JP2005534684A - Cxcケモカインレセプタ配位子としての3,4−二置換シクロブテン−1,2−ジオン - Google Patents
Cxcケモカインレセプタ配位子としての3,4−二置換シクロブテン−1,2−ジオン Download PDFInfo
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- JP2005534684A JP2005534684A JP2004524185A JP2004524185A JP2005534684A JP 2005534684 A JP2005534684 A JP 2005534684A JP 2004524185 A JP2004524185 A JP 2004524185A JP 2004524185 A JP2004524185 A JP 2004524185A JP 2005534684 A JP2005534684 A JP 2005534684A
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- 0 *c(cc[s]1)c1S(Cl)(=O)=O Chemical compound *c(cc[s]1)c1S(Cl)(=O)=O 0.000 description 33
- QZNPOXGYEULAKT-GFCCVEGCSA-N CC[C@H](c1cc(C(C)C)c[o]1)NC(C(C1=O)=O)=C1N(c1c[s]c(S(N(C)C)(=O)=O)c1O)N Chemical compound CC[C@H](c1cc(C(C)C)c[o]1)NC(C(C1=O)=O)=C1N(c1c[s]c(S(N(C)C)(=O)=O)c1O)N QZNPOXGYEULAKT-GFCCVEGCSA-N 0.000 description 1
- LPOURIULGAVACQ-SECBINFHSA-N CC[C@H](c1cc(C)c[o]1)N(C(C(C1=O)=O)=C1Nc1n[s]c(S(N(C)C)(=O)=O)c1O)N Chemical compound CC[C@H](c1cc(C)c[o]1)N(C(C(C1=O)=O)=C1Nc1n[s]c(S(N(C)C)(=O)=O)c1O)N LPOURIULGAVACQ-SECBINFHSA-N 0.000 description 1
- JWJPNWAZGOEMBS-CYBMUJFWSA-N CC[C@H](c1ccc(C)[o]1)N(C(C(C1=O)=O)=C1Nc1c[s]c(C(N(C)c2n[o]c(C)c2)=O)c1O)N Chemical compound CC[C@H](c1ccc(C)[o]1)N(C(C(C1=O)=O)=C1Nc1c[s]c(C(N(C)c2n[o]c(C)c2)=O)c1O)N JWJPNWAZGOEMBS-CYBMUJFWSA-N 0.000 description 1
- PKGBANIIRAUFIN-PLNGDYQASA-N COC/C=C\c1c(C=C)cc(CO)[o]1 Chemical compound COC/C=C\c1c(C=C)cc(CO)[o]1 PKGBANIIRAUFIN-PLNGDYQASA-N 0.000 description 1
- IXSBNNRUQYYMRM-UHFFFAOYSA-N COc(ccc(Br)c1)c1S(Cl)(=O)=O Chemical compound COc(ccc(Br)c1)c1S(Cl)(=O)=O IXSBNNRUQYYMRM-UHFFFAOYSA-N 0.000 description 1
- XZELWEMGWISCTP-UHFFFAOYSA-N COc1ccc2[o]c(C(O)=O)cc2c1 Chemical compound COc1ccc2[o]c(C(O)=O)cc2c1 XZELWEMGWISCTP-UHFFFAOYSA-N 0.000 description 1
- SRPFPHMGIHMKFR-UHFFFAOYSA-N Nc1c[s]c(S(c2ccccc2)(=O)=O)c1O Chemical compound Nc1c[s]c(S(c2ccccc2)(=O)=O)c1O SRPFPHMGIHMKFR-UHFFFAOYSA-N 0.000 description 1
- MFNWPSYQSIXEJA-UHFFFAOYSA-N Nc1cccc(S(c2ccccc2)(=O)=O)c1O Chemical compound Nc1cccc(S(c2ccccc2)(=O)=O)c1O MFNWPSYQSIXEJA-UHFFFAOYSA-N 0.000 description 1
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Nc1ccccc1 Chemical compound Nc1ccccc1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 1
- KYRDCNYOPTYZHK-UHFFFAOYSA-N Oc(ccc(Br)c1)c1S(c1ccccc1)(=O)=O Chemical compound Oc(ccc(Br)c1)c1S(c1ccccc1)(=O)=O KYRDCNYOPTYZHK-UHFFFAOYSA-N 0.000 description 1
- ZMVSJUCPNOBNIQ-UHFFFAOYSA-N [O-][N+](c1cc(Br)cc(S(c2ccccc2)(=O)=O)c1O)=O Chemical compound [O-][N+](c1cc(Br)cc(S(c2ccccc2)(=O)=O)c1O)=O ZMVSJUCPNOBNIQ-UHFFFAOYSA-N 0.000 description 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N c1cncnc1 Chemical compound c1cncnc1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 description 1
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| US10/208,412 US20040097547A1 (en) | 2001-04-16 | 2002-07-30 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| US10/241,326 US20040106794A1 (en) | 2001-04-16 | 2002-09-11 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| PCT/US2003/023785 WO2004011418A1 (en) | 2002-07-30 | 2003-07-30 | 3,4-di-substituted cyclobutene-1, 2-diones as cxc-chemokine receptor ligands |
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| JP2009538833A (ja) * | 2006-05-26 | 2009-11-12 | アボット・ラボラトリーズ | ポロ様キナーゼの阻害薬 |
| JP2010532356A (ja) * | 2007-07-03 | 2010-10-07 | シェーリング コーポレイション | 1,2−置換3,4−ジオキソ−1−シクロブテン化合物の合成のための方法および中間体 |
| JP2011529940A (ja) * | 2008-08-04 | 2011-12-15 | ノバルティス アーゲー | 有機化合物 |
| WO2016199906A1 (ja) * | 2015-06-12 | 2016-12-15 | 国立大学法人筑波大学 | スルホンアミド誘導体またはその薬学的に許容される酸付加塩 |
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| JP2009538833A (ja) * | 2006-05-26 | 2009-11-12 | アボット・ラボラトリーズ | ポロ様キナーゼの阻害薬 |
| JP2010532356A (ja) * | 2007-07-03 | 2010-10-07 | シェーリング コーポレイション | 1,2−置換3,4−ジオキソ−1−シクロブテン化合物の合成のための方法および中間体 |
| JP2011529940A (ja) * | 2008-08-04 | 2011-12-15 | ノバルティス アーゲー | 有機化合物 |
| WO2016199906A1 (ja) * | 2015-06-12 | 2016-12-15 | 国立大学法人筑波大学 | スルホンアミド誘導体またはその薬学的に許容される酸付加塩 |
| JPWO2016199906A1 (ja) * | 2015-06-12 | 2018-06-28 | 国立大学法人 筑波大学 | スルホンアミド誘導体またはその薬学的に許容される酸付加塩 |
| US10351522B2 (en) | 2015-06-12 | 2019-07-16 | University Of Tsukuba | Sulfonamide derivative and pharmaceutically acceptable acid addition salt thereof |
| JP2020521793A (ja) * | 2017-06-02 | 2020-07-27 | ユーシービー バイオファルマ エスアールエル | セレタリシブの結晶形態 |
| JP7264829B2 (ja) | 2017-06-02 | 2023-04-25 | ユーシービー バイオファルマ エスアールエル | セレタリシブの結晶形態 |
Also Published As
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| IL166427A0 (en) | 2006-01-15 |
| KR20050026060A (ko) | 2005-03-14 |
| US7947720B2 (en) | 2011-05-24 |
| US20070021494A1 (en) | 2007-01-25 |
| US7964646B2 (en) | 2011-06-21 |
| CA2496676C (en) | 2011-06-14 |
| MXPA05001274A (es) | 2005-09-08 |
| US20110213029A1 (en) | 2011-09-01 |
| WO2004011418A1 (en) | 2004-02-05 |
| EP1539678A1 (en) | 2005-06-15 |
| EP1539678B1 (en) | 2012-09-05 |
| US20090306079A1 (en) | 2009-12-10 |
| PL374876A1 (en) | 2005-11-14 |
| TW200716520A (en) | 2007-05-01 |
| NO20051036L (no) | 2005-04-20 |
| US20040106794A1 (en) | 2004-06-03 |
| AU2003259302B2 (en) | 2008-06-26 |
| AU2003259302A1 (en) | 2004-02-16 |
| BR0313109A (pt) | 2005-06-21 |
| CA2496676A1 (en) | 2004-02-05 |
| RU2005105692A (ru) | 2005-12-10 |
| NZ538521A (en) | 2008-02-29 |
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