BR0313109A - Ciclobuteno-1,2-dionas 3,4-dissubstituìdas como ligandos de receptor de quimiocina de cxc - Google Patents
Ciclobuteno-1,2-dionas 3,4-dissubstituìdas como ligandos de receptor de quimiocina de cxcInfo
- Publication number
- BR0313109A BR0313109A BR0313109-2A BR0313109A BR0313109A BR 0313109 A BR0313109 A BR 0313109A BR 0313109 A BR0313109 A BR 0313109A BR 0313109 A BR0313109 A BR 0313109A
- Authority
- BR
- Brazil
- Prior art keywords
- diones
- cyclobutene
- disubstituted
- chemokine receptor
- receptor ligands
- Prior art date
Links
- 108091008928 CXC chemokine receptors Proteins 0.000 title 1
- 102000054900 CXCR Receptors Human genes 0.000 title 1
- RGBVWCQARBEPPW-UHFFFAOYSA-N cyclobut-3-ene-1,2-dione Chemical class O=C1C=CC1=O RGBVWCQARBEPPW-UHFFFAOYSA-N 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
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- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
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- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07C2601/14—The ring being saturated
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| US10/241,326 US20040106794A1 (en) | 2001-04-16 | 2002-09-11 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| PCT/US2003/023785 WO2004011418A1 (en) | 2002-07-30 | 2003-07-30 | 3,4-di-substituted cyclobutene-1, 2-diones as cxc-chemokine receptor ligands |
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-
2002
- 2002-09-11 US US10/241,326 patent/US20040106794A1/en not_active Abandoned
-
2003
- 2003-07-30 NZ NZ538521A patent/NZ538521A/en unknown
- 2003-07-30 CA CA2496676A patent/CA2496676C/en not_active Expired - Fee Related
- 2003-07-30 BR BR0313109-2A patent/BR0313109A/pt not_active IP Right Cessation
- 2003-07-30 MX MXPA05001274A patent/MXPA05001274A/es active IP Right Grant
- 2003-07-30 TW TW095140972A patent/TW200716520A/zh unknown
- 2003-07-30 WO PCT/US2003/023785 patent/WO2004011418A1/en not_active Ceased
- 2003-07-30 EP EP03772075A patent/EP1539678B1/en not_active Expired - Lifetime
- 2003-07-30 IL IL16642703A patent/IL166427A0/xx unknown
- 2003-07-30 RU RU2005105692/04A patent/RU2005105692A/ru not_active Application Discontinuation
- 2003-07-30 JP JP2004524185A patent/JP2005534684A/ja active Pending
- 2003-07-30 AU AU2003259302A patent/AU2003259302B2/en not_active Ceased
- 2003-07-30 PL PL03374876A patent/PL374876A1/xx not_active Application Discontinuation
- 2003-07-30 KR KR1020057001672A patent/KR20050026060A/ko not_active Ceased
-
2005
- 2005-02-25 NO NO20051036A patent/NO20051036L/no not_active Application Discontinuation
-
2006
- 2006-08-08 US US11/500,739 patent/US7964646B2/en not_active Expired - Fee Related
-
2009
- 2009-01-13 US US12/352,781 patent/US7947720B2/en not_active Expired - Fee Related
-
2011
- 2011-05-06 US US13/102,554 patent/US20110213029A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL166427A0 (en) | 2006-01-15 |
| KR20050026060A (ko) | 2005-03-14 |
| US7947720B2 (en) | 2011-05-24 |
| US20070021494A1 (en) | 2007-01-25 |
| US7964646B2 (en) | 2011-06-21 |
| CA2496676C (en) | 2011-06-14 |
| MXPA05001274A (es) | 2005-09-08 |
| US20110213029A1 (en) | 2011-09-01 |
| WO2004011418A1 (en) | 2004-02-05 |
| EP1539678A1 (en) | 2005-06-15 |
| EP1539678B1 (en) | 2012-09-05 |
| US20090306079A1 (en) | 2009-12-10 |
| PL374876A1 (en) | 2005-11-14 |
| TW200716520A (en) | 2007-05-01 |
| NO20051036L (no) | 2005-04-20 |
| US20040106794A1 (en) | 2004-06-03 |
| AU2003259302B2 (en) | 2008-06-26 |
| AU2003259302A1 (en) | 2004-02-16 |
| CA2496676A1 (en) | 2004-02-05 |
| RU2005105692A (ru) | 2005-12-10 |
| JP2005534684A (ja) | 2005-11-17 |
| NZ538521A (en) | 2008-02-29 |
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