MA40524A - Dérivés d'adrénomédulline stabilisés et leur utilisation - Google Patents
Dérivés d'adrénomédulline stabilisés et leur utilisationInfo
- Publication number
- MA40524A MA40524A MA040524A MA40524A MA40524A MA 40524 A MA40524 A MA 40524A MA 040524 A MA040524 A MA 040524A MA 40524 A MA40524 A MA 40524A MA 40524 A MA40524 A MA 40524A
- Authority
- MA
- Morocco
- Prior art keywords
- adrenomedulline
- stabilized
- derivatives
- stabilized adrenomedulline
- adrenomedulline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14186572 | 2014-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA40524A true MA40524A (fr) | 2021-03-17 |
Family
ID=51610047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA040524A MA40524A (fr) | 2014-09-26 | 2015-09-24 | Dérivés d'adrénomédulline stabilisés et leur utilisation |
Country Status (24)
Country | Link |
---|---|
US (1) | US20180022780A1 (fr) |
EP (1) | EP3197481A1 (fr) |
JP (1) | JP2018500272A (fr) |
KR (1) | KR20170062490A (fr) |
CN (1) | CN107001440A (fr) |
AP (1) | AP2017009826A0 (fr) |
AU (1) | AU2015323769A1 (fr) |
CA (1) | CA2962486A1 (fr) |
CO (1) | CO2017002813A2 (fr) |
CR (1) | CR20170110A (fr) |
CU (1) | CU20170038A7 (fr) |
DO (1) | DOP2017000085A (fr) |
EA (1) | EA201790699A1 (fr) |
EC (1) | ECSP17018513A (fr) |
IL (1) | IL250927A0 (fr) |
MA (1) | MA40524A (fr) |
MX (1) | MX2017003897A (fr) |
NI (1) | NI201700036A (fr) |
PE (1) | PE20170702A1 (fr) |
PH (1) | PH12017500563A1 (fr) |
SG (1) | SG11201701803XA (fr) |
TN (1) | TN2017000109A1 (fr) |
WO (1) | WO2016046301A1 (fr) |
ZA (1) | ZA201702901B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7001285B2 (ja) * | 2017-03-29 | 2022-01-19 | 国立大学法人 宮崎大学 | 長時間作用型アドレノメデュリン誘導体 |
NL2020518B1 (en) * | 2018-03-02 | 2019-09-12 | Mimetas B V | Device and method for performing electrical measurements |
WO2020254197A1 (fr) * | 2019-06-18 | 2020-12-24 | Bayer Aktiengesellschaft | Analogues d'adrénomédulline pour stabilisation à long terme et leur utilisation |
MX2022012332A (es) * | 2020-04-03 | 2022-10-27 | Bayer Ag | Formulaciones farmaceuticas liquidas de profarmacos a base de polietilenglicol de adrenomedulina y su uso. |
JPWO2022177018A1 (fr) * | 2021-02-22 | 2022-08-25 |
Family Cites Families (82)
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WO1988007089A1 (fr) | 1987-03-18 | 1988-09-22 | Medical Research Council | Anticorps alteres |
US4812590A (en) | 1987-06-25 | 1989-03-14 | Merck & Co., Inc. | Carbamates of 4-hydroxyanisole as prodrugs for chemotherapy of melanoma |
US6780613B1 (en) | 1988-10-28 | 2004-08-24 | Genentech, Inc. | Growth hormone variants |
US5846951A (en) | 1991-06-06 | 1998-12-08 | The School Of Pharmacy, University Of London | Pharmaceutical compositions |
JP2774769B2 (ja) * | 1993-04-26 | 1998-07-09 | 賢治 寒川 | アドレノメデュリン |
US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
GB9422383D0 (en) | 1994-11-05 | 1995-01-04 | Wellcome Found | Antibodies |
US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
US5739277A (en) | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
JPH11171896A (ja) * | 1995-09-19 | 1999-06-29 | Kirin Brewery Co Ltd | 新規ペプチド化合物およびその医薬組成物 |
DE69738522T2 (de) | 1996-08-02 | 2009-04-02 | Bristol-Myers Squibb Co. | Ein verfahren zur inhibierung immunglobulininduzierter toxizität aufgrund von der verwendung von immunoglobinen in therapie und in vivo diagnostik |
WO1998023289A1 (fr) | 1996-11-27 | 1998-06-04 | The General Hospital Corporation | Modulation de la fixation de l'igg au fcrn |
US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
US6624142B2 (en) | 1997-12-30 | 2003-09-23 | Enzon, Inc. | Trimethyl lock based tetrapartate prodrugs |
DE69937291T2 (de) | 1998-04-02 | 2008-07-10 | Genentech, Inc., South San Francisco | Antikörpervarianten und fragmente davon |
US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
US6528624B1 (en) | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
US6242195B1 (en) | 1998-04-02 | 2001-06-05 | Genentech, Inc. | Methods for determining binding of an analyte to a receptor |
GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
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EP1006183A1 (fr) | 1998-12-03 | 2000-06-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Récepteurs Fc recombinantes et solubles |
KR20060067983A (ko) | 1999-01-15 | 2006-06-20 | 제넨테크, 인크. | 효과기 기능이 변화된 폴리펩티드 변이체 |
US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
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US20040106794A1 (en) | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
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US20040002587A1 (en) | 2002-02-20 | 2004-01-01 | Watkins Jeffry D. | Fc region variants |
US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
AU2003209446B2 (en) | 2002-03-01 | 2008-09-25 | Immunomedics, Inc. | Bispecific antibody point mutations for enhancing rate of clearance |
DK1534335T4 (en) | 2002-08-14 | 2015-10-05 | Macrogenics Inc | FCGAMMARIIB-SPECIFIC ANTIBODIES AND PROCEDURES FOR USE THEREOF |
WO2004019993A1 (fr) | 2002-08-30 | 2004-03-11 | Ramot At Tel Aviv University Ltd. | Dendrimeres auto-immolateurs liberant plusieurs fragments actifs lors d'un seul evenement activateur |
EP3502133A1 (fr) | 2002-09-27 | 2019-06-26 | Xencor, Inc. | Variantes fc optimisées et leurs procédés de génération |
AU2003286467B2 (en) | 2002-10-15 | 2009-10-01 | Abbvie Biotherapeutics Inc. | Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis |
GB2395337B (en) | 2002-11-14 | 2005-12-28 | Gary Michael Wilson | Warning Unit |
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US8388955B2 (en) | 2003-03-03 | 2013-03-05 | Xencor, Inc. | Fc variants |
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RU2333223C2 (ru) | 2003-08-12 | 2008-09-10 | Лайпоксен Текнолоджиз Лимитед | Альдегидные производные сиаловой кислоты, способы их получения, конъюгаты альдегидных производных сиаловой кислоты и фармацевтическая композиция на их основе |
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US20050249723A1 (en) | 2003-12-22 | 2005-11-10 | Xencor, Inc. | Fc polypeptides with novel Fc ligand binding sites |
CN1918178B (zh) | 2004-01-12 | 2012-08-22 | 应用分子进化公司 | Fc区变体 |
WO2005099768A2 (fr) | 2004-03-23 | 2005-10-27 | Complex Biosystems Gmbh | Lieur de promedicaments |
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DK1749026T3 (da) | 2004-05-24 | 2012-02-27 | Inst Cardiologie Montreal | Mærkede adrenomedullinderivater og deres anvendelse til billeddannelse og terapi |
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DK2173890T3 (da) | 2007-06-21 | 2011-06-27 | Univ Muenchen Tech | Biologisk aktive proteiner med forhøjet stabilitet in vivo og/eller in vitro |
ES2354488T3 (es) * | 2008-04-18 | 2011-03-15 | F. Hoffmann-La Roche Ag | Alfa-n-metilación de aminoácidos. |
EP2306986B1 (fr) | 2008-06-26 | 2018-03-21 | Prolynx Llc | Promédicaments et conjugués médicament-macromolécule ayant des taux de libération de médicament contrôlés |
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PE20121539A1 (es) | 2009-06-08 | 2012-12-06 | Amunix Operating Inc | Polipeptidos de la hormona de crecimiento y metodos de preparacion |
AU2010258898B8 (en) | 2009-06-08 | 2015-02-05 | Amunix Operating Inc. | Glucose-regulating polypeptides and methods of making and using same |
EP2470559B1 (fr) | 2009-08-24 | 2017-03-22 | Amunix Operating Inc. | Compositions de facteur ix de coagulation et leurs procédés de fabrication et d'utilisation |
WO2011028344A2 (fr) | 2009-08-25 | 2011-03-10 | Amunix Operating Inc. | Compositions d'antagonistes des récepteurs d'interleukine-1 et leurs procédés de préparation et d'utilisation |
JP6143740B2 (ja) * | 2011-04-07 | 2017-06-07 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 持続性ペプチド類似体 |
KR20150000464A (ko) | 2011-11-03 | 2015-01-02 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 펩티드의 방출가능한 연결을 위한 티로신 기재의 링커 |
JOP20190001B1 (ar) * | 2011-11-03 | 2022-03-14 | Bayer Pharma AG | عقار أولي معتمد على جليكول عديد إثيلين من أدرينومدالين واستخدامه |
-
2015
- 2015-09-24 CU CUP2017000038A patent/CU20170038A7/xx unknown
- 2015-09-24 AU AU2015323769A patent/AU2015323769A1/en not_active Abandoned
- 2015-09-24 SG SG11201701803XA patent/SG11201701803XA/en unknown
- 2015-09-24 CA CA2962486A patent/CA2962486A1/fr not_active Abandoned
- 2015-09-24 JP JP2017516055A patent/JP2018500272A/ja active Pending
- 2015-09-24 PE PE2017000514A patent/PE20170702A1/es not_active Application Discontinuation
- 2015-09-24 TN TN2017000109A patent/TN2017000109A1/en unknown
- 2015-09-24 AP AP2017009826A patent/AP2017009826A0/en unknown
- 2015-09-24 CR CR20170110A patent/CR20170110A/es unknown
- 2015-09-24 MA MA040524A patent/MA40524A/fr unknown
- 2015-09-24 US US15/514,456 patent/US20180022780A1/en not_active Abandoned
- 2015-09-24 MX MX2017003897A patent/MX2017003897A/es unknown
- 2015-09-24 EA EA201790699A patent/EA201790699A1/ru unknown
- 2015-09-24 KR KR1020177010819A patent/KR20170062490A/ko unknown
- 2015-09-24 WO PCT/EP2015/071941 patent/WO2016046301A1/fr active Application Filing
- 2015-09-24 CN CN201580063852.8A patent/CN107001440A/zh active Pending
- 2015-09-24 EP EP15767164.5A patent/EP3197481A1/fr not_active Withdrawn
-
2017
- 2017-03-05 IL IL250927A patent/IL250927A0/en unknown
- 2017-03-24 DO DO2017000085A patent/DOP2017000085A/es unknown
- 2017-03-24 EC ECIEPI201718513A patent/ECSP17018513A/es unknown
- 2017-03-24 NI NI201700036A patent/NI201700036A/es unknown
- 2017-03-24 PH PH12017500563A patent/PH12017500563A1/en unknown
- 2017-03-24 CO CONC2017/0002813A patent/CO2017002813A2/es unknown
- 2017-04-25 ZA ZA2017/02901A patent/ZA201702901B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AP2017009826A0 (en) | 2017-03-31 |
EA201790699A1 (ru) | 2017-10-31 |
CU20170038A7 (es) | 2017-10-05 |
EP3197481A1 (fr) | 2017-08-02 |
NI201700036A (es) | 2017-06-16 |
CN107001440A (zh) | 2017-08-01 |
WO2016046301A1 (fr) | 2016-03-31 |
IL250927A0 (en) | 2017-04-30 |
US20180022780A1 (en) | 2018-01-25 |
SG11201701803XA (en) | 2017-04-27 |
CA2962486A1 (fr) | 2016-03-31 |
MX2017003897A (es) | 2017-06-28 |
CO2017002813A2 (es) | 2017-06-30 |
ECSP17018513A (es) | 2017-05-31 |
KR20170062490A (ko) | 2017-06-07 |
ZA201702901B (en) | 2019-06-26 |
DOP2017000085A (es) | 2017-04-30 |
AU2015323769A1 (en) | 2017-04-13 |
JP2018500272A (ja) | 2018-01-11 |
PE20170702A1 (es) | 2017-06-24 |
TN2017000109A1 (en) | 2018-07-04 |
PH12017500563A1 (en) | 2017-08-30 |
CR20170110A (es) | 2017-05-08 |
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