314610A1
(de)
|
2003-04-01 |
2004-11-04 |
Aventis Pharma Deutschland Gmbh |
Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
|
|
EP1631308B1
(en)
|
2003-05-30 |
2013-07-31 |
Amylin Pharmaceuticals, LLC |
Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins
|
|
US7008957B2
(en)
|
2003-07-25 |
2006-03-07 |
Sanofi-Aventis Deutschland Gmbh |
Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments
|
|
US7094800B2
(en)
|
2003-07-25 |
2006-08-22 |
Sanofi-Aventis Deutschland Gmbh |
Cyanopyrrolidides, process for their preparation and their use as medicaments
|
|
US7094794B2
(en)
|
2003-07-28 |
2006-08-22 |
Sanofi-Aventis Deutschland Gmbh |
Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use
|
|
DE10335092B3
(de)
|
2003-08-01 |
2005-02-03 |
Aventis Pharma Deutschland Gmbh |
Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
|
|
RU2401276C2
(ru)
*
|
2003-09-19 |
2010-10-10 |
Ново Нордиск А/С |
Производные глюкагон-подобного пептида-1 (glp-1)
|
|
EP1670515A2
(en)
*
|
2003-09-19 |
2006-06-21 |
Novo Nordisk A/S |
Albumin-binding derivatives of therapeutic peptides
|
|
TW200522976A
(en)
|
2003-09-19 |
2005-07-16 |
Novo Nordisk As |
Novel plasma protein affinity tags
|
|
CN100444898C
(zh)
*
|
2003-09-19 |
2008-12-24 |
诺沃挪第克公司 |
治疗肽的清蛋白结合型衍生物
|
|
JP4800959B2
(ja)
*
|
2003-11-13 |
2011-10-26 |
ノヴォ ノルディスク アー/エス |
糖尿病及び過食症を治療するためのglp−1ペプチド及び短時間作用型インスリンペプチドを含む、非経口投与用の可溶性医薬組成物
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
SI1687019T1
(en)
|
2003-11-20 |
2018-04-30 |
Novo Nordisk A/S |
Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices
|
|
WO2005056036A2
(en)
|
2003-12-09 |
2005-06-23 |
Novo Nordisk A/S |
Regulation of food preference using glp-1 agonists
|
|
US20080015144A1
(en)
*
|
2003-12-12 |
2008-01-17 |
Alvert Einstein College Of Medicine Of Yeshiva Uni |
Glp- (9-36) Methods and Compositions
|
|
MXPA06006745A
(es)
|
2003-12-18 |
2006-08-18 |
Novo Nordisk As |
Compuestos glp-1 novedosos.
|
|
EP2422807A3
(en)
|
2004-02-11 |
2012-05-30 |
Amylin Pharmaceuticals Inc. |
Hybrid polypeptides with selectable properties
|
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
|
CN1318587C
(zh)
*
|
2004-04-30 |
2007-05-30 |
成都芝田生物工程有限公司 |
酰胺化Exendin-4多肽的重组制备方法
|
|
WO2005120492A1
(en)
|
2004-06-11 |
2005-12-22 |
Novo Nordisk A/S |
Counteracting drug-induced obesity using glp-1 agonists
|
|
DE102004043153B4
(de)
*
|
2004-09-03 |
2013-11-21 |
Philipps-Universität Marburg |
Erfindung betreffend GLP-1 und Exendin
|
|
AU2012202855B2
(en)
*
|
2004-09-03 |
2015-02-26 |
Philipps-Universitat Marburg |
GLP-1 and exendin related invention
|
|
WO2006037810A2
(en)
|
2004-10-07 |
2006-04-13 |
Novo Nordisk A/S |
Protracted glp-1 compounds
|
|
EP1799711B1
(en)
*
|
2004-10-07 |
2012-06-20 |
Novo Nordisk A/S |
Protracted exendin-4 compounds
|
|
WO2006051103A2
(en)
*
|
2004-11-12 |
2006-05-18 |
Novo Nordisk A/S |
Stable formulations of peptides
|
|
DE102004058306A1
(de)
*
|
2004-12-01 |
2006-07-27 |
Sanofi-Aventis Deutschland Gmbh |
Verfahren zur Herstellung von Carboxy-terminal amidierten Peptiden
|
|
US8716221B2
(en)
|
2005-01-14 |
2014-05-06 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
|
CA2603630C
(en)
*
|
2005-01-14 |
2015-06-09 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
|
SG159551A1
(en)
|
2005-02-11 |
2010-03-30 |
Amylin Pharmaceuticals Inc |
Gip analog and hybrid polypeptides with selectable properties
|
|
WO2006096565A2
(en)
*
|
2005-03-04 |
2006-09-14 |
Curedm Inc. |
Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions
|
|
EP1863521B1
(en)
*
|
2005-03-18 |
2014-05-07 |
Novo Nordisk A/S |
Extended glp-1 compounds
|
|
TWI362392B
(en)
*
|
2005-03-18 |
2012-04-21 |
Novo Nordisk As |
Acylated glp-1 compounds
|
|
WO2006097535A2
(en)
*
|
2005-03-18 |
2006-09-21 |
Novo Nordisk A/S |
Peptide agonists of the glucagon family with secretin like activity
|
|
EP2295452A1
(en)
|
2005-05-04 |
2011-03-16 |
Zealand Pharma A/S |
Glucagon-like-peptide-2 (GLP-2) analogues
|
|
CA2609667C
(en)
|
2005-05-25 |
2011-02-22 |
Curedm, Inc. |
Human proislet peptide, derivatives and analogs thereof, and methods of using same
|
|
CA2617649A1
(en)
|
2005-08-11 |
2007-02-22 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
|
EP2330125A3
(en)
|
2005-08-11 |
2012-12-12 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
|
NZ566489A
(en)
|
2005-08-26 |
2008-10-31 |
Action Pharma As |
Therapeutically active alpha-MSH analogues
|
|
DE102006031962A1
(de)
|
2006-07-11 |
2008-01-17 |
Sanofi-Aventis Deutschland Gmbh |
Amidiertes Insulin Glargin
|
|
DE102006031955A1
(de)
|
2006-07-11 |
2008-01-17 |
Sanofi-Aventis Deutschland Gmbh |
Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
|
|
CA2658654A1
(en)
|
2006-07-24 |
2008-01-31 |
Biorexis Pharmaceutical Corporation |
Exendin fusion proteins
|
|
RU2009108280A
(ru)
|
2006-08-08 |
2010-09-20 |
Санофи-Авентис (Fr) |
Ариламиноарилалкилзамещенные имидазолидин-2,4-дионы, способы их получения, содержащие эти соединения лекарственные средства и их применение
|
|
CA2662084A1
(en)
|
2006-09-07 |
2008-03-13 |
Nycomed Gmbh |
Combination treatment for diabetes mellitus
|
|
US8642727B2
(en)
|
2006-11-08 |
2014-02-04 |
Zealand Pharma A/S |
Selective glucagon-like-peptide-2 (GLP-2) analogues
|
|
JP2010043001A
(ja)
*
|
2006-11-09 |
2010-02-25 |
Sanwa Kagaku Kenkyusho Co Ltd |
Glp−1誘導体とその用途
|
|
US8785400B2
(en)
|
2006-11-22 |
2014-07-22 |
Curedm Group Holdings, Llc |
Methods and compositions relating to islet cell neogenesis
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
RU2413528C2
(ru)
|
2007-01-18 |
2011-03-10 |
Открытое Акционерное Общество "Валента Фармацевтика" |
Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
|
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2008098693A2
(en)
*
|
2007-02-16 |
2008-08-21 |
Bayer Healthcare Ag |
Convergent synthesis of glp-1
|
|
CA2963857A1
(en)
|
2007-06-04 |
2008-12-11 |
Ben-Gurion University Of The Negev Research And Development Authority |
Tri-aryl compounds and compositions comprising the same
|
|
US7994122B2
(en)
|
2007-06-15 |
2011-08-09 |
Zealand Pharma A/S |
Glucagon analogues
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
EP2570431A3
(en)
|
2007-08-30 |
2013-05-01 |
CureDM Group Holdings, LLC |
Compositions and methods of using proislet peptides and analogs thereof
|
|
EP2190872B1
(en)
|
2007-09-05 |
2018-03-14 |
Novo Nordisk A/S |
Glucagon-like peptide-1 derivatives and their pharmaceutical use
|
|
CN101842386A
(zh)
|
2007-09-05 |
2010-09-22 |
诺沃-诺迪斯克有限公司 |
截短的glp-1衍生物和它们的治疗用途
|
|
CN101835794A
(zh)
|
2007-10-27 |
2010-09-15 |
霍夫曼-拉罗奇有限公司 |
使用固相和溶液相组合技术的促胰岛素肽合成法
|
|
DE102007054497B3
(de)
|
2007-11-13 |
2009-07-23 |
Sanofi-Aventis Deutschland Gmbh |
Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
|
|
WO2009063072A2
(en)
|
2007-11-16 |
2009-05-22 |
Novo Nordisk A/S |
Pharmaceutical compositions containing insulin and an insulinotropic peptide
|
|
BRPI0907119A2
(pt)
|
2008-01-09 |
2015-07-14 |
Sanofi Aventis Deutschland |
Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
|
|
DK2229407T3
(en)
|
2008-01-09 |
2017-02-27 |
Sanofi Aventis Deutschland |
NEW INSULIN DERIVATIVES WITH EXTREMELY DELAYED TIME / EFFECTS PROFILE
|
|
DE102008003568A1
(de)
|
2008-01-09 |
2009-07-16 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
DE102008025008A1
(de)
|
2008-05-24 |
2009-11-26 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
DE102008003566A1
(de)
|
2008-01-09 |
2009-07-16 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
DE102008025007A1
(de)
|
2008-05-24 |
2009-11-26 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
AU2009274425B2
(en)
*
|
2008-06-17 |
2014-05-15 |
Indiana University Research And Technology Corporation |
GIP-based mixed agonists for treatment of metabolic disorders and obesity
|
|
EP4074327A1
(en)
|
2008-06-27 |
2022-10-19 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
|
EP2310372B1
(en)
|
2008-07-09 |
2012-05-23 |
Sanofi |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
CN102112157B
(zh)
|
2008-08-06 |
2013-05-29 |
诺沃-诺迪斯克保健股份有限公司 |
具有延长的体内效能的缀合蛋白
|
|
CA2740685C
(en)
|
2008-10-17 |
2018-09-11 |
Sanofi-Aventis Deutschland Gmbh |
Combination of an insulin and a glp-1 agonist
|
|
DE102008051834A1
(de)
|
2008-10-17 |
2010-04-22 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102009038210A1
(de)
|
2009-08-20 |
2011-03-03 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102008053048A1
(de)
|
2008-10-24 |
2010-04-29 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DK2344519T3
(en)
|
2008-11-07 |
2017-01-23 |
Massachusetts Gen Hospital |
C-TERMINAL FRAGMENTS OF GLUCAGON SIMILAR PEPTID-1 (GLP-1)
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
WO2010068735A1
(en)
|
2008-12-10 |
2010-06-17 |
Glaxosmithkline Llc. |
Pharmaceutical compositions
|
|
CN102282167B
(zh)
|
2008-12-15 |
2014-08-13 |
西兰制药公司 |
胰高血糖素类似物
|
|
ES2502218T3
(es)
|
2008-12-15 |
2014-10-03 |
Zealand Pharma A/S |
Análogos de glucagón
|
|
CN102282166B
(zh)
|
2008-12-15 |
2015-04-01 |
西兰制药公司 |
胰高血糖素类似物
|
|
WO2010070252A1
(en)
|
2008-12-15 |
2010-06-24 |
Zealand Pharma A/S |
Glucagon analogues
|
|
KR20110122100A
(ko)
|
2009-01-22 |
2011-11-09 |
노보 노르디스크 헬스 케어 악티엔게젤샤프트 |
안정한 성장 호르몬 화합물
|
|
JP5675799B2
(ja)
*
|
2009-07-06 |
2015-02-25 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
遅効性インスリン製剤
|
|
ES2614161T3
(es)
*
|
2009-07-06 |
2017-05-29 |
Sanofi-Aventis Deutschland Gmbh |
Preparados acuosos de insulina que comprenden metionina
|
|
ME02220B
(me)
|
2009-07-13 |
2016-02-20 |
Zealand Pharma As |
Analozi acilovanog glukagona
|
|
CN101987868B
(zh)
*
|
2009-07-30 |
2013-09-04 |
江苏豪森医药集团有限公司 |
Glp-1类似物的衍生物或其可药用盐和用途
|
|
EP2461831B1
(en)
|
2009-08-06 |
2018-11-21 |
Novo Nordisk Health Care AG |
Growth hormones with prolonged in-vivo efficacy
|
|
MX2012001729A
(es)
|
2009-08-26 |
2012-06-13 |
Sanofi Sa |
Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo.
|
|
WO2011048614A2
(en)
|
2009-10-22 |
2011-04-28 |
Cadila Healthcare Limited |
Short chain peptidomimetics based orally active glp-1 agonist and glucagon receptor antagonist
|
|
DE102010011919A1
(de)
|
2010-03-18 |
2011-09-22 |
Sanofi-Aventis Deutschland Gmbh |
Pharmazeutische Zusammensetzung umfassend einen GLP-1-Agonisten und Methionin
|
|
EP3345593B1
(de)
|
2009-11-13 |
2023-09-06 |
Sanofi-Aventis Deutschland GmbH |
Pharmazeutische zusammensetzung umfassend despro36exendin-4(1-39)-lys6-nh2 und methionin
|
|
AU2009238272B2
(en)
*
|
2009-11-13 |
2014-05-08 |
Sanofi-Aventis Deutschland Gmbh |
Method of treatment of diabetes type 2 comprising add-on therapy to metformin
|
|
PT2329848E
(pt)
|
2009-11-13 |
2013-01-23 |
Sanofi Aventis Deutschland |
Lixisenatida como terapia de extensão à insulina glargina e à metformina para tratar a diabetes do tipo
|
|
PL2554183T3
(pl)
|
2009-11-13 |
2018-10-31 |
Sanofi-Aventis Deutschland Gmbh |
Kompozycja farmaceutyczna zawierająca agonistę GLP-1, insulinę i metioninę
|
|
JP2011105609A
(ja)
*
|
2009-11-13 |
2011-06-02 |
Sanofi-Aventis Deutschland Gmbh |
メトホルミンへの付加療法を含む2型糖尿病の治療方法
|
|
PL2324853T3
(pl)
|
2009-11-13 |
2016-01-29 |
Sanofi Aventis Deutschland |
Liksysenatyd jako dodatek do metforminy w leczeniu cukrzycy typu 2
|
|
CN102892425A
(zh)
|
2010-01-20 |
2013-01-23 |
西兰制药公司 |
心脏病症的治疗
|
|
RU2012134974A
(ru)
|
2010-01-22 |
2014-02-27 |
Ново Нордиск Хелс Кеа Аг |
Стабилизированное соединение гормона роста
|
|
CN103002918B
(zh)
|
2010-01-22 |
2016-05-04 |
诺沃—诺迪斯克保健股份有限公司 |
体内功效延长的生长激素
|
|
EP2542565A1
(en)
|
2010-03-01 |
2013-01-09 |
Novo Nordisk A/S |
Preparative rp-hplc method for purifying peptides
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2011123943A1
(en)
|
2010-04-09 |
2011-10-13 |
Mount Sinai Hospital |
Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist
|
|
DE102010015123A1
(de)
|
2010-04-16 |
2011-10-20 |
Sanofi-Aventis Deutschland Gmbh |
Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
TWI523659B
(zh)
|
2010-04-27 |
2016-03-01 |
西蘭製藥公司 |
肽結合物
|
|
EP2566502A4
(en)
|
2010-05-04 |
2013-10-09 |
Glaxosmithkline Llc |
METHODS OF TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND PROVIDING CARDIOVASCULAR PROTECTION
|
|
AU2011202239C1
(en)
|
2010-05-19 |
2017-03-16 |
Sanofi |
Long-acting formulations of insulins
|
|
EP2389945A1
(en)
|
2010-05-28 |
2011-11-30 |
Sanofi-Aventis Deutschland GmbH |
Pharmaceutical composition comprising AVE0010 and insulin glargine
|
|
CN101891823B
(zh)
*
|
2010-06-11 |
2012-10-03 |
北京东方百泰生物科技有限公司 |
一种Exendin-4及其类似物融合蛋白
|
|
US8933024B2
(en)
|
2010-06-18 |
2015-01-13 |
Sanofi |
Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
UY33462A
(es)
|
2010-06-23 |
2012-01-31 |
Zealand Pharma As |
Analogos de glucagon
|
|
KR20130086343A
(ko)
|
2010-06-24 |
2013-08-01 |
질랜드 파마 에이/에스 |
글루카곤 유사체
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
AU2010360116B2
(en)
|
2010-08-30 |
2014-06-26 |
Sanofi-Aventis Deutschland Gmbh |
Use of AVE0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
|
|
WO2012061466A2
(en)
|
2010-11-02 |
2012-05-10 |
The General Hospital Corporation |
Methods for treating steatotic disease
|
|
MX377589B
(es)
|
2010-12-16 |
2025-03-10 |
Novo Nordisk As |
Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico.
|
|
WO2012104342A1
(en)
|
2011-02-02 |
2012-08-09 |
Sanofi-Aventis Deutschland Gmbh |
Prevention of hypoglycaemia in diabetes mellitus type 2 patients
|
|
EP2683698B1
(de)
|
2011-03-08 |
2017-10-04 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8846666B2
(en)
|
2011-03-08 |
2014-09-30 |
Sanofi |
Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
|
EP2683702B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8828994B2
(en)
|
2011-03-08 |
2014-09-09 |
Sanofi |
Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8901114B2
(en)
|
2011-03-08 |
2014-12-02 |
Sanofi |
Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
|
|
US8828995B2
(en)
|
2011-03-08 |
2014-09-09 |
Sanofi |
Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
|
US20120277147A1
(en)
|
2011-03-29 |
2012-11-01 |
Sanofi-Aventis Deutschland Gmbh |
Prevention of hypoglycaemia in diabetes mellitus type 2 patients
|
|
PT2696687T
(pt)
|
2011-04-12 |
2017-02-02 |
Novo Nordisk As |
Derivados de glp-1 duplamente acilados
|
|
US8735349B2
(en)
|
2011-05-13 |
2014-05-27 |
Sanofi-Aventis Deutschland Gmbh |
Method for improving glucose tolerance in a diabetes type 2 patient of younger than 50 years and having postprandial plasma glucose concentration of at least 14 mmol/L
|
|
US20130040878A1
(en)
|
2011-05-13 |
2013-02-14 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for use in the treatment of diabetes type 2 patients
|
|
CN103841988A
(zh)
|
2011-05-13 |
2014-06-04 |
赛诺菲-安万特德国有限公司 |
用于治疗2型糖尿病患者的利西拉来和二甲双胍
|
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
|
EP2729157B1
(en)
|
2011-07-06 |
2019-01-16 |
The General Hospital Corporation |
A pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1) for use in treatment
|
|
WO2013030160A1
(en)
|
2011-08-29 |
2013-03-07 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
|
|
TWI559929B
(en)
|
2011-09-01 |
2016-12-01 |
Sanofi Aventis Deutschland |
Pharmaceutical composition for use in the treatment of a neurodegenerative disease
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013050378A1
(en)
|
2011-10-04 |
2013-04-11 |
Sanofi-Aventis Deutschland Gmbh |
Glp-1 agonist for use in the treatment of stenosis or/and obstruction in the biliary tract
|
|
SI2763690T1
(sl)
|
2011-10-04 |
2016-03-31 |
Sanofi-Aventis Deutschland Gmbh |
Liksisenatid za uporabo pri zdravljenju stenoze in/ali obstrukcije v sistemu vodov trebušne slinavke
|
|
SG11201401175SA
(en)
|
2011-10-28 |
2014-09-26 |
Sanofi Aventis Deutschland |
Treatment protocol of diabetes type 2
|
|
WO2013064669A1
(en)
|
2011-11-03 |
2013-05-10 |
Zealand Pharma A/S |
Glp-1 receptor agonist peptide gastrin conjugates
|
|
CN103087174B
(zh)
*
|
2011-11-03 |
2015-11-18 |
华东师范大学 |
一种glp-1衍生物dlg3312及其固相化学合成方法
|
|
JP2015500823A
(ja)
|
2011-12-09 |
2015-01-08 |
ノヴォ ノルディスク アー/エス |
Glp−1アゴニスト
|
|
CN104144696A
(zh)
|
2011-12-23 |
2014-11-12 |
西兰制药公司 |
胰高血糖素类似物
|
|
LT2827885T
(lt)
|
2012-03-22 |
2018-10-10 |
Novo Nordisk A/S |
Glp-1 peptidų kompozicijos ir jų gavimas
|
|
ES2715308T3
(es)
|
2012-03-22 |
2019-06-03 |
Novo Nordisk As |
Composiciones que comprenden un agente de suministro y su preparación
|
|
CA2872314C
(en)
|
2012-05-03 |
2021-08-31 |
Zealand Pharma A/S |
Gip-glp-1 dual agonist compounds and methods
|
|
AU2013255752B2
(en)
|
2012-05-03 |
2017-11-09 |
Zealand Pharma A/S |
Glucagon-like-peptide-2 (GLP-2) analogues
|
|
EP2863895B1
(en)
|
2012-06-20 |
2021-04-14 |
Novo Nordisk A/S |
Tablet formulation comprising a peptide and a delivery agent
|
|
SG11201500375PA
(en)
|
2012-07-23 |
2015-02-27 |
Zealand Pharma As |
Glucagon analogues
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
US20150297573A1
(en)
|
2012-10-24 |
2015-10-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING Beta-CELL SURVIVAL
|
|
WO2014077575A1
(ko)
*
|
2012-11-13 |
2014-05-22 |
다인바이오 주식회사 |
덱에이 효소반응으로 조제한 항비만 및 항당뇨 효능을 갖는 한천 유래 네오아가로올리고당 복합 조성물
|
|
KR20140088837A
(ko)
*
|
2013-01-03 |
2014-07-11 |
한미약품 주식회사 |
N-말단 전하가 변형된 인슐린 분비 펩티드 유도체
|
|
TWI641381B
(zh)
|
2013-02-04 |
2018-11-21 |
法商賽諾菲公司 |
胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
|
|
JP6457484B2
(ja)
|
2013-04-03 |
2019-01-23 |
サノフイSanofi |
インスリンの長時間作用型製剤による糖尿病の治療
|
|
CN105120887A
(zh)
|
2013-04-05 |
2015-12-02 |
诺和诺德保健股份有限公司 |
生长激素化合物制剂
|
|
HRP20181393T1
(hr)
|
2013-05-02 |
2018-11-02 |
Novo Nordisk A/S |
Oralno doziranje spojeva glp-1
|
|
EP3016975B1
(en)
*
|
2013-07-04 |
2019-01-16 |
Novo Nordisk A/S |
Derivatives of glp-1 like peptides, and uses thereof
|
|
GB201315335D0
(en)
|
2013-08-29 |
2013-10-09 |
Of Singapore |
Amino diacids containing peptide modifiers
|
|
PT3057984T
(pt)
|
2013-10-17 |
2018-10-24 |
Boehringer Ingelheim Int |
Análogos de glucagon acilados
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
KR20160094956A
(ko)
|
2013-11-05 |
2016-08-10 |
벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 |
당뇨병 및 당뇨병으로부터 발생하는 합병증 질환의 치료를 위한 화합물
|
|
CN105849122B
(zh)
|
2013-11-06 |
2021-04-30 |
西兰制药公司 |
Gip-glp-1双重激动剂化合物及方法
|
|
TR201902516T4
(tr)
|
2013-11-06 |
2019-03-21 |
Zealand Pharma As |
Glukagon-glp-1-gıp üçlü agonist bileşikleri.
|
|
CN103613657B
(zh)
*
|
2013-11-28 |
2016-01-13 |
孙玉琨 |
缩短肽链的Exendin4及其基因工程应用
|
|
AU2015205621A1
(en)
|
2014-01-09 |
2016-07-14 |
Sanofi |
Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
US9839692B2
(en)
|
2014-01-09 |
2017-12-12 |
Sanofi |
Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
RU2016132340A
(ru)
|
2014-01-09 |
2018-02-14 |
Санофи |
Стабилизированные фармацевтические составы на основе инсулина аспарта
|
|
KR101768446B1
(ko)
*
|
2014-03-21 |
2017-08-17 |
애니젠 주식회사 |
신규한 엑세나타이드 유사체 및 그의 용도
|
|
EP3212218B1
(en)
|
2014-10-29 |
2021-06-30 |
Zealand Pharma A/S |
Gip agonist compounds and methods
|
|
PE20171622A1
(es)
|
2014-12-12 |
2017-11-02 |
Sanofi Aventis Deutschland |
Formulacion de relacion fija de insulina glargina/lixisenatida
|
|
US20160235818A1
(en)
|
2015-01-16 |
2016-08-18 |
Sanofi-Aventis Deutschland Gmbh |
Treatment of Pediatric Type 2 Diabetes Mellitus Patients
|
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
|
ES2805743T3
(es)
|
2015-03-24 |
2021-02-15 |
Inst Nat Sante Rech Med |
Método y composición farmacéutica para uso en el tratamiento de la diabetes
|
|
ES2763329T3
(es)
|
2015-04-16 |
2020-05-28 |
Zealand Pharma As |
Análogo de glucagón acilado
|
|
AU2017371516C1
(en)
|
2016-12-09 |
2021-09-02 |
Zealand Pharma A/S |
Acylated GLP-1/GLP-2 dual agonists
|
|
TWI791539B
(zh)
|
2017-06-16 |
2023-02-11 |
丹麥商西蘭製藥公司 |
用於投予類升糖素胜肽-2(glp-2)類似物的給藥方案
|
|
FR3082426A1
(fr)
|
2018-06-14 |
2019-12-20 |
Adocia |
Compositions sous forme d'une solution aqueuse injectable comprenant au moins de l'insuline humaine a21g et un suppresseur de glucagon a action prandiale
|
|
BR112020001617A2
(pt)
|
2017-07-27 |
2020-07-21 |
Adocia |
composição sob forma de uma solução aquosa injetável, e, processo de obtenção da insulina humana a21g
|
|
KR102665710B1
(ko)
|
2017-08-24 |
2024-05-14 |
노보 노르디스크 에이/에스 |
Glp-1 조성물 및 그 용도
|
|
KR102647171B1
(ko)
|
2018-02-02 |
2024-03-15 |
노보 노르디스크 에이/에스 |
Glp-1 작용제 및 n-(8-(2-하이드록시벤조일)아미노)카프릴산의 염을 포함하는 고형 조성물
|
|
CA3096493A1
(en)
*
|
2018-04-10 |
2019-10-17 |
Sanofi-Aventis Deutschland Gmbh |
Method for cleavage of solid phase-bound peptides from the solid phase
|
|
JP7332620B2
(ja)
|
2018-04-10 |
2023-08-23 |
サノフィ-アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
キャップ付加を伴うリキシセナチドの合成
|
|
FR3083700B1
(fr)
|
2018-07-13 |
2021-03-12 |
Adocia |
Formulation thermostable d'insuline humaine a21g
|
|
EP3628683A1
(en)
|
2018-09-28 |
2020-04-01 |
Zealand Pharma A/S |
Formulations of glucagon-like-peptide-2 (glp-2) analogues
|
|
EP3628682A1
(en)
|
2018-09-28 |
2020-04-01 |
Zealand Pharma A/S |
Formulations of glucagon-like-peptide-2 (glp-2) analogues
|
|
TWI799680B
(zh)
*
|
2019-01-29 |
2023-04-21 |
美商美國禮來大藥廠 |
製備gip/glp1雙重促效劑之方法
|
|
CN109721653B
(zh)
*
|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
|
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|
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|
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|
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|
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|
|
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|
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