JP2018518485A5 - - Google Patents
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- Publication number
- JP2018518485A5 JP2018518485A5 JP2017563292A JP2017563292A JP2018518485A5 JP 2018518485 A5 JP2018518485 A5 JP 2018518485A5 JP 2017563292 A JP2017563292 A JP 2017563292A JP 2017563292 A JP2017563292 A JP 2017563292A JP 2018518485 A5 JP2018518485 A5 JP 2018518485A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- peg
- pharmaceutical composition
- lipid
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562173631P | 2015-06-10 | 2015-06-10 | |
| US62/173,631 | 2015-06-10 | ||
| US201662343390P | 2016-05-31 | 2016-05-31 | |
| US62/343,390 | 2016-05-31 | ||
| PCT/EP2016/063206 WO2016198544A1 (en) | 2015-06-10 | 2016-06-09 | Protease-resistant lipidated glp-1 analogs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018518485A JP2018518485A (ja) | 2018-07-12 |
| JP2018518485A5 true JP2018518485A5 (enExample) | 2019-05-23 |
| JP6811190B2 JP6811190B2 (ja) | 2021-01-13 |
Family
ID=56235790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563292A Active JP6811190B2 (ja) | 2015-06-10 | 2016-06-09 | プロテアーゼ耐性脂質付加ｇｌｐ−１類似体 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US10414811B2 (enExample) |
| EP (2) | EP3865504A1 (enExample) |
| JP (1) | JP6811190B2 (enExample) |
| KR (1) | KR20180016441A (enExample) |
| CN (1) | CN108271373B (enExample) |
| AU (2) | AU2016277449B2 (enExample) |
| CA (1) | CA2988841C (enExample) |
| CL (1) | CL2017003144A1 (enExample) |
| CO (1) | CO2017012675A2 (enExample) |
| CR (1) | CR20170559A (enExample) |
| DO (1) | DOP2017000287A (enExample) |
| EA (1) | EA036415B1 (enExample) |
| ES (1) | ES2849950T3 (enExample) |
| IL (1) | IL255978B (enExample) |
| MX (1) | MX389407B (enExample) |
| MY (1) | MY185816A (enExample) |
| NI (1) | NI201700156A (enExample) |
| NZ (1) | NZ738909A (enExample) |
| PE (1) | PE20180659A1 (enExample) |
| PH (1) | PH12017502259A1 (enExample) |
| SG (1) | SG10201911837SA (enExample) |
| SV (1) | SV2017005585A (enExample) |
| TN (1) | TN2017000519A1 (enExample) |
| TW (1) | TWI726889B (enExample) |
| WO (1) | WO2016198544A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3025592A1 (en) * | 2016-06-09 | 2017-12-14 | Medimmune Limited | Protease-resistant mono-lipidated peptides |
| MA50047A (fr) * | 2017-10-31 | 2020-07-08 | Medimmune Ltd | Administration orale d'analogues peptidiques de glp-1 |
| PE20211417A1 (es) | 2018-04-05 | 2021-08-02 | Sun Pharmaceutical Ind Ltd | Analogos novedosos de glp-1 |
| CA3204051A1 (en) | 2021-01-20 | 2022-07-28 | Brian Lian | Compositions and methods for the treatment of metabolic and liver disorders |
| WO2023044290A1 (en) | 2021-09-15 | 2023-03-23 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| TW202346323A (zh) * | 2022-02-07 | 2023-12-01 | 英商梅迪繆思有限公司 | 具有改善的生物穩定性的ｇｌｐ—１及升糖素雙重激動肽 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0154316B1 (en) | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemically modified lymphokine and production thereof |
| EP0401384B1 (en) | 1988-12-22 | 1996-03-13 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
| CA2497794A1 (en) | 2002-09-06 | 2004-03-18 | Bayer Pharmaceuticals Corporation | Modified glp-1 receptor agonists and their pharmacological methods of use |
| CN101010339B (zh) * | 2004-07-02 | 2011-11-09 | 布里斯托尔-迈尔斯斯奎布公司 | 人类胰高血糖素样肽-1调节剂及它们在治疗糖尿病及相关病况中的用途 |
| BRPI0615573A2 (pt) * | 2005-09-08 | 2011-05-24 | Tufts College | análogos de glp-1 estabilizados |
| EP1854455B1 (en) * | 2006-05-10 | 2009-10-07 | Biocompatibles UK Limited | Spherical microcapsules comprising GLP-1 peptides, their production and use |
| EP2021014A1 (en) | 2006-05-26 | 2009-02-11 | Brystol-Myers Squibb Company | Sustained release glp-1 receptor modulators |
| WO2008023050A1 (en) | 2006-08-25 | 2008-02-28 | Novo Nordisk A/S | Acylated exendin-4 compounds |
| DE602008005596D1 (de) | 2007-06-21 | 2011-04-28 | Univ Muenchen Tech | Biologisch aktive proteine mit erhöhter in-vivo- und/oder in-vitro-stabilität |
| CA2707448C (en) | 2007-12-11 | 2014-10-14 | Cadila Healthcare Limited | Peptidomimetics with glucagon antagonistic and glp-1 agonistic activities |
| US8685895B2 (en) * | 2008-12-05 | 2014-04-01 | Carolyn Enever | Methods for selecting protease resistant polypeptides |
| CN102459325B (zh) | 2009-06-16 | 2015-03-25 | 印第安纳大学科技研究有限公司 | 胃抑胜肽受体活化的胰高血糖素化合物 |
| WO2011048614A2 (en) | 2009-10-22 | 2011-04-28 | Cadila Healthcare Limited | Short chain peptidomimetics based orally active glp-1 agonist and glucagon receptor antagonist |
| EP2569000B1 (en) | 2010-05-13 | 2017-09-27 | Indiana University Research and Technology Corporation | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity |
| US20130143800A1 (en) | 2011-11-07 | 2013-06-06 | Research Development Foundation | Combination therapies to treat diabetes |
| AR092873A1 (es) | 2012-09-26 | 2015-05-06 | Cadila Healthcare Ltd | Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon |
| WO2014088631A1 (en) * | 2012-12-06 | 2014-06-12 | Stealth Peptides International, Inc. | Peptide therapeutics and methods for using same |
| HK1220383A1 (zh) * | 2013-03-14 | 2017-05-05 | Medimmune Limited | 用於治疗肥胖症的聚乙二醇化的胰高血糖素和glp-1共激动剂 |
| SG10201805039UA (en) | 2013-12-13 | 2018-07-30 | Medimmune Ltd | Protease resistant peptides |
-
2016
- 2016-06-08 TW TW105118294A patent/TWI726889B/zh not_active IP Right Cessation
- 2016-06-09 KR KR1020177037653A patent/KR20180016441A/ko not_active Ceased
- 2016-06-09 ES ES16732248T patent/ES2849950T3/es active Active
- 2016-06-09 WO PCT/EP2016/063206 patent/WO2016198544A1/en not_active Ceased
- 2016-06-09 NZ NZ738909A patent/NZ738909A/en not_active IP Right Cessation
- 2016-06-09 CR CR20170559A patent/CR20170559A/es unknown
- 2016-06-09 CA CA2988841A patent/CA2988841C/en active Active
- 2016-06-09 MY MYPI2017704708A patent/MY185816A/en unknown
- 2016-06-09 EP EP20202888.2A patent/EP3865504A1/en not_active Withdrawn
- 2016-06-09 US US15/579,774 patent/US10414811B2/en active Active
- 2016-06-09 SG SG10201911837SA patent/SG10201911837SA/en unknown
- 2016-06-09 JP JP2017563292A patent/JP6811190B2/ja active Active
- 2016-06-09 EP EP16732248.6A patent/EP3307769B1/en active Active
- 2016-06-09 AU AU2016277449A patent/AU2016277449B2/en not_active Ceased
- 2016-06-09 TN TNP/2017/000519A patent/TN2017000519A1/en unknown
- 2016-06-09 PE PE2017002540A patent/PE20180659A1/es unknown
- 2016-06-09 CN CN201680033320.4A patent/CN108271373B/zh active Active
- 2016-06-09 EA EA201792640A patent/EA036415B1/ru not_active IP Right Cessation
- 2016-06-09 MX MX2017015482A patent/MX389407B/es unknown
-
2017
- 2017-11-28 IL IL255978A patent/IL255978B/en active IP Right Grant
- 2017-12-07 CL CL2017003144A patent/CL2017003144A1/es unknown
- 2017-12-07 DO DO2017000287A patent/DOP2017000287A/es unknown
- 2017-12-08 SV SV2017005585A patent/SV2017005585A/es unknown
- 2017-12-11 NI NI201700156A patent/NI201700156A/es unknown
- 2017-12-11 PH PH12017502259A patent/PH12017502259A1/en unknown
- 2017-12-11 CO CONC2017/0012675A patent/CO2017012675A2/es unknown
-
2019
- 2019-07-25 US US16/521,662 patent/US20200079833A1/en not_active Abandoned
- 2019-09-13 AU AU2019229424A patent/AU2019229424A1/en not_active Abandoned
-
2021
- 2021-02-08 US US17/169,833 patent/US20210221866A1/en not_active Abandoned
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