JP2018518485A5 - - Google Patents
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- Publication number
- JP2018518485A5 JP2018518485A5 JP2017563292A JP2017563292A JP2018518485A5 JP 2018518485 A5 JP2018518485 A5 JP 2018518485A5 JP 2017563292 A JP2017563292 A JP 2017563292A JP 2017563292 A JP2017563292 A JP 2017563292A JP 2018518485 A5 JP2018518485 A5 JP 2018518485A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- peg
- pharmaceutical composition
- lipid
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562173631P | 2015-06-10 | 2015-06-10 | |
| US62/173,631 | 2015-06-10 | ||
| US201662343390P | 2016-05-31 | 2016-05-31 | |
| US62/343,390 | 2016-05-31 | ||
| PCT/EP2016/063206 WO2016198544A1 (en) | 2015-06-10 | 2016-06-09 | Protease-resistant lipidated glp-1 analogs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018518485A JP2018518485A (ja) | 2018-07-12 |
| JP2018518485A5 true JP2018518485A5 (enExample) | 2019-05-23 |
| JP6811190B2 JP6811190B2 (ja) | 2021-01-13 |
Family
ID=56235790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563292A Active JP6811190B2 (ja) | 2015-06-10 | 2016-06-09 | プロテアーゼ耐性脂質付加ｇｌｐ−１類似体 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US10414811B2 (enExample) |
| EP (2) | EP3865504A1 (enExample) |
| JP (1) | JP6811190B2 (enExample) |
| KR (1) | KR20180016441A (enExample) |
| CN (1) | CN108271373B (enExample) |
| AU (2) | AU2016277449B2 (enExample) |
| CA (1) | CA2988841C (enExample) |
| CL (1) | CL2017003144A1 (enExample) |
| CO (1) | CO2017012675A2 (enExample) |
| CR (1) | CR20170559A (enExample) |
| DO (1) | DOP2017000287A (enExample) |
| EA (1) | EA036415B1 (enExample) |
| ES (1) | ES2849950T3 (enExample) |
| IL (1) | IL255978B (enExample) |
| MX (1) | MX389407B (enExample) |
| MY (1) | MY185816A (enExample) |
| NI (1) | NI201700156A (enExample) |
| NZ (1) | NZ738909A (enExample) |
| PE (1) | PE20180659A1 (enExample) |
| PH (1) | PH12017502259A1 (enExample) |
| SG (1) | SG10201911837SA (enExample) |
| SV (1) | SV2017005585A (enExample) |
| TN (1) | TN2017000519A1 (enExample) |
| TW (1) | TWI726889B (enExample) |
| WO (1) | WO2016198544A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017277594A1 (en) * | 2016-06-09 | 2019-02-07 | Medimmune Limited | Protease-resistant mono-lipidated peptides |
| CN111655338A (zh) * | 2017-10-31 | 2020-09-11 | 免疫医疗有限公司 | Glp-1肽类似物的口服递送 |
| UA128210C2 (uk) | 2018-04-05 | 2024-05-08 | Сан Фармасьютікал Індастріз Лімітед | Аналог glp-1 |
| WO2022159395A1 (en) | 2021-01-20 | 2022-07-28 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| IL311411A (en) | 2021-09-15 | 2024-05-01 | Viking Therapeutics Inc | Preparations and methods for the treatment of metabolic and liver disorders |
| TW202346323A (zh) * | 2022-02-07 | 2023-12-01 | 英商梅迪繆思有限公司 | 具有改善的生物穩定性的ｇｌｐ—１及升糖素雙重激動肽 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0154316B1 (en) | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemically modified lymphokine and production thereof |
| WO1990006952A1 (fr) | 1988-12-22 | 1990-06-28 | Kirin-Amgen, Inc. | Facteur de stimulation de colonies de granulocytes modifies chimiquement |
| JP2006501820A (ja) | 2002-09-06 | 2006-01-19 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 修飾ｇｌｐ−１受容体アゴニストおよびそれらの薬理学的使用法 |
| CN101010339B (zh) * | 2004-07-02 | 2011-11-09 | 布里斯托尔-迈尔斯斯奎布公司 | 人类胰高血糖素样肽-1调节剂及它们在治疗糖尿病及相关病况中的用途 |
| KR20080052649A (ko) * | 2005-09-08 | 2008-06-11 | 트러스티즈 오브 터프츠 칼리지 | 안정화된 ｇｌｐ―1 유사체 |
| EP1854455B1 (en) * | 2006-05-10 | 2009-10-07 | Biocompatibles UK Limited | Spherical microcapsules comprising GLP-1 peptides, their production and use |
| WO2007139589A1 (en) | 2006-05-26 | 2007-12-06 | Bristol-Myers Squibb Company | Sustained release glp-1 receptor modulators |
| EP2057189B1 (en) | 2006-08-25 | 2013-03-06 | Novo Nordisk A/S | Acylated exendin-4 compounds |
| JP5351889B2 (ja) | 2007-06-21 | 2013-11-27 | テクニシェ ユニバーシタット ミュンヘン | インビボおよび／またはインビトロ安定性が増大した生物学的に活性なタンパク質 |
| KR101277560B1 (ko) | 2007-12-11 | 2013-06-25 | 카딜라 핼쓰캐어 리미티드 | 글루카곤 안타고니스트 활성 및 ｇｌｐ-1 아고니스트 활성의 펩티드 유사체 |
| WO2010063818A2 (en) * | 2008-12-05 | 2010-06-10 | Glaxo Group Limited | Methods for selecting protease resistant polypeptides |
| WO2010148089A1 (en) | 2009-06-16 | 2010-12-23 | Indiana University Research And Technology Corporation | Gip receptor-active glucagon compounds |
| US20120264685A1 (en) | 2009-10-22 | 2012-10-18 | Rajesh Bahekar | Short chain peptidomimetics based orally active glp 1 agonist and glucagon receptor antagonist |
| CA2797095A1 (en) | 2010-05-13 | 2011-11-17 | Indiana University Research And Technology Corporation | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity |
| US20130143800A1 (en) | 2011-11-07 | 2013-06-06 | Research Development Foundation | Combination therapies to treat diabetes |
| AR092873A1 (es) * | 2012-09-26 | 2015-05-06 | Cadila Healthcare Ltd | Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon |
| EP3459598A1 (en) | 2012-12-06 | 2019-03-27 | Stealth Peptides International, Inc. | Combinations of peptide therapeutics and methods for using same |
| AU2014230472A1 (en) * | 2013-03-14 | 2015-10-01 | Medimmune Limited | Pegylated glucagon and GLP-1 co-agonists for the treatment of obesity |
| KR20160098406A (ko) | 2013-12-13 | 2016-08-18 | 메디뮨 리미티드 | 프로테아제 내성 펩티드 |
-
2016
- 2016-06-08 TW TW105118294A patent/TWI726889B/zh not_active IP Right Cessation
- 2016-06-09 NZ NZ738909A patent/NZ738909A/en not_active IP Right Cessation
- 2016-06-09 EA EA201792640A patent/EA036415B1/ru not_active IP Right Cessation
- 2016-06-09 EP EP20202888.2A patent/EP3865504A1/en not_active Withdrawn
- 2016-06-09 TN TNP/2017/000519A patent/TN2017000519A1/en unknown
- 2016-06-09 CN CN201680033320.4A patent/CN108271373B/zh active Active
- 2016-06-09 PE PE2017002540A patent/PE20180659A1/es unknown
- 2016-06-09 CA CA2988841A patent/CA2988841C/en active Active
- 2016-06-09 ES ES16732248T patent/ES2849950T3/es active Active
- 2016-06-09 KR KR1020177037653A patent/KR20180016441A/ko not_active Ceased
- 2016-06-09 CR CR20170559A patent/CR20170559A/es unknown
- 2016-06-09 MX MX2017015482A patent/MX389407B/es unknown
- 2016-06-09 US US15/579,774 patent/US10414811B2/en active Active
- 2016-06-09 WO PCT/EP2016/063206 patent/WO2016198544A1/en not_active Ceased
- 2016-06-09 EP EP16732248.6A patent/EP3307769B1/en active Active
- 2016-06-09 MY MYPI2017704708A patent/MY185816A/en unknown
- 2016-06-09 AU AU2016277449A patent/AU2016277449B2/en not_active Ceased
- 2016-06-09 SG SG10201911837SA patent/SG10201911837SA/en unknown
- 2016-06-09 JP JP2017563292A patent/JP6811190B2/ja active Active
-
2017
- 2017-11-28 IL IL255978A patent/IL255978B/en active IP Right Grant
- 2017-12-07 DO DO2017000287A patent/DOP2017000287A/es unknown
- 2017-12-07 CL CL2017003144A patent/CL2017003144A1/es unknown
- 2017-12-08 SV SV2017005585A patent/SV2017005585A/es unknown
- 2017-12-11 CO CONC2017/0012675A patent/CO2017012675A2/es unknown
- 2017-12-11 NI NI201700156A patent/NI201700156A/es unknown
- 2017-12-11 PH PH12017502259A patent/PH12017502259A1/en unknown
-
2019
- 2019-07-25 US US16/521,662 patent/US20200079833A1/en not_active Abandoned
- 2019-09-13 AU AU2019229424A patent/AU2019229424A1/en not_active Abandoned
-
2021
- 2021-02-08 US US17/169,833 patent/US20210221866A1/en not_active Abandoned
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