MXPA04003439A - Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc. - Google Patents

Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc.

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Publication number
MXPA04003439A
MXPA04003439A MXPA04003439A MXPA04003439A MXPA04003439A MX PA04003439 A MXPA04003439 A MX PA04003439A MX PA04003439 A MXPA04003439 A MX PA04003439A MX PA04003439 A MXPA04003439 A MX PA04003439A MX PA04003439 A MXPA04003439 A MX PA04003439A
Authority
MX
Mexico
Prior art keywords
cxc
receptor antagonists
chemokine receptor
substituted maleimide
maleimide compounds
Prior art date
Application number
MXPA04003439A
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English (en)
Inventor
Arthur G Taveras
Original Assignee
Schering Corp
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Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MXPA04003439A publication Critical patent/MXPA04003439A/es

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/456—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
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Abstract

Se describen compuestos de la formula (I):(ver formula I),o una sal o solvato farmaceuticamente aceptable de los mismos; los compuestos son utiles para el tratamiento de enfermedades mediadas por quimiocina tales como trastornos inflamatorios agudos y cronicos y cancer.
MXPA04003439A 2001-10-12 2002-10-11 Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc. MXPA04003439A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32900501P 2001-10-12 2001-10-12
PCT/US2002/032628 WO2003031440A1 (en) 2001-10-12 2002-10-11 3,4-di-substituted maleimide compounds as cxc-chemokine receptor antagonists

Publications (1)

Publication Number Publication Date
MXPA04003439A true MXPA04003439A (es) 2004-07-08

Family

ID=23283431

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04003439A MXPA04003439A (es) 2001-10-12 2002-10-11 Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc.

Country Status (7)

Country Link
US (1) US6903131B2 (es)
EP (1) EP1434775A1 (es)
JP (1) JP2005505595A (es)
CN (1) CN1599734A (es)
CA (1) CA2462862A1 (es)
MX (1) MXPA04003439A (es)
WO (1) WO2003031440A1 (es)

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US6903131B2 (en) 2005-06-07

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