|
US5741908A
(en)
|
1996-06-21 |
1998-04-21 |
Minnesota Mining And Manufacturing Company |
Process for reparing imidazoquinolinamines
|
|
UA67760C2
(uk)
*
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
|
US6518280B2
(en)
|
1998-12-11 |
2003-02-11 |
3M Innovative Properties Company |
Imidazonaphthyridines
|
|
US20020058674A1
(en)
|
1999-01-08 |
2002-05-16 |
Hedenstrom John C. |
Systems and methods for treating a mucosal surface
|
|
US6558951B1
(en)
*
|
1999-02-11 |
2003-05-06 |
3M Innovative Properties Company |
Maturation of dendritic cells with immune response modifying compounds
|
|
US6573273B1
(en)
*
|
1999-06-10 |
2003-06-03 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
|
US6756382B2
(en)
|
1999-06-10 |
2004-06-29 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
|
US6331539B1
(en)
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
US6541485B1
(en)
|
1999-06-10 |
2003-04-01 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
|
US6916925B1
(en)
|
1999-11-05 |
2005-07-12 |
3M Innovative Properties Co. |
Dye labeled imidazoquinoline compounds
|
|
US6376669B1
(en)
|
1999-11-05 |
2002-04-23 |
3M Innovative Properties Company |
Dye labeled imidazoquinoline compounds
|
|
JP3436512B2
(ja)
*
|
1999-12-28 |
2003-08-11 |
株式会社デンソー |
アクセル装置
|
|
US6667312B2
(en)
*
|
2000-12-08 |
2003-12-23 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
|
JP2008531580A
(ja)
*
|
2000-12-08 |
2008-08-14 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫応答修飾因子の標的化送達のための組成物および方法
|
|
US6545017B1
(en)
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Urea substituted imidazopyridines
|
|
EP1360486A2
(en)
*
|
2000-12-08 |
2003-11-12 |
3M Innovative Properties Company |
Screening method for identifying compounds that selectively induce interferon alpha
|
|
US6664264B2
(en)
*
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
|
US6664260B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Heterocyclic ether substituted imidazoquinolines
|
|
US6660747B2
(en)
*
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
|
US6660735B2
(en)
*
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Urea substituted imidazoquinoline ethers
|
|
UA74852C2
(en)
*
|
2000-12-08 |
2006-02-15 |
3M Innovative Properties Co |
Urea-substituted imidazoquinoline ethers
|
|
US6545016B1
(en)
*
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Amide substituted imidazopyridines
|
|
US6677347B2
(en)
*
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamido ether substituted imidazoquinolines
|
|
US20020107262A1
(en)
*
|
2000-12-08 |
2002-08-08 |
3M Innovative Properties Company |
Substituted imidazopyridines
|
|
US6525064B1
(en)
|
2000-12-08 |
2003-02-25 |
3M Innovative Properties Company |
Sulfonamido substituted imidazopyridines
|
|
US6664265B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
|
UA74593C2
(en)
*
|
2000-12-08 |
2006-01-16 |
3M Innovative Properties Co |
Substituted imidazopyridines
|
|
US6677348B2
(en)
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Aryl ether substituted imidazoquinolines
|
|
US7226928B2
(en)
*
|
2001-06-15 |
2007-06-05 |
3M Innovative Properties Company |
Methods for the treatment of periodontal disease
|
|
WO2003020889A2
(en)
*
|
2001-08-30 |
2003-03-13 |
3M Innovative Properties Company |
Methods of maturing plasmacytoid dendritic cells using immune response modifier molecules
|
|
EP1455700A4
(en)
*
|
2001-11-16 |
2007-02-14 |
3M Innovative Properties Co |
METHODS AND COMPOSITIONS RELATED TO MRI COMPOUNDS AND TO TOLL-TYPE RECEPTOR (TLR) PATHWAYS
|
|
CA2467828C
(en)
*
|
2001-11-29 |
2011-10-04 |
3M Innovative Properties Company |
Pharmaceutical formulations comprising an immune response modifier
|
|
CA2365732A1
(en)
*
|
2001-12-20 |
2003-06-20 |
Ibm Canada Limited-Ibm Canada Limitee |
Testing measurements
|
|
US6677349B1
(en)
*
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
WO2003072026A2
(en)
*
|
2002-02-22 |
2003-09-04 |
3M Innovative Properties Company |
Method of reducing and treating uvb-induced immunosuppression
|
|
DE60335350D1
(de)
*
|
2002-03-19 |
2011-01-27 |
Powderject Res Ltd |
Adjuvantien für dns impstoffe basierend auf imidazochinoline
|
|
EP1487486B1
(en)
*
|
2002-03-19 |
2009-01-14 |
PowderJect Research Limited |
Imidazoquinolineamines as adjuvants in hiv dna vaccination
|
|
EP1376872B1
(de)
*
|
2002-05-07 |
2007-10-10 |
Schott Ag |
Beleuchtungseinrichtung für Schaltflächen
|
|
GB0211649D0
(en)
|
2002-05-21 |
2002-07-03 |
Novartis Ag |
Organic compounds
|
|
AU2003237386A1
(en)
|
2002-06-07 |
2003-12-22 |
3M Innovative Properties Company |
Ether substituted imidazopyridines
|
|
WO2004032829A2
(en)
|
2002-08-15 |
2004-04-22 |
3M Innovative Properties Company |
Immunostimulatory compositions and methods of stimulating an immune response
|
|
JP2006503068A
(ja)
*
|
2002-09-26 |
2006-01-26 |
スリーエム イノベイティブ プロパティズ カンパニー |
1h−イミダゾダイマー
|
|
US7094807B2
(en)
|
2002-11-19 |
2006-08-22 |
Achillion Pharmaceuticals, Inc. |
Substituted aryl thioureas and related compounds; inhibitors of viral replication
|
|
WO2004053452A2
(en)
*
|
2002-12-11 |
2004-06-24 |
3M Innovative Properties Company |
Assays relating to toll-like receptor activity
|
|
AU2003287324A1
(en)
*
|
2002-12-11 |
2004-06-30 |
3M Innovative Properties Company |
Gene expression systems and recombinant cell lines
|
|
EP1590348A1
(en)
|
2002-12-20 |
2005-11-02 |
3M Innovative Properties Company |
Aryl / hetaryl substituted imidazoquinolines
|
|
WO2004060319A2
(en)
|
2002-12-30 |
2004-07-22 |
3M Innovative Properties Company |
Immunostimulatory combinations
|
|
US7375180B2
(en)
*
|
2003-02-13 |
2008-05-20 |
3M Innovative Properties Company |
Methods and compositions related to IRM compounds and Toll-like receptor 8
|
|
US7485432B2
(en)
*
|
2003-02-27 |
2009-02-03 |
3M Innovative Properties Company |
Selective modulation of TLR-mediated biological activity
|
|
JP2006519866A
(ja)
|
2003-03-04 |
2006-08-31 |
スリーエム イノベイティブ プロパティズ カンパニー |
Uv誘発性の表皮の新形成の予防的治療
|
|
AU2004220534A1
(en)
*
|
2003-03-07 |
2004-09-23 |
3M Innovative Properties Company |
1-amino 1H-imidazoquinolines
|
|
US7163947B2
(en)
*
|
2003-03-07 |
2007-01-16 |
3M Innovative Properties Company |
1-Amino 1H-imidazoquinolines
|
|
JP2006523212A
(ja)
*
|
2003-03-13 |
2006-10-12 |
スリーエム イノベイティブ プロパティズ カンパニー |
皮膚病変の診断方法
|
|
ATE556711T1
(de)
*
|
2003-03-13 |
2012-05-15 |
3M Innovative Properties Co |
Verfahren zur verbesserung der hautqualität
|
|
US7179253B2
(en)
|
2003-03-13 |
2007-02-20 |
3M Innovative Properties Company |
Method of tattoo removal
|
|
EP1613956A2
(en)
*
|
2003-03-25 |
2006-01-11 |
3M Innovative Properties Company |
Selective activation of cellular activities mediated through a common toll-like receptor
|
|
US20040192585A1
(en)
|
2003-03-25 |
2004-09-30 |
3M Innovative Properties Company |
Treatment for basal cell carcinoma
|
|
WO2004108072A2
(en)
*
|
2003-04-10 |
2004-12-16 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds using metal-containing particulate support materials
|
|
US20040265351A1
(en)
*
|
2003-04-10 |
2004-12-30 |
Miller Richard L. |
Methods and compositions for enhancing immune response
|
|
US20050032829A1
(en)
*
|
2003-06-06 |
2005-02-10 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
|
US6943255B2
(en)
*
|
2003-06-06 |
2005-09-13 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
|
MY157827A
(en)
*
|
2003-06-27 |
2016-07-29 |
3M Innovative Properties Co |
Sulfonamide substituted imidazoquinolines
|
|
JP2007500712A
(ja)
*
|
2003-07-31 |
2007-01-18 |
スリーエム イノベイティブ プロパティズ カンパニー |
カプセル化および徐放のための組成物
|
|
WO2005016275A2
(en)
*
|
2003-08-05 |
2005-02-24 |
3M Innovative Properties Company |
Formulations containing an immune response modifier
|
|
WO2005018551A2
(en)
*
|
2003-08-12 |
2005-03-03 |
3M Innovative Properties Company |
Oxime substituted imidazo-containing compounds
|
|
ES2545826T3
(es)
*
|
2003-08-14 |
2015-09-16 |
3M Innovative Properties Company |
Modificadores de la respuesta inmune modificados con lípidos
|
|
CA2535338C
(en)
|
2003-08-14 |
2013-05-28 |
3M Innovative Properties Company |
Substituted 1h-imidazo[4,5-c]pyridin-4-amines,1h-imidazo[4,5-c]quinolin -4-amines and 1h-imidazo[4,5-c]naphthyridin-4-amines as immune response modifiers
|
|
EP1658035A4
(en)
|
2003-08-25 |
2007-08-22 |
3M Innovative Properties Co |
ADMINISTRATION OF MODIFIERS OF IMMUNE RESPONSE
|
|
WO2005018574A2
(en)
*
|
2003-08-25 |
2005-03-03 |
3M Innovative Properties Company |
Immunostimulatory combinations and treatments
|
|
CA2536136C
(en)
|
2003-08-27 |
2012-10-30 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted imidazoquinolines
|
|
CA2536578A1
(en)
*
|
2003-09-02 |
2005-03-10 |
3M Innovative Properties Company |
Methods related to the treatment of mucosal associated conditions
|
|
WO2005023190A2
(en)
|
2003-09-05 |
2005-03-17 |
3M Innovative Properties Company |
Treatment for cd5+ b cell lymphoma
|
|
US20050059072A1
(en)
*
|
2003-09-17 |
2005-03-17 |
3M Innovative Properties Company |
Selective modulation of TLR gene expression
|
|
US8871782B2
(en)
|
2003-10-03 |
2014-10-28 |
3M Innovative Properties Company |
Alkoxy substituted imidazoquinolines
|
|
EP1696912B1
(en)
|
2003-10-03 |
2016-05-11 |
3M Innovative Properties Company |
Pyrazolopyridines and analogs thereof
|
|
US7544697B2
(en)
|
2003-10-03 |
2009-06-09 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and analogs thereof
|
|
US20050096259A1
(en)
*
|
2003-10-31 |
2005-05-05 |
3M Innovative Properties Company |
Neutrophil activation by immune response modifier compounds
|
|
CA2545825A1
(en)
|
2003-11-14 |
2005-06-02 |
3M Innovative Properties Company |
Hydroxylamine substituted imidazo ring compounds
|
|
EP1685129A4
(en)
*
|
2003-11-14 |
2008-10-22 |
3M Innovative Properties Co |
OXIMSUBSTITUTED IMIDAZORING CONNECTIONS
|
|
BRPI0416801A
(pt)
*
|
2003-11-21 |
2007-01-09 |
Novartis Ag |
derivados de 1h-imidazoquinolina como inibidores de proteìna sinase
|
|
AR046845A1
(es)
*
|
2003-11-21 |
2005-12-28 |
Novartis Ag |
Derivados de 1h-imidazo[4,5-c]quinolina para tratamiento de enfermedades dependientes de las proteino-quinasas
|
|
MY161812A
(en)
|
2003-11-25 |
2017-05-15 |
3M Innovative Properties Co |
Substituted imidazo ring systems and methods
|
|
EP1686992A4
(en)
*
|
2003-11-25 |
2009-11-04 |
3M Innovative Properties Co |
HYDROXYLAMINE, AND IMIDAZOQUINOLEINS, AND IMIDAZOPYRIDINES AND IMIDAZONAPHTYRIDINE SUBSTITUTED WITH OXIME
|
|
WO2005055932A2
(en)
*
|
2003-12-02 |
2005-06-23 |
3M Innovative Properties Company |
Therapeutic combinations and methods including irm compounds
|
|
US20050226878A1
(en)
*
|
2003-12-02 |
2005-10-13 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
|
AU2004315771A1
(en)
*
|
2003-12-04 |
2005-08-25 |
3M Innovative Properties Company |
Sulfone substituted imidazo ring ethers
|
|
JP2007517035A
(ja)
|
2003-12-29 |
2007-06-28 |
スリーエム イノベイティブ プロパティズ カンパニー |
アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン
|
|
CA2552101A1
(en)
*
|
2003-12-29 |
2005-07-21 |
3M Innovative Properties Company |
Piperazine, [1,4]diazepane, [1,4]diazocane, and [1,5]diazocane fused imidazo ring compounds
|
|
JP2007517044A
(ja)
*
|
2003-12-30 |
2007-06-28 |
スリーエム イノベイティブ プロパティズ カンパニー |
イミダゾキノリニル、イミダゾピリジニル、およびイミダゾナフチリジニルスルホンアミド
|
|
WO2005065678A1
(en)
*
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Immunomodulatory combinations
|
|
ES2665342T3
(es)
|
2004-03-15 |
2018-04-25 |
Meda Ab |
Formulaciones y métodos para modificadores de la respuesta inmune
|
|
TW200612932A
(en)
|
2004-03-24 |
2006-05-01 |
3M Innovative Properties Co |
Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
|
WO2005092893A1
(ja)
|
2004-03-26 |
2005-10-06 |
Dainippon Sumitomo Pharma Co., Ltd. |
9置換−8−オキソアデニン化合物
|
|
JP2007532572A
(ja)
*
|
2004-04-09 |
2007-11-15 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫反応調整剤を送達させるための方法、組成物および調製物
|
|
WO2006126981A2
(en)
*
|
2004-04-28 |
2006-11-30 |
3M Innovative Properties Company |
Compositions and methods for mucosal vaccination
|
|
TW200600492A
(en)
*
|
2004-05-18 |
2006-01-01 |
Achillion Pharmaceuticals Inc |
Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
|
|
WO2005123079A2
(en)
*
|
2004-06-14 |
2005-12-29 |
3M Innovative Properties Company |
Urea substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
|
US8017779B2
(en)
|
2004-06-15 |
2011-09-13 |
3M Innovative Properties Company |
Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
|
WO2006009826A1
(en)
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
US7915281B2
(en)
|
2004-06-18 |
2011-03-29 |
3M Innovative Properties Company |
Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
|
|
AU2005283085B2
(en)
*
|
2004-06-18 |
2012-06-21 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
US20070259881A1
(en)
*
|
2004-06-18 |
2007-11-08 |
Dellaria Joseph F Jr |
Substituted Imidazo Ring Systems and Methods
|
|
US7897609B2
(en)
|
2004-06-18 |
2011-03-01 |
3M Innovative Properties Company |
Aryl substituted imidazonaphthyridines
|
|
US8541438B2
(en)
|
2004-06-18 |
2013-09-24 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
EP1786450A4
(en)
*
|
2004-08-27 |
2009-11-11 |
3M Innovative Properties Co |
HIV IMMUNOSTIMATORY COMPOSITIONS
|
|
AU2005282523A1
(en)
|
2004-09-02 |
2006-03-16 |
3M Innovative Properties Company |
2-amino 1H imidazo ring systems and methods
|
|
ES2384390T3
(es)
*
|
2004-09-02 |
2012-07-04 |
3M Innovative Properties Company |
Sistemas cíclicos 1-alcoxi-1H-imidazo y métodos asociados
|
|
WO2006029223A2
(en)
*
|
2004-09-08 |
2006-03-16 |
Children's Medical Center Corporation |
Method for stimulating the immune response of newborns
|
|
WO2006042254A2
(en)
*
|
2004-10-08 |
2006-04-20 |
3M Innovative Properties Company |
Adjuvant for dna vaccines
|
|
US8080560B2
(en)
|
2004-12-17 |
2011-12-20 |
3M Innovative Properties Company |
Immune response modifier formulations containing oleic acid and methods
|
|
CA2592904C
(en)
|
2004-12-30 |
2015-04-07 |
3M Innovative Properties Company |
Chiral fused [1,2]imidazo[4,5-c] ring compounds
|
|
EP1835915A4
(en)
*
|
2004-12-30 |
2010-02-24 |
Coley Pharm Group Inc |
FORMULATIONS AND METHOD FOR MODIFYING THE IMMUNE RESPONSE
|
|
CA2592897A1
(en)
*
|
2004-12-30 |
2006-07-13 |
Takeda Pharmaceutical Company Limited |
1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine ethanesulfonate and 1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine methanesulfonate
|
|
US8436176B2
(en)
*
|
2004-12-30 |
2013-05-07 |
Medicis Pharmaceutical Corporation |
Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine
|
|
US8461174B2
(en)
|
2004-12-30 |
2013-06-11 |
3M Innovative Properties Company |
Treatment for cutaneous metastases
|
|
JP5313502B2
(ja)
|
2004-12-30 |
2013-10-09 |
スリーエム イノベイティブ プロパティズ カンパニー |
置換キラル縮合[1,2]イミダゾ[4,5−c]環状化合物
|
|
AU2006210392A1
(en)
|
2005-02-04 |
2006-08-10 |
Coley Pharmaceutical Group, Inc. |
Aqueous gel formulations containing immune response modifiers
|
|
WO2006086449A2
(en)
|
2005-02-09 |
2006-08-17 |
Coley Pharmaceutical Group, Inc. |
Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
CA2602083A1
(en)
|
2005-02-09 |
2006-08-09 |
Coley Pharmaceutical Group, Inc. |
Oxime and hydroxylamine substituted thiazolo(4,5-c) ring compounds and methods
|
|
JP2008532933A
(ja)
|
2005-02-11 |
2008-08-21 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
置換イミダゾキノリン類および置換イミダゾナフチリジン類
|
|
WO2006086634A2
(en)
|
2005-02-11 |
2006-08-17 |
Coley Pharmaceutical Group, Inc. |
Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
|
|
EP2298795A1
(en)
|
2005-02-18 |
2011-03-23 |
Novartis Vaccines and Diagnostics, Inc. |
Immunogens from uropathogenic escherichia coli
|
|
NZ561042A
(en)
|
2005-02-18 |
2011-03-31 |
Novartis Vaccines & Diagnostic |
Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli - SEQ ID: 7052
|
|
US8846710B2
(en)
|
2005-02-23 |
2014-09-30 |
3M Innovative Properties Company |
Method of preferentially inducing the biosynthesis of interferon
|
|
WO2006098852A2
(en)
|
2005-02-23 |
2006-09-21 |
Coley Pharmaceutical Group, Inc. |
Hydroxyalkyl substituted imidazoquinolines
|
|
AU2006216799A1
(en)
|
2005-02-23 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Hydroxyalkyl substituted imidazonaphthyridines
|
|
JP2008531567A
(ja)
|
2005-02-23 |
2008-08-14 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
ヒドロキシアルキル置換イミダゾキノリン化合物および方法
|
|
EP1865957A4
(en)
|
2005-03-14 |
2009-05-06 |
Meda Ab |
METHOD FOR TREATING RADIATION KERATOSIS
|
|
WO2006107853A2
(en)
|
2005-04-01 |
2006-10-12 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridine-1,4-diamines and analogs thereof
|
|
EP1863814A1
(en)
|
2005-04-01 |
2007-12-12 |
Coley Pharmaceutical Group, Inc. |
1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
|
|
AU2006241166A1
(en)
*
|
2005-04-25 |
2006-11-02 |
3M Innovative Properties Company |
Immunostimulatory compositions
|
|
CA2615626A1
(en)
|
2005-07-18 |
2007-01-25 |
Novartis Ag |
Small animal model for hcv replication
|
|
ZA200803029B
(en)
|
2005-09-09 |
2009-02-25 |
Coley Pharm Group Inc |
Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
|
|
CA2621831A1
(en)
|
2005-09-09 |
2007-03-15 |
Coley Pharmaceutical Group, Inc. |
Amide and carbamate derivatives of n-{2-[4-amino-2- (ethoxymethyl)-1h-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide and methods
|
|
US8889154B2
(en)
|
2005-09-15 |
2014-11-18 |
Medicis Pharmaceutical Corporation |
Packaging for 1-(2-methylpropyl)-1H-imidazo[4,5-c] quinolin-4-amine-containing formulation
|
|
TW200801003A
(en)
*
|
2005-09-16 |
2008-01-01 |
Astrazeneca Ab |
Novel compounds
|
|
JP2009514839A
(ja)
|
2005-11-04 |
2009-04-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
サイトカイン誘導剤を含むアジュバントインフルエンザワクチン
|
|
ES2792398T3
(es)
|
2005-11-04 |
2020-11-11 |
Seqirus Uk Ltd |
Vacunas adyuvantadas con antígenos de no virión preparadas a partir de virus de la gripe cultivados en cultivo celular
|
|
CN101309687A
(zh)
|
2005-11-04 |
2008-11-19 |
科勒制药集团公司 |
经羟基和烷氧基取代的1h-咪唑并喹啉及其方法
|
|
ATE539765T1
(de)
|
2005-11-04 |
2012-01-15 |
Novartis Vaccines & Diagnostic |
Grippeimpfstoffe mit kombinationen aus teilchenförmigen adjuvantien und immunverstärkern
|
|
US20090304742A1
(en)
|
2005-11-04 |
2009-12-10 |
Novartis Vaccines And Diagnostics Srl |
Influenza vaccines with reduced amount of emulsion adjuvant
|
|
WO2007079203A2
(en)
*
|
2005-12-28 |
2007-07-12 |
3M Innovative Properties Company |
Treatment for cutaneous t cell lymphoma
|
|
US20110027314A1
(en)
|
2006-01-27 |
2011-02-03 |
Novartis Vaccines And Diagnostics Gmbh & Co. Kg |
Influenza Vaccines Containing Hemagglutinin and Matrix Proteins
|
|
US8951528B2
(en)
|
2006-02-22 |
2015-02-10 |
3M Innovative Properties Company |
Immune response modifier conjugates
|
|
WO2007106854A2
(en)
|
2006-03-15 |
2007-09-20 |
Coley Pharmaceutical Group, Inc. |
Hydroxy and alkoxy substituted 1h-imidazonaphthyridines and methods
|
|
AU2007228887B2
(en)
*
|
2006-03-22 |
2012-02-02 |
F. Hoffmann-La Roche Ag |
Pyrazoles as 11-beta-HSD-1
|
|
WO2007109812A2
(en)
*
|
2006-03-23 |
2007-09-27 |
Novartis Ag |
Immunopotentiating compounds
|
|
US8173657B2
(en)
*
|
2006-03-23 |
2012-05-08 |
Novartis Ag |
Imidazoquinoxaline compounds as immunomodulators
|
|
CA2647100A1
(en)
*
|
2006-03-23 |
2007-09-27 |
Novartis Ag |
Methods for the preparation of imidazole-containing compounds
|
|
CA2646349A1
(en)
|
2006-03-24 |
2007-10-04 |
Novartis Vaccines And Diagnostics Gmbh & Co Kg |
Storage of influenza vaccines without refrigeration
|
|
SG173336A1
(en)
|
2006-03-31 |
2011-08-29 |
Novartis Ag |
Combined mucosal and parenteral immunization against hiv
|
|
PT2054431E
(pt)
|
2006-06-09 |
2011-11-03 |
Novartis Ag |
Confórmeros de adesinas bacterianas
|
|
CA2656266C
(en)
*
|
2006-06-20 |
2012-07-31 |
Transgene S.A. |
Recombinant viral vaccine
|
|
US8138172B2
(en)
|
2006-07-05 |
2012-03-20 |
Astrazeneca Ab |
8-oxoadenine derivatives acting as modulators of TLR7
|
|
WO2008008432A2
(en)
|
2006-07-12 |
2008-01-17 |
Coley Pharmaceutical Group, Inc. |
Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
|
|
GB0614460D0
(en)
|
2006-07-20 |
2006-08-30 |
Novartis Ag |
Vaccines
|
|
JP2010500399A
(ja)
|
2006-08-16 |
2010-01-07 |
ノバルティス アーゲー |
尿路病原性大腸菌由来の免疫原
|
|
WO2008030511A2
(en)
|
2006-09-06 |
2008-03-13 |
Coley Pharmaceuticial Group, Inc. |
Substituted 3,4,6,7-tetrahydro-5h, 1,2a,4a,8-tetraazacyclopenta[cd]phenalenes
|
|
WO2008032219A2
(en)
|
2006-09-11 |
2008-03-20 |
Novartis Ag |
Making influenza virus vaccines without using eggs
|
|
JP2010511647A
(ja)
*
|
2006-12-05 |
2010-04-15 |
トランジェーヌ、ソシエテ、アノニム |
改良された免疫応答を向上させる手段および方法
|
|
CN101553252A
(zh)
|
2006-12-06 |
2009-10-07 |
诺华有限公司 |
包含来自于四株流感病毒的抗原的疫苗
|
|
TW200831105A
(en)
|
2006-12-14 |
2008-08-01 |
Astrazeneca Ab |
Novel compounds
|
|
US20080149123A1
(en)
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
DK2102192T3
(da)
|
2006-12-29 |
2013-03-04 |
Il Yang Pharmaceutical Company Ltd |
Racemisk ilaprazol i fast form
|
|
GB0700562D0
(en)
|
2007-01-11 |
2007-02-21 |
Novartis Vaccines & Diagnostic |
Modified Saccharides
|
|
EP2132209B8
(en)
|
2007-03-19 |
2014-04-16 |
AstraZeneca AB |
9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7 ) modulators
|
|
EP2139894B1
(en)
|
2007-03-19 |
2011-10-26 |
AstraZeneca AB |
9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
|
|
JPWO2008114819A1
(ja)
|
2007-03-20 |
2010-07-08 |
大日本住友製薬株式会社 |
新規アデニン化合物
|
|
TW200902018A
(en)
*
|
2007-03-20 |
2009-01-16 |
Dainippon Sumitomo Pharma Co |
Novel adenine compound
|
|
PT2155743E
(pt)
*
|
2007-05-08 |
2012-10-30 |
Astrazeneca Ab |
Imidazoquinolinas com propriedades imunomoduladoras
|
|
SG182957A1
(en)
|
2007-06-27 |
2012-08-30 |
Novartis Ag |
Low-additive influenza vaccines
|
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
|
GB0810305D0
(en)
|
2008-06-05 |
2008-07-09 |
Novartis Ag |
Influenza vaccination
|
|
UY31531A1
(es)
|
2007-12-17 |
2009-08-03 |
|
Sales derivadas de 8-oxoadenina composiciones farmacéuticas que las contienen y su uso en terapia como moduladores de receptor tipo toll (tlr)
|
|
GB0818453D0
(en)
|
2008-10-08 |
2008-11-12 |
Novartis Ag |
Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
|
|
CN101998990B
(zh)
|
2008-03-18 |
2013-11-27 |
诺华股份有限公司 |
流感病毒疫苗抗原制备方法的改进
|
|
RU2372916C1
(ru)
*
|
2008-08-14 |
2009-11-20 |
Общество с ограниченной ответственностью "ИФОХИМ" |
Применение 6-окси-2,2,4-триметил-1,2-дигидрохинолина или 6-окси-2,2,4-триметил-1,2,3,4-тетрагидрохинолина в качестве противотуберкулезного вещества
|
|
SG173065A1
(en)
|
2009-01-20 |
2011-08-29 |
Transgene Sa |
Soluble icam-1 as biomarker for prediction of therapeutic response
|
|
AU2010220103A1
(en)
|
2009-03-06 |
2011-09-22 |
Novartis Ag |
Chlamydia antigens
|
|
CA2756133A1
(en)
|
2009-03-24 |
2010-09-30 |
Transgene S.A. |
Biomarker for monitoring cancer patients
|
|
EP2411521B1
(en)
|
2009-03-25 |
2015-01-14 |
The Board of Regents of The University of Texas System |
Compositions for stimulation of mammalian innate immune resistance to pathogens
|
|
NZ612315A
(en)
|
2009-04-14 |
2014-10-31 |
Novartis Ag |
Compositions for immunising against staphylococcus aureus
|
|
MX2011010920A
(es)
|
2009-04-17 |
2011-11-04 |
Transgene Sa |
Biomarcador para monitorear pacientes.
|
|
EP2424565A1
(en)
|
2009-04-27 |
2012-03-07 |
Novartis AG |
Adjuvanted vaccines for protecting against influenza
|
|
ES2558729T3
(es)
|
2009-07-10 |
2016-02-08 |
Transgene Sa |
Biomarcador para la selección de pacientes y procedimientos relacionados
|
|
SG178026A1
(en)
|
2009-07-15 |
2012-03-29 |
Novartis Ag |
Rsv f protein compositions and methods for making same
|
|
US8871214B2
(en)
|
2009-07-16 |
2014-10-28 |
Novartis Ag |
Detoxified Escherichia coli immunogens
|
|
US20110033515A1
(en)
*
|
2009-08-04 |
2011-02-10 |
Rst Implanted Cell Technology |
Tissue contacting material
|
|
GB0918392D0
(en)
|
2009-10-20 |
2009-12-02 |
Novartis Ag |
Diagnostic and therapeutic methods
|
|
GB0919690D0
(en)
|
2009-11-10 |
2009-12-23 |
Guy S And St Thomas S Nhs Foun |
compositions for immunising against staphylococcus aureus
|
|
JP2013512859A
(ja)
*
|
2009-12-03 |
2013-04-18 |
大日本住友製薬株式会社 |
トール様受容体(tlr)を介して作用するイミダゾキノリン
|
|
NO2575876T3
(OSRAM)
|
2010-05-26 |
2018-05-05 |
|
|
|
GB201009861D0
(en)
|
2010-06-11 |
2010-07-21 |
Novartis Ag |
OMV vaccines
|
|
WO2012024284A1
(en)
|
2010-08-17 |
2012-02-23 |
3M Innovative Properties Company |
Lipidated immune response modifier compound compositions, formulations, and methods
|
|
EP2640190A4
(en)
|
2010-11-05 |
2016-05-11 |
Selecta Biosciences Inc |
MODIFIED NICOTINIC COMPOUNDS AND ASSOCIATED METHODS
|
|
JP5978225B2
(ja)
|
2010-12-16 |
2016-08-24 |
大日本住友製薬株式会社 |
治療に有用なイミダゾ[4,5−c]キノリン−1−イル誘導体
|
|
US8895570B2
(en)
|
2010-12-17 |
2014-11-25 |
Astrazeneca Ab |
Purine derivatives
|
|
EP3527224B1
(en)
|
2011-01-26 |
2025-02-26 |
GlaxoSmithKline Biologicals S.A. |
Rsv immunization regimen
|
|
BR112013029169B1
(pt)
|
2011-05-13 |
2021-09-28 |
Novartis Ag |
Polipeptídeo f pré-fusão do vírus sincicial respiratório (rsv), composição imunogênica e uso da mesma
|
|
US8728486B2
(en)
|
2011-05-18 |
2014-05-20 |
University Of Kansas |
Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds
|
|
JP6460789B2
(ja)
|
2011-06-03 |
2019-01-30 |
スリーエム イノベイティブ プロパティズ カンパニー |
ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体
|
|
JP6415979B2
(ja)
|
2011-06-03 |
2018-10-31 |
スリーエム イノベイティブ プロパティズ カンパニー |
ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体
|
|
WO2012174549A2
(en)
*
|
2011-06-16 |
2012-12-20 |
Children's Hospital Medical Center |
Blockade of eosinophil production by toll-like receptors
|
|
US20130023736A1
(en)
|
2011-07-21 |
2013-01-24 |
Stanley Dale Harpstead |
Systems for drug delivery and monitoring
|
|
US9493517B2
(en)
|
2011-11-07 |
2016-11-15 |
Glaxosmithkline Biologicals Sa |
Conjugates comprising an antigen and a carrier molecule
|
|
WO2013108272A2
(en)
|
2012-01-20 |
2013-07-25 |
International Centre For Genetic Engineering And Biotechnology |
Blood stage malaria vaccine
|
|
NZ701324A
(en)
|
2012-05-04 |
2016-09-30 |
Pfizer |
Prostate-associated antigens and vaccine-based immunotherapy regimens
|
|
CN112587658A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
|
CN105025854A
(zh)
|
2013-01-07 |
2015-11-04 |
宾夕法尼亚大学董事会 |
治疗皮肤t细胞淋巴瘤的组合物和方法
|
|
EP3632458B1
(en)
|
2013-07-26 |
2025-03-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of bacterial infections
|
|
RU2687279C2
(ru)
|
2013-11-05 |
2019-05-13 |
3М Инновейтив Пропертиз Компани |
Инъекционные композиции на основе кунжутного масла
|
|
EP2870974A1
(en)
|
2013-11-08 |
2015-05-13 |
Novartis AG |
Salmonella conjugate vaccines
|
|
SG11201605449YA
(en)
|
2014-01-10 |
2016-08-30 |
Birdie Biopharmaceuticals Inc |
Compounds and compositions for immunotherapy
|
|
CN112521464A
(zh)
|
2014-03-26 |
2021-03-19 |
葛兰素史密丝克莱恩生物有限公司 |
突变型葡萄球菌抗原
|
|
CN112546230A
(zh)
|
2014-07-09 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗癌症的联合治疗组合物和联合治疗方法
|
|
EP4001311B1
(en)
|
2014-07-09 |
2025-11-05 |
Birdie Biopharmaceuticals Inc. |
Anti-pd-l1/pd-1 combinations for treating tumors
|
|
CN112546238A
(zh)
|
2014-09-01 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
US10286065B2
(en)
|
2014-09-19 |
2019-05-14 |
Board Of Regents, The University Of Texas System |
Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
|
WO2016180852A1
(en)
|
2015-05-12 |
2016-11-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for preparing antigen-specific t cells from an umbilical cord blood sample
|
|
ES2952603T3
(es)
|
2015-05-20 |
2023-11-02 |
Univ California |
Método para generar células dendríticas humanas para inmunoterapia
|
|
WO2017040233A1
(en)
|
2015-08-31 |
2017-03-09 |
3M Innovative Properties Company |
GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS
|
|
CN107922416B
(zh)
|
2015-08-31 |
2021-07-02 |
3M创新有限公司 |
含有取代的胍基团的咪唑并[4,5-c]环化合物
|
|
US10526309B2
(en)
|
2015-10-02 |
2020-01-07 |
The University Of North Carolina At Chapel Hill |
Pan-TAM inhibitors and Mer/Axl dual inhibitors
|
|
TW202344686A
(zh)
|
2015-10-30 |
2023-11-16 |
美國加利福尼亞大學董事會 |
從幹細胞產生t細胞之方法及使用該t細胞之免疫療法
|
|
CN106943597A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-egfr组合
|
|
CN106943596A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-cd20组合
|
|
CN115350279A
(zh)
|
2016-01-07 |
2022-11-18 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-her2组合
|
|
EP3402572B1
(en)
|
2016-01-13 |
2022-03-16 |
Children's Hospital Medical Center |
Compositions and methods for treating allergic inflammatory conditions
|
|
CA3029902A1
(en)
|
2016-07-07 |
2018-01-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Antibody adjuvant conjugates
|
|
JP7010286B2
(ja)
|
2016-08-26 |
2022-01-26 |
スリーエム イノベイティブ プロパティズ カンパニー |
グアニジノ基で置換された縮合[1,2]イミダゾ[4,5-c]環状化合物
|
|
JP7145853B2
(ja)
|
2016-11-09 |
2022-10-03 |
ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム |
適応免疫調節のための方法および組成物
|
|
EP3589631B1
(en)
|
2017-03-01 |
2021-07-21 |
3M Innovative Properties Company |
Imidazo[4,5-c]ring compounds containing guanidine substituted benzamide groups
|
|
CN118515666A
(zh)
|
2017-04-27 |
2024-08-20 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
|
US11517567B2
(en)
|
2017-06-23 |
2022-12-06 |
Birdie Biopharmaceuticals, Inc. |
Pharmaceutical compositions
|
|
US11306083B2
(en)
|
2017-12-20 |
2022-04-19 |
3M Innovative Properties Company |
Amide substituted imidazo[4,5-C]quinoline compounds with a branched chain linking group for use as an immune response modifier
|
|
US11859250B1
(en)
|
2018-02-23 |
2024-01-02 |
Children's Hospital Medical Center |
Methods for treating eosinophilic esophagitis
|
|
CA3034912A1
(en)
|
2018-02-28 |
2019-08-28 |
Pfizer Inc. |
Il-15 variants and uses thereof
|
|
JP7251893B2
(ja)
|
2018-02-28 |
2023-04-04 |
スリーエム イノベイティブ プロパティズ カンパニー |
N-1分枝基を有する置換イミダゾ[4,5-c]キノリン化合物
|
|
EP3781588B1
(en)
|
2018-04-20 |
2024-10-30 |
Children's Hospital Medical Center |
Blood biomarker for eosinophilic gastrointestinal disorders
|
|
BR112020022897A2
(pt)
|
2018-05-23 |
2021-02-23 |
Pfizer Inc. |
anticorpos específicos para cd3 e usos dos mesmos
|
|
US11525010B2
(en)
|
2018-05-23 |
2022-12-13 |
Pfizer Inc. |
Antibodies specific for GUCY2c and uses thereof
|
|
JP7394790B2
(ja)
|
2018-05-24 |
2023-12-08 |
スリーエム イノベイティブ プロパティズ カンパニー |
N-1分枝状シクロアルキル置換イミダゾ[4,5-c]キノリン化合物、組成物、及び方法
|
|
US12024514B2
(en)
|
2018-11-26 |
2024-07-02 |
Solventum Intellectual Properties Company |
N-1 branched alkyl ether substituted imidazo[4,5-c]quinoline compounds, compositions, and methods
|
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
|
CN119455003A
(zh)
|
2019-02-12 |
2025-02-18 |
Ambrx公司 |
包含抗体-tlr激动剂缀合物的组合物、方法和用途
|
|
US12297501B2
(en)
|
2019-02-25 |
2025-05-13 |
Children's Hospital Medical Center |
Methods for diagnosing and treating eosinophilic gastritis
|
|
JP2022525594A
(ja)
|
2019-03-15 |
2022-05-18 |
ボルト バイオセラピューティクス、インコーポレーテッド |
Her2を標的とする免疫結合体
|
|
WO2020245706A1
(en)
|
2019-06-06 |
2020-12-10 |
3M Innovative Properties Company |
N-1 branched alkyl substituted imidazo[4,5-c]quinoline compounds, compositions, and methods
|
|
EP3983408A1
(en)
|
2019-06-12 |
2022-04-20 |
3M Innovative Properties Company |
Phenethyl substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group
|
|
WO2021116420A1
(en)
|
2019-12-13 |
2021-06-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tlr7 and/or tlr8 agonists for the treatment of leptospirosis
|
|
US11702474B2
(en)
|
2019-12-17 |
2023-07-18 |
Pfizer Inc. |
Antibodies specific for CD47, PD-L1, and uses thereof
|
|
JP2023533793A
(ja)
|
2020-07-17 |
2023-08-04 |
ファイザー・インク |
治療用抗体およびそれらの使用
|
|
AU2021327396A1
(en)
|
2020-08-20 |
2023-03-23 |
Ambrx, Inc. |
Antibody-TLR agonist conjugates, methods and uses thereof
|
|
WO2025104289A1
(en)
|
2023-11-17 |
2025-05-22 |
Medincell S.A. |
Antineoplastic combinations
|